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https://read.qxmd.com/read/30773883/photocatalysis-enhancement-for-programmable-killing-of-hepatocellular-carcinoma-through-self-compensation-mechanisms-based-on-black-phosphorus-quantum-dot-hybridized-nanocatalysts
#1
Shanyou Lan, Ziguo Lin, Da Zhang, Yongyi Zeng, Xiaolong Liu
Recently reported black phosphorus quantum dots (BPQDs) possess unique photocatalysis activities. However, the environmental instability accompanied by hypoxic tumor microenvironment (TME) seriously hindered the bio-applications of BPQDs, especially in oxygen-dependent photodynamic therapy (PDT). Here, we construct a hepatocellular carcinoma (HCC) specific targeting aptamer "TLS11a" decorated BPQDs-hybridized nanocatalyst which can specifically target HCC tumor cells and self-compensate oxygen (O2) into hypoxic TME for enhancing PDT efficiency...
February 18, 2019: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/30772259/purification-and-biophysical-characterization-of-a-mannose-n-acetyl-d-glucosamine-specific-lectin-from-machaerium-acutifolium-and-its-effect-on-inhibition-of-orofacial-pain-via-trpv1-receptor
#2
Ana L E Santos, Gerlânia O Leite, Romulo F Carneiro, Renato R Roma, Valdenice F Santos, Maria H C Santos, Raquel O Pereira, Rafael C Silva, Celso S Nagano, Alexandre H Sampaio, Bruno A M Rocha, Plinio Delatorre, Adriana R Campos, Claudener S Teixeira
A new mannose/N-acetyl-dglucosamine-specific lectin, named MaL, was purified from seeds of Machaerium acutifolium by precipitation with ammonium sulfate, followed by affinity and ion-exchange chromatography. MaL haemagglutinates either native rabbit erythrocytes or those treated with proteolytic enzymes. MaL is highly stable by the ability to maintain its haemagglutinating activity after exposure to temperatures up to 50 °C. The lectin haemagglutinating activity was optimum between pH 6.0 and 7.0 and inhibited after incubation with d-mannose and N-acetyl-d-glucosamine and α-methyl-d-mannopyranoside...
February 14, 2019: Archives of Biochemistry and Biophysics
https://read.qxmd.com/read/30766533/macrophage-activation-like-syndrome-a-distinct-entity-leading-to-early-death-in-sepsis
#3
REVIEW
Eleni Karakike, Evangelos J Giamarellos-Bourboulis
Hemophagocytic lymphohistocytosis (HLH) is characterized by fulminant cytokine storm leading to multiple organ dysfunction and high mortality. HLH is classified into familial (fHLH) and into secondary (sHLH). fHLH is rare and it is due to mutations of genes encoding for perforin or excretory granules of natural killer (NK) cells of CD8-lymphocytes. sHLH is also known as macrophage activation syndrome (MAS). Macrophage activation syndrome (MAS) in adults is poorly studied. Main features are fever, hepatosplenomegaly, hepatobiliary dysfunction (HBD), coagulopathy, cytopenia of two to three cell lineages, increased triglycerides and hemophagocytosis in the bone marrow...
2019: Frontiers in Immunology
https://read.qxmd.com/read/30755122/mid-term-results-with-a-neck-preserving-femoral-stem-for-total-hip-arthroplasty
#4
Giampaolo Rinaldi, Dario Capitani, Fabio Maspero, Valentina Scita
INTRODUCTION: This prospective study aims to evaluate the mid-term clinical and radiological performance of a new short, neck-preserving femoral stem in total hip arthroplasty (THA). PATIENTS AND METHODS: 178 consecutive patients (190 hips) underwent THA from November 2008 to July 2016. Mean follow-up is 62.4 months. Women make up 41% of the cohort at a mean age of 50 ± 4 years, with primary hip osteoarthritis as the main complaint. All patients underwent radiological evaluation using the modified Gruen method, and clinical assessment via the Harris Hip Score (HHS), preoperatively and at 1, 6, 12, 24, 60, 80 and 106 months post-op...
November 2018: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://read.qxmd.com/read/30754057/transhepatic-forceps-biopsy-after-ptcd-for-histological-assessment-of-bile-duct-stenoses-or-occlusions
#5
Eva-Marie Warnken, Michael Uder, Hubert Stein, Michael Wucherer, Michael Lell, Herbert Muschweck, Ralf Adamus
PURPOSE:  The goal of this study was to evaluate the experience of 11 years of wire-guided forceps biopsy via PTCD in patients with obstructive jaundice. MATERIALS AND METHODS:  In a retrospective approach, 56 biopsies in 51 patients were analyzed (22 female, 29 male). Data was collected from 2006 to 2016. Mean age was 71 years (range: 34 - 86 years). Data was extracted from dig. Patients' records (KIS, PACS, RIS) to be analyzed in Microsoft Excel. RESULTS:  All 56 procedures were technically successful...
February 2019: Zeitschrift Für Gastroenterologie
https://read.qxmd.com/read/30739920/conflict-management-in-healthcare
#6
Rano Mal Piryani, Suneel Piryani
The conflict is a disagreement within oneself or differences or dispute among persons that has potential to cause harm. It is inevitable and may occur in any profession including healthcare. It could be among any group of healthcare professionals or healthcare team between different group of healthcare professionals or between patient and any of the member of healthcare team. The conflict has a critical effect on the competence, confidence, and morale of healthcare professionals. Consequently, it affects patient care too...
January 28, 2019: Journal of Nepal Health Research Council
https://read.qxmd.com/read/30738734/multicentre-post-evar-surveillance-evaluation-study-evar-screen
#7
Matthew J Grima, Alan Karthikesalingam, Peter J Holt
OBJECTIVE: Surveillance imaging is considered mandatory after endovascular aneurysm repair (EVAR), but many patients are lost to follow up and the impact of this is poorly understood. This study aimed to examine compliance with post-operative surveillance in the UK and the impact of mal-/non-compliance on endograft re-interventions and survival. METHODS: EVAR-SCREEN centres reported EVAR for intact infrarenal abdominal aortic aneurysms (AAA) from 1 January 2007 to 31 December 2010, with follow up included up to 31 July 2014...
February 6, 2019: European Journal of Vascular and Endovascular Surgery
https://read.qxmd.com/read/30738103/differential-gene-expression-in-the-mesocorticolimbic-system-of-innately-high-and-low-impulsive-rats
#8
Gerard M Moloney, Wesley E P A van Oeffelen, Feargal J Ryan, Marcel van de Wouw, Caitlin Cowan, Marcus J Claesson, Harriet Schellekens, Timothy G Dinan, John F Cryan
Impulsivity is an important component of many psychiatric illnesses and has been associated with a number of psychiatric disorders such as bipolar disorder and attention deficit / hyperactivity disorder (ADHD). Exploring the different aspects of impulsive behaviour and assigning these to specific neurobiological pathways would advance our interpretation of disorders for which impulsivity is key. Pharmacological studies have implicated a number of neurotransmitters in impulsivity, which in turn have been shown to be affected by several genes in both rodent and human studies of impulsivity...
February 6, 2019: Behavioural Brain Research
https://read.qxmd.com/read/30733883/aneurysms-of-pancreaticoduodenal-artery-due-to-median-arcuate-ligament-syndrome-treated-by-open-surgery-and-laparoscopic-surgery
#9
Satoshi Tokuda, Shunsuke Sakuraba, Hajime Orita, Mutsumi Sakurada, Tomoyuki Kushida, Hiroshi Maekawa, Koichi Sato
Introduction: There are many possible causes of an abdominal visceral aneurysm, including the obstruction of the celiac artery by the median arcuate ligament (MAL). We report two cases of an aneurysm of the pancreaticoduodenal artery due to MAL syndrome that we treated surgically. Case Presentation: Case 1: a 66-year-old Japanese woman was diagnosed with a rupture of an aneurysm of the inferior pancreaticoduodenal artery. Because of the difficulty of endovascular therapy, we performed an emergency operation...
2019: Case Reports in Surgery
https://read.qxmd.com/read/30720313/search-for-the-higgs-boson-decaying-to-two-muons-in-proton-proton-collisions-at-sqrt-s-13-tev
#10
A M Sirunyan, A Tumasyan, W Adam, F Ambrogi, E Asilar, T Bergauer, J Brandstetter, E Brondolin, M Dragicevic, J Erö, A Escalante Del Valle, M Flechl, R Frühwirth, V M Ghete, J Hrubec, M Jeitler, N Krammer, I Krätschmer, D Liko, T Madlener, I Mikulec, N Rad, H Rohringer, J Schieck, R Schöfbeck, M Spanring, D Spitzbart, A Taurok, W Waltenberger, J Wittmann, C-E Wulz, M Zarucki, V Chekhovsky, V Mossolov, J Suarez Gonzalez, E A De Wolf, D Di Croce, X Janssen, J Lauwers, M Pieters, M Van De Klundert, H Van Haevermaet, P Van Mechelen, N Van Remortel, S Abu Zeid, F Blekman, J D'Hondt, I De Bruyn, J De Clercq, K Deroover, G Flouris, D Lontkovskyi, S Lowette, I Marchesini, S Moortgat, L Moreels, Q Python, K Skovpen, S Tavernier, W Van Doninck, P Van Mulders, I Van Parijs, D Beghin, B Bilin, H Brun, B Clerbaux, G De Lentdecker, H Delannoy, B Dorney, G Fasanella, L Favart, R Goldouzian, A Grebenyuk, A K Kalsi, T Lenzi, J Luetic, E Starling, C Vander Velde, P Vanlaer, D Vannerom, T Cornelis, D Dobur, A Fagot, M Gul, I Khvastunov, D Poyraz, C Roskas, D Trocino, M Tytgat, W Verbeke, B Vermassen, M Vit, N Zaganidis, H Bakhshiansohi, O Bondu, S Brochet, G Bruno, C Caputo, P David, C Delaere, M Delcourt, B Francois, A Giammanco, G Krintiras, V Lemaitre, A Magitteri, A Mertens, M Musich, K Piotrzkowski, A Saggio, M Vidal Marono, S Wertz, J Zobec, F L Alves, G A Alves, L Brito, G Correia Silva, C Hensel, A Moraes, M E Pol, P Rebello Teles, E Belchior Batista Das Chagas, W Carvalho, J Chinellato, E Coelho, E M Da Costa, G G Da Silveira, D De Jesus Damiao, C De Oliveira Martins, S Fonseca De Souza, H Malbouisson, D Matos Figueiredo, M Melo De Almeida, C Mora Herrera, L Mundim, H Nogima, W L Prado Da Silva, L J Sanchez Rosas, A Santoro, A Sznajder, M Thiel, E J Tonelli Manganote, F Torres Da Silva De Araujo, A Vilela Pereira, S Ahuja, C A Bernardes, L Calligaris, T R Fernandez Perez Tomei, E M Gregores, P G Mercadante, S F Novaes, Sandra S Padula, D Romero Abad, A Aleksandrov, R Hadjiiska, P Iaydjiev, A Marinov, M Misheva, M Rodozov, M Shopova, G Sultanov, A Dimitrov, L Litov, B Pavlov, P Petkov, W Fang, X Gao, L Yuan, M Ahmad, J G Bian, G M Chen, H S Chen, M Chen, Y Chen, C H Jiang, D Leggat, H Liao, Z Liu, F Romeo, S M Shaheen, A Spiezia, J Tao, C Wang, Z Wang, E Yazgan, H Zhang, J Zhao, Y Ban, G Chen, J Li, Q Li, S Liu, Y Mao, S J Qian, D Wang, Z Xu, Y Wang, C Avila, A Cabrera, C A Carrillo Montoya, L F Chaparro Sierra, C Florez, C F González Hernández, M A Segura Delgado, B Courbon, N Godinovic, D Lelas, I Puljak, T Sculac, Z Antunovic, M Kovac, V Brigljevic, D Ferencek, K Kadija, B Mesic, A Starodumov, T Susa, M W Ather, A Attikis, G Mavromanolakis, J Mousa, C Nicolaou, F Ptochos, P A Razis, H Rykaczewski, M Finger, M Finger, E Ayala, E Carrera Jarrin, H Abdalla, A A Abdelalim, S Khalil, S Bhowmik, A Carvalho Antunes De Oliveira, R K Dewanjee, K Ehataht, M Kadastik, L Perrini, M Raidal, C Veelken, P Eerola, H Kirschenmann, J Pekkanen, M Voutilainen, J Havukainen, J K Heikkilä, T Järvinen, V Karimäki, R Kinnunen, T Lampén, K Lassila-Perini, S Laurila, S Lehti, T Lindén, P Luukka, T Mäenpää, H Siikonen, E Tuominen, J Tuominiemi, T Tuuva, M Besancon, F Couderc, M Dejardin, D Denegri, J L Faure, F Ferri, S Ganjour, A Givernaud, P Gras, G Hamel de Monchenault, P Jarry, C Leloup, E Locci, J Malcles, G Negro, J Rander, A Rosowsky, M Ö Sahin, M Titov, A Abdulsalam, C Amendola, I Antropov, F Beaudette, P Busson, C Charlot, R Granier de Cassagnac, I Kucher, S Lisniak, A Lobanov, J Martin Blanco, M Nguyen, C Ochando, G Ortona, P Paganini, P Pigard, R Salerno, J B Sauvan, Y Sirois, A G Stahl Leiton, Y Yilmaz, A Zabi, A Zghiche, J-L Agram, J Andrea, D Bloch, J-M Brom, E C Chabert, V Cherepanov, C Collard, E Conte, J-C Fontaine, D Gelé, U Goerlach, M Jansová, A-C Le Bihan, N Tonon, P Van Hove, S Gadrat, S Beauceron, C Bernet, G Boudoul, N Chanon, R Chierici, D Contardo, P Depasse, H El Mamouni, J Fay, L Finco, S Gascon, M Gouzevitch, G Grenier, B Ille, F Lagarde, I B Laktineh, H Lattaud, M Lethuillier, L Mirabito, A L Pequegnot, S Perries, A Popov, V Sordini, M Vander Donckt, S Viret, S Zhang, A Khvedelidze, Z Tsamalaidze, C Autermann, L Feld, M K Kiesel, K Klein, M Lipinski, M Preuten, M P Rauch, C Schomakers, J Schulz, M Teroerde, B Wittmer, V Zhukov, A Albert, D Duchardt, M Endres, M Erdmann, S Erdweg, T Esch, R Fischer, S Ghosh, A Güth, T Hebbeker, C Heidemann, K Hoepfner, S Knutzen, L Mastrolorenzo, M Merschmeyer, A Meyer, P Millet, S Mukherjee, T Pook, M Radziej, H Reithler, M Rieger, F Scheuch, A Schmidt, D Teyssier, S Thüer, G Flügge, O Hlushchenko, B Kargoll, T Kress, A Künsken, T Müller, A Nehrkorn, A Nowack, C Pistone, O Pooth, H Sert, A Stahl, M Aldaya Martin, T Arndt, C Asawatangtrakuldee, I Babounikau, K Beernaert, O Behnke, U Behrens, A Bermúdez Martínez, D Bertsche, A A Bin Anuar, K Borras, V Botta, A Campbell, P Connor, C Contreras-Campana, F Costanza, V Danilov, A De Wit, M M Defranchis, C Diez Pardos, D Domínguez Damiani, G Eckerlin, T Eichhorn, A Elwood, E Eren, E Gallo, A Geiser, J M Grados Luyando, A Grohsjean, P Gunnellini, M Guthoff, A Harb, J Hauk, H Jung, M Kasemann, J Keaveney, C Kleinwort, J Knolle, D Krücker, W Lange, A Lelek, T Lenz, K Lipka, W Lohmann, R Mankel, I-A Melzer-Pellmann, A B Meyer, M Meyer, M Missiroli, G Mittag, J Mnich, V Myronenko, S K Pflitsch, D Pitzl, A Raspereza, M Savitskyi, P Saxena, P Schütze, C Schwanenberger, R Shevchenko, A Singh, N Stefaniuk, H Tholen, A Vagnerini, G P Van Onsem, R Walsh, Y Wen, K Wichmann, C Wissing, O Zenaiev, R Aggleton, S Bein, A Benecke, V Blobel, M Centis Vignali, T Dreyer, E Garutti, D Gonzalez, J Haller, A Hinzmann, M Hoffmann, A Karavdina, R Klanner, R Kogler, N Kovalchuk, S Kurz, V Kutzner, J Lange, D Marconi, J Multhaup, M Niedziela, D Nowatschin, A Perieanu, A Reimers, O Rieger, C Scharf, P Schleper, S Schumann, J Schwandt, J Sonneveld, H Stadie, G Steinbrück, F M Stober, M Stöver, D Troendle, E Usai, A Vanhoefer, B Vormwald, M Akbiyik, C Barth, M Baselga, S Baur, E Butz, R Caspart, T Chwalek, F Colombo, W De Boer, A Dierlamm, N Faltermann, B Freund, M Giffels, M A Harrendorf, F Hartmann, S M Heindl, U Husemann, F Kassel, I Katkov, S Kudella, H Mildner, M U Mozer, Th Müller, M Plagge, G Quast, K Rabbertz, M Schröder, I Shvetsov, G Sieber, H J Simonis, R Ulrich, S Wayand, M Weber, T Weiler, S Williamson, C Wöhrmann, R Wolf, G Anagnostou, G Daskalakis, T Geralis, A Kyriakis, D Loukas, G Paspalaki, I Topsis-Giotis, G Karathanasis, S Kesisoglou, A Panagiotou, N Saoulidou, E Tziaferi, K Vellidis, K Kousouris, I Papakrivopoulos, Y Tsipolitis, I Evangelou, C Foudas, P Gianneios, P Katsoulis, P Kokkas, S Mallios, N Manthos, I Papadopoulos, E Paradas, J Strologas, F A Triantis, D Tsitsonis, M Csanad, N Filipovic, P Major, M I Nagy, G Pasztor, O Surányi, G I Veres, G Bencze, C Hajdu, D Horvath, Á Hunyadi, F Sikler, T Á Vámi, V Veszpremi, G Vesztergombi, N Beni, S Czellar, J Karancsi, A Makovec, J Molnar, Z Szillasi, M Bartók, P Raics, Z L Trocsanyi, B Ujvari, S Choudhury, J R Komaragiri, S Bahinipati, P Mal, K Mandal, A Nayak, D K Sahoo, S K Swain, S Bansal, S B Beri, V Bhatnagar, S Chauhan, R Chawla, N Dhingra, R Gupta, A Kaur, A Kaur, M Kaur, S Kaur, R Kumar, P Kumari, M Lohan, A Mehta, S Sharma, J B Singh, G Walia, A Bhardwaj, B C Choudhary, R B Garg, M Gola, S Keshri, Ashok Kumar, S Malhotra, M Naimuddin, P Priyanka, K Ranjan, Aashaq Shah, R Sharma, R Bhardwaj, M Bharti, R Bhattacharya, S Bhattacharya, U Bhawandeep, D Bhowmik, S Dey, S Dutt, S Dutta, S Ghosh, K Mondal, S Nandan, A Purohit, P K Rout, A Roy, S Roy Chowdhury, S Sarkar, M Sharan, B Singh, S Thakur, P K Behera, R Chudasama, D Dutta, V Jha, V Kumar, P K Netrakanti, L M Pant, P Shukla, T Aziz, M A Bhat, S Dugad, B Mahakud, S Mitra, G B Mohanty, N Sur, B Sutar, Ravindra Kumar Verma, S Banerjee, S Bhattacharya, S Chatterjee, P Das, M Guchait, Sa Jain, S Kumar, M Maity, G Majumder, K Mazumdar, N Sahoo, T Sarkar, S Chauhan, S Dube, V Hegde, A Kapoor, K Kothekar, S Pandey, A Rane, S Sharma, S Chenarani, E Eskandari Tadavani, S M Etesami, M Khakzad, M Mohammadi Najafabadi, M Naseri, F Rezaei Hosseinabadi, B Safarzadeh, M Zeinali, M Felcini, M Grunewald, M Abbrescia, C Calabria, A Colaleo, D Creanza, L Cristella, N De Filippis, M De Palma, A Di Florio, F Errico, L Fiore, A Gelmi, G Iaselli, S Lezki, G Maggi, M Maggi, G Miniello, S My, S Nuzzo, A Pompili, G Pugliese, R Radogna, A Ranieri, G Selvaggi, A Sharma, L Silvestris, R Venditti, P Verwilligen, G Zito, G Abbiendi, C Battilana, D Bonacorsi, L Borgonovi, S Braibant-Giacomelli, L Brigliadori, R Campanini, P Capiluppi, A Castro, F R Cavallo, S S Chhibra, G Codispoti, M Cuffiani, G M Dallavalle, F Fabbri, A Fanfani, P Giacomelli, C Grandi, L Guiducci, S Marcellini, G Masetti, A Montanari, F L Navarria, A Perrotta, A M Rossi, T Rovelli, G P Siroli, N Tosi, S Albergo, A Di Mattia, R Potenza, A Tricomi, C Tuve, G Barbagli, K Chatterjee, V Ciulli, C Civinini, R D'Alessandro, E Focardi, G Latino, P Lenzi, M Meschini, S Paoletti, L Russo, G Sguazzoni, D Strom, L Viliani, L Benussi, S Bianco, F Fabbri, D Piccolo, F Primavera, F Ferro, F Ravera, E Robutti, S Tosi, A Benaglia, A Beschi, L Brianza, F Brivio, V Ciriolo, M E Dinardo, S Fiorendi, S Gennai, A Ghezzi, P Govoni, M Malberti, S Malvezzi, R A Manzoni, D Menasce, L Moroni, M Paganoni, D Pedrini, S Pigazzini, S Ragazzi, T Tabarelli de Fatis, S Buontempo, N Cavallo, A Di Crescenzo, S Di Guida, F Fabozzi, F Fienga, G Galati, A O M Iorio, W A Khan, L Lista, S Meola, P Paolucci, C Sciacca, E Voevodina, P Azzi, N Bacchetta, L Benato, D Bisello, A Boletti, A Bragagnolo, R Carlin, P Checchia, M Dall'Osso, P De Castro Manzano, T Dorigo, U Dosselli, F Gasparini, U Gasparini, A Gozzelino, S Lacaprara, P Lujan, M Margoni, A T Meneguzzo, N Pozzobon, P Ronchese, R Rossin, F Simonetto, A Tiko, E Torassa, S Ventura, M Zanetti, A Braghieri, A Magnani, P Montagna, S P Ratti, V Re, M Ressegotti, C Riccardi, P Salvini, I Vai, P Vitulo, L Alunni Solestizi, M Biasini, G M Bilei, C Cecchi, D Ciangottini, L Fanò, P Lariccia, E Manoni, G Mantovani, V Mariani, M Menichelli, A Rossi, A Santocchia, D Spiga, K Androsov, P Azzurri, G Bagliesi, L Bianchini, T Boccali, L Borrello, R Castaldi, M A Ciocci, R Dell'Orso, G Fedi, L Giannini, A Giassi, M T Grippo, F Ligabue, E Manca, G Mandorli, A Messineo, F Palla, A Rizzi, P Spagnolo, R Tenchini, G Tonelli, A Venturi, P G Verdini, L Barone, F Cavallari, M Cipriani, N Daci, D Del Re, E Di Marco, M Diemoz, S Gelli, E Longo, B Marzocchi, P Meridiani, G Organtini, F Pandolfi, R Paramatti, F Preiato, S Rahatlou, C Rovelli, F Santanastasio, N Amapane, R Arcidiacono, S Argiro, M Arneodo, N Bartosik, R Bellan, C Biino, N Cartiglia, F Cenna, M Costa, R Covarelli, N Demaria, B Kiani, C Mariotti, S Maselli, E Migliore, V Monaco, E Monteil, M Monteno, M M Obertino, L Pacher, N Pastrone, M Pelliccioni, G L Pinna Angioni, A Romero, M Ruspa, R Sacchi, K Shchelina, V Sola, A Solano, A Staiano, S Belforte, V Candelise, M Casarsa, F Cossutti, G Della Ricca, F Vazzoler, A Zanetti, D H Kim, G N Kim, M S Kim, J Lee, S Lee, S W Lee, C S Moon, Y D Oh, S Sekmen, D C Son, Y C Yang, H Kim, D H Moon, G Oh, J Goh, T J Kim, S Cho, S Choi, Y Go, D Gyun, S Ha, B Hong, Y Jo, K Lee, K S Lee, S Lee, J Lim, S K Park, Y Roh, H Kim, J Almond, J Kim, J S Kim, H Lee, K Lee, K Nam, S B Oh, B C Radburn-Smith, S H Seo, U K Yang, H D Yoo, G B Yu, H Kim, J H Kim, J S H Lee, I C Park, Y Choi, C Hwang, J Lee, I Yu, V Dudenas, A Juodagalvis, J Vaitkus, I Ahmed, Z A Ibrahim, M A B Md Ali, F Mohamad Idris, W A T Wan Abdullah, M N Yusli, Z Zolkapli, H Castilla-Valdez, E De La Cruz-Burelo, M C Duran-Osuna, I Heredia-De La Cruz, R Lopez-Fernandez, J Mejia Guisao, R I Rabadan-Trejo, G Ramirez-Sanchez, R Reyes-Almanza, A Sanchez-Hernandez, S Carrillo Moreno, C Oropeza Barrera, F Vazquez Valencia, J Eysermans, I Pedraza, H A Salazar Ibarguen, C Uribe Estrada, A Morelos Pineda, D Krofcheck, S Bheesette, P H Butler, A Ahmad, M Ahmad, M I Asghar, Q Hassan, H R Hoorani, A Saddique, M A Shah, M Shoaib, M Waqas, H Bialkowska, M Bluj, B Boimska, T Frueboes, M Górski, M Kazana, K Nawrocki, M Szleper, P Traczyk, P Zalewski, K Bunkowski, A Byszuk, K Doroba, A Kalinowski, M Konecki, J Krolikowski, M Misiura, M Olszewski, A Pyskir, M Walczak, P Bargassa, C Beirão Da Cruz E Silva, A Di Francesco, P Faccioli, B Galinhas, M Gallinaro, J Hollar, N Leonardo, L Lloret Iglesias, M V Nemallapudi, J Seixas, G Strong, O Toldaiev, D Vadruccio, J Varela, V Alexakhin, A Golunov, I Golutvin, N Gorbounov, I Gorbunov, A Kamenev, V Karjavin, A Lanev, A Malakhov, V Matveev, P Moisenz, V Palichik, V Perelygin, M Savina, S Shmatov, S Shulha, N Skatchkov, V Smirnov, A Zarubin, V Golovtsov, Y Ivanov, V Kim, E Kuznetsova, P Levchenko, V Murzin, V Oreshkin, I Smirnov, D Sosnov, V Sulimov, L Uvarov, S Vavilov, A Vorobyev, Yu Andreev, A Dermenev, S Gninenko, N Golubev, A Karneyeu, M Kirsanov, N Krasnikov, A Pashenkov, D Tlisov, A Toropin, V Epshteyn, V Gavrilov, N Lychkovskaya, V Popov, I Pozdnyakov, G Safronov, A Spiridonov, A Stepennov, V Stolin, M Toms, E Vlasov, A Zhokin, T Aushev, A Bylinkin, R Chistov, M Danilov, P Parygin, D Philippov, S Polikarpov, E Tarkovskii, V Andreev, M Azarkin, I Dremin, M Kirakosyan, S V Rusakov, A Terkulov, A Baskakov, A Belyaev, E Boos, V Bunichev, M Dubinin, L Dudko, A Ershov, A Gribushin, V Klyukhin, O Kodolova, I Lokhtin, I Miagkov, S Obraztsov, S Petrushanko, V Savrin, V Blinov, T Dimova, L Kardapoltsev, D Shtol, Y Skovpen, I Azhgirey, I Bayshev, S Bitioukov, D Elumakhov, A Godizov, V Kachanov, A Kalinin, D Konstantinov, P Mandrik, V Petrov, R Ryutin, S Slabospitskii, A Sobol, S Troshin, N Tyurin, A Uzunian, A Volkov, A Babaev, P Adzic, P Cirkovic, D Devetak, M Dordevic, J Milosevic, J Alcaraz Maestre, A Álvarez Fernández, I Bachiller, M Barrio Luna, J A Brochero Cifuentes, M Cerrada, N Colino, B De La Cruz, A Delgado Peris, C Fernandez Bedoya, J P Fernández Ramos, J Flix, M C Fouz, O Gonzalez Lopez, S Goy Lopez, J M Hernandez, M I Josa, D Moran, A Pérez-Calero Yzquierdo, J Puerta Pelayo, I Redondo, L Romero, M S Soares, A Triossi, C Albajar, J F de Trocóniz, J Cuevas, C Erice, J Fernandez Menendez, S Folgueras, I Gonzalez Caballero, J R González Fernández, E Palencia Cortezon, S Sanchez Cruz, P Vischia, J M Vizan Garcia, I J Cabrillo, A Calderon, B Chazin Quero, J Duarte Campderros, M Fernandez, P J Fernández Manteca, A García Alonso, J Garcia-Ferrero, G Gomez, A Lopez Virto, J Marco, C Martinez Rivero, P Martinez Ruiz Del Arbol, F Matorras, J Piedra Gomez, C Prieels, T Rodrigo, A Ruiz-Jimeno, L Scodellaro, N Trevisani, I Vila, R Vilar Cortabitarte, D Abbaneo, B Akgun, E Auffray, P Baillon, A H Ball, D Barney, J Bendavid, M Bianco, A Bocci, C Botta, T Camporesi, M Cepeda, G Cerminara, E Chapon, Y Chen, G Cucciati, D d'Enterria, A Dabrowski, V Daponte, A David, A De Roeck, N Deelen, M Dobson, T du Pree, M Dünser, N Dupont, A Elliott-Peisert, P Everaerts, F Fallavollita, G Franzoni, J Fulcher, W Funk, D Gigi, A Gilbert, K Gill, F Glege, D Gulhan, J Hegeman, V Innocente, A Jafari, P Janot, O Karacheban, J Kieseler, V Knünz, A Kornmayer, M Krammer, C Lange, P Lecoq, C Lourenço, M T Lucchini, L Malgeri, M Mannelli, F Meijers, J A Merlin, S Mersi, E Meschi, P Milenovic, F Moortgat, M Mulders, H Neugebauer, J Ngadiuba, S Orfanelli, L Orsini, F Pantaleo, L Pape, E Perez, M Peruzzi, A Petrilli, G Petrucciani, A Pfeiffer, M Pierini, F M Pitters, D Rabady, A Racz, T Reis, G Rolandi, M Rovere, H Sakulin, C Schäfer, C Schwick, M Seidel, M Selvaggi, A Sharma, P Silva, P Sphicas, A Stakia, J Steggemann, M Tosi, D Treille, A Tsirou, V Veckalns, M Verweij, W D Zeuner, W Bertl, L Caminada, K Deiters, W Erdmann, R Horisberger, Q Ingram, H C Kaestli, D Kotlinski, U Langenegger, T Rohe, S A Wiederkehr, M Backhaus, L Bäni, P Berger, B Casal, N Chernyavskaya, G Dissertori, M Dittmar, M Donegà, C Dorfer, C Grab, C Heidegger, D Hits, J Hoss, T Klijnsma, W Lustermann, M Marionneau, M T Meinhard, D Meister, F Micheli, P Musella, F Nessi-Tedaldi, J Pata, F Pauss, G Perrin, L Perrozzi, M Quittnat, M Reichmann, D Ruini, D A Sanz Becerra, M Schönenberger, L Shchutska, V R Tavolaro, K Theofilatos, M L Vesterbacka Olsson, R Wallny, D H Zhu, T K Aarrestad, C Amsler, D Brzhechko, M F Canelli, A De Cosa, R Del Burgo, S Donato, C Galloni, T Hreus, B Kilminster, I Neutelings, D Pinna, G Rauco, P Robmann, D Salerno, K Schweiger, C Seitz, Y Takahashi, A Zucchetta, Y H Chang, K Y Cheng, T H Doan, Sh Jain, R Khurana, C M Kuo, W Lin, A Pozdnyakov, S S Yu, P Chang, Y Chao, K F Chen, P H Chen, W-S Hou, Arun Kumar, R-S Lu, E Paganis, A Psallidas, A Steen, J F Tsai, B Asavapibhop, N Srimanobhas, N Suwonjandee, A Bat, F Boran, S Cerci, S Damarseckin, Z S Demiroglu, C Dozen, I Dumanoglu, S Girgis, G Gokbulut, Y Guler, E Gurpinar, I Hos, E E Kangal, O Kara, A Kayis Topaksu, U Kiminsu, M Oglakci, G Onengut, K Ozdemir, S Ozturk, D Sunar Cerci, B Tali, U G Tok, S Turkcapar, I S Zorbakir, C Zorbilmez, B Isildak, G Karapinar, M Yalvac, M Zeyrek, I O Atakisi, E Gülmez, M Kaya, O Kaya, S Ozkorucuklu, S Tekten, E A Yetkin, M N Agaras, S Atay, A Cakir, K Cankocak, Y Komurcu, S Sen, B Grynyov, L Levchuk, T Alexander, F Ball, L Beck, J J Brooke, D Burns, E Clement, D Cussans, O Davignon, H Flacher, J Goldstein, G P Heath, H F Heath, L Kreczko, D M Newbold, S Paramesvaran, B Penning, T Sakuma, D Smith, V J Smith, J Taylor, K W Bell, A Belyaev, C Brew, R M Brown, D Cieri, D J A Cockerill, J A Coughlan, K Harder, S Harper, J Linacre, E Olaiya, D Petyt, C H Shepherd-Themistocleous, A Thea, I R Tomalin, T Williams, W J Womersley, G Auzinger, R Bainbridge, P Bloch, J Borg, S Breeze, O Buchmuller, A Bundock, S Casasso, D Colling, L Corpe, P Dauncey, G Davies, M Della Negra, R Di Maria, Y Haddad, G Hall, G Iles, T James, M Komm, C Laner, L Lyons, A-M Magnan, S Malik, A Martelli, J Nash, A Nikitenko, V Palladino, M Pesaresi, A Richards, A Rose, E Scott, C Seez, A Shtipliyski, G Singh, M Stoye, T Strebler, S Summers, A Tapper, K Uchida, T Virdee, N Wardle, D Winterbottom, J Wright, S C Zenz, J E Cole, P R Hobson, A Khan, P Kyberd, C K Mackay, A Morton, I D Reid, L Teodorescu, S Zahid, A Borzou, K Call, J Dittmann, K Hatakeyama, H Liu, C Madrid, B Mcmaster, N Pastika, C Smith, R Bartek, A Dominguez, A Buccilli, S I Cooper, C Henderson, P Rumerio, C West, D Arcaro, T Bose, D Gastler, D Rankin, C Richardson, J Rohlf, L Sulak, D Zou, G Benelli, X Coubez, D Cutts, M Hadley, J Hakala, U Heintz, J M Hogan, K H M Kwok, E Laird, G Landsberg, J Lee, Z Mao, M Narain, J Pazzini, S Piperov, S Sagir, R Syarif, D Yu, R Band, C Brainerd, R Breedon, D Burns, M Calderon De La Barca Sanchez, M Chertok, J Conway, R Conway, P T Cox, R Erbacher, C Flores, G Funk, W Ko, O Kukral, R Lander, C Mclean, M Mulhearn, D Pellett, J Pilot, S Shalhout, M Shi, D Stolp, D Taylor, K Tos, M Tripathi, Z Wang, F Zhang, M Bachtis, C Bravo, R Cousins, A Dasgupta, A Florent, J Hauser, M Ignatenko, N Mccoll, S Regnard, D Saltzberg, C Schnaible, V Valuev, E Bouvier, K Burt, R Clare, J W Gary, S M A Ghiasi Shirazi, G Hanson, G Karapostoli, E Kennedy, F Lacroix, O R Long, M Olmedo Negrete, M I Paneva, W Si, L Wang, H Wei, S Wimpenny, B R Yates, J G Branson, S Cittolin, M Derdzinski, R Gerosa, D Gilbert, B Hashemi, A Holzner, D Klein, G Kole, V Krutelyov, J Letts, M Masciovecchio, D Olivito, S Padhi, M Pieri, M Sani, V Sharma, S Simon, M Tadel, A Vartak, S Wasserbaech, J Wood, F Würthwein, A Yagil, G Zevi Della Porta, N Amin, R Bhandari, J Bradmiller-Feld, C Campagnari, M Citron, A Dishaw, V Dutta, M Franco Sevilla, L Gouskos, R Heller, J Incandela, A Ovcharova, H Qu, J Richman, D Stuart, I Suarez, S Wang, J Yoo, D Anderson, A Bornheim, J Bunn, J M Lawhorn, H B Newman, T Q Nguyen, M Spiropulu, J R Vlimant, R Wilkinson, S Xie, Z Zhang, R Y Zhu, M B Andrews, T Ferguson, T Mudholkar, M Paulini, M Sun, I Vorobiev, M Weinberg, J P Cumalat, W T Ford, F Jensen, A Johnson, M Krohn, S Leontsinis, E MacDonald, T Mulholland, K Stenson, K A Ulmer, S R Wagner, J Alexander, J Chaves, Y Cheng, J Chu, A Datta, K Mcdermott, N Mirman, J R Patterson, D Quach, A Rinkevicius, A Ryd, L Skinnari, L Soffi, S M Tan, Z Tao, J Thom, J Tucker, P Wittich, M Zientek, S Abdullin, M Albrow, M Alyari, G Apollinari, A Apresyan, A Apyan, S Banerjee, L A T Bauerdick, A Beretvas, J Berryhill, P C Bhat, G Bolla, K Burkett, J N Butler, A Canepa, G B Cerati, H W K Cheung, F Chlebana, M Cremonesi, J Duarte, V D Elvira, J Freeman, Z Gecse, E Gottschalk, L Gray, D Green, S Grünendahl, O Gutsche, J Hanlon, R M Harris, S Hasegawa, J Hirschauer, Z Hu, B Jayatilaka, S Jindariani, M Johnson, U Joshi, B Klima, M J Kortelainen, B Kreis, S Lammel, D Lincoln, R Lipton, M Liu, T Liu, J Lykken, K Maeshima, N Magini, J M Marraffino, D Mason, P McBride, P Merkel, S Mrenna, S Nahn, V O'Dell, K Pedro, C Pena, O Prokofyev, G Rakness, L Ristori, A Savoy-Navarro, B Schneider, E Sexton-Kennedy, A Soha, W J Spalding, L Spiegel, S Stoynev, J Strait, N Strobbe, L Taylor, S Tkaczyk, N V Tran, L Uplegger, E W Vaandering, C Vernieri, M Verzocchi, R Vidal, M Wang, H A Weber, A Whitbeck, D Acosta, P Avery, P Bortignon, D Bourilkov, A Brinkerhoff, L Cadamuro, A Carnes, M Carver, D Curry, R D Field, S V Gleyzer, B M Joshi, J Konigsberg, A Korytov, P Ma, K Matchev, H Mei, G Mitselmakher, K Shi, D Sperka, L Thomas, J Wang, S Wang, Y R Joshi, S Linn, A Ackert, T Adams, A Askew, S Hagopian, V Hagopian, K F Johnson, T Kolberg, G Martinez, T Perry, H Prosper, A Saha, A Santra, V Sharma, R Yohay, M M Baarmand, V Bhopatkar, S Colafranceschi, M Hohlmann, D Noonan, T Roy, F Yumiceva, M R Adams, L Apanasevich, D Berry, R R Betts, R Cavanaugh, X Chen, S Dittmer, O Evdokimov, C E Gerber, D A Hangal, D J Hofman, K Jung, J Kamin, C Mills, I D Sandoval Gonzalez, M B Tonjes, N Varelas, H Wang, Z Wu, J Zhang, M Alhusseini, B Bilki, W Clarida, K Dilsiz, S Durgut, R P Gandrajula, M Haytmyradov, V Khristenko, J-P Merlo, A Mestvirishvili, A Moeller, J Nachtman, H Ogul, Y Onel, F Ozok, A Penzo, C Snyder, E Tiras, J Wetzel, B Blumenfeld, A Cocoros, N Eminizer, D Fehling, L Feng, A V Gritsan, W T Hung, P Maksimovic, J Roskes, U Sarica, M Swartz, M Xiao, C You, A Al-Bataineh, P Baringer, A Bean, S Boren, J Bowen, J Castle, S Khalil, A Kropivnitskaya, D Majumder, W Mcbrayer, M Murray, C Rogan, S Sanders, E Schmitz, J D Tapia Takaki, Q Wang, A Ivanov, K Kaadze, Y Maravin, A Modak, A Mohammadi, L K Saini, N Skhirtladze, F Rebassoo, D Wright, A Baden, O Baron, A Belloni, S C Eno, Y Feng, C Ferraioli, N J Hadley, S Jabeen, G Y Jeng, R G Kellogg, J Kunkle, A C Mignerey, F Ricci-Tam, Y H Shin, A Skuja, S C Tonwar, K Wong, D Abercrombie, B Allen, V Azzolini, R Barbieri, A Baty, G Bauer, R Bi, S Brandt, W Busza, I A Cali, M D'Alfonso, Z Demiragli, G Gomez Ceballos, M Goncharov, P Harris, D Hsu, M Hu, Y Iiyama, G M Innocenti, M Klute, D Kovalskyi, Y-J Lee, A Levin, P D Luckey, B Maier, A C Marini, C Mcginn, C Mironov, S Narayanan, X Niu, C Paus, C Roland, G Roland, G S F Stephans, K Sumorok, K Tatar, D Velicanu, J Wang, T W Wang, B Wyslouch, S Zhaozhong, A C Benvenuti, R M Chatterjee, A Evans, P Hansen, S Kalafut, Y Kubota, Z Lesko, J Mans, S Nourbakhsh, N Ruckstuhl, R Rusack, J Turkewitz, M A Wadud, J G Acosta, S Oliveros, E Avdeeva, K Bloom, D R Claes, C Fangmeier, F Golf, R Gonzalez Suarez, R Kamalieddin, I Kravchenko, J Monroy, J E Siado, G R Snow, B Stieger, A Godshalk, C Harrington, I Iashvili, A Kharchilava, D Nguyen, A Parker, S Rappoccio, B Roozbahani, G Alverson, E Barberis, C Freer, A Hortiangtham, A Massironi, D M Morse, T Orimoto, R Teixeira De Lima, T Wamorkar, B Wang, A Wisecarver, D Wood, S Bhattacharya, O Charaf, K A Hahn, N Mucia, N Odell, M H Schmitt, K Sung, M Trovato, M Velasco, R Bucci, N Dev, M Hildreth, K Hurtado Anampa, C Jessop, D J Karmgard, N Kellams, K Lannon, W Li, N Loukas, N Marinelli, F Meng, C Mueller, Y Musienko, M Planer, A Reinsvold, R Ruchti, P Siddireddy, G Smith, S Taroni, M Wayne, A Wightman, M Wolf, A Woodard, J Alimena, L Antonelli, B Bylsma, L S Durkin, S Flowers, B Francis, A Hart, C Hill, W Ji, T Y Ling, W Luo, B L Winer, H W Wulsin, S Cooperstein, P Elmer, J Hardenbrook, P Hebda, S Higginbotham, A Kalogeropoulos, D Lange, J Luo, D Marlow, K Mei, I Ojalvo, J Olsen, C Palmer, P Piroué, J Salfeld-Nebgen, D Stickland, C Tully, S Malik, S Norberg, A Barker, V E Barnes, S Das, L Gutay, M Jones, A W Jung, A Khatiwada, D H Miller, N Neumeister, C C Peng, H Qiu, J F Schulte, J Sun, F Wang, R Xiao, W Xie, T Cheng, J Dolen, N Parashar, Z Chen, K M Ecklund, S Freed, F J M Geurts, M Guilbaud, M Kilpatrick, W Li, B Michlin, B P Padley, J Roberts, J Rorie, W Shi, Z Tu, J Zabel, A Zhang, A Bodek, P de Barbaro, R Demina, Y T Duh, J L Dulemba, C Fallon, T Ferbel, M Galanti, A Garcia-Bellido, J Han, O Hindrichs, A Khukhunaishvili, K H Lo, P Tan, R Taus, M Verzetti, A Agapitos, J P Chou, Y Gershtein, T A Gómez Espinosa, E Halkiadakis, M Heindl, E Hughes, S Kaplan, R Kunnawalkam Elayavalli, S Kyriacou, A Lath, R Montalvo, K Nash, M Osherson, H Saka, S Salur, S Schnetzer, D Sheffield, S Somalwar, R Stone, S Thomas, P Thomassen, M Walker, A G Delannoy, J Heideman, G Riley, K Rose, S Spanier, K Thapa, O Bouhali, A Castaneda Hernandez, A Celik, M Dalchenko, M De Mattia, A Delgado, S Dildick, R Eusebi, J Gilmore, T Huang, T Kamon, R Mueller, Y Pakhotin, R Patel, A Perloff, L Perniè, D Rathjens, A Safonov, A Tatarinov, N Akchurin, J Damgov, F De Guio, P R Dudero, J Faulkner, S Kunori, K Lamichhane, S W Lee, T Mengke, S Muthumuni, T Peltola, S Undleeb, I Volobouev, Z Wang, S Greene, A Gurrola, R Janjam, W Johns, C Maguire, A Melo, H Ni, K Padeken, J D Ruiz Alvarez, P Sheldon, S Tuo, J Velkovska, Q Xu, M W Arenton, P Barria, B Cox, R Hirosky, M Joyce, A Ledovskoy, H Li, C Neu, T Sinthuprasith, Y Wang, E Wolfe, F Xia, R Harr, P E Karchin, N Poudyal, J Sturdy, P Thapa, S Zaleski, M Brodski, J Buchanan, C Caillol, D Carlsmith, S Dasu, L Dodd, S Duric, B Gomber, M Grothe, M Herndon, A Hervé, U Hussain, P Klabbers, A Lanaro, A Levine, K Long, R Loveless, T Ruggles, A Savin, N Smith, W H Smith, N Woods
A search for the Higgs boson decaying to two oppositely charged muons is presented using data recorded by the CMS experiment at the CERN LHC in 2016 at a center-of-mass energy sqrt[s]=13  TeV, corresponding to an integrated luminosity of 35.9  fb^{-1}. Data are found to be compatible with the predicted background. For a Higgs boson with a mass of 125.09 GeV, the 95% confidence level observed (background-only expected) upper limit on the production cross section times the branching fraction to a pair of muons is found to be 3...
January 18, 2019: Physical Review Letters
https://read.qxmd.com/read/30716975/characterization-of-the-macromolecular-and-sensory-profile-of-non-alcoholic-beers-produced-with-various-methods
#11
Georg Krebs, Magdalena Müller, Thomas Becker, Martina Gastl
Due to changing consumer habits, non-alcoholic beer is the fastest-growing market within the beverage industry. Different processing technologies for limiting the alcohol content of beer yield in completely different matrix compositions and sensory profiles. Especially the specific sensory attributes of palate fullness, mouthfeel, and the perception of harmony (ratio harmony between sweetness and sourness) of non-alcoholic beers are often described as atypical and unbalanced by the consumer. In addition to technological aspects, the matrix components represent a significant factor...
February 2019: Food Research International
https://read.qxmd.com/read/30712565/absolute-molar-mass-determination-in-mixed-solvents-1-solving-for-the-sec-mals-dri-trivial-case
#12
André M Striegel, Pritish Sinha
Size-exclusion chromatography (SEC) with on-line static light scattering, specifically multi-angle static light scattering (MALS), and differential refractometry (DRI) detection remains the premier method by which to determine absolute, calibrant-independent molar masses of polymers. The method is restricted to the use of either neat solvents or solvents with a small amount of additive. In mixed solvents, preferential solvation (i.e., the enrichment, within the solvated volume of the polymer in solution, of one solvent over the other as compared to the solvent ratio outside said volume) leads to errors in the areas of the MALS and DRI chromatograms, as the solvent baseline does not accurately represent the solvent contribution to these detectors' peaks...
April 11, 2019: Analytica Chimica Acta
https://read.qxmd.com/read/30711472/shedding-light-on-the-effects-of-1-25-dihydroxyvitamin-d-3-on-epidermal-lipid-barrier-formation-in-three-dimensional-human-skin-equivalents
#13
Arnout Mieremet, Rianne van Dijk, Gert Gooris, Joke A Bouwstra, Abdoelwaheb El Ghalbzouri
Human skin equivalents (HSEs) are three dimensional models resembling native human skin (NHS) in many aspects. Despite the manifold similarities to NHS, a restriction in its applications is the altered in vitro lipid barrier formation, which compromises the barrier functionality. This could be induced by suboptimal cell culturing conditions, which amongst others is the diminished activation of the vitamin D receptor (VDR) signalling pathway. The active metabolite of this signalling pathway is 1,25-dihydroxyvitamin D3 (1,25(OH)2 D3 )...
January 31, 2019: Journal of Steroid Biochemistry and Molecular Biology
https://read.qxmd.com/read/30710711/patterning-of-human-epidermal-stem-cells-on-undulating-elastomer-substrates-reflects-differences-in-cell-stiffness
#14
Seyedeh Atefeh Mobasseri, Sebastiaan Zijl, Vasiliki Salameti, Gernot Walko, Andrew Stannard, Sergi Garcia-Manyes, Fiona M Watt
In human skin the junction between epidermis and dermis undulates, the width and depth of the undulations varying with age and disease. When primary human epidermal keratinocytes are seeded on collagen-coated polydimethylsiloxane (PDMS) elastomer substrates that mimic the epidermal-dermal interface, the stem cells become patterned by 24 h, resembling their organisation in living skin. We found that cell density and nuclear height were higher at the base than the tips of the PDMS features. Cells on the tips not only expressed higher levels of the stem cell marker β1 integrin but also had elevated E-cadherin, Desmoglein 3 and F-actin than cells at the base...
January 30, 2019: Acta Biomaterialia
https://read.qxmd.com/read/30710188/an-imidazo-1-5-%C3%AE-pyridine-based-fluorometric-chemodosimeter-for-the-highly-selective-detection-of-hypochlorite-in-aqueous-media
#15
Suh Mi Hwang, Dongju Yun, Cheal Kim
A new fluorometric chemodosimeter 2-amino-3-(((E)-3-(1-phenylimidazo[1,5-α]pyridin-3-yl)benzylidene)amino)maleonitrile (BPI-MAL) has been designed and synthesized for sensing hypochlorite. BPI-MAL showed a selective turn-on fluorescence for ClO- through hypochlorite-promoted de-diaminomaleonitrile reaction. It also could detect ClO- in the presence of various competitive anions including reactive oxygen species. Interestingly, sensor BPI-MAL was successfully applied as a fluorescent test kit for ClO- determination...
February 2, 2019: Journal of Fluorescence
https://read.qxmd.com/read/30709335/invasion-triple-trouble-environmental-fluctuations-fluctuation-adapted-invaders-and-fluctuation-mal-adapted-communities-all-govern-invasion-success
#16
Kati Saarinen, Leena Lindström, Tarmo Ketola
BACKGROUND: It has been suggested that climate change will lead to increased environmental fluctuations, which will undoubtedly have evolutionary consequences for all biota. For instance, fluctuations can directly increase the risk of invasions of alien species into new areas, as these species have repeatedly been proposed to benefit from disturbances. At the same time increased environmental fluctuations may also select for better invaders. However, selection by fluctuations may also influence the resistance of communities to invasions, which has rarely been tested...
February 1, 2019: BMC Evolutionary Biology
https://read.qxmd.com/read/30708967/the-history-of-armand-trousseau-and-cancer-associated-thrombosis
#17
EDITORIAL
Pat Metharom, Marco Falasca, Michael C Berndt
"Je suis perdu; une phlegmatia qui vient de se déclarer cette nuit, ne me laisse aucun doute sur nature de mon mal [...] .
January 31, 2019: Cancers
https://read.qxmd.com/read/30706728/a-two-gene-methylation-signature-for-the-diagnosis-of-bladder-cancer-in-urine
#18
Judith Bosschieter, Jakko A Nieuwenhuijzen, Anouk Hentschel, Annina P van Splunter, Loes I Segerink, André N Vis, Saskia M Wilting, Birgit I Lissenberg-Witte, R Jeroen A van Moorselaar, Renske Dm Steenbergen
AIM: To analyze the potential of 14 cancer-associated genes, including six miRNAs, for bladder cancer (BC) diagnosis in urine. PATIENTS & METHODS: DNA methylation levels of 14 genes were analyzed in urine of 72 BC patients and 75 healthy controls using quantitative methylation-specific PCR. Multivariate logistic regression analysis was used to determine an optimal marker panel. RESULTS: Ten genes were significantly hypermethylated in BC patients...
February 1, 2019: Epigenomics
https://read.qxmd.com/read/30706355/in-vivo-effect-of-bis-maltolato-zinc-ii-complex-on-akt-phosphorylation-in-adipose-tissues-of-mice
#19
Yuki Naito, Hiroaki Yamamoto, Yutaka Yoshikawa, Hiroyuki Yasui
The risk of serious complication gradually increases as diabetes mellitus (DM) progresses. Thus, strategies for the prevention and delay of symptom progression are urgently needed. Previously, we synthesized zinc (Zn) complexes estimated to have a high bioavailability and evaluated their insulin-like anti-DM effects. However, in vivo studies of the effects of Zn compounds on the insulin signaling pathway and the molecular mechanisms underlying the anti-diabetic activities of Zn complexes were unresolved. In this study, we evaluated the effect of bis(maltolato)zinc(II) complex [Zn(mal)2 ] on male ICR mice (6-week-old) that received intraperitoneal (i...
January 31, 2019: Biological Trace Element Research
https://read.qxmd.com/read/30705578/fabrication-of-maxillary-single-complete-denture-in-a-patient-with-deranged-mandibular-occlusal-plane-a-case-report
#20
Kam Wah Foong, Pravinkumar G Patil
Construction of a single complete denture (SCD) is a challenging clinical situation especially when the opposing natural dentition is not in a normal plane of occlusion. Mal-aligned, tilted or supra-erupted teeth in the opposing arch are some of the problems that should be corrected to achieve a balanced occlusion in patients who require SCD. Achieving harmonious occlusal plane is a primary objective of any restorative procedure to facilitate natural mandibular movements and ease of mastication. Establishment of normal occlusal plane in opposite arch is pre-requisite to maintain the stability of the SCD...
January 2019: Saudi Dental Journal
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