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Trans PRK

Riping Zhang, Lixia Sun, Jinyu Li, Antony Law, Vishal Jhanji, Mingzhi Zhang
PURPOSE: To compare the visual and refractive outcomes of transepithelial photorefractive keratectomy (Trans-PRK) and sub-Bowman femtosecond-assisted laser in situ keratomileusis (SBK). SETTING: University hospital. DESIGN: Retrospective, comparative study. METHODS: Two hundred forty patients with myopia and myopic astigmatism underwent SBK (n=157) or Trans-PRK (n=83). The main outcome measures included manifest spherical equivalent refraction (MRSE), logarithm of the minimum angle of resolution uncorrected visual acuity (UCVA), and best-corrected visual acuity (BCVA), which were evaluated at 1 and 3 months postoperatively...
July 30, 2018: Eye & Contact Lens
Diego De Ortueta, Samuel Arba-Mosquera, Thomas Magnago
PURPOSE: To evaluate the temperature rise of human cornea during trans-epithelial photorefractive keratectomy (trans-PRK) with a 750Hz excimer laser employing Intelligent Thermal Effect Control (ITEC) software. METHODS: In this observational case series, trans-PRK ablation was performed on 5 eyes of 3 patients using an aspheric profile of a 750Hz excimer laser system. A high-resolution infrared camera with a frame-rate of 350 images per second was used to determine the corneal surface temperature...
July 20, 2018: Journal of Optometry
Ikhyun Jun, David Sung Yong Kang, Samuel Arba-Mosquera, Jin Young Choi, Hyung Keun Lee, Eung Kweon Kim, Kyoung Yul Seo, Tae-Im Kim
BACKGROUND: To compare the clinical outcomes of wavefront-optimized (WFO) transepithelial photorefractive keratectomy (trans-PRK) and corneal wavefront-guided (CWFG) trans-PRK for myopic eyes with moderate to high astigmatism. METHODS: One hundred ninety-six eyes (196 patients) with moderate to high astigmatism (≥ 1.75 D) treated with WFO or CWFG trans-PRK (101 and 95 eyes, respectively) were retrospectively registered. Safety, efficacy, predictability, vector analysis, and corneal aberrations were compared between groups preoperatively and at 6 months postoperatively...
June 26, 2018: BMC Ophthalmology
Assaf Gershoni, Michael Mimouni, Eitan Livny, Irit Bahar
PURPOSE: The aim of the study was to examine the outcomes of transepithelial photorefractive keratectomy (Trans-PRK) and Femtosecond Laser-assisted in situ keratomileusis (Z-LASIK) for the correction of high myopia. METHODS: A retrospective cohort study design was used. The study group included 792 eyes with high-grade myopia (- 6.0 diopters or higher) or high-grade myopia with astigmatism that were treated with Z-LASIK or Trans-PRK in 2013 through 2014 in an optical outpatient clinic of a large private medical service...
March 12, 2018: International Ophthalmology
Zahra Ghiasi, Tracy Gray, Phat Tran, Richard Dubielzig, Chris Murphy, David L McCartney, Ted W Reid
Purpose: To determine whether topical Substance-P (SP) plus insulin-like growth factor-1 (IGF-1) can improve corneal healing after photorefractive surface ablation in a rabbit. Methods: After a 9.0-mm corneal de-epithelialization using a combination of chemical (18% alcohol) and mechanical debridement, excimer photorefractive surface ablation was performed bilaterally in eight rabbits (16 eyes) with an 8.0-mm ablation zone and 70-μm depth. The right eye was treated with SP (250 μg/mL) and IGF-1 (25 ng/mL) in hyaluronic acid, one drop twice a day, and the other eye treated with only hyaluronic acid...
January 2018: Translational Vision Science & Technology
Igor M Kornilovskiy, Elmar M Kasimov, Ayten I Sultanova, Alexander A Burtsev
AIM: To estimate the biomechanical effect of the laser-induced cross-linking resulting from photorefractive ablation of the cornea with riboflavin. METHODS: Excimer laser ablation studies were performed ex vivo (32 eyes of 16 rabbits) by phototherapeutic keratectomy (PTK) and in vivo (24 eyes of 12 rabbits) by transepithelial photorefractive keratectomy (TransPRK), with and without riboflavin saturation of the stroma. Then, we performed corneal optical coherence tomography on 36 eyes of 18 patients with varying degrees of myopia at different times after the TransPRK was performed with riboflavin saturation of the stroma...
2016: Clinical Ophthalmology
M A Stepanova, E N Arkhipova, Yu S Medvedeva, M Yu Karganov, E N Eskina
The method of laser correlation spectroscopy (LCS) was used for the examination of the subfractional compound of tear fluid in patients who have been using soft contact lens (SCL) for a long period and before and after the excimer laser correction with transepithelial photorefractive keratectomy (Trans PRK). Based on the analysis of biological material of 141 patients aged from 18 to 33 years old, we can conclude that prolonged usage of SCL leads to catabolic processes in surface of the anterior segment of the eye and, as a result, to changes in the qualitative composition of the tear fluid...
January 2014: Patologicheskaia Fiziologiia i èksperimental'naia Terapiia
Okkes Baz, Necip Kara, Ercument Bozkurt, Engin Bilge Ozgurhan, Alper Agca, Kemal Yuksel, Yavuz Ozpinar, Ahmet Demirok
AIM: To evaluate the results of three photorefractive keratectomy (PRK) procedures in the treatment of astigmatism. METHODS: In this retrospective comparative case series, 89 eyes of 50 patients who underwent PRK treatment for astigmatism were enrolled. The patients were divided into 3 groups based on the PRK procedure: Group 1: PRK without mitomycin-C (MMC) application, Group 2: PRK with MMC application, and Group 3: Trans-Photorefractive Keratectomy (T-PRK). The efficacy, safety, predictability, and complications of treatment were assessed at 1, 3 and 6 months after the treatment...
2013: International Journal of Ophthalmology
David P S O'Brart
The aim was to review the recently published literature on excimer laser surface ablation procedures, including photorefractive keratectomy (PRK), laser sub-epithelial keratomileusis (LASEK), microkeratome-assisted PRK (epi-LASIK) and trans-epithelial (laser-assisted) PRK, to help elucidate where and how surface ablation may best fit into current refractive surgical practice. The emphasis was on publications within the last three years and included systemic reviews, meta-analyses and randomised controlled trials...
January 2014: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
Anne Marie Tremaine, Arisa Ortiz, Laila Elkeeb, Minh Tran, Gerald Weinstein
BACKGROUND: Many patients with rosacea cannot tolerate extended treatment periods with topical agents because their skin sensitivity is often increased. OBJECTIVE: To determine the long-term efficacy and tolerability of a new moisturizing lotion for improving the signs and symptoms of mild-to-moderate rosacea. METHODS: In a 48-week, open-label study, a moisturizing lotion containing furfuryl tetrahydropyranyladenine as PRK-124 (0.125%, Pyratine-XR, Senetek PLC, Napa, CA) was applied twice daily by 18 subjects with mild-to-moderate rosacea...
June 2010: Journal of Drugs in Dermatology: JDD
Arisa Ortiz, Laila Elkeeb, Anne Truitt, Rasha Hindiyeh, Lisa Aquino, Minh Tran, Gerald Weinstein
BACKGROUND: Current treatments for acne rosacea are often associated with unsatisfactory outcomes and adverse effects. OBJECTIVE: To determine the efficacy and tolerability of a new moisturizing lotion for improving the clinical signs and symptoms of mild-to-moderate acne rosacea. METHODS: In a 12-week, open-label study, a moisturizing lotion containing furfuryl tetrahydropyranyladenine as PRK124 (0.125%, Pyratine-XR, Senetek PLC, Napa, CA) was applied twice daily to subjects with mild-to-moderate rosacea...
May 2009: Journal of Drugs in Dermatology: JDD
U Windhövel, B Bowien
Three transposon Tn5-induced mutants deficient in autotrophic CO2 fixation were isolated from a megaplasmid pHG1-cured strain of Alcaligenes eutrophus H16. Their phenotypes were initially characterized by their ability to form both key enzymes of the Calvin cycle, ribulose-1,5-bisphosphate carboxylase (Rubisco) and phosphoribulokinase (PRK). Since the transposon insertions were at different sites within the chromosomal cluster of cfx genes encoding Calvin cycle enzymes, the individual mutants showed different inactivation patterns for Rubisco and PRK synthesis...
1990: Archives of Microbiology
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