Fernando Sorroche, Violette Morales, Saïda Mouffok, Carole Pichereaux, A Marie Garnerone, Lan Zou, Badrish Soni, Marie-Anne Carpéné, Audrey Gargaros, Fabienne Maillet, Odile Burlet-Schiltz, Verena Poinsot, Patrice Polard, Clare Gough, Jacques Batut
We recently described a regulatory loop, which we termed autoregulation of infection (AOI), by which Sinorhizobium meliloti, a Medicago endosymbiont, downregulates the root susceptibility to secondary infection events via ethylene. AOI is initially triggered by so-far unidentified Medicago nodule signals named signal 1 and signal 1' whose transduction in bacteroids requires the S. meliloti outer-membrane-associated NsrA receptor protein and the cognate inner-membrane-associated adenylate cyclases, CyaK and CyaD1/D2, respectively...
2020: PloS One