keyword
https://read.qxmd.com/read/38521610/evaluating-the-carnivorous-efficacy-of-utricularia-aurea-lamiales-lentibulariaceae-on-the-larval-stages-of-anopheles-stephensi-culex-quinquefasciatus-and-aedes-aegypti-diptera-culicidae
#21
JOURNAL ARTICLE
Ajeet Kumar Mohanty, Abhishek Govekar, Charles de Souza, Abhipsa Mohapatra, Malapati Kuppuswamy Janarthanam, Raja Vukanti, Justin J Montemarano, Praveen Balabaskaran Nina
The emergence of insecticide resistance in mosquitoes necessitates the exploration and validation of sustainable biological strategies for controlling mosquitoes in their natural habitats. We assessed the predatory effect of Utricularia aurea Lour (Lamiales: Lentibulariaceae), an aquatic carnivorous plant found in the Indian subcontinent, Japan, and Australia, on 4 instars of Anopheles stephensi Liston, Culex quinquefasciatus Say, and Aedes aegypti Linn (Diptera: Culicidae), in the laboratory and field settings...
March 23, 2024: Journal of Medical Entomology
https://read.qxmd.com/read/38520662/combustion-performance-and-emission-characteristics-of-aloevera-diesel-emulsified-fuel-in-a-di-diesel-engine
#22
JOURNAL ARTICLE
Rajendran Manikandan, Thimmarayan Raja, Kengaiah Vijaya Raja, Gopi Suresh, Rajasekharan Vezhavendhan, Govindasamy Kumaresan, Raju Ganesamoorthy
Nowadays, mankind is very particular about the usage of energy in the most effective manner by keeping the view of less adulterating the atmosphere, which are the key aspects of many scientists all around the world. In this particular study, the aloevera diesel has been chosen as the primary fuel, and studies have been conducted on emission pollutant characteristics by choosing an appropriate diesel engine. Furthermore, stable emulsions have been produced by using aloevera, and the same was mixed with diesel at the ratio of 5% and 10% as the compound...
March 23, 2024: Environmental Science and Pollution Research International
https://read.qxmd.com/read/38520457/novel-35-mm-balloon-expandable-transcatheter-aortic-valve-replacement
#23
JOURNAL ARTICLE
John Jose, Paul V George, Shohiab Ur Riyaz Mirza, Pratheesh George Mathen, Sakthivel Selvaraj, Haynes Raja
No abstract text is available yet for this article.
February 29, 2024: JACC. Cardiovascular Interventions
https://read.qxmd.com/read/38518906/production-optimization-and-characterization-of-partially-purified-anti-mycotic-compound-from-marine-soil-streptomycetes-unexplored-region-of-bay-of-bengal-india
#24
JOURNAL ARTICLE
Ramasamy Vijayakumar, Suresh S S Raja, Chinnasamy Muthukumar, Ponmurugan Karuppiah, Annamalai Panneerselvam, R Jothi Ramalingam, Nooruddin Thajuddin, Ramamoorthy Ayyamperumal
Sixty-eight morphologically distinct isolates of marine actinomycetes were derived from seashore, mangrove, and saltpan ecosystems located between the Palk Strait and Gulf of Mannar region, Bay of Bengal, Tamilnadu. Twenty-five (36.8%) isolates exhibited anti-mycotic activity against Candida albicans and Cryptococcus neoformans in preliminary screening, and 4 isolates with prominent activity were identified and designated at the genus level as Streptomyces sp. VPTS3-I, Streptomyces sp. VPTS3-2, Streptomyces sp...
March 20, 2024: Environmental Research
https://read.qxmd.com/read/38517700/lactic-acid-induced-colloidal-microrheology-of-synovial-fluids
#25
JOURNAL ARTICLE
Nayanjyoti Kakati, Dileep Ahari, Prathu Raja Parmar, Omkar Suresh Deshmukh, Dipankar Bandyopadhyay
The presence of colloidal scaffolds composed of proteins and hyaluronic acid engenders unique viscous and elastic properties to the synovial fluid (SF). While the elastic resistance of SF due to the presence of such nanoscale structures provides the load-bearing capacity, the viscous nature enables fluidity of the joints during the movements to minimize the wear and tear of the adjacent muscle, cartilage, or bone tissues. It is well-known that the hypoxic conditions at the bone joints often increase the lactic acid (LA) concentration due to the occurrence of excess anaerobic respiration during either hyperactivity or arthritic conditions...
March 22, 2024: ACS Biomaterials Science & Engineering
https://read.qxmd.com/read/38517457/automated-category-and-trend-analysis-of-scientific-articles-on-ophthalmology-using-large-language-models-development-and-usability-study
#26
JOURNAL ARTICLE
Hina Raja, Asim Munawar, Nikolaos Mylonas, Mohammad Delsoz, Yeganeh Madadi, Muhammad Elahi, Amr Hassan, Hashem Abu Serhan, Onur Inam, Luis Hernandez, Hao Chen, Sang Tran, Wuqaas Munir, Alaa Abd-Alrazaq, Siamak Yousefi
BACKGROUND: In this paper, we present an automated method for article classification, leveraging the power of large language models (LLMs). OBJECTIVE: The aim of this study is to evaluate the applicability of various LLMs based on textual content of scientific ophthalmology papers. METHODS: We developed a model based on natural language processing techniques, including advanced LLMs, to process and analyze the textual content of scientific papers...
March 22, 2024: JMIR Formative Research
https://read.qxmd.com/read/38517446/macular-pigment-assessment-in-indian-population-using-degree-of-polarization-threshold-impact-of-diet-on-macular-pigment-density
#27
JOURNAL ARTICLE
Payal Sangani, Shelby Temple, Shashank Bhandary, Raja Narayanan, Elizabeth Johnson, Anthony Vipin Das, Md Hasnat Ali, Brijesh Takkar
PURPOSE: To determine macular pigment (MP) density scores in healthy Indians and examine correlations with demographic and lifestyle variables. METHODS: We observed 484 Indians without an ocular pathology. Body mass index (BMI) and self-reported lifestyle factors (sunglasses usage, physical activity, and smoking) were noted. MP density was assessed as the threshold of perception of the shadow of their macular pigments on their retina using a new MP assessment tool (MP-eye)...
March 1, 2024: Translational Vision Science & Technology
https://read.qxmd.com/read/38517006/compensation-in-neonatal-clinical-trials-a-perspective
#28
JOURNAL ARTICLE
Apoorva Mathur, Dilip Raja, Anju Sinha, Subodh S Gupta, Y K Gupta, Anand S Kawade, Ramesh Poluru
Well conducted clinical trials are the mainstay for generating evidence on preferred treatments. In order to adequately protect the interests of the trial participants, the Central Licensing Authority of India has formulated guidelines to determine the quantum of compensation in cases of regulatory clinical trial related injury or death. However, these guidelines do not address the nuances of trials recruiting children aged under 16 years, within which, neonates are the most vulnerable population. Thus, there is a need for addressing this lacuna in the current guidelines...
March 19, 2024: Indian Pediatrics
https://read.qxmd.com/read/38516346/diving-into-cdc-pregnancy-data-in-the-united-states-longitudinal-study-and-interactive-application
#29
JOURNAL ARTICLE
Andrea O Clark-Sevilla, Yun C Lin, Arnav Saxena, Qi Yan, Ronald Wapner, Anita Raja, Itsik Pe'er, Ansaf Salleb-Aouissi
OBJECTIVE: Preterm birth (PTB) is a major determinant of neonatal mortality, morbidity, and childhood disability. In this article, we present a longitudinal analysis of the risk factors associated with PTB and how they have varied over the years: starting from 1968 when the CDC first started, reporting the natality data, up until 2021. Along with this article, we are also releasing an RShiny web application that will allow for easy consumption of this voluminous dataset by the research community...
April 2024: JAMIA Open
https://read.qxmd.com/read/38515346/new-insight-of-chemical-constituents-in-persea-americana-fruit-against-obesity-via-integrated-pharmacology
#30
JOURNAL ARTICLE
Min-Gi Cha, Su-Been Lee, Sang-Jun Yoon, Sang Youn Lee, Haripriya Gupta, Raja Ganesan, Satya Priya Sharma, Sung-Min Won, Jin-Ju Jeong, Dong Joon Kim, Ki-Kwang Oh, Ki-Tae Suk
Persea americana fruit (PAF) is a favorable nutraceutical resource that comprises diverse unsaturated fatty acids (UFAs). UFAs are significant dietary supplementation, as they relieve metabolic disorders, including obesity (OB). In another aspect, this study was focused on the anti-OB efficacy of the non-fatty acids (NFAs) in PAF through network pharmacology (NP). Natural product activity & species source (NPASS), SwissADME, similarity ensemble approach (SEA), Swiss target prediction (STP), DisGeNET, and online Mendelian inheritance in man (OMIM) were utilized to gather significant molecules and its targets...
March 2024: Clinical and Translational Science
https://read.qxmd.com/read/38514400/advancing-entity-recognition-in-biomedicine-via-instruction-tuning-of-large-language-models
#31
JOURNAL ARTICLE
Vipina K Keloth, Yan Hu, Qianqian Xie, Xueqing Peng, Yan Wang, Andrew Zheng, Melih Selek, Kalpana Raja, Chih Hsuan Wei, Qiao Jin, Zhiyong Lu, Qingyu Chen, Hua Xu
MOTIVATION: Large Language Models (LLMs) have the potential to revolutionize the field of Natural Language Processing (NLP), excelling not only in text generation and reasoning tasks but also in their ability for zero/few-shot learning, swiftly adapting to new tasks with minimal fine-tuning. LLMs have also demonstrated great promise in biomedical and healthcare applications. However, when it comes to Named Entity Recognition (NER), particularly within the biomedical domain, LLMs fall short of the effectiveness exhibited by fine-tuned domain-specific models...
March 21, 2024: Bioinformatics
https://read.qxmd.com/read/38514391/light-responsive-dna-nanomaterials-and-their-biomedical-applications
#32
JOURNAL ARTICLE
Raja Muhammad Aqib, Arsalan Umer, Jialin Li, Jianbing Liu, Baoquan Ding
DNA nanomaterials have been widely employed for various biomedical applications. With rapid development of chemical modification of nucleic acid, serials of stimuli-responsive elements are included in the multifunctional DNA nanomaterials. In this review, we summarize the recent advances in light responsive DNA nanomaterials based on photocleavage/photodecage, photoisomerization, and photocrosslinking for efficient bioimaging (including imaging of small molecule, microRNA, and protein) and drug delivery (including delivery of small molecule, nucleic acid, and gene editing system)...
March 21, 2024: Chemistry, An Asian Journal
https://read.qxmd.com/read/38511395/longitudinal-quality-of-life-after-sublobar-resection-and-stereotactic-body-radiation-therapy-for-early-stage-non-small-cell-lung-cancer
#33
JOURNAL ARTICLE
Juan P Wisnivesky, Jeremy Mudd, Kimberly Stone, Christopher G Slatore, Raja Flores, Scott Swanson, William Blackstock, Cardinale B Smith, Mark Chidel, Kenneth Rosenzweig, Claudia Henschke, Jeffrey A Kern
BACKGROUND: Many patients with early-stage lung cancer are not candidates for lobectomy because of various factors, with treatment options including sublobar resection or stereotactic body radiation therapy (SBRT). Limited information exists regarding patient-centered outcomes after these treatments. METHODS: Subjects with stage I-IIA non-small cell lung cancer (NSCLC) at high risk for lobectomy who underwent treatment with sublobar resection or SBRT were recruited from five medical centers...
March 21, 2024: Cancer
https://read.qxmd.com/read/38511256/augmented-mannose-binding-lectin-levels-in-primary-membranous-nephropathy-a-pilot-study
#34
JOURNAL ARTICLE
Deeksha Pal, Neeraj Inamdar, Prabhjot Kaur, Manphool Singhal, Anupam Lal, Ujjwal Gorsi, Ritambhra Nada, Harbir S Kohli, Vinod Kumar, Raja Ramachandran
There is evidence to suggest that M-type phospholipase A2 (PLA2R) antibodies activate the mannose-binding lectin (MBL) cascade, resulting in glomerular damage and proteinuria in patients with primary membranous nephropathy (PMN). Furthermore, there are few reports indicating that aberrant MBL activation is associated with endothelial dysfunction and accelerated atherosclerosis. While PMN is a common cause of adult nephrotic syndrome, and patients are at increased risk of cardiovascular disease (CVD), there is a lack of research that explores the factors that contribute to this condition...
March 21, 2024: Nephrology
https://read.qxmd.com/read/38511040/factors-that-impact-the-outcomes-in-ewing-s-sarcoma-experience-from-a-regional-cancer-center-in-southern-india
#35
JOURNAL ARTICLE
Ankit Batra, Anand Raja, Chandra Kumar Krishnan, Nikita Mehra, Harish Kumar Kaluram, Ramanaiah Kaluvoya, Shirley Sundersingh, Venkatraman Radhakrishnan
UNLABELLED: Ewing's sarcoma family of tumors (EWSFT) is common in the second decade of life. Achieving good outcomes in EWSFT requires a multimodality approach. We report the clinico-pathological features, treatment, and survival outcomes of patients with EWSFT treated at our center. Patients diagnosed and treated for EWSFT at our center from 2009-2017 were included in this study. Data was collected from the patient's case records. Event-free survival (EFS) and overall survival (OS) were estimated using the Kaplan-Meier method...
March 2024: Indian Journal of Surgical Oncology
https://read.qxmd.com/read/38510828/new-grasslands-promote-pollination-but-not-biological-pest-control-in-nearby-arable-fields-in-the-short-term
#36
JOURNAL ARTICLE
Manuela Bürgler, Raja Imran Hussain, Bea Maas, Ronnie Walcher, Dominik Rabl, Bernhard Krautzer, Dietmar Moser, Thomas Frank
UNLABELLED: Agricultural intensification is a major threat to farmland biodiversity and associated ecosystem services. Semi-natural habitats are integral to the preservation of farmland biodiversity and ecosystem services, however, the extent in which they contribute to specific services is largely unclear. We studied predation rates of ground-dwelling predatory arthropods, and pollination success within old permanent grasslands, newly established grasslands and arable fields near and far from new grasslands...
2024: Arthropod-plant Interactions
https://read.qxmd.com/read/38509509/grade-adolopment-of-hyperthyroidism-treatment-guidelines-for-a-pakistani-context
#37
JOURNAL ARTICLE
Russell Seth Martins, Sarah Nadeem, Abeer Aziz, Sajjan Raja, Alina Pervez, Najmul Islam, Asma Ahmed, Aisha Sheikh, Saira Furqan, Nanik Ram, Azra Rizwan, Nashia Ali Rizvi, Mohsin Ali Mustafa, Salima Saleem Aamdani, Bushra Ayub, Muhammad Qamar Masood
INTRODUCTION: The prevalence of hyperthyroidism in Pakistan is 2.9%, which is two times higher than in the United States. Most high-quality hyperthyroidism clinical practice guidelines (CPGs) used internationally originate from high-income countries in the West. Local CPGs in Pakistan are not backed by transparent methodologies. We aimed to produce comprehensive, high-quality CPGs for the management of hyperthyroidism in Pakistan. METHODS: We employed the GRADE-ADOLOPMENT approach utilizing the 2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis as the source CPG...
March 21, 2024: BMC Endocrine Disorders
https://read.qxmd.com/read/38508984/can-locking-plate-fixation-and-free-vascularised-fibular-transfer-with-skin-island-achieve-good-functional-outcome-in-the-treatment-of-large-bone-defects-of-tibia-a-study-of-26-cases
#38
JOURNAL ARTICLE
Jayaramaraju Dheenadhayalan, Asif Imran, Agraharam Devendra, Hari Venkatramani, Purnaganapathi Sundaram Velmurugesan, Shanmuganathan Rajasekaran, Shanmuganathan Raja Sabapathy
BACKGROUND: Despite the availability of multiple treatment options, management of tibial bone loss continues to be a challenge. Free vascularized fibula graft (FVFG) with a skin paddle offers better advantages over the other methods. We aimed to study the functional outcomes and QALY of patients with large tibial bone defects following FVFG with a locking plate in 26 patients. MATERIALS AND METHODS: We analyzed 26 consecutive patients with large tibial bone defects treated by free vascularized fibular graft (FVFG) and stabilization using a long locking plate between 2009 and 2018...
February 28, 2024: Injury
https://read.qxmd.com/read/38508688/investigating-the-impact-of-external-application-of-formalin-and-potassium-permanganate-on-hematological-immunological-and-biochemical-profiles-in-labeo%C3%A2-rohita-fingerlings
#39
JOURNAL ARTICLE
Lukesh Kumar Banjare, Himadri Saha, Arpit Acharya, Md Idrish Raja Khan
The present study aimed to elucidate the suitability of formalin and KMnO4 as therapeutics for fish diseases in Indian major carp, Labeo rohita , while considering their impact on fish stress levels. Acute toxicity tests revealed that the 96-hour LC50 values for formalin and KMnO4 were 66.58 ppm and 2.89 ppm, respectively. Sub-lethal concentrations of formalin (6.65 ppm, 3.32 ppm, and 2.21 ppm) and KMnO4 (0.289 ppm, 0.145 ppm, and 0.096 ppm), along with control groups, were administered to the fish for different exposure periods (24, 48, 72, and 96 hours) and different hematological, biochemical, and immunological parameters were analyzed...
March 20, 2024: Drug and Chemical Toxicology
https://read.qxmd.com/read/38508623/improving-psychosocial-adjustment-to-traumatic-brain-injury-from-acute-to-chronic-injury-through-development-and-evaluation-of-the-mytbi-online-psychoeducation-platform-protocol-for-a-mixed-methods-study
#40
JOURNAL ARTICLE
Lakkhina Troeung, Thilaga L Sarunga Raja, Georgina Mann, Janet Wagland, Colin MacLeod, Angelita Martini
INTRODUCTION: This protocol describes the myTBI study which aims to: (1) develop an online psychoeducation platform for people with traumatic brain injury (TBI), their family members/caregivers, and healthcare staff to improve psychosocial adjustment to TBI across different phases of injury (acute, postacute, and chronic), and (2) undertake an evaluation of efficacy, acceptability, and feasibility. METHODS AND ANALYSIS: A three-stage mixed-methods research design will be used...
March 19, 2024: BMJ Open
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