keyword
https://read.qxmd.com/read/36519620/paracetamol-acetaminophen-for-patent-ductus-arteriosus-in-preterm-or-low-birth-weight-infants
#1
REVIEW
Bonny Jasani, Souvik Mitra, Prakeshkumar S Shah
BACKGROUND: The different management strategies for patent ductus arteriosus (PDA) in preterm infants are expectant management, surgery, or medical treatment with non-selective cyclo-oxygenase inhibitors. Randomized controlled trials (RCTs) have suggested that paracetamol may be an effective and safe agent for the closure of a PDA. OBJECTIVES: To determine the efficacy and safety of paracetamol as monotherapy or as part of combination therapy via any route of administration, compared with placebo, no intervention, or another prostaglandin inhibitor, for prophylaxis or treatment of an echocardiographically-diagnosed PDA in preterm or low birth weight infants...
December 15, 2022: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/34352883/elbw-and-elgan-outcomes-in-developing-nations-systematic-review-and-meta-analysis
#2
JOURNAL ARTICLE
Viraraghavan Vadakkencherry Ramaswamy, Thangaraj Abiramalatha, Tapas Bandyopadhyay, Nasreen Banu Shaik, Prathik Bandiya, Debasish Nanda, Abdul Kareem Pullattayil S, Srinivas Murki, Charles Christoph Roehr
CONTEXT: Morbidity and mortality amongst extremely low birth weight (ELBW) and extremely low gestational age neonates (ELGANs) in developing nations has not been well studied. OBJECTIVES: Evaluate survival until discharge, short- and long-term morbidities of ELBW and ELGANs in LMICs. DATA SOURCES: CENTRAL, EMBASE, MEDLINE and Web of Science. STUDY SELECTION: Prospective and retrospective observational studies were included...
2021: PloS One
https://read.qxmd.com/read/34136218/extreme-prematurity-and-sepsis-strongly-influence-frequencies-and-functional-characteristics-of-circulating-%C3%AE-%C3%AE-t-and-natural-killer-cells
#3
JOURNAL ARTICLE
Khaleda Rahman Qazi, Georg B Jensen, Marieke van der Heiden, Sophia Björkander, Giovanna Marchini, Maria C Jenmalm, Thomas Abrahamsson, Eva Sverremark-Ekström
Objectives: Extremely low gestational age neonates with extremely low birthweight (ELGAN/ELBW) are highly susceptible to infection. This is linked to their relatively immature immune system which is not yet fully compatible with an extra-uterine environment. Here, we performed a longitudinal characterisation of unconventional T and natural killer (NK) cells in ELGAN/ELBW during their first months of life. Methods: Peripheral blood mononuclear cells were collected from 97 ELGAN/ELBW at 14 and 28 days of life and at a time point corresponding to postmenstrual week 36 + 0...
2021: Clinical & Translational Immunology
https://read.qxmd.com/read/31801814/extremely-preterm-infants-have-significant-alterations-in-their-conventional-t-cell-compartment-during-the-first-weeks-of-life
#4
JOURNAL ARTICLE
Khaleda Rahman Qazi, Georg Bach Jensen, Marieke van der Heiden, Sophia Björkander, Ulrika Holmlund, Yeneneh Haileselassie, Efthymia Kokkinou, Giovanna Marchini, Maria C Jenmalm, Thomas Abrahamsson, Eva Sverremark-Ekström
Extremely preterm neonates are particularly susceptible to infections, likely because of severely impaired immune function. However, little is known on the composition of the T cell compartment in early life in this vulnerable population. We conducted a comprehensive phenotypic flow cytometry-based longitudinal analysis of the peripheral conventional T cell compartment of human extremely low gestational age neonates (ELGAN) with extremely low birth weight (ELBW; <1000 g) participating in a randomized placebo-controlled study of probiotic supplementation...
December 4, 2019: Journal of Immunology
https://read.qxmd.com/read/28756708/biomarkers-of-necrotizing-enterocolitis-a-review-of-literature
#5
JOURNAL ARTICLE
Bhawan Deep Garg, Deepak Sharma, Anju Bansal
Necrotizing enterocolitis (NEC) is among the most serious gastrointestinal emergency in very low birth weight (VLBW), extremely low birth weight (ELBW) and extremely low gestational age neonates (ELGAN), affecting 7-14% of these neonates. Despite extensive research, the underlying aetiology of NEC still remains blurred. Due to high mortality, morbidity and its delayed presentation, early detection of NEC is considered to be lifesaving. A number of biomarkers have been studied for early detection and prediction of severity of NEC but till date, no ideal marker has been discovered...
November 2018: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/27445952/learning-disabilities-in-extremely-low-birth-weight-children-and-neurodevelopmental-profiles-at-preschool-age
#6
JOURNAL ARTICLE
Chiara Squarza, Odoardo Picciolini, Laura Gardon, Maria L Giannì, Alessandra Murru, Silvana Gangi, Ivan Cortinovis, Silvano Milani, Fabio Mosca
At school age extremely low birth weight (ELBW) and extremely low gestational age (ELGAN) children are more likely to show Learning Disabilities (LDs) and difficulties in emotional regulation. The aim of this study was to investigate the incidence of LDs at school age and to detect neurodevelopmental indicators of risk for LDs at preschool ages in a cohort of ELBW/ELGAN children with broadly average intelligence. All consecutively newborns 2001-2006 admitted to the same Institution entered the study. Inclusion criteria were BW < 1000 g and/or GA < 28 weeks...
2016: Frontiers in Psychology
https://read.qxmd.com/read/26786751/high-prevalence-of-abnormal-motor-repertoire-at-3-months-corrected-age-in-extremely-preterm-infants
#7
MULTICENTER STUDY
Toril Fjørtoft, Kari Anne I Evensen, Gunn Kristin Øberg, Nils Thomas Songstad, Cathrine Labori, Inger Elisabeth Silberg, Marianne Loennecken, Unn Inger Møinichen, Randi Vågen, Ragnhild Støen, Lars Adde
AIMS: To compare early motor repertoire between extremely preterm and term-born infants. An association between the motor repertoire and gestational age and birth weight was explored in extremely preterm infants without severe ultrasound abnormalities. METHODS: In a multicentre study, the early motor repertoire of 82 infants born extremely preterm (ELGAN:<28 weeks) and/or with extremely low birth weight (ELBW:<1000 g) and 87 term-born infants were assessed by the "Assessment of Motor Repertoire - 2 to 5 Months" (AMR) which is part of Prechtl's "General Movement Assessment", at 12 weeks post-term age...
March 2016: European Journal of Paediatric Neurology: EJPN
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