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Pancreas radiology

A Bauschke
CLINICAL/METHODICAL ISSUE: Exact diagnostic procedures are prerequisite for surgical treatment of bile duct diseases. STANDARD RADIOLOGICAL METHODS: Magnetic resonance cholangiopancreatography may be supplemented by computed tomography (CT) for planning surgical interventions, for staging diagnostics in malignancies and for imaging the vascular anatomy in the upper abdomen. METHODICAL INNOVATIONS: Statements from magnetic resonance cholangiopancreatography (MRCP) and CT may be supplemented via digital workup in selected cases of transplantation medicine and in liver surgery...
February 28, 2019: Der Radiologe
K Vinod Kumar, V N Unni, N Kachare, N John, P K Bipi, J Pullockara
Hypercalcemia rarely causes acute pancreatitis due to secretory block in the pancreas and damage by accumulated proteases. Hypercalcemia, though described in granulomatous disorders, is uncommon in tuberculosis. Acute kidney injury is known to occur with acute pancreatitis, secondary to sepsis and septic shock; however, acute pancreatitis resulting in acute cortical necrosis is very rare. We report a 22-year-old woman, who presented with pain abdomen and vomiting. She was found to have features of acute pancreatitis, both biochemically and radiologically...
January 2019: Indian Journal of Nephrology
Gracijela Bozovic, Rille Pullerits, Arne Ståhl, Kristina Ydström, Daniel Wenger, Jan Marsal, Pontus Thulin, Kristofer Andréasson
BACKGROUND: Systemic sclerosis (SSc) has been suggested to cause exocrine pancreatic dysfunction. However, a case-control-based autopsy study failed to associate systemic sclerosis with any pancreatic histopathology. The primary objective of this study was to examine the exocrine pancreatic function in consecutive SSc patients in relation to an age- and sex-matched control group. A secondary objective was to relate exocrine pancreatic function to radiological, laboratory, and clinical SSc characteristics...
February 12, 2019: Arthritis Research & Therapy
Ken Min Chin, Damien M Y Tan, Norman H L Chan, Brian K P Goh
INTRODUCTION: Heterotopic pancreas (HP) is a relatively rare entity occurring in approximately 5% of the general population. It most commonly presents as an asymptomatic mass incidentally picked up on unrelated scans. HP most commonly occurs intra-abdominally, but has been known to occur in extra-abdominal sites such as the lung and brain. It is widely considered to bear little to no malignant potential. Difficulty and ambiguity in the diagnosis of HP commonly results in interventional dilemma and delay...
January 30, 2019: International Journal of Surgery Case Reports
Donal Cahill, Fernanda Zamboni, Maurice N Collins
Type 1 diabetes mellitus (T1DM) is characterized by hyperglycemia, owing to the loss of pancreatic β cells in response to an autoimmune reaction leading to a state of absolute insulin deficiency. T1DM treatment is shifting from exogenous insulin replacement therapy toward pancreatic β-cell replacement, to restore physiologically responsive insulin secretion to variations in blood glucose levels. β-cell replacement strategies include human whole pancreas transplantation, islet transplantation with cell encapsulation and bioengineered pancreas...
January 29, 2019: Academic Radiology
Barnini Banerjee, Rohit Gupta, Muralidhar Varma, Chiranjay Mukhopadhyay, Tushar Shaw
Nocardia asteroides complex and Nocardia brasiliensis are common etiological agents of disseminated nocardiosis among immunocompromised individuals. Here we reported an uncommon case of disseminated nocardiosis with the involvement of lung, brain, soft tissue & pancreas by a rarely isolated species Nocardia asiatica in a HIV infected individual. Diagnosis was initially misinterpreted as tuberculosis based on the clinical and radiological findings. The isolate was identified to the species level with a 16S rRNA gene analysis & in vitro susceptibility was done as resistance is not uncommon among them...
January 28, 2019: Journal of Infection and Public Health
(no author information available yet)
Fusion imaging allows exploitation of the strengths of all imaging modalities simultaneously, eliminating or minimizing the weaknesses of every single modality. Ultrasound (US) fusion imaging provides benefits in real time from both the dynamic information and spatial resolution of the normal US and the high-contrast resolution and wider field of view of the other imaging methods. US fusion imaging can also be associated with the use of different ultrasound techniques such as color Doppler US, elastography, and contrast-enhanced US (CEUS), for better localization and characterization of lesions...
January 28, 2019: Insights Into Imaging
Sarfaraz Hussein, Pujan Kandel, Candice W Bolan, Michael B Wallace, Ulas Bagci
Risk stratification (characterization) of tumors from radiology images can be more accurate and faster with computeraided diagnosis (CAD) tools. Tumor characterization through such tools can also enable non-invasive cancer staging, prognosis, and foster personalized treatment planning as a part of precision medicine. In this study, we propose both supervised and unsupervised machine learning strategies to improve tumor characterization. Our first approach is based on supervised learning for which we demonstrate significant gains with deep learning algorithms, particularly by utilizing a 3D Convolutional Neural Network and Transfer Learning...
January 23, 2019: IEEE Transactions on Medical Imaging
Marco Del Chiaro, Ross Beckman, Zeeshan Ateeb, Nicola Orsini, Neda Rezaee, Lindsey Manos, Roberto Valente, Chunhui Yuan, Ding Ding, Georgios A Margonis, Lingdi Yin, John L Cameron, Martin A Makary, Richard A Burkhart, Matthew J Weiss, Jin He, Urban Arnelo, Jun Yu, Christopher L Wolfgang
MINI: This retrospective analysis of 901 patients who underwent pancreatic resection for IPMN shows significant risk of malignancy associated with main duct dilatation greater than 5 mm. While previous studies and guidelines have focused on a 10 mm cutoff for criteria for resection, we provide evidence that lower levels of dilatation may warrant consideration for surgery as well. OBJECTIVE: The purpose of this study is to determine preoperative factors that are predictive of malignancy in patients undergoing pancreatic resection for intraductal papillary mucinous neoplasms (IPMN)...
January 18, 2019: Annals of Surgery
Sajan Jiv Singh Nagpal, Thoetchai Peeraphatdit, Shilpa Kala Sannapaneni, Ayush Sharma, Naoki Takahashi, Michael L Kendrick, Shounak Majumder, Santhi Swaroop Vege
BACKGROUND AND AIMS: Annular pancreas (AnnP) is a rare congenital abnormality that results from the presence of a complete or partial ring of pancreatic tissue surrounding the descending portion of the duodenum. While the clinical presentation and management of AnnP in neonates and infants has been well described, the complete spectrum of clinical presentation of AP in adults is not very clear. We aimed to describe the clinical spectrum of presentation and management of adult patients with AnnP...
January 3, 2019: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
Pietro Calcagno, Marco Lotti, Luca Campanati, Salvatore Greco, Rosangela Trezzi, Andrea Assolari, Elisa Vaterlini, Cristina Bertani, Niccolò Allievi, Michela Giulii Capponi
Ectopic pancreas is a rare embryological abnormality apparently not in association with others. Stomach and duodenum are the most common organs involved. Symptoms are nonspecific. Patients may complain of dyspepsia, abdominal pain or intestinal obstruction. Malignant evolution of ectopic pancreatic cells has been reported. Diagnosis can be very challenging due to the rarity of the disease and the absence of specific symptoms and radiological findings. We report two cases of young-adult men admitted to the emergency department due to acute upper gastro-intestinal and pancreatic symptoms...
November 8, 2018: Curēus
V A Chidambaram, C Robert, C S Y Anita, C Garry
IgG4-related disease is a newly described systemic autoimmune and allergic disease, characterized histologically by a fibroinflammatory response with IgG4 plasma cells. It was initially described as affecting the pancreas, but commonly involves the head and neck region as well. While a biopsy is essential for definitive diagnosis, cross sectional imaging may be the initial modality which may suggest this entity. We describe a case of pathologically proven IgG4 related disease which highlights some key radiologic features seen in this entity...
December 2018: Medical Journal of Malaysia
Naïk Vietti Violi, Tom Hilbert, Jessica A M Bastiaansen, Jean-Francois Knebel, Jean-Baptiste Ledoux, Alto Stemmer, Reto Meuli, Tobias Kober, Sabine Schmidt
BACKGROUND: Long acquisition times and motion sensitivity limit T2 mapping in the abdomen. Accelerated mapping at 3 T may allow for quantitative assessment of diffuse pancreatic disease in patients during free-breathing. PURPOSE: To test the feasibility of respiratory-triggered quantitative T2 analysis in the pancreas and correlate T2 -values with age, body mass index, pancreatic location, main pancreatic duct dilatation, and underlying pathology. STUDY TYPE: Retrospective single-center pilot study...
January 13, 2019: Journal of Magnetic Resonance Imaging: JMRI
Vidya C Shrikantaiah, Manjaunatha Basappa, Sangita Hazrika, Roopa Ravindranath
Portal vein provides about three-fourths of liver's blood supply. Portal vein is formed behind the neck of pancreas, at the level of the second lumbar vertebra and formed from the convergence of superior mesenteric and splenic veins. The purpose of this study is to review the normal distribution and variation, morphometry of portal vein and its branches for their implication in liver surgery and preoperative portal vein embolization. It is also helpful for radiologists while performing radiological procedures...
December 2018: Anatomy & Cell Biology
Adnan Salim, Sadia Jabbar, Farhan Ul Amin, Kashif Malik
BACKGROUND: Obstructive jaundice due to malignancies of the biliary tree, gall bladder and pancreas account for a significant number of patients managed by tertiary centres. Management options are curative or palliative, depending on disease stage. This study was performed to see the effectiveness of treatment modalities for these patients and eventual outcome. METHODS: This cross-sectional analytical study was conducted at the Department of Gastroenterology and Hepatology, Shaikh Zayed Hospital Lahore, from January 2015 to June 2016...
October 2018: Journal of Ayub Medical College, Abbottabad: JAMC
S Sallapan, N Z Abu Bakar, R Jarmin, N Masir, F Mohammed
INTRODUCTION: Primary pancreatic lymphomas are extremely rare. Clinically, primary pancreatic lymphoma mimics symptoms of carcinoma of the pancreatic head. Clinical and radiological features may overlap with other pancreatic conditions such as carcinoma, neuroendocrine tumours and autoimmune pancreatitis. CASE REPORT: We report a case of a 75-year-old man who presented with symptoms of obstructive jaundice. Ultrasonography and computed tomography (CT) showed an ill-defined lobulated soft tissue lesion at the head/uncinate process of the pancreas measuring 4...
December 2018: Malaysian Journal of Pathology
Muhammad Usman Tariq, Zubair Ahmad, Jamshid Abdul-Ghafar, Nasir Ud Din
Background: Serous cystadenomas of pancreas are rare benign epithelial neoplasms, which predominantly occur in the pancreatic body and tail of elderly females. Majority of these tumors have microcystic appearance. Macrocystic and solid variants have also been described. A number of more aggressive cystic pancreatic lesions are included in the differential diagnosis. Distinction from such lesions is important for optimal management. Objective: Our aim was to study the clinical and histological features of serous cystadenomas which would be helpful in making their correct diagnosis and understanding their behavior...
2018: Rare Tumors
Giovanni Marchegiani, Stefano Andrianello, Chiara Miatello, Tommaso Pollini, Erica Secchettin, Giorgia Tedesco, Mirko D'Onofrio, Giuseppe Malleo, Claudio Bassi, Roberto Salvia
BACKGROUND: The prevalence of symptoms in pancreatic cystic neoplasms (PCNs) is mainly based on retrospective surgical series. The aim of this study is to describe the actual prevalence of symptoms in PCNs under surveillance. METHODS: Patients with PCNs under surveillance observed from 2015 to 2017 were submitted to magnetic resonance imaging (MRI) and a specific interview. An identical survey was carried out on a control population matched for age, sex, and comorbidities in which any pancreatic disease was excluded by MRI...
December 12, 2018: Digestive Surgery
Ki Byung Song, Jaewoo Kwon, Young-Joo Lee, Dae Wook Hwang, Jae Hoon Lee, Sang Hyun Shin, Myung-Hwan Kim, Sung Koo Lee, Dong-Wan Seo, Sang Soo Lee, Do Hyun Park, Tae Jun Song, Guisuk Park, Yejong Park, Seung Jae Lee, Song Cheol Kim
BACKGROUND: Recently, laparoscopic distal pancreatectomy (LDP) has become the standard procedure for resection of left-sided pancreatic tumors. Fluid collection (FC) at the resection margin of the pancreatic stump after LDP is a frequent radiological finding. However, there have been few treatment guidelines and the optimal management for this clinical finding is unclear. The aim of present study is to define the incidence of FC and suggest the optimal management for FC after LDP. METHODS: A total of 1227 patients who underwent LDP between March 2005 and December 2015 were collected...
December 7, 2018: Surgical Endoscopy
Wouter H Kopp, Claar A T van Leeuwen, Hwai D Lam, Volkert A L Huurman, Johan W de Fijter, Alexander F Schaapherder, Andrzej G Baranski, Andries E Braat
Complete graft thrombosis is the leading cause of early graft loss following pancreas transplantation. Partial thrombosis is usually subclinical and discovered on routine imaging. Treatment options may vary in such cases. We describe the incidence and relevance of partial graft thrombosis in a large transplant center. All consecutive pancreas transplantation at our center (2004-2015) were included in this study. Radiological follow-up, type and quantity of thrombosis prophylaxis, complications and, graft and patient survival were collected...
December 7, 2018: Transplant International: Official Journal of the European Society for Organ Transplantation
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