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maldescended testis

J van Brakel, S M P F de Muinck Keizer-Schrama, N J van Casteren, F W Hazebroek, G R Dohle
The aim of this study was to report on different anomalies found by physical examination and scrotal ultrasound in men with previously unilateral congenital undescended testes (UDT; N = 50), acquired UDT (N = 49), their contralateral normally descended testis (CNDT) and control testes (N = 53). Acquired UDT significantly more often had a testicular volume being <15 mL than congenital UDT (88% vs. 68%). In the congenital group, significant differences were found between UDT and CNDT for soft consistency (UDT 36% vs...
September 2015: Andrology
Seshadri Sekhar Chatterjee, Prathama Guha, Arunansu Talukdar, Gargi Dasgupta
Although mental retardation is generally associated with Bardet-Biedl (BBS) syndrome, a rare autosomal recessive disorder with multisystem involvement, autism is an unusual comorbidity. An 8-year-old boy presented to our psychiatry department with poor social skills and night blindness. On further assessment autism, mild mental retardation, retinitis pigmentosa, polydactyly and syndactyly, obesity, micropenis, maldescended testis, hypodontia and high-arched palate were noted and subsequently a diagnosis of BBS was made...
2014: BMJ Case Reports
Trupti Tonape, Gurjit Singh, P Koushik, Trinath Tumepalli
Polyorchidism is an extremely rare congenital anomaly which refers to the presence of more than two testicles. There are very few reports of triorchidism in a 2 year old child. Polyorchidism is usually discovered incidentally. The most common anomalies associated with polyorchidism are inguinal hernia (30%), maldescended testis (15% to 30%), testicular torsion (13%) and hydrocele (9%). A 2-year-old child was brought with bilateral undescended testis with normal milestones. Ultrasonography of scrotum and abdomen showed both the testes to be in inguinal canal...
July 2012: Journal of Surgical Technique and Case Report
Nathalie Rives, Anne Perdrix, Sylviane Hennebicq, Jacqueline Saïas-Magnan, Marie-Claude Melin, Isabelle Berthaut, Claire Barthélémy, Myriam Daudin, Ethel Szerman, Jean-Luc Bresson, Florence Brugnon, Louis Bujan
Testicular cancer is the most common cancer in young men. Several studies have reported an alteration in semen quality in nonseminoma tumors, but this result has not been confirmed in all of the published data. We performed a retrospective study in a population of 1158 men with testicular cancer who banked sperm between 1999 and 2003 in 11 French Centre d'Etude et de Conservation des Oeufs et du Sperme humain laboratories. Our study evaluated prefreeze and postthaw sperm parameters according to patient medical history, tumor histological type, and disease stage...
November 2012: Journal of Andrology
Katarina Aleksa, Amanda Carnevale, Cynthia Goodyer, Gideon Koren
INTRODUCTION: Cryptorchidism, or undescended/maldescended testis, is the most common birth defect of male genitalia. Its prevalence has been increasing over the past few decades. This may be due to an increase in the prevalence of anti-androgenic chemicals such as polychlorinated biphenyls, organochloride pesticides, plasticizers and fungicides. A newer group of chemicals, brominated flame retardants (BFRs), are being implicated as endocrine-disrupting chemicals. These chemicals are used worldwide in polymers that are incorporated into a variety of consumer products (e...
May 10, 2012: Forensic Science International
Ghizlane G Raiss, Marwane M Benatiya Andaloussi, Soundouss S Raissouni, Hind H Mrabti, Hassan H Errihani
BACKGROUND: Spermatocytic seminoma (SS) is a distinct testicular germ cell tumor, representing less than 1% of testicular cancers. The clinical features that distinguish ss from classical seminoma are an older age at presentation and a reduced propensity to metastasize. The aim of our work is to underline the epidemiological, clinical, histological, therapeutical and prognostic features of this tumor. FINDINGS: A retrospective analysis of patients referred to the national institute of oncology with seminoma, identified from the institutional tumor registry, between January 1996 and February 2009, was performed...
2011: BMC Research Notes
Oc Osime, Mi Momoh, So Elusoji
Cryptorchidism, or maldescended testis, is a common problem encountered in pediatric age groups. Despite more than 100 years of research, many aspects of cryptorchidism are not well defined and remain controversial. However, cryptorchidism clearly has deleterious effects on the testis over time.(1-4)Among the problems associated with an undescended testis are an increased risk for testicular tumor development and a propensity for torsion. In cases of bilateral undescended testis, infertility is a concern.(1-4)Torsed intraabdominal testis is rarely considered in the differential of acute appendicitis, probably because of a failure to examine the external genitalia as part of the abdominal examination...
2006: California Journal of Emergency Medicine
Altaf Hussain Shera, Aejaz Ahsan Baba, Shyam Kumar Gupta, Geetanjali Gupta, Afak Yusuf Sherwani
AIM: The aim of this study was to highlight various anomalies associated with undescended testis and to determine how much work up is necessary for this condition. MATERIAL AND METHODS: The study was conducted in the department of Pediatric Surgery SKIMS Srinagar, Kashmir. All patients between 0-14 years of age who attended out patient department (OPD) from January 2002 to December 2003 with maldescent of testes were included in the study. Detailed relevant history and physical examination findings were recorded in all the cases...
May 2010: African Journal of Paediatric Surgery: AJPS
M C Veronesi, E Riccardi, A Rota, V Grieco
Testicular malposition represents a common developmental genital defect in dogs and can affect one or both testes. In both humans and dogs, unilateral cryptorchism is more frequently detected and thought to be the expression of a genetic abnormality affecting both the undescended and scrotal testis. In the dog, there is evidence of degenerative processes affecting the maldescended testis. However, the histologic and functional changes that occur in the scrotal testis of unilateral cryptorchid or ectopic individuals remain a source of debate...
October 15, 2009: Theriogenology
Manuela Simoni, Frank Tüttelmann, Caroline Michel, Yvonne Böckenfeld, Eberhard Nieschlag, Jörg Gromoll
OBJECTIVE: Maldescended testes are the most common genital anomaly in newborns and are associated with testicular malignancy and infertility. As the inguinoscrotal phase of testis descent is androgen-dependent and requires integrity of the luteinizing hormone/chorionic gonadotropin receptor (LHCGR), we investigated whether nonsynonymous polymorphisms of the LHCGR gene are associated with maldescended testes. METHODS: This was a retrospective case-control study including 278 patients with maldescended testes, 277 infertile men without maldescensus and 271 controls with normal sperm concentrations...
March 2008: Pharmacogenetics and Genomics
W B Coley
No abstract text is available yet for this article.
September 1908: Annals of Surgery
C Cristián Palma, B Cristóbal, R Maccioni
OBJECTIVE: To present a new case of an Intra-abdominal Testicular Seminoma in an adult. METHODS/RESULTS: We report a 30 year old patient with cryptochidism, that after consulting to the emergency service due to abdominal pain, was diagnosed an Intra-abdominal Testicular Seminoma. DISCUSSION: The incidence of testicular cancer in cryptorchidic testis is 3 to 48 times higher than in general population. The existence of maldescended testis in adult population is rare in developed countries, due to the normal practice of elective orchidopexia in children under 2 years old and orchiectomy in maldecended testis in postpuberal pacients...
February 2007: Actas Urologicas Españolas
Pernille Kure Vandborg, Morten Jønler, Lars Lund
No abstract text is available yet for this article.
March 5, 2007: Ugeskrift for Laeger
A Ferlin, N V Bogatcheva, L Gianesello, A Pepe, C Vinanzi, A I Agoulnik, C Foresta
Insulin-like factor 3 (INSL3) plays a crucial role in testicular descent. Genetic ablation of Insl3 or its G protein-coupled receptor, leucine-rich repeat-containing G-protein-coupled receptor (Lgr8), causes cryptorchidism in mice. Mutation analyses of INSL3 in humans showed an association with cryptorchidism but led to non-conclusive data about a causative role. In this study, we explored the hypothesis that mutations in INSL3 may be associated with the signs of testicular dysgenesis syndrome (TDS). We screened for mutations in INSL3 gene in 967 subjects with a history of maldescended testes and/or infertility and/or testicular cancer and in 450 controls...
June 2006: Molecular Human Reproduction
E A Granados Loarca, S Esau Ortega
OBJECTIVE: The cryptorchidism is a risk factor for testicular cancer and is associated with cancer in the contraleteral testicle. The mechanism that leads to an increased risk of causes in a cryptorchid testis is unclear. MATERIALS AND METHODS: We analyzed 25 patients of 20-years old for maldescended testicles we practiced orchiectomy in 22 testicles and orchiopexy in 7 testicles. The time patients had the testicles in an anomalous location were between 20-51 years...
November 2005: Actas Urologicas Españolas
R Kucheria, A Sahai, T A Sami, B Challacombe, H Godbole, M S Khan, P Dasgupta
OBJECTIVES: Little is reported on the management of impalpable testis in adults. We present the impact of laparoscopy in this patient group. PATIENTS AND METHODS: Twelve adult patients have been referred to our centre over the last year, with impalpable testis. Pre-operative assessment was by either ultrasound or magnetic resonance imaging (MRI) or both. Quality of life and patient satisfaction were assessed by validated SF8 and client satisfaction (CSQ-8) questionnaires...
September 2005: European Urology
Finn Edler von Eyben, Grete Krag Jacobsen, Rolf Inge Skotheim
Microinvasive germ cell tumor (MGCT) consists of a limited number of malignant germ cells in the intertubular tissue of the testis. The cells have large nuclei, prominent nucleoli, abundant clear cytoplasm, and distinct cellular borders in hematoxylin and eosin staining. MGCT can be the first stage of malignancy in the development of testicular germ cell tumor (TGCT). Biopsies from men with maldescended testes have been reported to contain intratubular germ cell neoplasia, unclassified (IGCN) and MGCT in 1...
September 2005: Virchows Archiv: An International Journal of Pathology
V Raveenthiran
Nearly 28% of pediatric Spigelian hernias reported in the literature are associated with ipsilateral cryptorchidism. However, the pathogenetic relationship between the two has not been satisfactorily explained in the past. This paper describes a male neonate born with cryptorchidism and imperforate anus. Anal stenosis following the treatment of imperforate anus had let to the development of multiple hernias including Spigelian hernia on the right side. Surgical exploration revealed the right testis being located within the Spigelian hernia...
December 2005: Hernia: the Journal of Hernias and Abdominal Wall Surgery
P A Fall, S M Gueye, A Ndoye, C Sylla, M O Abdallahi, A A Diame, M Ba, B A Diagne
The objective of this work was to describe the clinical and therapeutical aspects of pathology of the peritoneo-vaginal process. We have performed a retrospective study including 160 patients operated between January 1990 up to December 1996. Mean age at diagnosis was 8 years, ranged from 1 month to 13 years old. All patients were male. The abnormality was located in the right side in 60% of cases and was bilateral in 6.7% of cases. The main clinical features were scrotal mass (81%) and scrotal pain (13.46%)...
2000: Dakar Médical
M F O'Brien, P K Hegarty, C Healy, D DeFrietas, H C Bredin
BACKGROUND: The Fowler-Stephens orchidopexy (FSO) is a well-described treatment for high maldescended testes where the limiting factor for successful placement in the scrotum is short testicular vessels. The operation involves division of these vessels. The testicular blood supply is then dependent on collaterals from the vasal artery. AIMS: To assess the long-term outcome of patients who underwent this procedure in our institution. METHODS: The medical records of 20 patients who underwent 22 FSO from 1978 to 1999 by one urologist (HB) were reviewed...
January 2004: Irish Journal of Medical Science
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