Olga Yu Shagaleeva, Daria A Kashatnikova, Dmitry A Kardonsky, Elena Yu Danilova, Viktor A Ivanov, Suleiman S Evsiev, Eugene A Zubkov, Olga V Abramova, Yana A Zorkina, Anna Y Morozova, Dmitry N Konanov, Artemiy S Silantiev, Boris A Efimov, Irina V Kolesnikova, Julia A Bespyatykh, Joanna Stimpson, Natalya B Zakharzhevskaya
Inflammatory bowel diseases are extremely common throughout the world. However, in most cases, it is asymptomatic at the initial stage. Therefore, it is important to develop non-invasive diagnostic methods that allow identification of the IBD risks in a timely manner. It is well known that gastrointestinal microbiota secrete volatile compounds (VOCs) and their composition may change in IBD. We propose a non-invasive method to identify the dynamics of IBD development in the acute and remission stage at the level of VOCs in model of dextran sulfate sodium (DSS) with chemically induced colitis measured by headspace GC/MS (HS GC/MS)...
March 14, 2024: International Journal of Molecular Sciences