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Hair And Reconstruction

Bilgen Fatma, Ural Alper, Bekerecioglu Mehmet
Vascular anomalies are a group of lesions originating from blood vessels and lymphatics with varying histology and clinical behavior. They form the most common congenital anomalies in infants and children. The reconstructive method for the facial region defects varies depending on the size and position of the defect, as well as the patient's age, health status and aesthetic concerns. In this case, the authors present a male patient who underwent a wide resection of his mustache area because of vascular malformation and reconstructed with hair-bearing temporal artery island flap...
March 6, 2019: Journal of Craniofacial Surgery
Jong Sung Kim, Yu Seob Shin, Jong Kwan Park
Purpose: Penile resurfacing with various scrotal flaps is a simple, effective, and reliable reconstructive armamentarium to treat penile paraffinoma. However, scrotal flaps often result in heavy hair-bearing penile skin causing dyspareunia or shortening of penile length. We introduce a new penile skin preservation technique for reconstruction surgery of penile paraffinoma. Materials and Methods: From March 2007 to April 2018, 23 patients underwent excision of paraffinoma with the penile skin preservation technique...
March 2019: Investigative and Clinical Urology
David Wilby, Tobio Aarts, Pierre Tichit, Andrew Bodey, Christoph Rau, Gavin Taylor, Emily Baird
Many insects have triplets of camera type eyes, called ocelli, whose function remains unclear for most species. Here, we investigate the ocelli of the bumblebee, Bombus terrestris, using reconstructed 3D data from X-ray micro computed-tomography scans combined with computational ray-tracing simulations. This method enables us, not only to predict the visual fields of the ocelli, but to explore for the first time the effect that hair has on them as well as the difference between worker female and male ocelli...
February 28, 2019: Vision Research
Janna Frombach, Michael Unbehauen, Indah N Kurniasih, Fabian Schumacher, Pierre Volz, Sabrina Hadam, Fiorenza Rancan, Ulrike Blume-Peytavi, Burkhard Kleuser, Rainer Haag, Ulrike Alexiev, Annika Vogt
In reconstructed skin and diffusion cell studies, core-multishell nanocarriers (CMS-NC) showed great potential for drug delivery across the skin barrier. Herein, we investigated penetration, release of dexamethasone (DXM), in excised full-thickness human skin with special focus on hair follicles (HF). Four hours and 16 h after topical application of clinically relevant dosages of 10 μg DXM/cm2 skin encapsulated in CMS-NC (12 nm diameter, 5.8% loading), presence of DXM in the tissue as assessed by fluorescence microscopy of anti-DXM-stained tissue sections as well as ELISA and HPLC-MS/MS in tissue extracts was enhanced compared to standard LAW-creme but lower compared to DXM aqueous/alcoholic solution...
February 21, 2019: Journal of Controlled Release: Official Journal of the Controlled Release Society
Ying Tang, Wendan He, Yanping Wu, Rui Cai
BACKGROUND: The interest toward dyeing hairs with plant colorants has grown in popularity considering its low-toxic nature. However, researches reporting plant hair dyes are limited and the potential adverse effects of irritation are unclear. OBJECTIVES: This study is aimed to provide an avenue by which to more accurately assess the dyeing efficiency and irritation potentials of plant hair dyes. METHODS: Four extracted plant colorants were incorporated in hydrogel hair dyes that were directly applied on unbleached gray human hairs...
February 18, 2019: Journal of Cosmetic Dermatology
Ahmed Khalaf Ali, Adamu Abdul Abubakar, Ubedullah Kaka, Zamri Radzi, Nurul Hayah Khairuddin, Md Sabri Mohd Yusoff, Mohamad Yusof Loqman
Aim: Tissue expansion is an applicable technique to reconstruct many surgical defects. The aim of this research was to evaluate the histological changes caused by immediate skin tissue expansion in rats as an animal model. Materials and Methods: Immediate skin tissue expansion in 18 adult female rats was performed using three different sizes (small, medium, and big) of polymethylmethacrylate tissue expanders at the dorsal surface of the metatarsal area of the right limb...
December 2018: Veterinary World
Geraint J Parfitt
Immunofluorescence tomography is a high-resolution 3-D reconstruction method based on methacrylate embedding and serial-sectioning, where 2-D images of immuno-stained serial-sections are computationally aligned into image stacks, and the 3-D volume rendered. Butyl-Methyl Methacrylate (BMMA) plastic was adopted as it preserves excellent tissue morphology and can be de-plasticized easily using an organic solvent, which enables immuno-staining of serial-sections without antibody penetration issues over millimeters of 3-D reconstructed tissue (Z-depth)...
February 13, 2019: Scientific Reports
C B Cannata, R De Rosa, P Donato, S Donato, G Lanzafame, L Mancini, B F Houghton
In this work the morphologic features of Pele's hair formed during three different eruptions of Kilauea volcano have been investigated: fountaining from Kilauea Iki's 1959 Episode 1, weak explosive activity from Halemaumau lava lake and littoral explosions at Waikupanaha (2009). Morphological studies were performed by optical, stereo- and scanning electron microscopy. For the first time 3D image analysis was carried out by synchrotron radiation X-ray computed microtomography, which allowed a high-resolution 3D reconstruction of the internal structure of each Pele's hair, highlighting several differences in terms of number density, elongation and shape of the vesicles between the samples from the three eruptions...
February 8, 2019: Scientific Reports
Philippe Charlier, Philippe Froesch, Nadia Benmoussa, Stéphane Morin, Anaïs Augias, Yves Ubelmann, Raphaël Weil, Soizic Morin, François Straub, Saudamini Deo
The supposed relics of "Mary-Magdalene" are preserved in Provence (France) in an ancient tradition. They consist of a dry skull and a lock of hair. For the first time, they were officially subjected to an extensive medico-surgical examination by photogrammetry, high-magnification binocular lenses, scanning electron microscope, and energy-dispersive X-ray elemental analysis, to propose a full computer-aided facial reconstruction. The preliminary results are presented here.
2019: Clinical Medicine Insights. Ear, Nose and Throat
Yuanyuan Zheng, Zeying Wang, Yubo Zhu, Wei Wang, Man Bai, Qian Jiao, Yanru Wang, Sujun Zhao, Xianbo Yin, Dan Guo, Wenlin Bai
Long noncoding RNAs (lncRNAs), a class of non-protein conding RNAs > 200 nt in length, were thought to play critical roles in regulating the expression of protein-coding genes. Here, we identified and characterized a novel lncRNA-000133 from the secondary hair follicle (SHF) of cashmere goat with its ceRNA network analysis, as well as, its potential effects on inductive property of dermal papilla cells were evaluated through overexpression analysis. Expression analysis indicated that lncRNA-000133 had a significantly higher expression at anagen than that at telogen in SHF of Cashmere goat, suggesting that lncRNA-000133 might be involved in the reconstruction of SHF with the formation and growth of cashmere fiber...
January 11, 2019: Animal Biotechnology
Daniel Pitt, Michael W Bruford, Mario Barbato, Pablo Orozco-terWengel, Rodrigo Martínez, Natalia Sevane
The introduction of Iberian cattle in the Americas after Columbus' arrival imposed high selection pressures on a limited number of animals over a brief period of time. Knowledge of the genomic regions selected during this process may help in enhancing climatic resilience and sustainable animal production. We first determined taurine and indicine contributions to the genomic structure of modern Creole cattle. Second, we inferred their demographic history using approximate Bayesian computation (ABC), linkage disequilibrium (LD) and N e Slope (NeS) analysis...
January 2019: Evolutionary Applications
Antonio Scarano, Felice Lorusso, Alessandro Di Cerbo, Alberta Greco Lucchina, Francesco Carinci
OBJECTIVES: Vascularized soft tissue flaps are often harvested from hair-bearing areas, such as the radial forearm or anterolateral thigh, making their use in oral reconstruction problematic due to postoperative hair growth. The presence of intact hair follicles in free tissue transfer and continued hair growth at the recipient site can result in difficulties with oral hygiene, intraoral irritation, food trapping, and patient distress. This study was to evaluate the intraoral efficacy and safety of a diode laser 808 nm when used for hair removal...
January 6, 2019: Lasers in Surgery and Medicine
Joon Seok Lee, Joon Hyun Kwon, Gyu Sik Jung, Jeong Woo Lee, Jung Dug Yang, Ho Yun Chung, Byung Chae Cho, Kang Young Choi
Trichoblastic carcinoma usually occurs as a malignant transformation of the trichoblastoma, but is very rare. A 25-year-old man was admitted with trichoblastoma in the nuchal area with frequent recurrences since birth. The preoperative neck magnetic resonance image revealed lobulated soft tissue lesions involving superficial fascia and infiltrating into both proximal trapezius muscles. In our department, wide excision and reconstruction with a free anterolateral thigh flap were performed. Histological examination revealed skin adnexal carcinoma, originating from the hair follicles, consistent with trichoblastic carcinoma...
December 2018: Archives of Craniofacial Surgery
Chao Zhong, Yong Fu, Wen Pan, Jun Yu, Jinfu Wang
Damage or loss of auditory hair cells leads to irreversible sensorineural hearing loss in human, thus regeneration of these cells to reconstruct auditory sensory epithelium holds the promise for the treatment of deafness. Regulatory factors involved in the development of auditory sensory epithelium play crucial roles in hair cell regeneration and hearing restoration. Here, we first focus on the transcription factor Atoh1 which is critical for hair cell development and regeneration, and comprehensively summarize the current understanding of the protein structure, target binding motif, developmental expression pattern, functional role, and upstream and downstream regulatory mechanism of Atoh1 in the context of controlling the cell fate commitment to hair cells or transdifferentiation from supporting cells...
February 15, 2019: Developmental Biology
Songjia Tang, Xiaoxin Wu, Zhongxin Sun, Hanxiao Cheng, Haiyan Shen, Liang Tang, Jinghe Zhou, Ming Jia, Jinsheng Li, Jufang Zhang
For extensive irregular cicatricial alopecia after burn, effective and pleasing restoration of hair-bearing scalp remains challenging. In this article, the authors presented staged reconstructive treatment for extensive irregular cicatricial alopecia with the goal to achieve better and reliable results. A retrospective review of staged reconstructive treatment performed in 16 patients with extensive irregular cicatricial alopecia after burn was conducted. In stage 1, final flaps were designed at 1st. Tissue expanders were placed into the subgaleal plane and serially inflated with normal saline...
December 2018: Medicine (Baltimore)
Maria Gabriela Cuezzo, Maria Jose Miranda, Roberto Eugenio Vogler, Ariel Anibal Beltramino
Background: Land gastropods of the Dry Chaco merit special attention because they comprise a highly diverse but barely studied group. Clessinia Doering, 1875 are typical inhabitants of this ecoregion. The inclusion of their distribution areas into Spixia range, their shell shape similarities, and a former molecular study raised doubts on the monophyly of this genus. The present study review the species of Clessinia , under a morphological, geometric morphometrics, and molecular combined approach...
2018: PeerJ
Qian Jiao, Rong H Yin, Su J Zhao, Ze Y Wang, Yu B Zhu, Wei Wang, Yuan Y Zheng, Xian B Yin, Dan Guo, Shi Q Wang, Yan X Zhu, Wen L Bai
The HOTAIR transcript is transcribed from the antisense strand within the HOXC gene cluster, and it is thought to play a role in regulating the inductive capacity of dermal papilla cells during the reconstruction of hair-follicle. In the current investigation, we firstly isolated and characterized a lncRNA-HOTAIR transcript from the secondary hair follicle of cashmere goat. Also, we analyzed its transcriptional pattern and methylation level of HOTAIR gene promoter in secondary hair follicle of cashmere goat during anagen and telogen stages...
December 3, 2018: Gene
Satyaswarup Tripathy, Akhil Garg, Jerry R John, Ramesh Kumar Sharma
The paramedian forehead flap is a workhorse flap for reconstructing the nose and periorbital regions. Many variants are described including an islanded flap. However, eyebrow reconstruction is not usually performed with these flaps. The authors describe a patient suffering from postburn scarring medial to the left eye, including loss of the left eyebrow. He underwent a single-stage transfer of the paramedian forehead flap. The flap incorporated scalp hair, which restored the missing eyebrow hair after transfer...
November 30, 2018: Journal of Craniofacial Surgery
Jean P Boubli, Hazel Byrne, Maria N F da Silva, José Silva-Júnior, Rodrigo Costa Araújo, Fabrício Bertuol, Jonas Gonçalves, Fabiano Melo, Anthony B Rylands, Russell A Mittermeier, Felipe E Silva, Stephen D Nash, Gustavo Canale, Raony de M Alencar, Rogerio Rossi, Jeferson Carneiro, Iracilda Sampaio, Izeni P Farias, Horácio Schneider, Tomas Hrbek
The taxonomy of the titi monkeys (Callicebinae) has recently received considerable attention. It is now recognised that this subfamily is composed of three genera with 33 species, seven of them described since 2002. Here, we describe a new species of titi, Plecturocebus, from the municipality of Alta Floresta, Mato Grosso, Brazil. We adopt an integrative taxonomic approach that includes phylogenomic analyses, pelage characters, and locality records. A reduced representation genome-wide approach was employed to assess phylogenetic relationships among species of the eastern Amazonian clade of the Plecturocebus moloch group...
November 26, 2018: Molecular Phylogenetics and Evolution
Takeshi Yamauchi, Kenshi Yamasaki, Kenichiro Tsuchiyama, Setsuya Aiba
The skin composes physiological and chemical barrier and renews skin component cells throughout the human life. Melanocytes locate in the basal layer of the epidermis and produce melanin to protect the skin from ultraviolet. Melanin plays key roles in determining human skin and hair color. Melanocyte dysfunction observed in albinism and vitiligo not only causes cosmetic problems but also increases risk of skin cancer. As rejuvenate therapy, embryonic stem (ES) cells and induced pluripotent stem (iPS) cells have been reported to generate melanocytes...
2018: Advances in Experimental Medicine and Biology
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