Annie A Wu, Elizabeth D Thompson, John L Cameron, Jin He, Richard A Burkhart, William R Burns, Kelly J Lafaro, Christopher R Shubert, Marcia I Canto, Elliot K Fishman, Ralph H Hruban
The radiologic finding of focal stenosis of the main pancreatic duct is highly suggestive of pancreatic cancer. Even in the absence of a mass lesion, focal duct stenosis can lead to surgical resection of the affected portion of the pancreas. We present four patients with distinctive pathology associated with non-neoplastic focal stenosis of the main pancreatic duct. The pathology included stenosis of the pancreatic duct accompanied by wavy, acellular, serpentine-like fibrosis, chronic inflammation with foreign body-type giant cell reaction, and calcifications...
March 14, 2024: American Journal of Surgical Pathology