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JOURNAL ARTICLE
Wei Cheng, Yun Xu, Haibo Jiang, Jun Li, Zhigang Hou, Haibin Meng, Wei Wang, Chengliang Chai, Jianmin Jiang
BACKGROUND: Limited studies have explored the impact of the Omicron variant on SARS-CoV-2 infection, hospitalization, and associated factors among people living with HIV, particularly in China. The adjustment of preventive policies since December 2022 in China presents an opportunity to evaluate the real-world factors influencing SARS-CoV-2 infection and related hospitalization among people living with HIV. OBJECTIVE: This study aimed to investigate SARS-CoV-2 infection, hospitalization rates, and associated factors among people living with HIV following the adjustment of preventive policies from December 2022 to February 2023 in southeastern China...
April 17, 2024: JMIR Public Health and Surveillance
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JOURNAL ARTICLE
Yi Li, Jing Li, Bin Wang, Quanmin Jing, Yujie Zeng, Aijie Hou, Zhifang Wang, Aijun Liu, Jinliang Zhang, Yaojun Zhang, Ping Zhang, Daming Jiang, Bin Liu, Jiamao Fan, Jun Zhang, Li Li, Guohai Su, Ming Yang, Weihong Jiang, Peng Qu, Hesong Zeng, Lu Li, Miaohan Qiu, Leisheng Ru, Shaoliang Chen, Yujie Zhou, Shubin Qiao, Gregg W Stone, Dominick J Angiolillo, Yaling Han
IMPORTANCE: Purinergic receptor P2Y12 (P2Y12) inhibitor monotherapy after a certain period of dual antiplatelet therapy (DAPT) may be an attractive option of maintenance antiplatelet treatment for patients undergoing percutaneous coronary intervention (PCI) who are at both high bleeding and ischemic risk (birisk). OBJECTIVE: To determine if extended P2Y12 inhibitor monotherapy with clopidogrel is superior to ongoing DAPT with aspirin and clopidogrel after 9 to 12 months of DAPT after PCI in birisk patients with acute coronary syndromes (ACS)...
April 17, 2024: JAMA Cardiology
#3
JOURNAL ARTICLE
Liu-Yun Dai, Lei Hou, Hua Wang, Li-Song Fu, Yan-Xia Wang, Xiao-Lin Li, Wan-Bin Wang, Qi-Bin Liang
Microplastic pollution in the soil environment has received extensive attention, but the effects of different land use patterns on the sub-watershed scale on soil microplastic pollution are poorly understood. The Luoshijiang sub-watershed in the north of Erhai Lake was selected as the research object, and the characteristics of microplastic pollution in farmland, riparian zone, grassland, and woodland soils were analyzed. The pollution risks of microplastics in the four types of soil were assessed using the polymer risk index method, and the effects of land use patterns on the distribution and risk of microplastic pollution were further explored...
May 8, 2024: Huan Jing Ke Xue= Huanjing Kexue
#4
JOURNAL ARTICLE
Jiangshan Xu, Pengcheng Guo, Shijie Hao, Shuncheng Shangguan, Quan Shi, Giacomo Volpe, Keke Huang, Jing Zuo, Juan An, Yue Yuan, Mengnan Cheng, Qiuting Deng, Xiao Zhang, Guangyao Lai, Haitao Nan, Baihua Wu, Xinyi Shentu, Liang Wu, Xiaoyu Wei, Yujia Jiang, Xin Huang, Fengyu Pan, Yumo Song, Ronghai Li, Zhifeng Wang, Chuanyu Liu, Shiping Liu, Yuxiang Li, Tao Yang, Zhicheng Xu, Wensi Du, Ling Li, Tanveer Ahmed, Kai You, Zhen Dai, Li Li, Baoming Qin, Yinxiong Li, Liangxue Lai, Dajiang Qin, Junling Chen, Rong Fan, Yongyin Li, Jinlin Hou, Michael Ott, Amar Deep Sharma, Tobias Cantz, Axel Schambach, Karsten Kristiansen, Andrew P Hutchins, Berthold Göttgens, Patrick H Maxwell, Lijian Hui, Xun Xu, Longqi Liu, Ao Chen, Yiwei Lai, Miguel A Esteban
The mechanism by which mammalian liver cell responses are coordinated during tissue homeostasis and perturbation is poorly understood, representing a major obstacle in our understanding of many diseases. This knowledge gap is caused by the difficulty involved with studying multiple cell types in different states and locations, particularly when these are transient. We have combined Stereo-seq (spatiotemporal enhanced resolution omics-sequencing) with single-cell transcriptomic profiling of 473,290 cells to generate a high-definition spatiotemporal atlas of mouse liver homeostasis and regeneration at the whole-lobe scale...
April 16, 2024: Nature Genetics
#5
JOURNAL ARTICLE
Yinjing Hou, Bo Liu
Hypertension can cause hearing loss, but there is no clear definition of the mechanism(s) involved. The study aimed to explore the role of vascular endothelial dysfunction in hypertension with hearing loss. Patients with hypertension were divided into two groups based on hearing loss. Pure tone audiometry (PTA) and endothelial function testing were performed. A total of 216 (432 ears) hypertensive patients were divided into hypertension with hearing loss group (n = 104) and hypertension without hearing loss group (n = 112)...
April 16, 2024: Angiology
#6
JOURNAL ARTICLE
Jiatai Gong, Qianjin Zhang, Ruizhi Hu, Xizi Yang, Chengkun Fang, Liping Yao, Jing Lv, Long Wang, Mingkun Shi, Wentao Zhang, Siqi Ma, Hongkun Xiang, Hongfu Zhang, De-Xing Hou, Yulong Yin, Jianhua He, Lijun Peng, Shusong Wu
Obesity is becoming a major global health problem in children that can cause diseases such as type 2 diabetes and metabolic disorders, which are closely related to the gut microbiota. However, the underlying mechanism remains unclear. In this study, a significant positive correlation was observed between Prevotella copri (P. copri) and obesity in children ( p = 0.003). Next, the effect of P. copri on obesity was explored by using fecal microbiota transplantation (FMT) experiment. Transplantation of P...
2024: Gut Microbes
#7
JOURNAL ARTICLE
Lu Chen, Shan Ye, Davan Murphy, Jieying Wu, Hui Zhang, Hong Liu, Boliang Zou, Guanghao Hou, Nan Zhang, Tielun Yin, Richard A Smith, Dongsheng Fan
INTRODUCTION: Pseudobulbar palsy is a common symptom in patients with amyotrophic lateral sclerosis (ALS), but it is often underdiagnosed or misdiagnosed as other diseases. The Center for Neurologic Study Lability Scale (CNS-LS) is a self-report scale consisting of seven questions designed for evaluating pseudobulbar affect (PBA). The current study aimed to validate a Chinese version of the CNS-LS. METHODS: The Chinese version of the CNS-LS was obtained through a standardized forward-backward translation and cultural adaptation...
April 16, 2024: Neurology and Therapy
#8
JOURNAL ARTICLE
P Wang, X W Qian, W J Jiang, H S Wang, J Hou, J Q Sun, X C Wang, X W Zhai
Objective: To evaluate the efficacy of allogeneic hematopoietic stem cell transplantation for the treatment of combined immunodeficiency (CID) and explore prognostic risk factors. Methods: In this retrospective cohort study, clinical characteristics, laboratory tests and prognosis of 73 CID children who underwent allogeneic hematopoietic stem cell transplantation from February 2014 to April 2022 in the Children's Hospital of Fudan University were analyzed. Based on the subtypes of diseases, all patients were divided into severe combined immunodeficiency disease (SCID) group and other CID group...
April 16, 2024: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
#9
JOURNAL ARTICLE
Takaaki Inoue, Hirokazu Tanaka, Tomoko Masuda, Akinori Iba, Mitsuhiro Tambo, Shinsuke Okada, Terunobu Hou, Ryoji Takazawa, Hirofumi Izaki, Shuzo Hamamoto, Masato Fujisawa
OBJECTIVES: This study aimed to investigate perioperative complications and the details of postoperative ureteral stricture after ureteroscopy with laser lithotripsy (URS-L) for upper urinary tract stones in Japan. METHODS: Patient data on intra- and postoperative complications after ureteroscopy using URS-L were retrospectively collected from multiple centers in Japan between April 2017 and March 2020 with the cooperation of the Japanese Society of Endourology and Robotics...
April 15, 2024: International Journal of Urology: Official Journal of the Japanese Urological Association
#10
JOURNAL ARTICLE
Xin Lv, Jing-Jing Lu, Si-Meng Song, Yi-Ru Hou, Yan-Jun Hu, Yan Yan, Tao Yu, Dong-Man Ye
INTRODUCTION: To evaluate the diagnostic efficiency among the clinical model, the radiomics model and the nomogram that combined radiomics features, frozen section (FS) analysis and clinical characteristics for the prediction of lymph node (LN) metastasis in patients with papillary thyroid cancer (PTC). METHODS: A total of 208 patients were randomly divided into two groups randomly with a proportion of 7:3 for the training groups (n = 146) and the validation groups (n = 62)...
April 15, 2024: Clinical Otolaryngology
#11
JOURNAL ARTICLE
Qianting Zhou, Jiayan Li, Lipei Luo, Shuling Min, Li Wang, Lixiu Peng, Yinglan Hou, Ping He, Song He, Shixing Tang, Hongliang Chen
BACKGROUND: Genital infection with Chlamydia trachomatis (C. trachomatis) is a major public health issue worldwide. It can lead to cervicitis, urethritis, and infertility. This study was conducted to determine the characteristics of genital C. trachomatis infection among women attending to the infertility and gynecology clinics. METHODS: Endocervical swabs were collected from 8,221 women for C. trachomatis nucleotide screening and genotyping, while serum samples were collected for C...
April 15, 2024: BMC Infectious Diseases
#12
JOURNAL ARTICLE
Hongze Wang, Guiqiong Liu, Aimin Zhou, Huiguo Yang, Kun Kang, Sohail Ahmed, Biao Li, Umar Farooq, Fuqing Hou, Chaoli Wang, Xue Bai, Yan Chen, Yi Ding, Xunping Jiang
This research aimed to investigate effects of different yeast culture (YC) levels on in vitro fermentation characteristics and bacterial and fungal community under high concentrate diet. A total of 5 groups were included in the experiment: control group without YC (CON), YC1 (0.5% YC proportion of substrate dry matter), YC2 (1%), YC3 (1.5%) and YC4 (2%). After 48 h of fermentation, the incubation fluids and residues were collected to analyze the ruminal fermentation parameters and bacterial and fungal community...
April 15, 2024: AMB Express
#13
JOURNAL ARTICLE
W Zhang, L X Tang, P P Wang, X X Chen, X J Yang, X Xiao, Y Han, W T Ge
Objective: To explore the clinical characteristics, pathological features, and diagnosis and treatment strategies of nasal chondromesenchymal hamartoma (NCMH) in infants and young children. Methods: A retrospective analysis was conducted on seven cases of NCMH infants and young children admitted to Beijing Children's Hospital, Capital Medical University from April 2015 to January 2022. The cohort included 5 males and 2 females, aged from 6 days to 2 years and 3 months. General information, clinical symptoms, imaging findings, treatment plans, postoperative complications, recurrence and follow-up time were collected, summarized and analyzed...
April 7, 2024: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
#14
RANDOMIZED CONTROLLED TRIAL
Xinyue Hou, Jianquan Wang, Zefeng Kang, Yingxin Yang, Xiaoping Yao, Fengmei Zhang, Jing Yao, Jingsheng Yu, Xinquan Liu, Fengming Liang, Xiaoyi Yu, Man Song
OBJECTIVES: To observe the clinical effect and safety of auricular point sticking combined with periocular needle-embedding therapy for pseudomyopia and prevention of true myopia. METHODS: A total of 269 children with pseudomyopia were randomized into an observation group (134 cases, 2 cases dropped out) and a control group (135 cases, 5 cases dropped out). In the control group, the healthy education was provided. In the observation group, besides the intervention as the control group, the auricular point sticking was delivered at gan (CO12 ), pi (CO13 ), xin (CO15 ) and yan (LO5 ) on one ear in each treatment, combined with periocular needle-embedding technique at bilateral Cuanzhu (BL 2), Yuyao (EX-HN 4) and Sibai (ST 2)...
April 12, 2024: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
#15
JOURNAL ARTICLE
Yuanyuan Xiong, Jingxian Li, Xiaoxuan Wang, Xinyue Chi, Shuyuan Li, Yanfei Sun, Zheng Tang, Zishan Hou, Jiangzhou Xie, Zhiyu Yang, Yi-Ming Yan
In the quest for proficient electrocatalysts for ammonia's electrocatalytic nitrogen reduction, cobalt oxides, endowed with a rich d-electron reservoir, have emerged as frontrunners. Despite the previously evidenced prowess of CoO in this realm, its ammonia yield witnesses a pronounced decline as the reaction unfolds, a phenomenon linked to the electron attrition from its Co2+ active sites during electrocatalytic nitrogen reduction reaction (ENRR). To counteract this vulnerability, we harnessed electron-laden phosphorus (P) elements as dopants, aiming to recalibrate the electronic equilibrium of the pivotal Co active site, thereby bolstering both its catalytic performance and stability...
April 15, 2024: Inorganic Chemistry
#16
JOURNAL ARTICLE
Jia-Xun Li, Ling-Rui Meng, Bao-Ke Hou, Xiao-Lu Hao, Da-Jiang Wang, Ling-Hui Qu, Zhao-Hui Li, Lei Zhang, Xin Jin
OBJECTIVE: Autosomal recessive bestrophinopathy (ARB), a retinal degenerative disease, is characterized by central visual loss, yellowish multifocal diffuse subretinal deposits, and a dramatic decrease in the light peak on electrooculogram. The potential pathogenic mechanism involves mutations in the BEST1 gene, which encodes Ca2+ -activated Cl- channels in the retinal pigment epithelium (RPE), resulting in degeneration of RPE and photoreceptor. In this study, the complete clinical characteristics of two Chinese ARB families were summarized...
April 15, 2024: Current Medical Science
#17
JOURNAL ARTICLE
Kexin Dong, Chunyan Wu, Xuerong Hou, Yanhong Zeng, Lu Luo
BACKGROUND: Selection of high-quality blastocysts is the most important factor determining the success of assisted reproductive technology. The objective of this study is to assess the values of blastocyst morphological quality and development speed for predicting euploidy and clinical pregnancy outcome. METHODS: A total of 155 preimplantation genetic testing cycles including 959 blastocysts and 154 euploid blastocyst transfer cycles conducted between January 2018 and December 2019 were retrospectively analysed...
December 2024: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
#18
JOURNAL ARTICLE
Hui Ding, Qin Zhang, Yan-Ping Shu, Bin Tian, Ji Peng, Yong-Zhe Hou, Gang Wu, Li-Yun Lin, Jia-Lin Li
BACKGROUND: Adolescent major depressive disorder (MDD) is a significant mental health concern that often leads to recurrent depression in adulthood. Resting-state functional magnetic resonance imaging (rs-fMRI) offers unique insights into the neural mechanisms underlying this condition. However, despite previous research, the specific vulnerable brain regions affected in adolescent MDD patients have not been fully elucidated. AIM: To identify consistent vulnerable brain regions in adolescent MDD patients using rs-fMRI and activation likelihood estimation (ALE) meta-analysis...
March 19, 2024: World Journal of Psychiatry
#19
JOURNAL ARTICLE
Xiaohui Hou, Meng Wu, Jingjing Chen, Rui Zhang, Yan Wang, Shuwen Zhang, Zaixin Yuan, Jian Feng, Liqin Xu
BACKGROUND: The radiographic classification of pulmonary nodules into benign versus malignant categories is a pivotal component of early lung cancer diagnosis. The present study aimed to investigate clinical and computed tomography (CT) clinical-radiomics nomogram for preoperative differentiation of benign and malignant pulmonary nodules. METHODS: This retrospective study included 342 patients with pulmonary nodules who underwent high-resolution CT (HRCT) examination...
March 29, 2024: Journal of Thoracic Disease
#20
JOURNAL ARTICLE
Rongna Hou, Mengyao Song, Xueliang Zhou, Chengzhi Zhang, Dechao Jiao
BACKGROUND: Biliary stent dysfunction is challenging to treat in clinic. The retrograde track method (RTM) has a promising clinical application in the reopening of dysfunctional biliary stents. This study aimed to evaluate the clinical value of the RTM in reopening dysfunctional biliary stents. METHODS: From February 2013 to January 2020, 151 patients underwent percutaneous transhepatic biliary interventional procedures for reopening dysfunctional biliary stents at the First Affiliated Hospital of Zhengzhou University, and 25 patients (12 females, 13 males; mean age 63...
April 3, 2024: Quantitative Imaging in Medicine and Surgery
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