Ines Schoberleitner, Leoni Baier, Michaela Lackner, Lisa-Maria Zenz, Débora C Coraça-Huber, Wendy Ullmer, Annabelle Damerum, Klaus Faserl, Stephan Sigl, Theresia Steinkellner, Selina Winkelmann, Bettina Sarg, Daniel Egle, Christine Brunner, Dolores Wolfram
Breast cancer is the most common cancer in women globally, often necessitating mastectomy and subsequent breast reconstruction. Silicone mammary implants (SMIs) play a pivotal role in breast reconstruction, yet their interaction with the host immune system and microbiome remains poorly understood. This study investigates the impact of SMI surface topography on host antimicrobial responses, wound proteome dynamics, and microbial colonization. Biological samples were collected from ten human patients undergoing breast reconstruction with SMIs...
March 9, 2024: International Journal of Molecular Sciences