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Depression esrd

Delphine S Tuot, Feng Lin, Keith Norris, Jennifer Gassman, Miroslaw Smogorzewski, Elaine Ku
Introduction: Depression is common but underrecognized in patients with chronic kidney disease (CKD), especially among racial/ethnic minorities. We examined the association between depressive symptoms and all-cause mortality (including deaths before and after end-stage renal disease [ESRD]) and whether antidepressant use impacts this association, overall, and by race/ethnicity. Methods: We ascertained whether the presence of depressive symptoms, defined by a Beck Depression Inventory II (BDI) score of >14 at cohort enrollment, was associated with all-cause mortality (before or after ESRD) among study participants of the Chronic Renal Insufficient Cohort (CRIC) overall and by race/ethnicity...
February 2019: KI Reports
Yen-Ling Chiu, Hsiu-Hui Tsai, Yen-Jun Lai, Hsin-Yi Tseng, Yen-Wen Wu, Yu-Sen Peng, Cheng-Ming Chiu, Yi-Fang Chuang
BACKGROUND: Chronic kidney disease exhibits a prominent premature aging phenotype in many different organ systems, including the brain. Nevertheless, a comprehensive characterization of brain aging in non-demented patients with end-stage renal disease (ESRD) is lacking and it remains unclear if the collective changes of cognitive functions and brain structures in ESRD is compatible with aging. METHODS: We compared 56 non-demented, independently living dialysis patients (mean age 59...
February 7, 2019: Journal of the Formosan Medical Association, Taiwan Yi Zhi
Sheena A Gagnier, Barbara A Pieper
End-stage renal disease (ESRD) often is treated with hemodialysis, which carries significant psychological impact along with risks for wound development. Depression is a constant concern. PURPOSE: An integrative review was conducted to examine studies regarding depression in adults receiving hemodialysis for ESRD. METHODS: PubMed and the Cumulative Index for Nursing and Allied Health Literature were searched for English-language publications from 2012 to 2017 regarding ESRD using the search terms epidemiology, hemodialysis, and depression and hemodialysis, depression, nocturnal, and wounds, respectively...
January 2019: Wound management & prevention
David Collister, Jennifer C Rodrigues, Andrea Mazzetti, Kelsi Salisbury, Laura Morosin, Christian Rabbat, K Scott Brimble, Michael Walsh
Background: Depression and anxiety are common and underrecognized in end-stage renal disease (ESRD), are associated with poor outcomes and reduced health-related quality of life, and are potentially treatable. Simple, accurate screening tools are needed. Objective: We examined the operating characteristics of single questions for anxiety and depression from the Edmonton Symptom Assessment System (ESAS) in hemodialysis. Design: Cross-sectional study...
2019: Canadian Journal of Kidney Health and Disease
Sarah H Drangsholt, Ulrik W Cappelen, Nanna von der Lippe, Aud Høieggen, Ingrid Os, Fredrik B Brekke
INTRODUCTION: Patients with end-stage renal disease are burdened by a complex medication regimen, but little is known about the belief about medicine among dialysis- and renal transplant (RTX) patients. Patients' beliefs about medicines may influence drug adherence and thereby affect morbidity and mortality. The aim of the present study was to assess the beliefs about medicine in dialysis as well as after RTX. METHODS: In a prospective study, 301 dialysis patients were followed for up to 5...
February 4, 2019: Hemodialysis International
Kamilla Bargiel-Matusiewicz, Agnieszka Łyś, Paulina Stelmachowska
Medical progress in dialysis therapy made it possible to treat patients with the end-stage renal disease for many years. But at the other side it may lead to profound changes in everyday life and may induce depression and anxiety. The research presented in this article explores the influence of psychological interventions on anxiety and depression levels in patients undergoing dialysis therapy. The experimental design included two experimental groups: cognitive intervention and cognitive/narrative intervention and one control group (standard treatment)...
January 25, 2019: International Journal of Artificial Organs
Feray Gencer, Hilal Yıldıran, Yasemin Erten
OBJECTIVE: Hemodialysis patients may be at risk for malnutrition due to catabolic effects caused by dialysis, loss of amino acids, inadequate nutrient intake, acidosis, and inflammation. Malnutrition may have negative effects on quality of life, mortality, and disease prognosis. This study was conducted to determine the relationship between anthropometric parameters, depression, and quality of life with Malnutrition Inflammation Score (MIS) on 55 patients aged between 18 and 65 years (36 males and 19 females) who have dialysis treatment for 3 days per week for at least 3 months due to end-stage renal disease...
December 27, 2018: Journal of the American College of Nutrition
Y Wang, T Bu, P Yan, H Yao
AIM: To investigate depressive symptoms in recipients of renal transplantation (RTx) compared with patients undergoing hemodialysis (HD) in China. METHODS: Forty-two Chinese recipients of transplant and 42 Chinese patients on hemodialysis were randomly selected from 2011 to 2012. These 2 groups were assessed with the validated Chinese versions of Hospital Anxiety Depression Scales and Structured Clinical Interview for the Diagnostic and Statistical Manual, fourth edition-after matching by sex, age, marital status, educational background, and somatic comorbidities-for investigation of the relationships of depressive symptoms with sex and family income...
December 2018: Transplantation Proceedings
Debela Gela, Daniel Mengistu
Introduction: Patients with end-stage renal disease (ESRD) face multifaceted problems arising from complications of the disease and dialysis that require consistent and, effective self-management from the patients' side, on top of the management offered by health care professionals. However, little is known about the level of self-management and influencing factors among patients with ESRD undergoing hemodialysis in the study area. Therefore, the aim of this study was to assess self-management and associated factors of patients with ESRD undergoing hemodialysis at health facilities in Addis Ababa, Ethiopia...
2018: International Journal of Nephrology and Renovascular Disease
Simge Bardak, Serap Demir, Eda Aslan, Kenan Turgutalp, Havva Didem Celikcan, Murside Esra Dolarslan, Cennet Kılıcarslan, Filiz Karasu, Ayse Jini Gunes, Cemal Kurt, Ahmet Kıykım
PURPOSE: Living with end-stage renal disease may be burdensome, not only for patients, but also for caregivers. In this study, we aim to compare caregiver burden, psychological symptoms in caregivers of peritoneal dialysis (PD), hemodialysis (HD), and transplantation (TX), and find out associated factors. METHODS: A total of 43 PD, 42 HD, 42 TX patients and a total of 127 caregivers that were actively involved with the care of their patients' dialysis were enrolled...
December 4, 2018: International Urology and Nephrology
Xiaojiang Zhan, Caixia Yan, Yanbing Chen, Xin Wei, Jun Xiao, Lijuan Deng, Yuting Yang, Panlin Qiu, Qinkai Chen
Diabetic nephropathy (DN) contributes to end-stage renal disease and kidney dysfunction with a proverbial feature of podocyte injury. Inflammation and insulin resistance is recently implicated in the pathogenesis of diabetic kidney injury. Celastrol exerts critical roles in inflammatory diseases and injury progression. However, its function and mechanism in DN remains elusive. Here, celastrol dose-dependently restored podocyte viability under high glucose (HG) conditions, but with little cytotoxicity in podocyte...
December 2018: Molecular Immunology
Salam El-Majzoub, Istvan Mucsi, Madeline Li, Ghizlane Moussaoui, Mark L Lipman, Karl J Looper, Marta Novak, Soham Rej
BACKGROUND: End-stage renal disease is associated with significant morbidity, high-symptom burden, and health care use. Studies have not yet assessed psychosocial distress and health care utilization in this population. OBJECTIVE: This study examines psychosocial distress and its association with hospitalization and emergency room (ER) visits in patients on maintenance hemodialysis (HD). METHODS: The Distress Assessment and Response Tool (DART) was administered to 80 adults on HD in a single treatment center...
October 10, 2018: Psychosomatics
Sohail Abdul Salim, Lajos Zsom, Wisit Cheungpasitporn, Tibor Fülöp
The prevalence of end-stage renal disease continues to increase in the United States with commensurate need for renal replacement therapies. Hemodialysis continues to be the predominant modality, though less than 2% of these patients will receive hemodialysis in their own home. While home modalities utilizing peritoneal dialysis have been growing, home hemodialysis (HHD) remains underutilized despite studies showing regression in left ventricular mass, improved quality of life, reduced depressive symptoms, and decreased postdialysis recovery time...
January 2019: Seminars in Dialysis
William Crosland, Himanshu Aggarwal, Ayman Farag, Shikha Mehta, Roslyn B Mannon, Jaekyeong Heo, Ami E Iskandrian, Fadi G Hage
BACKGROUND: Depressed left ventricular ejection fraction (LVEF), LV mechanical dyssynchrony (LVMD), and prolonged QTc interval predict poor outcomes in end-stage renal disease (ESRD). Renal transplantation improves mortality in ESRD patients but the effects of transplantation on these indices remain undefined. METHODS: We identified patients with myocardial perfusion imaging (MPI) before and after renal transplantation. A control group consisted of ESRD patients who underwent 2 MPIs but did not receive a transplant...
October 22, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
Tiffany R Washington, Debra J Hain, Sheryl Zimmerman, Iris Carlton-LaNey
Controlled fluid intake is an important aspect of living with end stage renal disease (ESRD), and is complicated by depression, the most common mental health issue affecting individuals with ESRD. Factors that mitigate the deleterious effects of depression are underexplored. This study sought to identify potential mediators between depression and fluid adherence in 107 individuals with ESRD aged 50 years and older by comparing four logistic regression models. Age was associated with an increase in fluid adherence (adjusted odds ratio [AOR]=1...
May 2018: Nephrology Nursing Journal: Journal of the American Nephrology Nurses' Association
Gabriela Cobo, Bengt Lindholm, Peter Stenvinkel
Under normal conditions, inflammation is a protective and physiological response to various harmful stimuli. However, in several chronic debilitating disorders, such as chronic kidney disease, inflammation becomes maladaptive, uncontrolled and persistent. Systemic persistent inflammation has, for almost 20 years, been recognized as a major contributor to the uraemic phenotype (such as cardiovascular disease, protein energy wasting, depression, osteoporosis and frailty), and a predictor of cardiovascular and total mortality...
October 1, 2018: Nephrology, Dialysis, Transplantation
Victoria Semaan, Samar Noureddine, Laila Farhood
BACKGROUND: Dialysis is a lifelong treatment required by end stage renal disease patients who are not able to undergo renal transplantation. Dialysis impacts the patients' quality of life drastically, increasing the risk of mortality. Depression and anxiety are commonly reported among dialysis patients, but their prevalence and correlates vary by sociocultural context. OBJECTIVE: The aim of this study is to examine the prevalence of anxiety and depression and associated factors among patients receiving hemodialysis at a major tertiary referral medical center in Lebanon that receives patients from all over the country...
October 2018: Applied Nursing Research: ANR
Konstadina Griva, Kevin F Y Lam, Mooppil Nandakumar, Jo-An H Ng, Hayley McBain, Stanton P Newman
OBJECTIVE: Depression is often comorbid with End-Stage Renal Disease, and associated with poor adherence and clinical outcomes but course of symptoms is variable. This study sought to describe the long-term trajectories of anxiety and depression in hemodialysis patients, to identify predictors of these trajectories over 12 months and to evaluate the effectiveness of the HEmoDialysis Self-Management Randomized Trial (HED SMART) against usual care on symptoms of anxiety and depression...
October 2018: Journal of Psychosomatic Research
Ł Czyżewski, P Frelik, J Wyzgał, Ł Szarpak
INTRODUCTION: End-stage renal disease (ESRD) has a significant impact on a patient's quality of life (QoL). The optimal treatment for ESRD is kidney transplantation (KTx), which aims to extend and improve QoL. The aim of the study was to assess a QoL in KTx recipients. METHODS: Our study included 118 post-KTx patients. The research tool employed for assessment was a questionnaire consisting of standardized instruments: the 36-item Short Form (SF-36); the Kidney Disease Quality of Life (KDQOL) instrument; and the Depression, Anxiety, and Stress (DASS) scale...
July 2018: Transplantation Proceedings
Maryam Moosavi Nejad, Nahid Shahgholian, Rahele Samouei
INTRODUCTION: Patients undergoing hemodialysis have a low level of health and mindfulness technique in mind-body medicine is used to help patients with chronic illness. Therefore, this clinical trial was conducted to determine the effect of the mindfulness program on the general health of patients undergoing treatment with hemodialysis. METHODS: Sixty hemodialysis patients were selected through the convenient method and randomly divided into experimental and control groups...
2018: Journal of Education and Health Promotion
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