keyword
Keywords thrombolysis in acute myocardi...

thrombolysis in acute myocardial infarction

https://read.qxmd.com/read/38498019/using-principles-of-digital-development-for-a-smartphone-app-to-support-data-collection-in-patients-with-acute-myocardial-infarction-and-physical-activity-intolerance-case-study
#1
JOURNAL ARTICLE
Diana Isabel Cáceres Rivera, Luz Mileyde Jaimes Rojas, Lyda Z Rojas, Diana Canon Gomez, David Andrés Castro Ruiz, Luis Alberto López Romero
BACKGROUND: Advances in health have highlighted the need to implement technologies as a fundamental part of the diagnosis, treatment, and recovery of patients at risk of or with health alterations. For this purpose, digital platforms have demonstrated their applicability in the identification of care needs. Nursing is a fundamental component in the care of patients with cardiovascular disorders and plays a crucial role in diagnosing human responses to these health conditions. Consequently, the validation of nursing diagnoses through ongoing research processes has become a necessity that can significantly impact both patients and health care professionals...
March 18, 2024: JMIR Formative Research
https://read.qxmd.com/read/38487882/no-reflow-prediction-in-acute-coronary-syndrome-during-percutaneous-coronary-intervention-the-norpacs-risk-score
#2
JOURNAL ARTICLE
Luke P Dawson, Muhammad Rashid, Diem T Dinh, Angela Brennan, Jason E Bloom, Sinjini Biswas, Jeffrey Lefkovits, James A Shaw, William Chan, David J Clark, Ernesto Oqueli, Chin Hiew, Melanie Freeman, Andrew J Taylor, Christopher M Reid, Andrew E Ajani, David M Kaye, Mamas A Mamas, Dion Stub
BACKGROUND: Suboptimal coronary reperfusion (no reflow) is common in acute coronary syndrome percutaneous coronary intervention (PCI) and is associated with poor outcomes. We aimed to develop and externally validate a clinical risk score for angiographic no reflow for use following angiography and before PCI. METHODS: We developed and externally validated a logistic regression model for prediction of no reflow among adult patients undergoing PCI for acute coronary syndrome using data from the Melbourne Interventional Group PCI registry (2005-2020; development cohort) and the British Cardiovascular Interventional Society PCI registry (2006-2020; external validation cohort)...
March 15, 2024: Circulation. Cardiovascular Interventions
https://read.qxmd.com/read/38460169/risk-factors-for-electrical-storms-following-percutaneous-coronary-intervention-in-patients-with-acute-myocardial-infarction-a-meta-analysis
#3
Xiao Xiong, Qiang Ye, Yongquan Peng
Electrical storms (ESs) following percutaneous coronary intervention (PCI) in acute myocardial infarction (AMI) patients pose a significant challenge, affecting prognostic outcomes and increasing mortality. This meta-analysis synthesized data from 11 studies involving 9,666 AMI patients to identify risk factors associated with ES following PCI. Our findings revealed an average ES incidence of 7.70%, with identified risk factors including low thrombolysis in myocardial infarction (TIMI) flow grades (0-1), elevated cardiac troponin I levels, persistent hypotension, reperfusion arrhythmias, the right coronary artery being the infarct-related artery, increased diameter of the infarct-related artery, renal dysfunction, elevated creatine kinase-MB, and bradycardia...
March 7, 2024: Biomol Biomed
https://read.qxmd.com/read/38411246/age-shock-index-as-an-early-predictor-of-cardiovascular-death-in-acute-coronary-syndrome-patients
#4
JOURNAL ARTICLE
Pedro Rocha Carvalho, Marta Catarina Bernardo, Catarina Ribeiro Carvalho, Isabel Moreira, Sara Borges, José Pedro Guimarães, Fernando Fonseca Gonçalves, Pedro Mateus, José Paulo Fontes, Ilídio Moreira
BACKGROUND: The shock index (SI), reflecting heart rate (HR) to SBP ratio, is established for predicting adverse outcomes in acute coronary syndrome (ACS) patients. Exploring the age shock index (ASI), obtained by multiplying SI with age, could offer further insights into ACS prognosis. OBJECTIVES: Assess ASI's effectiveness in predicting in-hospital death in individuals with ACS. METHODS: This study encompassed patients with acute myocardial infarction, drawn from a national registry spanning October 2010 to January 2022...
February 20, 2024: Coronary Artery Disease
https://read.qxmd.com/read/38407428/correlation-of-osteopontin-hormone-with-timi-score-and-cardiac-markers-in-patients-with-acute-coronary-syndrome-presenting-with-chest-pain
#5
JOURNAL ARTICLE
Ayşe Şule Akan, Ibrahim Özlü
AIM: Rapid evaluation of patients with acute coronary syndrome (ACS) attending the emergency service under emergency room conditions and using appropriate risk scoring would improve treatment success. Calcium levels accumulate in the tissue in people with coronary artery disease and this has been found to correlate with osteopontin levels in some studies. It is predicted that osteopontin level could be used as a biomarker to detect coronary artery calcification. In this study, we aimed to evaluate the use of osteopontin levels in the differential diagnosis of ACS in conjunction with cardiac troponin I (cTnI) levels, and HEART (history, ECG, age, risk factors, troponin) and thrombolysis in myocardial infarction (TIMI) scores in patients with chest pain who attended the emergency service...
February 16, 2024: Cardiovascular Journal of Africa
https://read.qxmd.com/read/38390794/presence-of-residual-cardiac-thrombus-predicts-poor-outcome-in-cardioembolic-stroke-after-reperfusion-therapy
#6
JOURNAL ARTICLE
Tingxia Zhang, Huan Zhou, Jiansheng Yang, Ying Zhou, Yi Chen, Yaode He, Rui Xue, Zhicai Chen, Min Lou, Shenqiang Yan
BACKGROUND: In patients with acute cardiogenic cerebral embolism, a residual thrombus may still be present in the cardiac cavity even after reperfusion therapy. We aimed to investigate the occurrence of a residual cardiac thrombus in cardioembolic stroke after reperfusion therapy and analyze its impact on clinical outcome. METHODS AND RESULTS: We enrolled patients with cardioembolic stroke from our prospectively collected database who underwent 2-phase cardiac computed tomography within 7 days after reperfusion therapy...
February 23, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38382475/the-role-of-neurohospitalism-in-a-specialized-cardiovascular-hospital
#7
JOURNAL ARTICLE
Miguel Serôdio, Marta Magriço, André Sobral-Pinho, Rita Ventura, Filipa Serrazina, Gonçalo Cabral, Bruna Meira, Marco Fernandes, Manuel Salavisa, Marlene Saraiva, João Pedro Marto, Francisca Sá, Sofia Calado, Miguel Viana Baptista
INTRODUCTION: Cardiology and cardiothoracic surgery are among the specialties that most commonly require neurology inpatient consultations. We aimed to study the neurology referrals by the cardiovascular-specialized hospital included in our tertiary hospital center. METHODS: Retrospective study of consecutive patients referred for neurology inpatient consultation between 01/01/2020 and 31/12/2022. We analyzed referrals, patients' characteristics, and the approach taken...
February 21, 2024: European Neurology
https://read.qxmd.com/read/38362576/acute-coronary-thrombosis-due-to-heparin-induced-thrombocytopenia-following-improved-covid-19-pneumonia-a-case-report
#8
Yoshinori Sakamoto, Atsuhiko Sugimoto, Harukazu Iseki
UNLABELLED: A 45-year-old male with anteroseptal myocardial infarction was referred to our hospital. The patient was previously admitted to another hospital with coronavirus disease-2019 pneumonia for 2 weeks; he was discharged 2 weeks before presentation to our institution. He received conventional treatment for coronavirus disease-2019, including administration of heparin. A moderate decrease in platelet count was observed on admission, and emergent angiography was performed under a definitive diagnosis of acute coronary syndrome...
February 2024: Journal of Cardiology Cases
https://read.qxmd.com/read/38348469/the-comparison-of-the-initial-timi-flow-grade-in-acute-st-elevation-myocardial-infarction-patients-receiving-ticagrelor-vs-clopidogrel-before-undergoing-primary-percutaneous-coronary-intervention-a-prospective-cohort-study
#9
JOURNAL ARTICLE
Amin Elahifar, Ali Rafati, Mohammad Javad Alemzadeh-Ansari, Yeganeh Pasebani, Behshad Naghshtabrizi, Younes Mohammadi, Seyed Kianoosh Hosseini
OBJECTIVE: Primary percutaneous coronary intervention (PCI) is the best treatment for acute ST-elevation myocardial infarction (STEMI). Evidence is in favor of ticagrelor over clopidegrel in STEMI patients regarding the reduction of stent thrombosis risk during and after PCI. We compared initial thrombolysis in myocardial infarction (TIMI) flow in STEMI patients on ticagrelor vs. clopidogrel. METHODS: This prospective cohort recruited 160 patients with acute STEMI, referred to the emergency department of Farshchian Heart Center, during March 2018-2019...
2024: Cardiology Research and Practice
https://read.qxmd.com/read/38333299/right-ventricular-infarction-epidemiological-clinical-and-angiographic-characteristics-and-the-outcomes-through-the-experience-of-a-moroccan-cardiology-department
#10
JOURNAL ARTICLE
Youssra Bouhaddoune, Amine Bouchlarhem, Zakaria Bazid, Nabila Ismaili, Noha El Ouafi
BACKGROUND: Acute myocardial infarction (MI) is a major cause of cardiovascular mortality, which is the leading cause of death in the world. Our objective in this study was to evaluate the epidemiological, clinical, and angiographic features of right ventricular infarction (RVI), as well as its complications and its therapeutic approaches. PATIENTS AND METHODS: It is a single-centered retrospective descriptive study conducted over a period of 2 years from November 2018 to October 2020...
February 2024: Annals of Medicine and Surgery
https://read.qxmd.com/read/38318910/-index-of-microcirculatory-resistance-is-associated-with-left-ventricular-remodeling-in-patients-with-acute-anterior-st-segment-elevation-myocardial-infarction-undergoing-emergency-primary-percutaneous-coronary-intervention
#11
JOURNAL ARTICLE
Fangfang Wang, Fumeng Liang, Nan Li, Xiaoxiao Wang, Jiangli Han, Lijun Guo
OBJECTIVE: To evaluate whether index of microcirculatory resistance (IMR) is associated with left ventricular (LV) remodeling in acute anterior ST elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PPCI). METHODS: This was a single-center retrospective cohort study. The patients with first anterior STEMI who received PPCI from January 2014 to August 2017 in Peking University Third Hospital was enrolled. After PPCI, IMR was measured immediately by using pressure/temperature guidewire...
February 18, 2024: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://read.qxmd.com/read/38300500/remote-intensive-management-to-improve-antiplatelet-adherence-in-acute-myocardial-infarction-a-secondary-analysis-of-the-randomized-controlled-immaculate-trial
#12
JOURNAL ARTICLE
Hui Wen Sim, Karen W L Koh, Sock-Cheng Poh, Siew Pang Chan, Stephanie Marchesseau, Devinder Singh, Yiying Han, Faclin Ng, Eleanor Lim, Joseph F Prabath, Chi-Hang Lee, Ruth Chen, Leonardo Carvalho, Sock-Hwee Tan, Joshua P Y Loh, Jack W C Tan, Karishma Kuwelker, R M Amanullah, Chee-Tang Chin, James W L Yip, Choy-Yee Lee, Juvena Gan, Chew-Yong Lo, Hee-Hwa Ho, Derek J Hausenloy, Bee-Choo Tai, A Mark Richards, Mark Y Chan
This study aim to investigate if remote intensive coaching for the first 6 months post-AMI will improve adherence to the twice-a-day antiplatelet medication, ticagrelor. Between July 8, 2015, to March 29, 2019, AMI patients were randomly assigned to remote intensive management (RIM) or standard care (SC). RIM participants underwent 6 months of weekly then two-weekly consultations to review medication side effects and medication adherence coaching by a centralized nurse practitioner team, whereas SC participants received usual cardiologist face-to-face consultations...
February 1, 2024: Journal of Thrombosis and Thrombolysis
https://read.qxmd.com/read/38279297/coronary-slow-flow-phenomenon-in-takotsubo-syndrome-the-prevalence-clinical-determinants-and-long-term-prognostic-impact
#13
JOURNAL ARTICLE
Konrad Stępień, Karol Nowak, Aleksandra Karcińska, Grzegorz Horosin, Alicia Del Carmen Yika, Julia Lenart, Anna Górowska, Sylwia Iwańczyk, Mateusz Podolec, Aleksander Siniarski, Jadwiga Nessler, Jarosław Zalewski
Patients with takotsubo syndrome (TTS) may present coronary slow flow (CSF) in angiography performed in the acute myocardial infarction (MI). However, the detailed clinical relevance and its long-term impact remain poorly understood. Among 7771 MI patients hospitalized between 2012 and 2019, TTS was identified in 82 (1.1%) subjects. The epicardial blood flow was assessed with thrombolysis in myocardial infarction (TIMI) scale and corrected TIMI frame count (TFC), whereas myocardial perfusion with TIMI myocardial perfusion grade (TMPG)...
January 20, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38275111/lorenzutcomparison-of-pharmacokinetic-properties-of-alteplase-and-tenecteplase-the-future-of-thrombolysis-in-acute-ischemic-stroke
#14
REVIEW
Alessandro Marè, Simone Lorenzut, Francesco Janes, Carolina Gentile, Roberto Marinig, Yan Tereshko, Gian Luigi Gigli, Mariarosaria Valente, Giovanni Merlino
INTRODUCTION: The drug most frequently used for thrombolysis in cases of acute ischemic stroke (AIS) is alteplase. However, there is moderate-to-high-quality evidence that tenecteplase has similar or higher efficacy and safety. With improved pharmacokinetic properties over alteplase, tenecteplase could be a significant advantage in treating AIS. AREAS COVERED: After conducting an extensive search on Scopus and PubMed, this manuscript reviews and compares the pharmacokinetic properties of alteplase and tenecteplase...
January 26, 2024: Expert Opinion on Drug Metabolism & Toxicology
https://read.qxmd.com/read/38264959/aspirin-loading-and-coronary-no-reflow-after-percutaneous-coronary-intervention-in-patients-with-acute-myocardial-infarction
#15
JOURNAL ARTICLE
Gjin Ndrepepa, Salvatore Cassese, Erion Xhepa, Michael Joner, Hendrik B Sager, Sebastian Kufner, Karl-Ludwig Laugwitz, Heribert Schunkert, Adnan Kastrati
BACKGROUND: The association of aspirin loading with the risk of coronary no-reflow (CNR) after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) has not been investigated. We assessed the association of aspirin loading before PCI with CNR in patients with AMI. MATERIALS AND METHODS: This study included 3100 patients with AMI undergoing PCI. Of them, 2812 patients received aspirin loading (a single oral [or chewed] or intravenous dose of 150-300 mg) and 288 patients did not receive aspirin loading before PCI...
January 24, 2024: European Journal of Clinical Investigation
https://read.qxmd.com/read/38260108/reliability-of-fractional-flow-reserve-in-non-infarct-related-arteries-in-st-segment-elevation-myocardial-infarction-patients-undergoing-a-pharmaco-invasive-approach
#16
JOURNAL ARTICLE
Ayush Shukla, Sudhanshu K Dwivedi, Sharad Chandra, Gaurav Chaudhary, Akhil Sharma, Rishi Sethi, Akshyaya Pradhan, Pravesh Vishwakarma, Monika Bhandari, Abhishek Singh
Objectives We investigated the reproducibility of fractional flow reserve (FFR) of significant stenoses (≥70% narrowing) in the non-infarct related artery (NIRA) during the pharmaco-invasive percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) within 24 hours of thrombolysis and at a follow up of 2-3 weeks. Background STEMI with multivessel disease has worse outcomes. The benefits of FFR-directed PCI of NIRA at the time of primary PCI are yet controversial...
January 2024: Curēus
https://read.qxmd.com/read/38255101/spontaneous-coronary-artery-dissection-as-a-cause-of-acute-myocardial-infarction-in-covid-19-patients-a-case-report-and-review-of-the-literature
#17
Angeliki Papageorgiou, Athanasios Moulias, Athanasios Papageorgiou, Theodoros Karampitsakos, Anastasios Apostolos, Grigorios Tsigkas, Periklis Davlouros
Patients with COVID-19 often experience significant cardiovascular complications, including heart failure, myocarditis, and acute coronary syndrome. We present the case of a male patient with severe COVID-19 pneumonia, complicated with inferior ST-segment elevation myocardial infarction (STEMI), which was attributed to spontaneous coronary artery dissection (SCAD). We also make a review of the literature on case reports of patients with COVID-19 and acute myocardial infarction due to SCAD. Through these clinical cases, a potential correlation between SCAD and COVID-19 infection is implied...
January 16, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38233341/severe-covid-19-post-pregnancy-complicated-by-acute-thromboemboli-resulting-in-st-elevation-myocardial-infarction-a-case-report
#18
JOURNAL ARTICLE
Danni Fu, Byung Joon Park, Gaurav Rao, John Makaryus
Introduction: It has been shown that pregnancy can cause alterations in the severity of COVID-19 infection. We demonstrate an immediate post-partum patient diagnosed with severe COVID-19 and subsequently developed acute thrombosis of coronary artery. Case Summary: 35-year-old female unvaccinated for COVID-19 presented in labor and delivered on the same day. Several hours later, she was found to be in respiratory distress and tested positive for COVID-19. On day 7, computerized tomography (CT) of chest revealed bilateral pneumonia and pneumomediastinum...
January 17, 2024: Perfusion
https://read.qxmd.com/read/38233295/informing-utstein-style-reporting-guidelines-for-prehospital-thrombolysis-a-scoping-review
#19
JOURNAL ARTICLE
Louis Jenkins, Tania Johnston, Richard Armour, Sonja Maria
BACKGROUND: Rural Australians with acute myocardial infarction (AMI) face higher mortality rates due to limited access to specialised cardiac services. Paramedic-administered prehospital thrombolysis (PHT) has emerged as an alternative to primary percutaneous intervention (pPCI) for patients facing barriers or delays to cardiac care. There is variability in PHT practices among Australian ambulance services, lacking standardised definitions and outcome measures. The aim of this scoping review was to identify quality indicators and influencing factors associated with outcomes for patients receiving PHT...
January 16, 2024: Australasian emergency care
https://read.qxmd.com/read/38231041/the-emerging-role-of-mechanical-thrombectomy-in-acute-dvt-management
#20
JOURNAL ARTICLE
Efthymios D Avgerinos, Vasileios Bouris, Houman Jalaie
Catheter directed thrombolysis (CDT) and pharmacomechanical thrombectomy in various technical combinations have been the main driver of acute deep venous interventions for over a decade. While the majority of high-level evidence was based on it, CDT requires longer procedural care and is associated to a small but not negligible bleeding risk. Contemporary DVT intervention, following the paradigm shift in myocardial infarction and stroke management, has steadily migrated towards minimizing or eliminating thrombolytics due to the introduction of mechanical/aspiration thrombectomy...
January 17, 2024: Journal of Cardiovascular Surgery
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