keyword
https://read.qxmd.com/read/38512920/mortality-in-patients-with-normal-left-ventricular-function-requiring-emergency-va-ecmo-for-postcardiotomy-cardiogenic-shock-due-to-coronary-malperfusion
#21
JOURNAL ARTICLE
Jagdip Kang, Mateo Marin-Cuartas, Anna Flo Forner, Priya R Menon, André Ginther, Diyar Saaed, Suzanne de Waha, Massimiliano Meineri, Jörg Ender, Michael A Borger
OBJECTIVES: To analyze outcomes in patients with normal preoperative left ventricular ejection fraction (LVEF) undergoing venoarterial extracorporeal membrane oxygenation (VA-ECMO) therapy due to postcardiotomy cardiogenic shock (PCCS) related to coronary malperfusion. METHODS: Retrospective single-center analysis in patients with normal preoperative LVEF treated with VA-ECMO for coronary malperfusion-related PCCS between May 1998 and May 2018. The primary outcome was 30-day mortality, which was compared using the Kaplan-Meier method and the log-rank test...
2024: PloS One
https://read.qxmd.com/read/38510924/underutilization-of-left-heart-catheterization-in-kidney-transplant-patients-presenting-with-non-st-segment-elevation-myocardial-infarction
#22
JOURNAL ARTICLE
Ahmad Mustafa, Samer Asmar, Chapman Wei, John Afif, Shahkar Khan, Taqi Rizvi, Radu Grovu, Mitchell Weinberg, Suzanne El-Sayegh
BACKGROUND: Cardiovascular disease (CVD) is the leading cause of mortality in kidney transplant (KT) patients. The perceived risk of contrast-induced nephropathy (CIN) may create a reluctance to perform coronary angiography in patients presenting with non-ST segment elevation myocardial infarction (NSTEMI). METHODS: National Inpatient Sample (NIS) Database was used to sample individuals presenting with NSTEMI. Patients were stratified into KT and Non-KT cohorts...
June 2023: American heart journal plus: cardiology research and practice
https://read.qxmd.com/read/38510775/the-use-of-sustained-low-efficiency-dialysis-in-the-treatment-of-sepsis-associated-acute-kidney-injury-in-a-low-income-country-a-prospective-cohort-study
#23
JOURNAL ARTICLE
Abdalla Kamal Abdalla Taha, Mazin Mohammed Taha Shigidi, Nazik Mahmoud Abdulfatah, Rajabia Khidir Alsayed
BACKGROUND: Limited data are available regarding the management and outcomes of patients with sepsis-associated acute kidney injury (SA-AKI) requiring dialysis in Sudan. Continuous renal replacement therapy (CRRT) is a highly favored treatment modality in such patients. However, it stays unavailable and expensive treatment in most low-income countries. We aimed to evaluate the use of sustained low-efficiency dialysis (SLED) in the treatment of hemodynamically unstable patients with SA-AKI admitted to the intensive care unit (ICU)...
January 2024: Indian Journal of Critical Care Medicine
https://read.qxmd.com/read/38510762/acute-kidney-injury-in-patients-undergoing-extracorporeal-membrane-oxygenation-a-retrospective-cohort-study
#24
JOURNAL ARTICLE
Aswin Surjit, Bipi Prasannan, Jobin Abraham, Anuroop Balagopal, Vavullipathy Narayanan Unni
AIMS AND BACKGROUND: Extracorporeal membrane oxygenation (ECMO) is a mode of extracorporeal therapy to support oxygenation of patients with severe cardiac or respiratory failure. Studies have shown that acute kidney injury (AKI) can worsen the outcome in these patients. This study aims to assess the incidence and outcome of AKI in patients on ECMO support. MATERIALS AND METHODS: This retrospective study included 64 patients who underwent ECMO for more than 24 hours...
January 2024: Indian Journal of Critical Care Medicine
https://read.qxmd.com/read/38509493/analysis-of-the-incidence-and-risk-factors-of-blood-transfusion-in-total-knee-revision-a-retrospective-nationwide-inpatient-sample-database-study
#25
JOURNAL ARTICLE
Xiaoyin Li, Hao Xie, Shuxia Liu, Jian Wang, Zhanjun Shi, Qiaobing Yao, Qinfeng Yang, Qiuhong Li, Liangxiao Bao
OBJECTIVE: This study sought to determine the incidence and risk factors of blood transfusion among patients undergoing total knee revision (TKR) using a nationwide database. METHODS: A retrospective data analysis was conducted based on the Nationwide Inpatient Sample (NIS), enrolling patients who underwent TKR from 2010 to 2019 with complete information. The patients were divided into two groups based on whether they received blood transfusion or not. The demographic characteristics (race, sex, and age), length of stay (LOS), total charge of hospitalization, hospital characteristics (admission type, insurance type, bed size, teaching status, location, and region of hospital), hospital mortality, comorbidities, and perioperative complications were analyzed...
March 20, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38509341/effectiveness-and-safety-of-empagliflozin-final-results-from-the-emprise-study
#26
JOURNAL ARTICLE
Phyo T Htoo, Helen Tesfaye, Sebastian Schneeweiss, Deborah J Wexler, Brendan M Everett, Robert J Glynn, Niklas Schmedt, Lisette Koeneman, Anouk Déruaz-Luyet, Julie M Paik, Elisabetta Patorno
AIMS/HYPOTHESIS: Limited evidence exists on the comparative safety and effectiveness of empagliflozin against alternative glucose-lowering medications in individuals with type 2 diabetes with the broad spectrum of cardiovascular risk. The EMPagliflozin compaRative effectIveness and SafEty (EMPRISE) cohort study was designed to monitor the safety and effectiveness of empagliflozin periodically for a period of 5 years with data collection from electronic healthcare databases. METHODS: We identified individuals ≥18 years old with type 2 diabetes who initiated empagliflozin or dipeptidyl peptidase-4 inhibitors (DPP-4i) from 2014 to 2019 using US Medicare and commercial claims databases...
March 21, 2024: Diabetologia
https://read.qxmd.com/read/38508995/spontaneous-rupture-of-bladder-diverticulum-with-pseudo-renal-failure-a-case-report-and-literature-review
#27
Zhuo Zhang, Jing Shen, Qian He, Hu Nie
BACKGROUND: Spontaneous or non-traumatic bladder rupture is rare but can be life-threatening. Bladder rupture caused by a diverticulum is extremely rare, with only a few case reports in medical literature. CASE PRESENTATION: We report the case of a 32-year-old woman admitted to hospital complaints of abdominal pain, oliguria and ascites with no history of trauma. Laboratory tests revealed an elevated serum urea nitrogen(UN) level of 33.5 mmol/l and an elevated creatinine levels of 528 umol/l...
March 16, 2024: American Journal of Emergency Medicine
https://read.qxmd.com/read/38508445/the-evaluation-of-outcomes-after-thoracic-endovascular-aortic-repair-for-type-b-aortic-dissection-in-mainland-china
#28
REVIEW
Heyue Jia, Pengfei Yuan, Shanshan Wu, Rui Yang, Hai-Lei Li, Wei Guo, Duanduan Chen, Jiang Xiong
OBJECTIVE: To assess the mortality and outcomes following thoracic endovascular aortic repair (TEVAR) in patients with type B aortic dissection (TBAD) in mainland China, and to compare these outcomes with data from Western countries, while analyzing the potential reasons for differences among different countries. METHODS: An extensive literature search spanning from January 1999 to October 2023 was conducted using PubMed, Cochrane Library, and Embase databases for studies on endovascular treatment for TBAD...
March 18, 2024: Annals of Vascular Surgery
https://read.qxmd.com/read/38507056/short-and-long-term-outcomes-of-patients-with-active-cancer-presenting-with-an-acute-coronary-syndrome
#29
JOURNAL ARTICLE
Inbar Nardi Agmon, Ori Rahat, Roy Beigel, Tal Ovdat, Manhal Habib, Oran Tzuman, Limor Ilan Bushari, Ran Kornowski, Katia Orvin
BACKGROUND: Management of cancer patients presenting with an acute coronary syndrome (ACS) may be challenging. In this study, we sought to examine whether and how a concomitant diagnosis of active cancer affects patients' management and outcomes following an event of ACS. METHODS: We used a retrospective cohort data analysis of patients from the Acute Coronary Syndrome Israeli Survey (ACSIS) carried out between the years 2016-2021 to compare patients with and without a concomitant diagnosis of active cancer...
March 20, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38505790/decoding-hepatorenal-tyrosinemia-type-1-unraveling-the-impact-of-early-detection-ntbc-and-the-role-of-liver-transplantation
#30
REVIEW
Mohit Kehar, Moinak Sen Sarma, Jayendra Seetharaman, Carolina Jimenez Rivera, Pranesh Chakraborty
Hepatorenal tyrosinemia type 1 (HT-1) is a rare autosomal recessive disease that results from a deficiency of fumaryl acetoacetate hydrolase (FAH), a critical enzyme in the catabolic pathway for tyrosine. This leads to the accumulation of toxic metabolites such as fumaryl and maleylacetoacetate, which can damage the liver, kidneys, and nervous system. The discovery of 2-[2-nitro-4-trifluoromethylbenzoyl]-1,3-cyclohexanedione (NTBC or nitisinone) has significantly improved the management of HT-1, particularly when initiated before the onset of symptoms...
February 2024: Canadian liver journal
https://read.qxmd.com/read/38505248/hepatitis-e-virus-hev-infection-among-immunocompromised-individuals-a-brief-narrative-review
#31
REVIEW
Radostina Alexandrova, Ilia Tsachev, Plamen Kirov, Abedulkadir Abudalleh, Hristo Hristov, Tanya Zhivkova, Lora Dyakova, Magdalena Baymakova
Hepatitis E virus (HEV) is a single-stranded positive-sense RNA virus that belongs to Hepeviridae family. HEV is the most common cause of acute viral hepatitis worldwide. According to the World Health Organization (WHO), there are estimated 20 million HEV infections worldwide every year, leading to estimated 3.3 million symptomatic cases of HEV infection. The WHO estimates that HEV infection caused approximately 44,000 deaths in 2015, which represents 3.3% of mortality rates due to viral hepatitis. In low-income (LI) countries and lower-middle-income (LMI) countries, HEV is a waterborne infection induced by HEV genotype (gt) 1 and HEV gt 2 that cause large outbreaks and affect young individuals with a high mortality rate in pregnant women from South Asian countries and patients with liver diseases...
2024: Infection and Drug Resistance
https://read.qxmd.com/read/38505014/more-attention-should-be-paid-to-omicron-associated-sepsis-a-multicenter-retrospective-study-in-south-china
#32
JOURNAL ARTICLE
Ling Sang, Yonghao Xu, Yongbo Huang, Zhengtu Li, Deliang Wen, Changbo Liu, Yichun Wang, Lewu Xian, Linling Cheng, Feng Ye, Hongkai Wu, Xilong Deng, Yueping Li, Weiyan Ye, Nanshan Zhong, Yimin Li, Shiyue Li, Xiaoqing Liu
BACKGROUND: The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly transmissible but causes less severe disease compared to other variants. However, its association with sepsis incidence and outcomes is unclear. This study aimed to investigate the incidence of Omicron-associated sepsis, as per the Sepsis 3.0 definition, in hospitalized patients, and to explore its relationship with clinical characteristics and prognosis. METHODS: This multicenter retrospective study included adults hospitalized with confirmed SARS-CoV-2 infection across six tertiary hospitals in Guangzhou, China from November 2022 to January 2023...
February 29, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38504911/post-operative-sepsis-induced-acute-respiratory-distress-syndrome-risk-factors-for-a-life-threatening-complication
#33
JOURNAL ARTICLE
Miguel Bardají-Carrillo, Marta Martín-Fernández, Rocío López-Herrero, Juan Manuel Priede-Vimbela, María Heredia-Rodríguez, Esther Gómez-Sánchez, Estefanía Gómez-Pesquera, Mario Lorenzo-López, Pablo Jorge-Monjas, Rodrigo Poves-Álvarez, Jesús Villar, Eduardo Tamayo
INTRODUCTION: Prevalence and mortality of the acute respiratory distress syndrome (ARDS) in intensive care units (ICU) are unacceptably high. There is scarce literature on post-operative sepsis-induced ARDS despite that sepsis and major surgery are conditions associated with ARDS. We aimed to examine the impact of post-operative sepsis-induced ARDS on 60-day mortality. METHODS: We performed a secondary analysis of a prospective observational study in 454 patients who underwent major surgery admitted into a single ICU...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38503767/renal-biopsies-from-donors-with-acute-kidney-injury-show-different-molecular-patterns-according-to-the-post-transplant-function
#34
JOURNAL ARTICLE
Flavia Neri, Maria Letizia Lo Faro, Maria Kaisar, Ka Ho Tam, Martyna Borak, Jan Lindeman, Annalisa Angelini, Marny Fedrigo, Jesper Kers, James Hunter, Rutger Ploeg
The utilization of kidneys from donors with acute kidney injury (AKI) is often limited by unpredictable post-transplantation outcomes. The aim of our study was to identify protein mediators implicated in either recovery or failure of these organs. Forty kidney biopsies from donors with (20) and without AKI (20) were selected and then subdivided according to the post-transplant outcome defined as a threshold of 45 ml/min for the eGFR at 1 year from transplantation. Tissue homogenates were analysed by western blot to assess how the levels of 17 pre-selected proteins varied across the four groups...
March 19, 2024: Scientific Reports
https://read.qxmd.com/read/38502003/persistent-hypernatremia-secondary-to-adipsic-central-diabetes-insipidus-in-a-patient-with-herpes-induced-meningoencephalitis-and-covid-19-infection-a-case-report
#35
JOURNAL ARTICLE
Faten Cherchir, Ibtissem Oueslati, Salma Salhi, Asma Ben Hamida, Meriem Yazidi, Melika Chihaoui
Central diabetes insipidus (CDI) typically manifests as a polyuria-polydipsia syndrome, in which normonatremia is generally maintained through the polydipsia. A 53-year-old woman presented with diabetic ketosis and hyperosmolar hyperglycemic syndrome. Her medical history included herpes meningoencephalitis, which was associated with confusion and amnesia. On physical examination, she was apyretic, confused, and had signs of extracellular dehydration. Her capillary glucose concentration was high and her urine was positive for ketones...
March 2024: Journal of International Medical Research
https://read.qxmd.com/read/38501167/reviving-decades-old-wisdom-longitudinal-analysis-of-renin-angiotensin-system-inhibitors-and-its-effects-on-acute-ischemic-stroke-to-improve-outcomes
#36
JOURNAL ARTICLE
Sophie Samuel, Kyndol Craver, Charles Miller, Brittany Pelsue, Catherine Gonzalez, Teresa A Allison, Brian Gulbis, H Alex Choi, Seokhun Kim
BACKGROUND: While Renin-Angiotensin System (RAS) inhibitors have a longstanding history in blood pressure control, their suitability as first-line in-patient treatment may be limited due to prolonged half-life and kidney failure concerns. METHODS: Using a cohort design, we assessed the impact of RAS inhibitors, either alone or in combination with beta-blockers, on mortality, while exploring interactions, including those related to end-stage renal disease and serum creatinine levels...
March 19, 2024: American Journal of Hypertension
https://read.qxmd.com/read/38500867/acute-liver-injury-and-contralateral-pleural-effusion-as-two-rare-complications-following-percutaneous-nephrolithotomy-a-case-report
#37
Reza Kazemi, Faezeh Jandaghi, Farzaneh Montazeri, Hanieh Salehi
INTRODUCTION: Percutaneous Nephrolithotomy (PCNL) is a widely used surgical intervention for removing large and complex renal calculi. While considered a safe and effective procedure, it can still lead to severe and rare complications, including bleeding, pulmonary complications, and liver dysfunction. CASE PRESENTATION: This case report presents a case who underwent PCNL for a kidney stone and subsequently developed a series of rare and severe complications. Following the PCNL procedure, the patient experienced significant bleeding, a known but uncommon complication of PCNL, pulmonary complications, a common complication that may carry a risk of death, and acute liver failure, an exceedingly rare consequence of PCNL...
2024: American Journal of Clinical and Experimental Urology
https://read.qxmd.com/read/38500492/transient-acute-kidney-injury-after-chimeric-antigen-receptor-t-cell-therapy-in-patients-with-hematological-malignancies
#38
JOURNAL ARTICLE
Juan León-Román, Gloria Iacoboni, Sheila Bermejo, Cecilia Carpio, Mónica Bolufer, Clara García-Carro, Mario Sánchez-Salinas, Carla Alonso-Martínez, Oriol Bestard, Pere Barba, María José Soler
BACKGROUND: Acute kidney injury (AKI) occurs in 30% of patients infused with chimeric antigen receptor (CAR) T-cells. The purpose of this study was to identify risk factors and long-term outcomes after AKI in patients who received CAR T-cell therapy. METHODS: Medical records of 115 adult patients with R/R hematological malignancies treated with CD19-targeted CAR T-cells at Vall d'Hebron University Hospital between July 2018 and May 2021. Baseline demographic data including age, gender, ethnicity, body mass index (BMI), and co-morbidities, as well as the type of hematological neoplasia and prior lines of therapy were collected...
March 2024: Clinical Kidney Journal
https://read.qxmd.com/read/38499459/plasma-exchange-for-the-management-of-digoxin-toxicity-in-an-individual-with-an-acute-kidney-injury-a-case-report
#39
JOURNAL ARTICLE
Hannah Preston, Emma Cannon, Simon Watson
Digoxin toxicity can be life-threatening. Digoxin-specific antibody (DSA) fragments are used in severe digoxin toxicity, binding to serum-free digoxin and enabling increased renal excretion. In severe renal impairment, clearance of these complexes is prolonged, leading to rebound toxicity. Digoxin and DSA complexes are not dialysable. We present a case of a gentleman with severe digoxin toxicity and acute kidney injury (AKI). Despite receiving DSA doses, his digoxin levels rebounded and symptoms persisted. Based on published case reports, plasma exchange (PEX) after further dosing was arranged...
March 18, 2024: Journal of the Royal College of Physicians of Edinburgh
https://read.qxmd.com/read/38499082/sex-differences-in-heart-transplantation-analysis-of-the-national-inpatient-sample-2012-2019
#40
REVIEW
Nakeya Dewaswala, Huzefa Bhopalwala, Abdul Mannan Khan Minhas, Khadija Amanullah, Dmitry Abramov, Samiullah Arshad, Sourbha Dani, Gaurang Vaidya, Dipanjan Banerjee, Emma Birks, Erin Michos
INTRODUCTION: Advanced heart failure therapies and heart transplantation (HT) have been underutilized in women. Therefore, we aimed to explore the clinical characteristics and outcomes of HT by sex. METHODS: We conducted a retrospective analysis of adult discharges from the National Inpatient Sample (NIS) between 2012 and 2019. International Classification of Disease (ICD) procedure codes were used to identify those who underwent HT. RESULTS: A total of 20,180 HT hospitalizations were identified from 2012-2019...
March 16, 2024: Current Problems in Cardiology
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