keyword
https://read.qxmd.com/read/36374795/should-a-living-donor-renal-graft-be-removed-due-to-prolonged-delayed-function-a-case-report
#21
JOURNAL ARTICLE
Ahmed Salem Al-Thahir, Ali Abdullah Al-Yami, Emadeldeen Saeed, Rafat Zahid, Hamad Mohd Al-Bahili, Ioannis Theodoropoulos
BACKGROUND Delayed graft function (DGF) is defined as failure of the transplanted kidney to function in the early -post-transplant period. DGF is a rare complication after living donor kidney transplant and is most common after deceased donor kidney transplant, probably due to prolonged warm and cold ischemia times during retrieval. Most cases of DGF resolve spontaneously within days to weeks. There are very few reported cases in the literature of DGF lasting over 4 weeks. We present a case that resolved after 55 days...
November 14, 2022: American Journal of Case Reports
https://read.qxmd.com/read/36327753/high-dose-nitroglycerin-infusion-description-of-safety-and-efficacy-in-sympathetic-crashing-acute-pulmonary-edema-the-hi-dose-scape-study
#22
JOURNAL ARTICLE
Brandon S Houseman, Ashley N Martinelli, Wesley D Oliver, Sandeep Devabhakthuni, Amal Mattu
BACKGROUND: Sympathetic crashing acute pulmonary edema (SCAPE) is a medical emergency in which severe, acute elevation in blood pressure results in acute heart failure and fluid accumulation in the lungs. Without prompt recognition and treatment, the condition often progresses rapidly to respiratory failure necessitating intubation and intensive care unit (ICU) admission. In addition to non-invasive positive pressure ventilation (NIPPV), high-dose nitroglycerin (HDN) has become a mainstay of treatment; however, an optimal dosing strategy has not been established...
January 2023: American Journal of Emergency Medicine
https://read.qxmd.com/read/36168799/echocardiographic-changes-after-arteriovenous-fistula-creation-in-hemodialysis-patients
#23
JOURNAL ARTICLE
Karen Manzur-Pineda, Laisel Martinez, Roger Alvarez, Adriana Dejman, Roberto I Vazquez-Padron, Marwan Tabbara, Juan C Duque
BACKGROUND: Pulmonary hypertension (PH) is common in end-stage renal disease (ESRD) patients and is associated with increased all-cause and cardiovascular mortality in this group. There is scarce data on the long-term effect of arteriovenous fistula (AVF) creation on pulmonary hypertension (PH) and the reflected changes in echocardiographic measurements. MATERIALS AND METHODS: This is a retrospective study of 54 patients who underwent AVF creation between 2009 and 2014 and with echocardiographic evaluations before and after surgery...
November 2022: Clinical Nephrology
https://read.qxmd.com/read/36130612/long-term-outcomes-after-catheter-based-renal-artery-denervation-for-resistant-hypertension-final-follow-up-of-the-randomised-symplicity-htn-3-trial
#24
RANDOMIZED CONTROLLED TRIAL
Deepak L Bhatt, Muthiah Vaduganathan, David E Kandzari, Martin B Leon, Krishna Rocha-Singh, Raymond R Townsend, Barry T Katzen, Suzanne Oparil, Sandeep Brar, Vanessa DeBruin, Martin Fahy, George L Bakris
BACKGROUND: The SYMPLICITY HTN-3 (Renal Denervation in Patients With Uncontrolled Hypertension) trial showed the safety but not efficacy of the Symplicity system (Medtronic, Santa Rosa, CA, USA) at 6 months follow-up in patients with treatment-resistant hypertension. This final report presents the 36-month follow-up results. METHODS: SYMPLICITY HTN-3 was a single-blind, multicentre, sham-controlled, randomised clinical trial, done in 88 centres in the USA. Adults aged 18-80 years, with treatment-resistant hypertension on stable, maximally tolerated doses of three or more drugs including a diuretic, who had a seated office systolic blood pressure of 160 mm Hg or more and 24 h ambulatory systolic blood pressure of 135 mm Hg or more were randomly assigned (2:1) to receive renal artery denervation using the single electrode (Flex) catheter or a sham control...
October 22, 2022: Lancet
https://read.qxmd.com/read/36064690/cardio-renal-interaction-clinical-trials-update-2022
#25
REVIEW
Michael Kunz, Felix Götzinger, Insa Emrich, Vedat Schwenger, Michael Böhm, Felix Mahfoud
AIMS: Chronic kidney disease is a common cardiovascular risk indicator and strongly associated with increased morbidity and mortality. The heart and kidneys are pathophysiologically closely connected, which becomes particularly obvious in patients with cardiorenal syndrome. This review summarizes clinically relevant studies on the cardio-renal interaction published in 2021 and 2022. DATA SYNTHESIS: Selected trials published in high-impact journals were chosen from the database Pubmed and included in this review...
November 2022: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://read.qxmd.com/read/35811816/characteristics-and-risk-factors-of-infections-in-patients-with-hbv-related-acute-on-chronic-liver-failure-a-retrospective-study
#26
JOURNAL ARTICLE
Qian Zhang, Baoxian Shi, Liang Wu
Background: Acute-on-chronic liver failure (ACLF) is a syndrome characterized by acute decompensation, organ failures, and high short-term mortality whose main cause in China is the Hepatitis B virus (HBV). Moreover, one of the most important causes of morbidity and mortality in HBV-ACLF patients is bacterial infection. Therefore, we investigate the clinical features, risk factors, prophylaxis and management of infections in patients with HBV-ACLF. Methods: We conducted a retrospective analysis of 539 patients with HBV-ACLF in Wuhan Tongji Hospital from October 2015 to May 2018...
2022: PeerJ
https://read.qxmd.com/read/35535075/clinical-implications-evaluation-and-management-of-hyponatremia-in-cirrhosis
#27
REVIEW
Dibya L Praharaj, Anil C Anand
Hyponatremia is the most common electrolyte abnormality in patients with decompensated cirrhosis on Liver Transplantation (LT) waiting list. Most of these patients have dilutional or hypervolemic hyponatremia secondary to splanchnic vasodilatation. Excessive secretion of the antidiuretic hormone also plays an important role. Hypervolemic hyponatremia is commonly associated with refractory ascites, spontaneous bacterial peritonitis, and hepatic encephalopathy. Although uncommon, the use of diuretics and laxatives can cause hypovolemic hyponatremia that is characterized by the striking absence of ascites or pedal edema...
2022: Journal of Clinical and Experimental Hepatology
https://read.qxmd.com/read/35532709/nephrotic-syndrome-in-elderly-etiologies-management-and-prognosis
#28
JOURNAL ARTICLE
Imen Gorsane, Tasmime Ben Ayed, Meriam Hajji, Samia Barbouch, Taieb Ben Abdallah
The elderly population has significantly increased in the world. Nephrotic syndrome (NS) is one manifestation of glomerular nephropathy in the elderly. The objective of our study is to determine NS particularities in the elderly and to identify the factors predicting progression to chronic end-stage renal disease (ESRD). This is a retrospective and descriptive study, carried out between January 1, 1975 and December 31, 2017. It includes participants aged 65 years old or over hospitalized for NS. A multivariate study was carried out and the dependent variable was the evolution to ESRD...
2021: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/35465279/utilization-of-hospice-and-nonhospice-care-in-patients-with-end-stage-renal-disease-on-dialysis
#29
JOURNAL ARTICLE
Shu-Chen Wang, Kai-Chieh Hu, Wei-Chuan Chang, Chung-Y Hsu
Objectives: The prevalence of end-stage renal disease (ESRD) and the number of patients undergoing dialysis in Taiwan are high. Since September 2009, the National Health Insurance has started to provide hospice care to patients with renal failure in Taiwan. Therefore, it is necessary to understand the use of hospice and nonhospice care in patients with ESRD on dialysis. We aim to understand trends in patients with ESRD receiving hospice and nonhospice care as well as medical care efforts during the last month of their lives (2009-2013)...
April 2022: Tzu chi medical journal
https://read.qxmd.com/read/35439211/interdisciplinary-protocol-for-the-management-of-vision-threatening-papilledema
#30
JOURNAL ARTICLE
Taylor Brady, Sravanthi Vegunta, Alison V Crum, Douglas Marx, Bhupendra C K Patel, Meagan D Seay, Richard H Schmidt, Judith E A Warner, Kathleen B Digre, Bradley J Katz
BACKGROUND: This study evaluates the effectiveness of a multidisciplinary protocol for management of patients with papilledema and vision loss secondary to increased intracranial pressure. METHODS: Retrospective record review of all adult patients who presented with vision-threatening papilledema (VTPE) and were treated under this protocol. Patients are admitted for lumbar drain placement and diuretics and followed daily to determine if they may be managed medically or require surgery (optic nerve sheath fenestration [ONSF] and/or cerebrospinal fluid [CSF] shunting)...
December 1, 2022: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://read.qxmd.com/read/35105612/loop-and-thiazide-diuretic-use-and-risk-of-chronic-kidney-disease-progression-a-multicentre-observational-cohort-study
#31
MULTICENTER STUDY
Jesse K Fitzpatrick, Jingrong Yang, Andrew P Ambrosy, Claudia Cabrera, Bergur V Stefansson, Peter J Greasley, Jignesh Patel, Thida C Tan, Alan S Go
OBJECTIVES: To evaluate the association between diuretic use by class with chronic kidney disease (CKD) progression and onset of end-stage renal disease (ESRD). DESIGN: Retrospective cohort study. SETTING: Large integrated healthcare delivery system in Northern California. PARTICIPANTS: Adults with an estimated glomerular filtration rate (eGFR) 15-59 min/1.73 m2 by the CKD-Epidemiology Collaboration equation with no prior diuretic use...
January 31, 2022: BMJ Open
https://read.qxmd.com/read/35027714/prevalence-and-prognosis-of-refractory-hypertension-diagnosed-using-ambulatory-blood-pressure-measurements
#32
JOURNAL ARTICLE
Minjae Yoon, Seng Chan You, Jaewon Oh, Chan Joo Lee, Sang-Hak Lee, Seok-Min Kang, Sungha Park
The prognosis of refractory hypertension is largely unknown due to its low prevalence. This study aimed to investigate the prognosis of refractory hypertension and compare it with those of resistant and nonresistant hypertension. We retrospectively analyzed the data of 16,284 participants with hypertension who underwent ambulatory blood pressure (BP) monitoring between 2012 and 2019 at a tertiary center. Uncontrolled BP was defined as a 24-h BP ≥ 130/80 mmHg as assessed by ambulatory BP monitoring. Resistant hypertension was defined as uncontrolled BP despite the use of three antihypertensive medications, including a diuretic or the use of ≥4 drugs regardless of BP control...
August 2022: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://read.qxmd.com/read/34925865/sglt2-inhibition-in-patients-with-type-2-diabetes-mellitus-post-nephrectomy-a-single-center-case-series
#33
JOURNAL ARTICLE
Marko Škrtić, David Z I Cherney, Vikas S Sridhar, Christopher T M Chan, Abhijat Kitchlu
BACKGROUND: Nephrectomy is the mainstay of treatment for many kidney cancers, but has been correlated with increased incidence of acute kidney injury (AKI) and chronic kidney disease (CKD). Recently, sodium-glucose cotransporter-2 (SGLT2) inhibition has been shown to decrease the incidence of end-stage kidney disease and death in people with type 2 diabetes mellitus (T2D). However, at present, there has been no description of the use of SGLT2 inhibition in patients with T2D and solitary kidney despite the high risk of CKD progression...
2021: Canadian Journal of Kidney Health and Disease
https://read.qxmd.com/read/34922429/angiotensin-receptor-neprilysin-inhibitor-in-patients-with-heart-failure-and-chronic-kidney-disease
#34
JOURNAL ARTICLE
In-Jeong Cho, Seok-Min Kang
Despite significant advances in the management of heart failure with reduced ejection fraction (HFrEF), there remains an enormous health problem with high morbidity and mortality over the last few decades. The neprilysin inhibitor enhances the activity of natriuretic peptides, producing vasodilation, natriuresis, and diuresis. Angiotensin receptor blockers inhibit the renin-angiotensin-aldosterone system. Sacubitril/valsartan, a first-in-class angiotensin receptor-neprilysin inhibitor (ARNI), has been shown to improve cardiovascular outcomes in HFrEF and delay the progression of chronic kidney disease (CKD) in patients with HFrEF...
December 2021: Kidney Research and Clinical Practice
https://read.qxmd.com/read/34775702/-the-prevalence-influencing-factors-and-prognosis-of-abnormal-serum-potassium-levels-in-patients-with-chronic-kidney-disease
#35
JOURNAL ARTICLE
F Wang, C Yang, B X Gao, L X Zhang, M H Zhao, J W Wang
Objective: To estimate the prevalence of hyperkalemia and hypokalemia in patients with chronic kidney disease (CKD), analyze the influencing factors and explore the impact on disease prognosis. Methods: A total of 3 190 patients with CKD stage 1-4 from 39 tertiary clinical centers in China between November 2011 and December 2016 were recruited. The baseline characteristics of the patients were collected through face-to-face questionnaire investigation, physical examination and laboratory test. Meanwhile, the data of patient's end-stage renal disease, cardiovascular disease events and deaths were obtained up to December 2017 through active monitoring...
November 16, 2021: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://read.qxmd.com/read/34745667/recurrent-episodes-of-fluid-retention-in-a-patient-with-heart-failure-and-chronic-kidney-disease-the-additional-value-of-implantable-monitoring-systems
#36
Marc Vanderheyden, Sofie Verstreken, Richard Houben
The additional role of continuous monitoring of filling pressures and impedance in heart failure patients with chronic kidney disease remains undetermined. In this case report, the effects of diuretic therapy and renal replacement therapy by hemodialysis upon right ventricular filling pressures and impedance are described in a patient with end-stage heart failure and end-stage chronic kidney disease (grade 5). We demonstrated that unloading of the heart by hemodialysis partly restored the blunted Frank-Starling relationship...
2021: Case Reports in Cardiology
https://read.qxmd.com/read/34719384/covid-19-related-acute-kidney-injury-incidence-risk-factors-and-outcomes-in-a-large-uk-cohort
#37
JOURNAL ARTICLE
Paul D Jewell, Kate Bramham, James Galloway, Frank Post, Sam Norton, James Teo, Richard Fisher, Rohit Saha, Sam Hutchings, Phil Hopkins, Priscilla Smith, Jennifer Joslin, Satish Jayawardene, Sarah Mackie, Ali Mudhaffer, Amelia Holloway, Henry Kibble, Mosammat Akter, Benjamin Zuckerman, Kieran Palmer, Ciara Murphy, Domniki Iatropoulou, Claire C Sharpe, Eirini Lioudaki
BACKGROUND: Acute kidney injury (AKI) is common among patients hospitalised with COVID-19 and associated with worse prognosis. The aim of this study was to investigate the epidemiology, risk factors and outcomes of AKI in patients with COVID-19 in a large UK tertiary centre. METHODS: We analysed data of consecutive adults admitted with a laboratory-confirmed diagnosis of COVID-19 across two sites of a hospital in London, UK, from 1st January to 13th May 2020. RESULTS: Of the 1248 inpatients included, 487 (39%) experienced AKI (51% stage 1, 13% stage 2, and 36% stage 3)...
November 1, 2021: BMC Nephrology
https://read.qxmd.com/read/34510649/association-of-antihypertensives-during-hospitalization-with-acute-respiratory-failure-in-patients-with-viral-pneumonia-a-population-based-case-control-study
#38
JOURNAL ARTICLE
Shih-Yi Lin, Fung-Chang Sung, Cheng-Li Lin, Cheng-Chieh Lin, Wu-Huei Hsu, Wei-Chih Liao, Mao-Wang Ho, Po-Chang Lin, Chung-Y Hsu, Chia-Hung Kao
BACKGROUND: We aimed to identify associations between the risk of acute respiratory failure (ARF) and types of antihypertensive agents in patients with viral pneumonia. METHODS: In this case-control study, data extracted from the Taiwan National Health Insurance Research Database were analyzed. The base population comprised patients with viral pneumonia treated from 2000 to 2013. The case group comprised patients with ARF and the control group comprised participants without ARF...
September 12, 2021: International Journal of Clinical Practice
https://read.qxmd.com/read/34501446/persistent-resistant-hypertension-has-worse-renal-outcomes-in-chronic-kidney-disease-than-that-resolved-in-two-years-results-from-the-know-ckd-study
#39
JOURNAL ARTICLE
Su-Hyun Song, Young-Jin Kim, Hong-Sang Choi, Chang-Seong Kim, Eun-Hui Bae, Curie Ahn, Kook-Hwan Oh, Sue-Kyung Park, Kyu-Beck Lee, Suah Sung, Seung-Hyeok Han, Seong-Kwon Ma, Soo-Wan Kim
Apparent treatment-resistant hypertension (ATRH) is closely related to chronic kidney disease (CKD); however, the long-term outcomes and the effects of improvement in ATRH in patients with CKD are not well understood. We evaluated the relationship between the persistence of ATRH and the progression of CKD. This cohort study enrolled 1921 patients with CKD. ATRH was defined as blood pressure above 140/90 mmHg and intake of three different types of antihypertensive agents, including diuretics, or intake of four or more different types of antihypertensive agents, regardless of blood pressure...
September 3, 2021: Journal of Clinical Medicine
https://read.qxmd.com/read/34390334/determinants-and-outcomes-associated-with-urinary-calcium-excretion-in-chronic-kidney-disease
#40
MULTICENTER STUDY
Jing Liu, Maria Clarissa Tio, Ashish Verma, Insa M Schmidt, Titilayo O Ilori, Felix Knauf, Finnian R Mc Causland, Sushrut S Waikar
CONTEXT: Abnormalities in calcium metabolism are common in chronic kidney disease (CKD). Diminished urinary calcium excretion may promote vascular calcification and increased urinary calcium excretion may lead to nephrolithiasis and nephrocalcinosis, conditions associated with CKD. OBJECTIVE: To study predictors of urinary calcium excretion and its association with adverse clinical outcomes in CKD. DESIGN, SETTING AND PATIENTS: This study assessed 3768 nondialysis participants in the Chronic Renal Insufficiency Cohort study from April 2003 to September 2008...
January 1, 2022: Journal of Clinical Endocrinology and Metabolism
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