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https://read.qxmd.com/read/30887955/-socio-demographic-indicators-of-alcohol-dependence-in-patients-treated-for-addiction-in-a-post-industrial-city
#1
Marcin Kozak, Magdalena Piegza, Piotr Ścisło, Karina Badura-Brzoza, Piotr Wacław Gorczyca
BACKGROUND: The aim of the study was to evaluate the influence of the place of living on the prevalence of the alcohol dependence syndrome (ADS) and to find its possible connections with socio-demographic data within a post-industrial city with a population > 100 000 inhabitants. MATERIAL AND METHODS: The study was carried out in 2004-2012 on a group of 431 patients living in Bytom with diagnosed ADS treated either in psychiatric wards or in outpatient psychiatric clinics...
March 7, 2019: Medycyna Pracy
https://read.qxmd.com/read/30886054/the-synaptomic-theory-of-behavior-and-brain-disease
#2
Seth G N Grant
The purpose of this article is to outline a new molecular and synaptic theory of behavior called the "synaptomic theory," named because it is centered on the synaptome-the complement of synapses in the brain. Synaptomic theory posits that synapses are structures of high molecular complexity and vast diversity that are observable in maps of the brain and that these synaptome maps are fundamental to behavior. Synaptome maps are a means of writing or storing information that can be retrieved by the patterns of activity that stimulate synapses...
March 18, 2019: Cold Spring Harbor Symposia on Quantitative Biology
https://read.qxmd.com/read/30873690/psychiatric-outcomes-of-patients-with-severe-agitation-following-administration-of-prehospital-ketamine
#3
Jacob A Lebin, Arvin R Akhavan, Daniel S Hippe, Melissa H Gittinger, Jagoda Pasic, Andrew M McCoy, Marie C Vrablik
BACKGROUND: Ketamine is an emerging drug used in the management of undifferentiated, severe agitation in the prehospital setting. However, prior work has indicated that ketamine may exacerbate psychotic symptoms in patients with schizophrenia. The objective of this study was to describe psychiatric outcomes in patients who receive prehospital ketamine for severe agitation. METHODS: This is a retrospective cohort study, conducted at two tertiary academic medical centers, utilizing chart review of patients requiring prehospital sedation for severe agitation from 01/01/2014 - 06/30/2016...
March 15, 2019: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://read.qxmd.com/read/30869214/-severe-burned-patient-rehabilitation
#4
Claire Nicolas, Olivier Maréchal
Severe burned patient rehabilitation. The rehabilitation of the severe burn requires multidisciplinary care in a specialized rehabilitation center. We present in this article, the care offered in our service, detailing in particular the psychological aspects. Indeed, some patients with severe burns have a psychiatric history, while others will present a status with post-traumatic stress disease following the burn. The general principles of rehabilitation are the establishment of various ways of compression to fight against hypertrophy, as well as the achievement of postures to limit retractions...
December 2018: La Revue du Praticien
https://read.qxmd.com/read/30859946/17-d2-receptor-partial-agonists-in-dual-disorders-use-of-aripiprazole-in-psychotic-disorder-and-comorbid-substance-use-disorder
#5
Daniel Hernandez Huerta, Elena Begoña Alonso Sanchez, Carmen Aldara Carrajo Garcia, Rocio Torralba Viorreta
OBJECTIVE: Dopaminergic mechanisms are involved in addiction but few effective drugs have been developed to treat it. Recent research has highlighted dopamine D2 receptor partial agonists, like aripiprazole, as a potential treatment for different types of substance dependence. In this study we investigate the use of both oral or long-acting injectable (LAI) aripiprazole in the treatment of dual disorders, specifically focusing on patients with psychotic disorder and comorbid substance use disorder...
February 2019: CNS Spectrums
https://read.qxmd.com/read/30858876/favourable-short-term-course-and-outcome-of-pediatric-anxiety-spectrum-disorders-a-prospective-study-from-india
#6
Preeti Kandasamy, Satish C Girimaji, Shekhar P Seshadri, Shoba Srinath, John Vijay Sagar Kommu
Background: Although anxiety disorders are the most prevalent psychiatric disorders among children and adolescents, there is a paucity of research on the course and outcome of anxiety spectrum disorders in low and middle-income countries. Methods: 60 children and adolescents aged 6-16 years with anxiety spectrum disorders attending the child and adolescent psychiatry department in a tertiary care center from India were included after taking written informed consent and assent in this prospective study conducted between April 2012 to May 2014...
2019: Child and Adolescent Psychiatry and Mental Health
https://read.qxmd.com/read/30858636/impact-of-gabapentin-adjunct-use-with-benzodiazepines-for-the-treatment-of-alcohol-withdrawal-in-a-psychiatric-hospital
#7
Nina Vadiei, Tawny L Smith, Amy E Walton, Kimberly L Kjome
Introduction: Benzodiazepines are currently the gold standard for treatment of alcohol withdrawal. Gabapentin has growing evidence to support its use in the treatment of alcohol use disorder, however there is limited evidence regarding its role in the treatment of alcohol withdrawal. The purpose of this study was to determine if adjunctive gabapentin reduces the need for benzodiazepine (BZD) administration during alcohol withdrawal. Methods: This was a retrospective single-center cohort study...
February 15, 2019: Psychopharmacology Bulletin
https://read.qxmd.com/read/30855719/exploratory-study-examining-associations-between-prescription-opioid-dose-and-delay-discounting-in-patients-with-chronic-pain
#8
Benjamin J Morasco, Steven K Dobscha, Stephanie Hyde, Suzanne H Mitchell
OBJECTIVE: Although some research has identified correlates of high-dose opioid prescriptions, relatively little is known about factors that lead to higher doses. Delay discounting (DD), defined as the subjective value of a reward declining as a function of the delay to that reward, is an objective measure of impulsivity. DD is commonly studied in the context of addictive behaviors, and findings consistently demonstrate greater DD among individuals with opioid use disorders. The authors conducted a preliminary investigation to examine the extent to which DD is associated with prescription opioid dose among patients with musculoskeletal pain...
January 2019: Journal of Opioid Management
https://read.qxmd.com/read/30855682/from-their-perspective-the-connection-between-life-stressors-and-health-care-service-use-patterns-of-homeless-frequent-users-of-the-emergency-department
#9
Megan Moore, Kelsey M Conrick, Ashok Reddy, Ann Allen, Craig Jaffe
The perspective of homeless adults on their health care service utilization is not well studied. This article describes a study that used in-depth, semistructured interviews with 18 individuals to highlight the viewpoints of homeless people who are frequent users of the emergency department (ED) about the influence of life events on service utilization. Participants reported high levels of pain and comorbid psychiatric, substance use, and medical conditions. They also reported an identifiable pattern of health care utilization, often centered on a crisis event, influenced by high perceived medical needs, inability to cope after crisis, predisposing vulnerability from social determinants of health, and health care system factors...
March 11, 2019: Health & Social Work
https://read.qxmd.com/read/30852390/well-being-in-patients-with-schizophrenia-mood-and-personality-disorders-attending-psychiatric-services-in-the-community-a-controlled-study
#10
Valentina Stanga, Cesare Turrina, Paolo Valsecchi, Emilio Sacchetti, Antonio Vita
BACKGROUND: Poor attention is paid by recent research to the prevalence of mental well-being in psychiatric patients and the comparison between groups with different diagnoses. Data suggest that the presence of mental illness does not necessarily mean the absence of well-being, particularly in stable outpatients. METHODS: A consecutive series of 375 patients attending two community mental health centers was given the Mental Health Continuum Short Form (MHC-SF) and the Clinical Global Impression - Severity scale...
March 5, 2019: Comprehensive Psychiatry
https://read.qxmd.com/read/30851203/chronic-pruritus-patients-with-psychiatric-and-psychosomatic-comorbidity-are-highly-burdened-a-longitudinal-study
#11
G Schneider, A Grebe, P Bruland, G Heuft, S Ständer
Chronic Pruritus (CP) is a highly impairing symptom, often of multifactorial origin, with a certain percentage of psychosomatic/psychiatric (PP) comorbidity. Up to now it has not been investigated in large samples of CP patients how psychiatric comorbidity may interact with symptom presentation and treatment of CP. This was the objective of our study. We analyzed data from the database of the Center for Chronic Pruritus (CCP) of the University Hospital Münster including sociodemographic and clinical data, interdisciplinary consultation results, International Forum for the Study of Itch (IFSI) classification, pruritus intensity, Dermatologic Life Quality Index (DLQI; only for patients with IFSI groups I and III), and Hospital Anxiety and Depression Scale (HADS)...
March 9, 2019: Journal of the European Academy of Dermatology and Venereology: JEADV
https://read.qxmd.com/read/30850129/cerebellar-gray-matter-volume-is-associated-with-cognitive-function-and-psychopathology-in-adolescence
#12
Torgeir Moberget, Dag Alnæs, Tobias Kaufmann, Nhat Trung Doan, Aldo Córdova-Palomera, Linn Bonaventure Norbom, Jaroslav Rokicki, Dennis van der Meer, Ole A Andreassen, Lars T Westlye
BACKGROUND: Accumulating evidence supports cerebellar involvement in mental disorders, such as schizophrenia, bipolar disorder, depression, anxiety disorders, and attention-deficit/hyperactivity disorder. However, little is known about the cerebellum in developmental stages of these disorders. In particular, whether cerebellar morphology is associated with early expression of specific symptom domains remains unclear. METHODS: We used machine learning to test whether cerebellar morphometric features could robustly predict general cognitive function and psychiatric symptoms in a large and well-characterized developmental community sample centered on adolescence (Philadelphia Neurodevelopmental Cohort, n = 1401, age 8-23 years)...
January 30, 2019: Biological Psychiatry
https://read.qxmd.com/read/30849968/psychometric-properties-of-the-chinese-mainland-version-of-the-palliative-care-spiritual-care-competency-scale-pcsccs-m-in-nursing-a-cross-sectional-study
#13
Yanli Hu, Fan Li, Jeng-Fong Chiou
BACKGROUND: Spiritual care competencies are among the primary professional skills that enable best practices in nursing. Assessing these competencies and identifying those that are insufficient are important tasks. The traditional Chinese version of the Palliative Care Spiritual Care Competency Scale (PCSCCS) used in Taiwan is a well-validated tool to measure palliative caregivers' competencies in providing spiritual care. However, whether this scale is valid and reliable for use with nurses in other health-care contexts is unknown...
March 8, 2019: BMC Palliative Care
https://read.qxmd.com/read/30844875/psychotropics-in-your-medicine-cabinet-a-case-study-of-dimenhydrinate-use
#14
Xia Wen, Francesca Di Paola, Nitin Chopra
: Reporting of intoxication and withdrawal from aberrant use of over-the-counter medication has been sparse and inconsistent in literature. Attributed to their anticholinergic properties, medications such as dimenhydrinate (Gravol) taken in supratherapeutic doses have been associated with euphoria, anxiolysis, and hallucinations. We present a case of a woman in her forties, with a psychiatric history of bipolar disorder, and complex concurrent medical history including familial Mediterranean fever (FMF), and fibromyalgia, admitted for withdrawal management of her intravenous dimenhydrinate use...
March 4, 2019: Journal of Addiction Medicine
https://read.qxmd.com/read/30842919/evaluation-and-optimization-of-take-home-naloxone-in-an-academic-medical-center
#15
Jordan Cooler, Clint A Ross, Sophie Robert, Lauren Linder, Ann Marie Ruhe, Achsah Philip
With the United States in the midst of an opioid overdose epidemic, efforts to reduce overdose deaths have increased. Expanding access to the opioid antagonist naloxone can combat the epidemic. A pilot project in a psychiatric hospital resulted in the development of a screening tool in the electronic medical record (EMR) to help pharmacists identify adult inpatients at high risk of opioid overdose. Pharmacists can facilitate these patients being discharged with take-home naloxone. The purpose of this project was to optimize the screening tool for nonpsychiatric adult inpatient areas...
March 2019: Mental Health Clinician
https://read.qxmd.com/read/30842916/rates-of-new-antipsychotic-prescriptions-and-continuation-at-discharge-from-a-medical-unit-in-a-community-teaching-hospital-serving-rural-counties
#16
Stephanie V Phan, Yelena Lugin, Katie Morgan
Introduction: Antipsychotics are commonly used during hospitalization to manage a variety of acute indications and may be inadvertently continued at discharge. The purpose of this study was to identify the rate at which patients admitted to nonpsychiatric units were continued on newly prescribed antipsychotics at discharge from a rural community teaching hospital. Methods: This study was a retrospective chart review of adult patients admitted to a large community teaching hospital and initiated on an antipsychotic from August 1, 2016, to August 31, 2017...
March 2019: Mental Health Clinician
https://read.qxmd.com/read/30842915/implementation-of-a-qtc-interval-monitoring-protocol-by-pharmacists-to-decrease-cardiac-risk-in-at-risk-patients-in-an-acute-care-inpatient-psychiatric-facility
#17
Nicole M Daniel, Kim Walsh, Henry Leach, Lauren Stummer
Introduction: Many medications commonly prescribed in psychiatric hospitals can cause QTc-interval prolongation, increasing a patient's risk for torsades de pointes and sudden cardiac death. There is little guidance in the literature to determine when an electrocardiogram (ECG) and QTc-interval monitoring should be performed. The primary end point was improvement of the appropriateness of ECGs and QTc-interval monitoring of at-risk psychiatric inpatients at Barnabas Health Behavioral Health Center (BHBH) and Monmouth Medical Center (MMC) following implementation of a standardized monitoring protocol...
March 2019: Mental Health Clinician
https://read.qxmd.com/read/30842914/evaluation-of-dextromethorphan-with-select-antidepressant-therapy-for-the-treatment-of-depression-in-the-acute-care-psychiatric-setting
#18
Jill L Nofziger, Chris Paxos, Jessica Emshoff, Chanda Mullen
Introduction: Dextromethorphan (DXM), an N -methyl-D-aspartate receptor antagonist, may have ketamine-like antidepressant effects. Dextromethorphan is extensively metabolized via cytochrome P450 (CYP) 2D6, and its half-life in extensive metabolizers is 2 to 4 hours. The purpose of this study was to evaluate the effects of DXM in combination with a moderate-to-strong CYP2D6 inhibitor antidepressant on depression in an acute care psychiatric setting. Methods: This was a single-center, retrospective chart review of adult patients with a depressive disorder diagnosis...
March 2019: Mental Health Clinician
https://read.qxmd.com/read/30838927/seizures-nonepileptic-events-trauma-anxiety-or-all-of-the-above
#19
Jay Salpekar
Psychiatric Comorbidity and Traumatic Brain Injury Attribution in Patients With Psychogenic Nonepileptic or Epileptic Seizures: A Multicenter Study of US Veterans Salinsky M, Rutecki P, Parko K, Goy E, Storzbach D, O'Neil M, Binder L, Joos S. Epilepsia. 2018. Epub ahead of print. https://doi.org/10.1111/epi.14542 Objective: To determine the frequency and severity of psychiatric disorders and attribution of seizures to traumatic brain injury (TBI) in veterans with verified psychogenic nonepileptic seizures (PNES) versus epileptic seizures (ES)...
January 2019: Epilepsy Currents
https://read.qxmd.com/read/30838190/precocious-and-early-central-puberty-in-children-with-pre-existing-medical-conditions-a-single-center-study
#20
Sarah Winter, Adélaïde Durand, Raja Brauner
Background: Precocious and early puberty are reported findings in children with pre-existing medical conditions including certain syndromes. Series pertaining to such situations are limited. Methods: A retrospective, single-center study was conducted on children with central precocious puberty (onset before the age of 8 years in girls and 9 years in boys) or early puberty (onset between 8 and 9 years in girls and between 9 and 10.5 years in boys) diagnosed on the background of a known pre-existing chronic significant medical condition...
2019: Frontiers in Pediatrics
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