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Ophthalmology. Glaucoma

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https://read.qxmd.com/read/30771336/clinical-manifestations-prognosis-and-vaccination-status-of-patients-with-rubella-virus-associated-uveitis
#1
Fahriye Groen-Hakan, Suzanne van de Laar, Annemiek A van der Eijk-Baltissen, Ninette Ten Dam van Loon, Joke de Boer, Aniki Rothova
PURPOSE: To assess the clinical and laboratory manifestations and vaccination status of uveitis patients positive for Rubella virus (RV) in aqueous humor and investigate its relationship to Fuchs Uveitis Syndrome (FUS). METHODS: Retrospective study of all uveitis patients, positive for RV in aqueous humor analysis (polymerase chain reaction (PCR) and/or Goldmann-Witmer coefficient (GWC)) between January 2010 and October 2016 at the ophthalmology departments in the Erasmus Medical Center (Rotterdam) and University Medical Center Utrecht...
February 13, 2019: American Journal of Ophthalmology
https://read.qxmd.com/read/30758244/evaluation-of-antiglaucomatous-drops-on-conjunctival-thickness-in-patients-with-primary-open-angle-glaucoma
#2
Serek Tekin, Erbil Seven, Muhammed Batur
PURPOSE: To determine the effects of antiglaucomatous drops on the conjunctival thickness. METHODS: Between March 2018 and May 2018, conjunctival thicknesses (epithelium + stroma) were measured with anterior segment OCT in 51 eyes of the control group and 49 eyes who had glaucoma diagnosis at the Van YYU Medical Faculty Ophthalmology Department and had been using antiglaucomatous drops for at least 6 months. At 12 o'clock direction, horizontal multisections were taken aiming at the conjunctiva 3-5 mm away from the limbus...
February 13, 2019: Journal of Ocular Pharmacology and Therapeutics
https://read.qxmd.com/read/30755799/absence-of-posterior-vitreous-detachment-is-a-risk-factor-of-severe-bleb-related-endophthalmitis
#3
Kazuhiko Umazume, Jun Suzuki, Yoshihiko Usui, Katsuhiko Maruyama, Yoshihiro Wakabayashi, Hiroshi Goto
Purpose: Bleb-related endophthalmitis (BRE) after glaucoma surgery is an infection caused by bacteria in the avascular bleb gaining access into the eye. We report the clinical features and outcome of 10 consecutive eyes with severe BRE treated at our hospital. Methods: Ten patients (10 eyes) with stage IIIb BRE after trabeculectomy diagnosed and treated at the Department of Ophthalmology, Tokyo Medical University, between April 2013 and May 2015, were studied. Patient background, type of glaucoma, interval from the first trabeculectomy, pretreatment bleb findings, causative microorganisms, surgical methods, status of posterior vitreous detachment (PVD), and postoperative visual acuity were examined...
2019: Journal of Ophthalmology
https://read.qxmd.com/read/30720005/peripapillary-retinal-nerve-fiber-layer-thickness-in-patients-with-alzheimer-s-disease-a-comparison-of-eyes-of-patients-with-alzheimer-s-disease-primary-open-angle-glaucoma-and-preperimetric-glaucoma-and-healthy-controls
#4
Przemysław Zabel, Jakub J Kałużny, Monika Wiłkość-Dębczyńska, Martyna Gębska-Tołoczko, Karolina Suwała, Robert Kucharski, Aleksander Araszkiewicz
BACKGROUND The aim of this study was to assess and compare peripapillary retinal nerve fiber layer (RNFL) thickness in patients with Alzheimer's disease (AD), primary open-angle glaucoma (POAG), preperimetric glaucoma (PPG), and healthy controls with the use of Spectral Domain Optical Coherence Tomography (SD-OCT). MATERIAL AND METHODS Thirty patients with AD, 30 patients with POAG, 30 patients with PPG, and 30 healthy controls were enrolled in this cross-sectional study. Only 1 randomly selected eye of each patient was analyzed...
February 5, 2019: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/30716199/eye-removal-following-parotid-duct-transposition-surgery-a-survey-of-current-practice-among-veterinary-ophthalmologists
#5
Jennifer L Zimmer, Kathryn A Diehl, Kathern E Myrna
OBJECTIVE: Identify dogs that required removal of an eye that had previously undergone a parotid duct transposition (PDT) and secondly to characterize demographics, surgical technique, and outcomes associated with it. PROCEDURE: An online survey was distributed to American College of Veterinary Ophthalmologists (ACVO) and Veterinary Ophthalmology (VOPH) listservs asking members to report the breed, reason for eye removal, time between surgeries, surgical technique, complications, and additional therapy instituted for dogs requiring removal of an eye subsequent to PDT surgery...
February 4, 2019: Veterinary Ophthalmology
https://read.qxmd.com/read/30710253/glaucoma-care-in-nigeria-is-the-current-practice-poised-to-tackle-this-emerging-sight-threatening-disease
#6
S N Onwubiko, N N Udeh, O Nkwegu, D O Ukwu, N Z Nwachukwu
PURPOSE: To investigate the current practice on glaucoma care with the aim of highlighting its poise to tackle this emerging sight-threatening disease in Nigeria. METHODS: This was a cross-sectional, descriptive, population-based survey involving 88 ophthalmologists. Information on their demographic characteristics, practice profile, challenges and prospects on glaucoma care was collected using a semi-structured, self-administered questionnaire in August 2016. Data were analysed using SPSS 20...
February 1, 2019: International Ophthalmology
https://read.qxmd.com/read/30710112/ophthalmology-specialist-trainee-survey-in-the-united-kingdom
#7
William H Dean, Susannah Grant, Jim McHugh, Oliver Bowes, Fiona Spencer
BACKGROUND: Currently there are a total of 780 post-graduate ophthalmology trainees in the United Kingdom (UK). Post-graduate ophthalmology training in the UK is 7 years in duration, and follows a comprehensive competency-based curriculum. Changes to training have been proposed as part of the government's Shape of Training paper. METHODS: UK ophthalmic trainees and trainers, in partnership with the Royal College of Ophthalmologists, designed a national questionnaire to explore the confidence of trainees in different clinical and non-clinical aspects of ophthalmology...
February 1, 2019: Eye
https://read.qxmd.com/read/30703407/statins-in-ophthalmology
#8
REVIEW
Kenneth G-J Ooi, Pauline Khoo, Veronika Vaclavik, Stephanie L Watson
3-Hydroxy-3-methyl-gutaryl coenzyme A (HMG-CoA) reductase inhibitors or 'statins' are a class of lipid lowering drugs with anti-inflammatory, immunomodulatory, and vascular effects. Statins are increasingly being used in the treatment of a variety of medical conditions. We examine the actions of statins on the eye and its associated ophthalmic disorders. Statins can be synthetic or non-synthetic, and their differentiating derivations may contribute to their varying cholesterol-lowering and pleiotropic effects...
January 28, 2019: Survey of Ophthalmology
https://read.qxmd.com/read/30692707/identifying-and-prioritizing-of-data-elements-for-the-ophthalmology-health-smart-card
#9
Ahmadreza Shamsabadi, Reza Safdari, Marjan Ghazisaeedi, Jebraeil Farzi, Tayebeh Noori, Esmaeil Mehraeen
Background: Recently, with the development of information and communication technology in the healthcare industry, the tools of this technology have different applications such as Health Smart Card in this area. The main application of health smart card in the field of ophthalmology is providing demographic and clinical information for different people. Therefore, this study was done to identify and prioritize the data elements of the ophthalmology health smart card. Methods: This study was a descriptive-development one that was done in 2017...
December 2018: Acta Informatica Medica: AIM
https://read.qxmd.com/read/30683537/-meibomian-glands-dysfunction-and-ocular-surface-in-black-people
#10
A O Eballé, A Ellong, R E Wang, C Y Mbakop, A L Bella, C E Mvogo
Meibomian gland dysfunction is the leading cause of evaporative-type dry eye syndrome. Our goal was to determine the epidemiological and clinical features of meibomian gland dysfunction as well as its impact on the ocular surface in elderly black patients in Cameroon. PATIENTS AND METHODS: We performed a cross-sectional analysis from January 2 through May 31, 2017 in the ophthalmology department of Laquintinie Hospital in Douala, including blacks aged 50 years and older. The examination focused on the Meibomian glands, Tear film Break Up Time and Schirmer I test for qualitative and quantitative assessment of tears...
January 22, 2019: Journal Français D'ophtalmologie
https://read.qxmd.com/read/30676934/low-tension-glaucoma-an-oxymoron-in-ophthalmology
#11
Ciro Costagliola, Luca Agnifili, Leonardo Mastropasqua, Alfonso di Costanzo
No abstract text is available yet for this article.
January 24, 2019: Preventing Chronic Disease
https://read.qxmd.com/read/30676413/postoperative-complications-of-ab-interno-gelatin-microstent
#12
David M Rooney, Husam R Shadid, Les I Siegel, Richard L Watnick, Robert Lesser, Thomas Obertynski, Marc J Siegel, Matthew E Citron, Madeline Hasbrook, Michael J Siegel
PURPOSE: To report 4 previously undescribed postoperative complications in 4 cases of ab-interno XEN45 Gel Stent (XEN) implantation following uncomplicated surgeries. PATIENTS AND METHODS: A total of 51 consecutive XEN implantations performed between July 1, 2017 and April 30, 2018 were reviewed. All cases were performed by 7 experienced glaucoma surgeons affiliated with the William Beaumont Hospital Department of Ophthalmology. Cases with postoperative complications were identified, and a literature review was performed on PubMed...
January 22, 2019: Journal of Glaucoma
https://read.qxmd.com/read/30663070/allergic-contact-dermatitis-probably-due-to-latanoprost-during-treatment-for-alopecia-areata
#13
Maddalena Napolitano, Mariateresa Cantelli, Maria Vastarella, Paola Nappa, Gabriella Fabbrocini, Cataldo Patruno
Latanoprost is a phenyl-substituted analogue of prostaglandin F2α used to treat glaucoma (1). Recently, it has been shown to stimulate eyelash hypertrichosis and therefore it has been proposed as a possible treatment for alopecia (2). Despite the extensive use of the drug in ophthalmology, allergic contact dermatitis (ACD) due to latanoprost has rarely been reported in glaucoma patients (3-6). We report a case of ACD very probably due to latanoprost used for the treatment of alopecia areata in a woman. This article is protected by copyright...
January 21, 2019: Contact Dermatitis
https://read.qxmd.com/read/30662834/two-novel-variants-in-cyp1b1-gene-a-major-contributor-of-autosomal-recessive-primary-congenital-glaucoma-with-allelic-heterogeneity-in-pakistani-patients
#14
Yar Muhammad Waryah, Muhammad Iqbal, Shakeel Ahmed Sheikh, Muhammad Azhar Baig, Ashok Kumar Narsani, Muhammad Atif, Munir Ahmad Bhinder, Attiq Ur Rahman, Azam Iqbal Memon, Muhammad Suleman Pirzado, Ali Muhammad Waryah
AIM: To find the CYP1B1 mutations associated with primary congenital glaucoma (PCG) in Pakistani consanguineous pedigrees. METHODS: After getting informed consent, 11 consanguineous pedigrees belonging to different ethnic groups were enrolled. Detailed medical history was recorded and pedigrees were drawn. The standard ophthalmological examination was done to characterize the phenotype. Genomic DNA was extracted from 10 mL whole blood and coding exons and exon intron boundaries of CYP1B1 gene were directly sequenced...
2019: International Journal of Ophthalmology
https://read.qxmd.com/read/30653210/prevalence-of-foxc1-variants-in-individuals-with-a-suspected-diagnosis-of-primary-congenital-glaucoma
#15
Owen M Siggs, Emmanuelle Souzeau, Francesca Pasutto, Andrew Dubowsky, James E H Smith, Deepa Taranath, John Pater, Julian L Rait, Andrew Narita, Lucia Mauri, Alessandra Del Longo, André Reis, Angela Chappell, Lisa S Kearns, Sandra E Staffieri, James E Elder, Jonathan B Ruddle, Alex W Hewitt, Kathryn P Burdon, David A Mackey, Jamie E Craig
Importance: Both primary and secondary forms of childhood glaucoma have many distinct causative mechanisms, and in many cases a cause is not immediately clear. The broad phenotypic spectrum of secondary glaucoma, particularly in individuals with variants in FOXC1 or PITX2 genes associated with Axenfeld-Rieger syndrome, makes it more difficult to diagnose patients with milder phenotypes. These cases are occasionally classified and managed as primary congenital glaucoma. Objective: To investigate the prevalence of FOXC1 variants in participants with a suspected diagnosis of primary congenital glaucoma...
January 17, 2019: JAMA Ophthalmology
https://read.qxmd.com/read/30623968/trehalose-in-ophthalmology
#16
REVIEW
Cestmir Cejka, Sarka Kubinova, Jitka Cejkova
Trehalose, a disaccharide of glucose, is a naturally occurring nontoxic and nonreducing bioactive sugar. Trehalose is synthetized by many organisms when cells are exposed to stressful conditions, including dehydration, heat, oxidation, hypoxia or even anoxia. Although trehalose is not synthesized by mammalian cells, it has recently been demonstrated to have a number of important properties that indicate its utility in humans. Trehalose enables wound healing by protecting cells, especially cell membranes, from oxidative injury and dessication...
January 9, 2019: Histology and Histopathology
https://read.qxmd.com/read/30621268/transscleral-fixation-of-black-diaphragm-intraocular-lens-in-complete-aniridia-and-aphakia-due-to-posttraumatic-eye-rupture-a-pilot-study
#17
Chorągiewicz Tomasz, Nowomiejska Katarzyna, Haszcz Dariusz, Nowakowska Dominika, Avitabile Teresio, Reibaldi Michele, Anselm Gerhard Maria Jünemann, Toro Mario Damiano, Rejdak Robert
INTRODUCTION: To assess long-term outcomes of implantation of black diaphragm intraocular lens (BD IOL) in post-traumatic aniridia and aphakia due to eye rupture. METHODS: This is a retrospective consecutive case series of 14 eyes with post-traumatic complete aniridia and aphakia treated with scleral fixation BD IOL. Measurements included ophthalmological comorbidities, best corrected visual acuity (BCVA), complications, and postoperative interventions. The average postoperative follow-up period was 36 months...
January 5, 2019: Journal of Clinical Medicine
https://read.qxmd.com/read/30619969/iris-melanoma-relapsing-sixteen-years-after-proton-beam-therapy-the-importance-of-lifelong-follow-up
#18
Laetitia-Claire Msika, Laurence Desjardins, Vincent Cockenpot, Rémi Dendale, Olivier Berges, Khadija Aït Raïs, Gaëlle Pierron, Raymond L Barnhill, Nathalie Cassoux, Alexandre Matet
Purpose: To report a case of locally recurrent spindle-cell iris amelanotic melanoma 16 years after proton-beam therapy. Observations: In 2001, a 45-year-old man presented with an amelanotic iris melanoma, extending from the 5 to 10 o'clock positions on his left eye. High-frequency ultrasonography showed extension of melanoma into the ciliary body. He was initially managed with proton-beam therapy (60 Gy delivered in four fractions over four consecutive days) and underwent ocular and systemic examination at regular intervals over the following years...
March 2019: American Journal of Ophthalmology Case Reports
https://read.qxmd.com/read/30605033/changes-in-pupil-size-and-intraocular-pressure-after-topical-application-of-0-5-tropicamide-to-the-eyes-of-dogs-sedated-with-butorphanol
#19
Sophie Jugant, Aure-Eline Grillot, Faouzi Lyarzhri, Alain Régnier, Jean-Yves Douet
OBJECTIVE: To assess changes in pupil size and intraocular pressure (IOP) following topical application of a 0.5% tropicamide solution in the eyes of healthy butorphanol-sedated dogs. ANIMALS: 12 healthy adult Beagles. PROCEDURES: In a randomized crossover study consisting of 2 treatment periods with a 1-week washout between periods, dogs received an IM injection of butorphanol (0.2 mg/kg) or an equal volume of sterile saline (0.9% NaCl) solution...
January 2019: American Journal of Veterinary Research
https://read.qxmd.com/read/30600544/accuracy-of-detection-of-patients-with-narrow-angles-by-community-optometrists-in-scotland
#20
Roxanne Annoh, Cheng Yi Loo, Brian Hogan, Huai Ling Tan, Ling Shan Tang, Andrew J Tatham
AIM: To examine the accuracy of referrals by community optometrists for suspected primary angle closure, including primary angle closure suspects, primary angle closure and primary angle closure glaucoma. METHODS: A retrospective review of 769 consecutive patients referred by community optometrists to the glaucoma clinic at a university hospital in Scotland. Ninety-five of 715 eligible subjects (13%) were referred due to suspected angle closure. All subjects had a comprehensive eye examination in the glaucoma clinic, including gonioscopy, with angle closure defined according to the International Society of Geographical and Epidemiological Ophthalmology classification as iridotrabecular contact over at least 270 degrees...
January 1, 2019: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
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