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Endometriosis surgery

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https://read.qxmd.com/read/30753695/the-association-between-hysterectomy-and-ovarian-cancer-risk-a-population-based-record-linkage-study
#1
Suzanne C Dixon-Suen, Penelope M Webb, Louise F Wilson, Karen Tuesley, Louise M Stewart, Susan J Jordan
Background: Recent studies have called into question the long-held belief that hysterectomy without oophorectomy protects against ovarian cancer. This population-based longitudinal record-linkage study aimed to explore this relationship, overall and by age at hysterectomy, time period, surgery type, and indication for hysterectomy. Methods: We followed the female adult Western Australian population (837,942 women) across a 27-year period using linked electoral, hospital, births, deaths, and cancer records...
February 11, 2019: Journal of the National Cancer Institute
https://read.qxmd.com/read/30753458/reduced-%C3%AE-2-6-sialylation-regulates-cell-migration-in-endometriosis
#2
Chloé Maignien, Pietro Santulli, Sandrine Chouzenoux, Iñaki Gonzalez-Foruria, Louis Marcellin, Ludivine Doridot, Mohammed Jeljeli, Philippe Grange, Fernando M Reis, Charles Chapron, Frédéric Batteux
STUDY QUESTION: Is endometriosis associated with aberrant sialylation patterns and what is the potential impact of such anomalies on cell migratory properties? SUMMARY ANSWER: The reduced α-2,6 sialylation patterns in the peritoneal fluid of endometriosis-affected women and in stromal and epithelial cells from endometriotic lesions could be associated with enhanced cell migration. WHAT IS KNOWN ALREADY: Endometriosis is considered to be a benign disease although, like cancer, it has the characteristic of being an invasive disease with cells that have an enhanced capacity to migrate...
February 12, 2019: Human Reproduction
https://read.qxmd.com/read/30737365/cyfra-21-1-and-placental-growth-factor-as-screening-markers-for-endometriosis
#3
Hye-Yon Cho, Min Sun Kyung
BACKGROUND This study evaluated the performance of serum CYFRA 21-1 and placental growth factor (PIGF) as screening markers for endometriosis. MATERIAL AND METHODS In this prospective study included 81 female patients who underwent laparoscopy to treat benign ovarian tumors. Serum samples were obtained from all study patients before surgery. Serum marker levels, including CYFRA 21-1, PIGF, cancer antigen (CA)125, CA19-9, and human epididymis protein 4 (HE4) were measured using a fluorescence immunoassay technique...
February 9, 2019: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/30732484/effect-of-laparoscopic-endometrioma-cystectomy-on-anti-m%C3%A3-llerian-hormone-amh-levels
#4
Yu Wang, Xiangyan Ruan, Dan Lu, Jie Sheng, Alfred O Mueck
OBJECTIVE: To investigate temporary or long-term changes of AMH after laparoscopic endometrioma cystectomy and its dependency on characteristics of endometriomas. METHODS: One hundred and seventy-one women, open-labeled prospective study; five groups divided according age ≤/> 35, uni-/bilateral, cyst ≤/> 7 cm, coagulation/suture surgery, stage III/IV; between- and within-group analyses after 1, 3, 6, and 12 months. RESULTS: After 12 months, compared to pretreament, AMH decreased significantly for patients with bilateral cysts, cyst size >7 cm and endometriosis stage IV...
February 7, 2019: Gynecological Endocrinology
https://read.qxmd.com/read/30723546/extra-uterine-low-grade-endometrioid-stromal-sarcoma-arising-from-ovarian-endometriosis-a-case-report-and-review-of-the-literature
#5
Boubacar Efared, Ibrahim S Sidibé, Fatimazahra Erregad, Nawal Hammas, Laila Chbani, Hinde El Fatemi
Background: Endometrial stromal sarcoma (ESS) is a rare neoplasm accounting for only 0.2% of female genital tract tumors. The primary extra-uterine location of ESS is an extremely uncommon occurrence. Case presentation: We present a case of a 64-year-old woman presenting with abdominopelvic and bilateral ovarian tumors with misleading clinical presentation and diagnostic challenge. The histopathological examination of the resected specimens disclosed the diagnosis of primary extra-uterine ESS arising from ovarian endometriosis...
2019: Gynecologic Oncology Research and Practice
https://read.qxmd.com/read/30715359/impact-of-unilateral-versus-bilateral-ovarian-endometriotic-cystectomy-on-ovarian-reserve-a-systematic-review-and-meta-analysis
#6
Johnny S Younis, Nora Shapso, Richard Fleming, Izhar Ben-Shlomo, Ido Izhaki
BACKGROUND: Ovarian endometrioma is a frequent manifestation of endometriosis in women of reproductive age. Several issues related to its space occupying effects, local reactions and surgical removal continue to be actively debated today. The impact of ovarian endometrioma per se on ovarian reserve is still controversial and the effect of ovarian surgery is still actively discussed. Furthermore, the optimal biomarker of ovarian reserve estimation in women with ovarian endometrioma is still under examination...
February 1, 2019: Human Reproduction Update
https://read.qxmd.com/read/30708269/the-association-between-ultrasound-based-soft-markers-and-endometriosis-type-location-a-prospective-observational-study
#7
Shannon Reid, Mathew Leonardi, Chuan Lu, George Condous
OBJECTIVE: Evaluate whether symptoms and/or transvaginal ultrasound (TVS) 'soft markers' (ovarian immobility and/or site-specific tenderness (SST)) are associated with endometriosis type/location. STUDY DESIGN: Multicenter prospective observational study (January 2009 to February 2013) in tertiary centers for women with chronic pelvic pain who underwent detailed history, specialized TVS, and laparoscopy. Chart findings were collated into a study database. Outcome measures included correlation between symptoms, ovarian immobility or SST on TVS and endometriosis type and/or location...
January 22, 2019: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/30708116/anatomic-cartography-of-the-hypogastric-nerves-and-surgical-insights-for-autonomic-preservation-during-radical-pelvic-procedures
#8
Prof Renato Seracchioli, Mohamed Mabrouk, Manuela Mastronardi, Diego Raimondo, Alessandro Arena, Simona Del Forno, Giulia Adalgisa Mariani, Prof Anna Maria Billi, Prof Lucia Manzoli, Prof W Michael O'Guin, Prof Nucelio Lemos
STUDY OBJECTIVE: To clarify the relationship of hypogastric nerves (HNs) with several pelvic anatomical landmarks and to assess any anatomical differences between the two sides of the pelvis, both in cadaveric and in vivo dissections. DESIGN: Prospective observational study (Canadian Task Force II-1). SETTING: Anatomical theatre for cadaveric dissections; University Hospital for in vivo laparoscopy. PATIENTS: Five nulliparous female cadavers underwent laparotomic dissection; ten nulliparous patients underwent laparoscopic surgery for rectosigmoid endometriosis without postero-lateral parametrial infiltration...
January 29, 2019: Journal of Minimally Invasive Gynecology
https://read.qxmd.com/read/30708067/surgical-management-of-superficial-peritoneal-adolescent-endometriosis
#9
Marc R Laufer, Jon I Einarsson
BACKGROUND: Adolescent endometriosis typically presents as Stage I with superficial peritoneal disease [SPD] and less commonly as Stage III or IV with deeply infiltrative disease [DIE]. Endometriosis lesions can be destroyed (cautery or laser), cutting out the discrete lesion with excision and destroyed, or radically excised with removal of the lesion and surrounding tissue. It has been shown to be beneficial to excise DIE to improve pain. Radical excision has been promoted by a subset of surgeons and involves removal of large areas of peritoneum with the promise/proposal of a cure and suggestion of no need for medical suppression of endometriosis...
January 29, 2019: Journal of Pediatric and Adolescent Gynecology
https://read.qxmd.com/read/30704956/-epithelial-ovarian-cancer-and-fertility-preservation-article-drafted-from-the-french-guidelines-in-oncology-entitled-initial-management-of-patients-with-epithelial-ovarian-cancer-developed-by-francogyn-cngof-sfog-gineco-arcagy-under-the-aegis-of-cngof-and
#10
C Uzan, B Courbiere, N Chabbert-Buffet
OBJECTIVES: To study the methods and strategies of fertility preservation in young women with stage I epithelial ovarian cancer (EOC), in order to provide recommendations for clinical practice. METHODS: The PubMed database was searched for english and french language articles, between 2005 and 2001, according to predefined search equations. RESULTS: Young patients with stage IA EOC willing to conceive should be informed that conservative treatment (contralateral ovary and salpinx, uterus) is possible (GradeC), associated with a 6 % to 13 % recurrence risk (GradeC) on the remaining ovary...
January 28, 2019: Gynecologie, Obstetrique, Fertilite & Senologie
https://read.qxmd.com/read/30697075/high-grade-endometrial-stromal-sarcoma-a-retrospective-study-of-factors-influencing-prognosis
#11
Yan-Yan Zhang, Yan Li, Meng Qin, Yan Cai, Ying Jin, Ling-Ya Pan
Objectives: The aim of this study was to evaluate the factors associated with progress-free survival (PFS) and overall survival (OS) in patients with high-grade endometrial stromal sarcoma (HG-ESS). Patients and methods: A total of 40 patients were enrolled in this study at the Peking Union Medical College Hospital, Beijing, China, from 2006 to 2016. The study retrospectively analyzed clinical and pathological data, and associations of these variables with PFS and OS were evaluated...
2019: Cancer Management and Research
https://read.qxmd.com/read/30691974/-endometriosis-assessment-of-the-ultrasound-based-endometriosis-staging-system-score-ubess-in-predicting-surgical-difficulty
#12
S Chaabane, H-T Nguyen Xuan, A Paternostre, J Du Cheyron, R Harizi, M Mimouni, A Fauconnier
OBJECTIVES: Surgical management of endometriosis may require different levels of surgical skill which influences the orientation of the patient. The Ultrasound-Based Endometriosis Staging System (UBESS) is a score developed in 2016 to predict the difficulty of surgery. To study the correlation between UBESS score and two main surgical classifications in the literature. METHODS: Study performed at the center of Poissy, France, between July 2016 and December 2017...
January 25, 2019: Gynecologie, Obstetrique, Fertilite & Senologie
https://read.qxmd.com/read/30689856/sensory-nerve-derived-neuropeptides-accelerate-the-development-and-fibrogenesis-of-endometriosis
#13
Xishi Liu, Dingmin Yan, Sun-Wei Guo
STUDY QUESTION: Do sensory nerves play any role in the development of endometriosis? SUMMARY ANSWER: Sensory nerves participate in all major steps (epithelial-mesenchymal transition (EMT), fibroblast-to-myofibroblast transdifferentiation (FMT) and smooth muscle metaplasia (SMM)) in the development and fibrogenesis of endometriotic lesions. WHAT IS KNOWN ALREADY: Endometriotic lesions are known to be hyperinnervated due to neurogenesis resulting from neutrophins secreted by endometriotic lesions and possibly platelets...
January 28, 2019: Human Reproduction
https://read.qxmd.com/read/30677178/hemoperitoneum-as-a-precursor-of-deep-pelvic-endometriosis-a-cohort-study
#14
E Bean, A Cutner, E Saridogan, M Wong, J Naftalin, D Jurkovic
OBJECTIVE: To determine whether significant hemoperitoneum could be a precursor of deep pelvic endometriosis METHODS: This was a prospective observational cohort study which was carried out in a dedicated gynecological diagnostic unit over a period of 18 months. We included consecutive pre-menopausal, non-pregnant women who attended with severe acute lower abdominal pain and underwent a pelvic ultrasound examination. Women were triaged for surgical or conservative management depending on the cause of pain and severity of their symptoms...
January 24, 2019: Ultrasound in Obstetrics & Gynecology
https://read.qxmd.com/read/30671391/clinicopathologic-characteristics-of-ovarian-clear-cell-carcinoma-in-the-background-of-endometrioma-a-surveillance-strategy-for-an-early-detection-of-malignant-transformation-in-patients-with-asymptomatic-endometrioma
#15
Joo-Hyuk Son, Seokyoung Yoon, Seokyung Kim, Tae-Wook Kong, Jiheum Paek, Suk-Joon Chang, Hee-Sug Ryu
Objective: This study aimed to analyze the clinical features of clear cell carcinoma in relation to endometriosis and to determine an appropriate surveillance strategy for the early detection of malignant transformation of endometrioma in asymptomatic patients. Methods: We retrospectively reviewed the clinicopathologic data of 50 patients with ovarian clear cell carcinoma. Clinicopathologic characteristics, treatment outcomes, and the association between endometriosis and the risk of malignant transformation were analyzed...
January 2019: Obstetrics & Gynecology Science
https://read.qxmd.com/read/30671388/could-surgical-management-improve-the-ivf-outcomes-in-infertile-women-with-endometrioma-a-review
#16
REVIEW
Hyun Jong Park, Hannah Kim, Geun Ho Lee, Tae Ki Yoon, Woo Sik Lee
Endometriosis is a chronic inflammatory condition that affects fertility and could be toxic to the ovary. Endometrioma per se and surgical interventions for endometrioma significantly reduce the ovarian reserve. Therefore, to prepare for surgical intervention for endometrioma, the high-risk group with decreased ovarian reserve must be considered. There is no evidence to support the use of surgical intervention before in vitro fertilization (IVF) to improve the reproductive outcomes of subsequent IVF in infertile women with advanced-stage endometriosis or endometrioma...
January 2019: Obstetrics & Gynecology Science
https://read.qxmd.com/read/30664383/hormonal-contraception-in-women-with-endometriosis-a-systematic-review
#17
Giovanni Grandi, Fabio Barra, Simone Ferrero, Filomena Giulia Sileo, Emma Bertucci, Antonella Napolitano, Fabio Facchinetti
OBJECTIVE: A systematic review was carried out of studies of women with endometriosis, to examine the evidence for efficacy of the use of hormonal contraception to improve disease-related pain and decrease postoperative risk of disease recurrence. METHODS: A search of the Medline/PubMed and Embase databases was performed to identify all published English language studies on hormonal contraceptive therapies (combined hormonal contraceptives [CHCs], combined oral contraceptives [COCs], progestin-only pills [POPs] and progestin-only contraceptives [POCs]) in women with a validated endometriosis diagnosis, in comparison with placebo, comparator therapies or other hormonal therapies...
January 21, 2019: European Journal of Contraception & Reproductive Health Care
https://read.qxmd.com/read/30662252/effect-of-anterior-compartment-endometriosis-excision-on-infertility
#18
Gabriele Centini, Karolina Afors, Joao Alves, István Máté Argay, Philippe R Koninckx, Lucia Lazzeri, Giorgia Monti, Errico Zupi, Arnaud Wattiez
Background and Objectives: Laparoscopic surgical excision of bladder nodules has been demonstrated to be effective in relieving associated painful symptoms; the data are lacking concerning the impact of anterior compartment endometriosis on infertility. We conducted this study to evaluate whether or not the surgical excision of deep endometriosis affecting the anterior compartment plays a role in restoring fertility. Methods: This multicentre, retrospective study included a group of 55 patients presenting with otherwise-unexplained infertility who had undergone laparoscopic excision of anterior compartment endometriosis with histological confirmation...
October 2018: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://read.qxmd.com/read/30658623/cesarean-scar-endometriosis-presentation-of-198-cases-and-literature-review
#19
Ping Zhang, Yabing Sun, Chen Zhang, Yeping Yang, Linna Zhang, Ningling Wang, Hong Xu
BACKGROUND: Cesarean scar endometriosis (CSE) is the most common type of abdominal wall endometriosis (AWE). The aim of this study was to systematically identify the clinical features of CSE and recommend precautionary measures. METHODS: A large, retrospective study was undertaken with CSE patients treated surgically at our hospital between January 2005 and December 2017. RESULTS: A total of 198 CSE patients were enrolled, with a mean age of 32...
January 18, 2019: BMC Women's Health
https://read.qxmd.com/read/30643859/recurrent-abdominal-wall-endometriosis-at-the-trocar-site-of-laparoscopy-a-rare-case
#20
Mojgan Akbarzadeh-Jahromi, Maedeh Motavas, Afsoon Fazelzadeh
Background: Surgical scar endometriosis is typically presented as a slow-growing, painful abdominal mass near the site of a past surgery. Endometriosis on the trocar port site is rare. To best of our knowledge, only 17 cases have been reported in the literature. The nonspecific nature of endometriosis presents a diagnostic challenge, and it is often considered as an incisional hernia or other conditions. Case: Here, we described our experience with a recurrent abdominal scar endometriosis case at the trocar port site of a previous laparoscopy, which was initially thought to be an incisional hernia...
October 2018: International Journal of Reproductive Biomedicine (Yazd, Iran)
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