Casandra Dolovich, Leigh Anne Shafer, Lesley A Graff, Kathy Vagianos, Kelcie Witges, Laura E Targownik, Charles N Bernstein
BACKGROUND: Among women of reproductive age with inflammatory bowel disease (IBD), we aimed to assess the relationship of hormonal contraceptives (HCs) with IBD-related symptoms, and intestinal inflammation. METHODS: A nested cohort of women in the longitudinal Manitoba Living with IBD Study, ages 18 to 49, were followed for 1 year, with bi-weekly online surveys. This included a validated measure of disease activity; IBD Symptom Inventory (IBDSI), and stool samples obtained at 3 time-points for assessment of fecal calprotectin (FCAL)...
March 1, 2024: Journal of Clinical Gastroenterology