Na Zhang, Ayşe Baran, Ferzane Valioglu, Lei Teng, Mehmet Nuri Atalar, Cumali Keskin, Xiao-Xiong Wang, Abdulkerim Hatipoğlu, Mehmet Fırat Baran, Amine Hafis Abdelsalam, Sevki Arslan, Adem Necip, Musa Karadağ, Mehmet Hakkı Alma, Aziz Eftekhari, Aferin Beilerli
Verbascum thapsus (VT) is a medicinal plant that is used in folk medicine to treat a variety of ailments. For this study, the biological functions of VT methanol extract were determined in vitro. The plant's methanol extract was created through the maceration process. The phytochemical composition of plant extracts was investigated using liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS). The antioxidant capacity of the extract was determined using the DPPH (2,2-diphenyl-1-picrylhydrazil) and ABTS (2,2-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) tests and its cytotoxicity was assessed using the MTT ((3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, a tetrazole)) assay on the Caco-2 (human colorectal adenocarcinoma cells), LNCaP (Lymph Node Carcinoma of the Prostate), and HEK293 cell lines (Human embryonic kidney 293 cells) used to model colon, prostate, and non-cancerous cells...
December 20, 2023: Cellular and Molecular Biology