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Junya Mu, Xiaohui Liu, Shaohui Ma, Tao Chen, Xueying Ma, Peng Li, Dun Ding, Jixin Liu, Ming Zhang
Restless legs syndrome (RLS) is common in the end-stage renal disease (ESRD) population; however, their interrelationship remains largely unclear. In the current study, we aimed to investigate the brain structure variation in ESRD patients with RLS (ERSD-RLS) and its potential relation with the severity of RLS. Diffusion tensor imaging and T1-weighted imaging were obtained from 64 ERSD-RLS and 64 matched healthy controls. Voxel-based morphometry (VBM) analysis and tractography atlas-based analysis (TABS) were used to detect the alteration of gray matter (GM) volume and white matter (WM) microstructural characterization...
September 26, 2018: Brain Imaging and Behavior
Rafael Alves da Silva, Jardelina de Souza Todão, Fernando Luiz Kamitani, Antonio Eduardo Benedito Silva, Roberto José de Carvalho-Filho, Maria Lucia Cardoso Gomes Ferraz, Isabel Maria Vicente Guedes de Carvalho
New direct-acting antiviral (DAA) agents are in development or already approved for the treatment of chronic hepatitis C virus (HCV) infection. The effectiveness of these drugs is related to the previous existence of resistant variants. Certain clinical conditions can allow changes in immunological characteristics of the host and even modify genetic features of viral populations. The aim of this study was to perform HCV molecular characterization from samples of end-stage renal disease patients on hemodialysis (ESRD-HD)...
March 2018: Journal of Medical Virology
C Toppe, A Möllsten, S Schön, G Dahlquist
AIMS: The development of end-stage renal disease (ESRD) in Type 1 diabetes is multifactorial. Familial socio-economic factors may influence adherence to and understanding of diabetes treatment, and also general health behaviour. We investigate how parental and personal education level and exposure to low economic status, indicated by the need for income support, influence the development of ERSD caused by Type 1 diabetes. METHODS: Participants were retrieved from the nationwide Swedish Childhood Diabetes Registry, which was linked to the Swedish Renal Registry, to find people with ESRD caused by Type 1 diabetes, and to Statistic Sweden to retrieve longitudinal socio-economic data on participants and their parents...
May 2017: Diabetic Medicine: a Journal of the British Diabetic Association
Gabriele Röhrig, Maria Cristina Polidori, Katherine Rascher, Mathias Schaller, Thomas Benzing, Gero von Gersdorff
BACKGROUND: Patients with end-stage renal disease (ESRD) requiring hemodialysis are typically characterized by multimorbidity and increasingly by advanced age; however, there are few data on their geriatric needs. OBJECTIVE: The aim of the study was to evaluate the clinical characteristics of a large cohort of incident patients in ambulatory hemodialysis units with a particular focus on those aged over 80 years in Germany. METHODS: The electronic patient registry of the Board of Trustees (Kuratorium) for Dialysis and Kidney Transplantation (KfH) was searched for all patients who began hemodialysis in 1 of the 191 units between 2007 and 2013 and were 65 years and older...
January 2018: Zeitschrift Für Gerontologie und Geriatrie
Yu Pan, Song Jiang, Dandan Qiu, Jingsong Shi, Minlin Zhou, Yu An, Yongchun Ge, Honglang Xie, Zhihong Liu
AIMS: This study aimed to determine whether eGFRcre-cys and its slope could improve the prediction of the long-term renal outcome in patients with type 2 diabetic nephropathy (DN). METHODS: The cross-sectional and longitudinal analyses included 501 type 2DN patients from 2003 to 2009. GFR was estimated using either eGFRcre-cys or the serum creatinine-based equation (eGFRcre) or the cystatin C-based equation (eGFRcys), and was classified into 3 categories (≥90, 60-90, ≤60ml/min per 1...
November 2016: Journal of Diabetes and its Complications
Alexander Meyer, Katharina Schinz, Werner Lang, Axel Schmid, Susanne Regus, Ulrich Rother
BACKGROUND: Management of dialysis patients with critical limb ischemia (CLI) still represents a challenge to vascular medicine, whereas the effects of the pedal arch quality in these patients with predominant affection of the infrapopliteal vessels have rarely been evaluated. Therefore, our aim was to analyze the outcomes of infrapopliteal angioplasty in the setting of chronic renal failure (end-stage renal disease) and evaluate the influence of the pedal arch involvement on clinical success...
August 2016: Annals of Vascular Surgery
Francisco Gerardo Yanowsky-Escatell, Leonardo Pazarín-Villaseñor, Jorge Andrade-Sierra, Miguel Angel Zambrano-Velarde, Francisco Martin Preciado-Figueroa, Christian Jesús Santana-Arciniega, Rogelio Ignacio Galeno-Sánchez
INTRODUCTION: serum albumin the biomarker most frequently used as one of three biochemical criteria for diagnosis of protein energy wasting (PEW). However, as a nutritional parameter it's unreliable in chronic kidney disease (CKD). The subjective global assessment (SGA) has been recommended for nutritional evaluation and the PEW in CKD. OBJECTIVE: determine association between the levels of serum albumin and SGA in patients with end stage renal disease (ESRD) who started peritoneal dialysis (PD)...
December 1, 2015: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Hiroaki Shimmura, Masaharu Tsubokura, Shigeaki Kato, Junichi Akiyama, Shuhei Nomura, Jinichi Mori, Tetsuya Tanimoto, Koichiro Abe, Shuji Sakai, Hiroshi Kawaguchi, Michio Tokiwa
OBJECTIVE: To assess internal radiocontamination of patients with end-stage renal disease (ESRD) who were regularly taking haemodialysis (HD) and living in areas affected by the crippled Fukushima Daiichi nuclear plant after the Great East Japan earthquake on 11 March 2011. METHODS: Internal radiocontamination in 111 patients with ESRD regularly taking HD at Jyoban Hospital in Iwaki city, Fukushima from July 2012 to November 2012 was assessed with a whole body counter (WBC)...
2015: BMJ Open
Yan Liu, Hao Zhang, Ke Zhang, Jun Liu, Liuchan Zhou, Xiangping Liao, Jianzhao Cheng, Xiaohua Deng, Zhiming Xia
Continuous ambulatory peritoneal dialysis (CAPD) is recognized as an effective and economical therapy for end-stage renal disease (ESRD). However, the drop-out and mortality rates of this treatment remain high. The aim of the present study was to investigate the potential effects of metabolic status and personality on the prognosis of ESRD patients receiving CAPD. A total of 835 patients (455 men and 380 women) were enrolled in the cross-sectional survey. Analysis of variance and Spearman correlations were used to analyze variables in two groups of ESRD patients: group L (dialysis duration < 3 years) and group H (dialysis duration ≥ 3 years)...
2015: International Journal of Clinical and Experimental Medicine
Mykola Prodanchuk, Oleksii Makarov, Evegnii Pisarev, Boris Sheiman, Mykola Kulyzkiy
INTRODUCTION: Accumulation of trace elements occurs in conditions of decreased kidney function. In some conditions, increased trace elements can have toxic features. On the other hand, studies are showing that concentration of some trace elements could be decreased in ERSD patients as well. The most important factor affecting trace element concentration in ERSD patients is the degree of renal failure and the usage of replacement therapy. MATERIALS AND METHODS: We analyzed the trace elements' (boron, aluminum, vanadium, chromium, manganese, cobalt, nickel, copper, zinc, arsenic, selenium, rubidium, strontium, cadmium, cesium, barium and lead) concentration in the whole blood of 41 ESRD patients who were treated with hemodialysis and hemodiafiltration and also of 61 healthy blood donors...
2014: Central European Journal of Urology
Jen-Chieh Liao, Chung-Han Ho, Fu-Wen Liang, Jhi-Joung Wang, Kao-Chang Lin, Chung-Ching Chio, Jinn-Rung Kuo
PURPOSE: This study aimed to investigate the one-year mortality associations in hemodialysis patients who underwent neurosurgical intervention after traumatic brain injury (TBI) using a nationwide database in Taiwan. MATERIALS AND METHODS: An age- and gender-matched longitudinal cohort study of 4416 subjects, 1104 TBI patients with end-stage renal disease (ESRD) and 3312 TBI patients without ESRD, was conducted using the National Health Insurance Research Database in Taiwan between January 2000 and December 2007...
2014: PloS One
Cheng Li, Huan-Huan Su, Ying-Wei Qiu, Xiao-Fei Lv, Sheng Shen, Wen-Feng Zhan, Jun-Zhang Tian, Gui-Hua Jiang
OBJECTIVE: To prospectively investigate and detect early cerebral regional homogeneity (ReHo) changes in neurologically asymptomatic patients with end stage renal disease (ESRD) using in vivo resting-state functional MR imaging (Rs-fMRI). METHODS: We enrolled 20 patients (15 men, 5 women; meanage, 37.1 years; range, 19-49 years) with ESRD and 20 healthy controls (15 men, 5 women; mean age, 38.3 years; range, 28-49 years). The mean duration of hemodialysis for the patient group was 10...
2014: PloS One
Shuo-Meng Wang, Ming-Nan Lai, Pau-Chung Chen, Jung-Der Wang
BACKGROUND/PURPOSE: End-stage renal disease (ESRD) may increase the likelihood of malignancy. The aim of this study is to evaluate the characteristics of increased urothelial cancer (UC) risk in patients with ESRD in Taiwan by a population-based study. METHODS: The standardized incidence ratios (SIRs) for UC among a registered cohort of ESRD in Taiwan during 1997-2002 were calculated using reimbursement data obtained from the Bureau of National Health Insurance (NHI), with the incidence rates of UC in the general population as the reference...
January 2015: Journal of the Formosan Medical Association
Anabela P Coelho, Helena O Sá, José A Diniz, Gilles Dussault
Portugal was the first European country to introduce an integrated management of end-stage renal disease (IM ESRD). This new program integrates various dialysis services and products, which are reimbursed at a fixed rate/patient/week called "comprehensive price payment." This initiative restructured the delivery of dialysis services, the monitoring of outcomes, and the funding of renal replacement therapy. This article described the implementation of a new model of comprehensive provision of hemodialysis (HD) services and aimed to assess its impact on dialysis care...
January 2014: Hemodialysis International
V A Goriaĭnov, M M Kaabak, L A Shishlo, N N Babenko, M M Morozova
The study aimed the estimation of posttransplantant anemia (PTA) frequency between the recepients of allogenic kidneys and testing the influence of different factors on the anemia development. The study was ased on the analysis of 129 patients with ERSD, to whom 129 donor kidneys were grafted. An actuarial survival of patients and allografts were calculated. The analysis demonstrated that a duration of the pretranplant hemodialysis influences the dynamics of hemoglobin level and the red blood cells count. The shorter were the dialysis terms, the easier was the anemia to correct...
2011: Khirurgiia
Akio Yamada, Norishi Ueda
It remains elusive what factors affect posterior reversible encephalopathy syndrome (PRES). Eleven PRES children, all with acute glomerulonephritis, Alport syndrome, and lupus nephritis, 5 with nephrosis, and 3 renal transplant recipients, were studied. PRES recurred in 1 patient. Neurological symptoms were graded as 1: mild (headache, nausea/vomiting, or tremor), 2: moderate (vision change), and 3: severe (mental dysfunction, cerebellar symptoms, seizures, recurrence of seizures, and coma). Magnetic resonance imaging was graded as 1: subtle change, 2: abnormal large areas, and 3: complete involvement of the regions...
February 2012: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
Jérôme Harambat, Karlijn J van Stralen, Jon Jin Kim, E Jane Tizard
In the past 30 years there have been major improvements in the care of children with chronic kidney disease (CKD). However, most of the available epidemiological data stem from end-stage renal disease (ESRD) registries and information on the earlier stages of pediatric CKD is still limited. The median reported incidence of renal replacement therapy (RRT) in children aged 0-19 years across the world in 2008 was 9 (range: 4-18) [corrected] per million of the age-related population). [corrected] The prevalence of RRT in 2008 ranged from 18 to 100 per million of the age-related population...
March 2012: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
Elaine Leandro Machado, Mariângela Leal Cherchiglia, Francisco de Assis Acúrcio
This is an observational, follow up study in order to characterize the patients profile in waiting list to kidney transplantation between 01/01/2000 and 12/31/2004 in Belo Horizonte (MG, Brazil) and their outcome in 12/31/2005. Sociodemographic and clinical characteristics of patients residents in Belo Horizonte city, 18 years of age or older was collected from State Transplantations Center of MG. Health professionals involved with transplantations answered to interviews to describe access barriers to it. Descriptive and comparative statistical analyses were performed with secondary data and qualitative analyses of the interviews were made...
March 2011: Ciência & Saúde Coletiva
T Hirano, K Nohtomi, N Nakanishi, T Watanabe, T Hyodo, T Taira
AIM: The aim of this study was to investigate the effects of ezetimibe on high-density lipoprotein (HDL) subspecies and serum amyloid A (SAA), an apolipoprotein mainly bound and transported by HDL particles, in patients with end-stage renal disease (ERSD), a condition typically characterized by high SAA- and low HDL-cholesterol (C ) levels. METHODS: 26 ERSD patients receiving hemodialysis (HD) were given ezetimibe (10 mg/d) for 6 - 8 weeks. HDL3 was separated from serum by a single precipitation method established by our group...
October 2010: Clinical Nephrology
A A Pawar, J Rathod, S Chaudhury, S K Saxena, D Saldanha, V S S R Ryali, K Srivastava
BACKGROUND: Recent studies have shown a high prevalence of depression and cognitive changes in patients with end-stage renal disease (ERSD) and renal transplant recipients. There are few data available on the cognitive and emotional changes in patients undergoing renal transplantation in India. AIM: To evaluate the changes in cognitive profile and depression in renal transplant recipients. METHODS: Thirty consecutive patients undergoing renal transplantation were evaluated 1 month before and 3 months after successful renal transplant with Beck Depression Inventory (BDI), Weschler Adult Performance Intelligence Scale (WAPIS), Luria Nebraska Neuropsychological battery (LNNB) and Life satisfaction scale...
January 2006: Indian Journal of Psychiatry
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