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Phrenic nerve

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https://read.qxmd.com/read/30766804/microsurgical-technique-for-concurrent-cervical-corpectomy-and-ventral-phrenic-nerve-access-in-the-rat
#1
Michael G Z Ghali
The phrenic nerve is useful to record as a motor output in studies investigating neural control of respiration. It may be accessed via dorsal or ventral microsurgical approaches. Since such studies frequently involve concurrent access to the spinal cord, the two approaches may be alternatively used, each with its own set of advantages and disadvantages. The dorsal approach permits easier exposure of the spinal cord via laminectomy, but, compared to the ventral approach, phrenic nerve access proves more challenging, and concurrent surgical access to the full complement of respiratory-related nerves (i...
2019: MethodsX
https://read.qxmd.com/read/30762662/bipolar-active-fixation-left-ventricular-lead-or-quadripolar-passive-fixation-lead-an-italian-multicenter-experience
#2
Matteo Ziacchi, Gabriele Giannola, Maurizio Lunati, Tommaso Infusino, Giovanni Luzzi, Roberto Rordorf, Domenico Pecora, Maria Grazia Bongiorni, Ermenegildo De Ruvo, Mauro Biffi
AIMS: About one-third of patients receiving cardiac resynchronization therapy (CRT) are not responders, due to either patient selection or technical issues. Left ventricular quadripolar passive fixation leads (QPL) and bipolar active fixation (BAF) leads have been designed to ensure a targeted left ventricular stimulation area, minimizing lead dislodgments and phrenic nerve stimulation (PNS). The aim was to compare real-world safety and efficacy of BAF (Attain Stability, Medtronic Plc...
February 11, 2019: Journal of Cardiovascular Medicine
https://read.qxmd.com/read/30756404/selective-reinnervation-using-phrenic-nerve-and-hypoglossal-nerve-for-bilateral-vocal-fold-paralysis
#3
Meng Li, Hongliang Zheng, Shicai Chen, Donghui Chen, Minhui Zhu
OBJECTIVE: To evaluate the extent of airway improvement and voice quality in patients with bilateral vocal fold paralysis (BVFP) who underwent selective laryngeal reinnervation surgery. METHODS: Seven patients with BVFP caused by thyroid surgeries were enrolled. They underwent selective laryngeal reinnervation surgery. Videostroboscopy data, voice perceptual data (grade [G]), acoustic data, laryngeal electromyography data, and pulmonary function test data were obtained preoperatively and postoperatively...
February 12, 2019: Laryngoscope
https://read.qxmd.com/read/30756393/shorter-cryoballoon-applications-times-do-not-effect-efficacy-and-result-in-less-phrenic-nerve-injury-results-of-the-randomized-123-study
#4
Marleen M D Molenaar, Carl C Timmermans, Tim Hesselink, Marcoen F Scholten, Rachel M A Ter Bekke, Justin G L M Luermans, Marjolein Brusse-Keizer, Karin Kraaier, Bernard Ten Haken, Jan G Grandjean, Kevin Vernooy, Jurren M van Opstal
BACKGROUND: The second generation cryoballoon significantly improves outcome of pulmonary vein (PV) isolation (PVI) but may cause more complications than the first generation. Currently no consensus regarding optimal cryoballoon application time exists. The 123-study aimed to assess the minimal cryoballoon application duration necessary to achieve PVI (primary endpoint) and the effect of application duration on prevention of phrenic nerve injury (PNI). METHODS: Patients <75 years of age with paroxysmal atrial fibrillation, normal PV anatomy and left atrial size <40cc/m² or <50mm, were randomized to two applications of different duration: "short" "medium" or "long"...
February 13, 2019: Pacing and Clinical Electrophysiology: PACE
https://read.qxmd.com/read/30753411/early-experience-of-thoracoscopic-vs-catheter-ablation-for-atrial-fibrillation
#5
Charles M Pearman, James Redfern, Emmanuel A Williams, Richard L Snowdon, Paul Modi, Mark C S Hall, Simon Modi, Johan E P Waktare, Saagar Mahida, Derick M Todd, Neeraj Mediratta, Dhiraj Gupta
Aims: Video-assisted thoracoscopic surgery (VATS) ablation has been advocated as a treatment option for non-paroxysmal atrial fibrillation (AF) in recent guidelines. Real-life data on its safety and efficacy during a centre's early experience are sparse. Methods and results: Thirty patients (28 persistent/longstanding persistent AF) underwent standalone VATS ablation for AF by an experienced thoracoscopic surgeon, with the first 20 cases proctored by external surgeons...
February 6, 2019: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/30746191/surgical-resection-for-advanced-thymic-malignancy-with-pulmonary-hilar-invasion-using-hemi-clamshell-approach
#6
Ayako Fujiwara, Soichiro Funaki, Naoko Ose, Takashi Kanou, Ryu Kanzaki, Masato Minami, Yasushi Shintani
Background: The hemi-clamshell (HCS) approach provides a wide anterior view of the mediastinum as well as outstanding exposure of the pulmonary hilum. Here, we evaluated the utility and outcomes of this approach in cases of advanced thymic malignancy with hilar invasion. Methods: We performed a retrospective analysis of 14 patients with thymic epithelial malignancy surgically resected with an HCS approach. All required lung resection because of suspected pulmonary hilar vessel invasion...
December 2018: Journal of Thoracic Disease
https://read.qxmd.com/read/30742849/an-arterially-perfused-brainstem-preparation-of-guinea-pig-to-study-central-mechanisms-of-airway-defense
#7
Mathias Dutschmann, Rishi Dhingra, Robin McAllen, Stuart B Mazzone, David G S Farmer
The perfused working heart brainstem preparation of rodents has become a widely used tool to study brainstem function. Here, we adapt this experimental technique for newborn guinea pigs (postnatal day 7-14) to develop a tool that enables investigation of airway defense mechanisms not observed in other rodents. The perfused guinea pig brainstem preparation generates a stable eupnea-like motor pattern recorded from the phrenic, recurrent laryngeal and intercostal nerves and basic cardio-respiratory reflexes, including the arterial chemoreceptor, the baroreceptor reflex...
February 8, 2019: Journal of Neuroscience Methods
https://read.qxmd.com/read/30712645/low-complication-rates-using-high-power-45-50-w-for-short-duration-for-atrial-fibrillation-ablations
#8
Roger A Winkle, Sanghamitra Mohanty, Rob A Patrawala, R Hardwin Mead, Melissa H Kong, Gregory Engel, Jonathan Salcedo, Chintan G Trivedi, Carola Gianni, Pierre Jais, Andrea Natale, John D Day
BACKGROUND: Many centers use radiofrequency (RF) energy at 25-35 W for 30-60 seconds. There is a safety concern about using higher power, especially on the posterior wall. OBJECTIVE: The purpose of this study was to examine complication rates for atrial fibrillation (AF) ablations performed with high-power, short-duration RF energy. METHODS: We examined the complication rates of 4 experienced centers performing AF ablations at RF powers from 45-50 W for 2-15 seconds per lesion...
February 2019: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://read.qxmd.com/read/30711345/-bilateral-diaphragmatic-palsy-due-to-lyme-neuroborreliosis
#9
C Bon, E Krim, G Colin, W Picard, V Gaborieau, D Gourcerol, C Raherison
INTRODUCTION: Lyme disease is not uncommon and can sometimes progress to neurological complications. We report here an unusual case of bilateral diaphragmatic paralysis secondary to Lyme neuroborreliosis. CASE REPORT: A 79-year-old man was admitted to the intensive care unit for acute respiratory distress requiring intubation and the long-term use of nocturnal non-invasive ventilation. Three months beforehand he had been bitten by a tick and developed erythema migrans which was treated with Doxycycline for 10 days...
January 30, 2019: Revue des Maladies Respiratoires
https://read.qxmd.com/read/30697688/diaphragm-sparing-effect-of-the-infraclavicular-subomohyoid-block-vs-low-volume-interscalene-block-a-randomized-blinded-study
#10
Ahmad M Taha, Nagib A Yurdi, Mohamed I Elahl, Ahmed M Abd-Elmaksoud
BACKGROUND: Both low volume interscalene and infraclavicular-subomohyoid blocks were suggested to provide shoulder analgesia with low risk of phrenic nerve block. The aim of this study was to compare the frequency of the phrenic nerve block between these two techniques. METHOD: Seventy-two patients scheduled for shoulder arthroscopy were included in this randomized controlled blind study. Before induction of general anesthesia, patients received low volume interscalene block using 5 mL of ropivacaine 0...
January 30, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30693197/atrial-fibrillation-resulting-from-superior-vena-cava-drivers-addressed-with-cryoballoon-ablation-late-reconnection-at-the-site-of-phrenic-nerve-pacing-catheter
#11
Ben Ng, Rahn Ilsar, Mark A McGuire, Suresh Singarayar
No abstract text is available yet for this article.
January 2019: HeartRhythm Case Reports
https://read.qxmd.com/read/30692766/prospective-hospital-based-clinical-and-electrophysiological-evaluation-of-acute-organophosphate-poisoning
#12
Karkal Ravishankar Naik, Aralikatte Onkarappa Saroja, Nagabushan Hesarur, Rekha Satish Patil
Introduction: Acute organophosphate (OP) poisoning is one of the most common poisoning causing significant morbidity and mortality in developing countries. Acute cholinergic manifestations predominate with many patients requiring intensive care management and ventilator support. Nerve conduction studies including repetitive nerve stimulation can evaluate the altered neuromuscular transmission and peripheral nerve function by OPs. Objective: To evaluate the electrophysiological abnormalities in patients with acute OP poisoning and correlate with clinical status...
January 2019: Annals of Indian Academy of Neurology
https://read.qxmd.com/read/30682521/interleukin-6-and-amyotrophic-lateral-sclerosis
#13
Ana Pronto-Laborinho, Susana Pinto, Marta Gromicho, Mariana Pereira, Michael Swash, Mamede de Carvalho
BACKGROUND: IL-6 is an inflammatory cytokine that is a possible factor in progression of the disease. We have investigated venous blood levels of IL-6 in controls and ALS patients in relation to clinical staging and respiratory function. METHODS: We studied 82 patients with ALS and 43 age and gender-matched healthy control subjects. Blood was drawn at the same time of day in the mornings to avoid diurnal variation. IL-6 levels were estimated according to a fixed protocol...
January 16, 2019: Journal of the Neurological Sciences
https://read.qxmd.com/read/30682440/prophylactic-potential-of-memantine-against-soman-poisoning-in-rats
#14
Miloš P Stojiljković, Ranko Škrbić, Milan Jokanović, Dubravko Bokonjić, Vesna Kilibarda, Maja Vulović
BACKGROUND: Carbamates physostigmine and pyridostigmine have been used as a pretreatment against poisoning with nerve agents in order to reversibly inhibit and thus protect from irreversible inhibition a portion of acetylcholinesterase (AChE) in brain and respiratory muscles that is crucial for survival. Memantine, an adamantine derivative, has emerged as a promising alternative to carbamates, since it prevented the fasciculations and skeletal muscle necrosis induced by carbamates and organophosphates, including nerve agents...
January 22, 2019: Toxicology
https://read.qxmd.com/read/30680764/comparison-of-the-medtronic-selectsecure-and-conventional-pacing-leads-long-term-follow-up-in-a-multicenter-pediatric-and-congenital-cohort
#15
Jeffrey P Moak, Ian H Law, Martin J LaPage, Frank Fish, Ira Shatty, Anne M Dubin, Akash Patel, Peter Fishbach, Nicole Cain, Christopher Johnsrude, Charles I Berul, Aminata Bangoura, Sridhar Hanumanthaiah, Robert McCarter
INTRODUCTION: The Medtronic SelectSecure™ pacing lead (SS) has theoretical advantages compared to conventional (C) transvenous pacing leads (PL). The study purpose was to determine whether differences in electrical function and lead survival exist between these PL in a large data set of pediatric and congenital patients. METHODS: A multicenter historical longitudinal cohort study was performed comparing SS and CPL performance over a 72-month follow-up (FU). Ten centers provided data for both SS and CPL, matched for age, implanted pacing chamber, time period of implantation, and presence of heart disease...
January 25, 2019: Pacing and Clinical Electrophysiology: PACE
https://read.qxmd.com/read/30678790/phrenic-nerve-limitation-during-epicardial-catheter-ablation-of-ventricular-tachycardia
#16
Kenji Okubo, Nicola Trevisi, Luca Foppoli, Caterina Bisceglia, Francesca Baratto, Lorenzo Gigli, Giuseppe D'Angelo, Andrea Radinovic, Manuela Cireddu, Gabriele Paglino, Patrizio Mazzone, Paolo Della Bella
OBJECTIVES: This study sought to investigate the incidence of phrenic nerve (PN) limitation and the utility of displacing the PN with a balloon. BACKGROUND: The PN can limit the epicardial ablation of ventricular tachycardia (VT). METHODS: From 2010 to 2017, 363 patients undergoing VT epicardial ablation at a single center were studied. Before the ablation, we used high output (20-mA) pacing maneuvers to verify the course of the PN. When we observed its capture, we used 1 of 3 different approaches to protect it: 1) non-balloon strategy (nerve-sparing ablation); 2) PN displacement with a small balloon (6 mm × 20 mm); or 3) PN displacement with a large balloon (20 mm × 45 mm)...
January 2019: JACC. Clinical Electrophysiology
https://read.qxmd.com/read/30646591/effects-of-two-fractions-of-swietenia-macrophylla-and-catechin-on-muscle-damage-induced-by-bothropsvenom-and-pla%C3%A2
#17
Silvia Posada Arias, Berardo de Jesús Rodríguez, Tatiana Lobo-Echeverri, Raphael Shezaro Ramos, Stephen Hyslop, VitelbinaNúñez Rangel
Plant natural products can attenuate the myonecrosis caused by Bothrops snake venom and their phospholipases A₂ (PLA₂). In this study, we evaluated the effects of two fractions (F4 and F6) from Swietenia macrophylla and purified catechin on the muscle damage caused by a myotoxic PLA₂ from Colombian Bothrops asper venom (BaColPLA₂) in mice and by Bothrops marmoratus venom from Brazil in mouse phrenic nerve-diaphragm muscle (PND) preparations in vitro. Male mice were injected with PLA₂ (50 µg) in the absence or presence of F4, F6, and catechin, in the gastrocnemius muscle and then killed 3, 7, 14, and 28 h later for histopathological analysis of myonecrosis, leukocyte infiltration, and the presence of collagen...
January 14, 2019: Toxins
https://read.qxmd.com/read/30640655/effect-of-local-anesthetic-volume-20-ml-vs-30-ml-ropivacaine-on-electromyography-of-the-diaphragm-and-pulmonary-function-after-ultrasound-guided-supraclavicular-brachial-plexus-block-a-randomized-controlled-trial
#18
Xiuxia Bao, Juanjuan Huang, Haorong Feng, Yuying Qian, Yajie Wang, Qunying Zhang, Huansheng Hu, Xianghe Wang
BACKGROUND AND OBJECTIVES: Diaphragmatic paralysis following supraclavicular brachial plexus block (SCBPB) is ascribed to phrenic nerve palsy. This study investigated the effect of 2 volumes of 0.375% ropivacaine on efficacy of block as a surgical anesthetic and as an analgesic and examined diaphragm compound muscle action potentials (CMAPs) and pulmonary function before and after SCBPB. METHODS: Eighty patients scheduled for removal of hardware for internal fixation after healing of an upper limb fracture distal to the shoulder were randomized to receive ultrasound-guided SCBPC for surgical anesthesia with 20 mL (Group A) or 30 mL (Group B) 0...
January 2019: Regional Anesthesia and Pain Medicine
https://read.qxmd.com/read/30639504/circulatory-control-of-phrenic-motor-plasticity
#19
Raphael R Perim, Gordon S Mitchell
Acute intermittent hypoxia (AIH) elicits distinct mechanisms of phrenic motor plasticity initiated by brainstem neural network activation versus local (spinal) tissue hypoxia. With moderate AIH (mAIH), hypoxemia activates the carotid body chemoreceptors and (subsequently) brainstem neural networks associated with the peripheral chemoreflex, including medullary raphe serotonergic neurons. Serotonin release and receptor activation in the phrenic motor nucleus then elicits phrenic long-term facilitation (pLTF)...
January 10, 2019: Respiratory Physiology & Neurobiology
https://read.qxmd.com/read/30636343/differential-age-gender-and-side-dependency-of-vagus-spinal-accessory-and-phrenic-nerve-calibers-detected-with-precise-ultrasonography-measures
#20
Uwe Walter, Panagiota Tsiberidou
INTRODUCTION: The standard ultrasonographic measurement tools (trace, ellipse) of cross-sectional areas (CSA) of very small nerves typically yield rough measures in full square millimeters. METHODS: In 70 volunteers, the elliptically shaped CSAs of mid-cervical vagus, accessory and phrenic nerves were estimated with three methods: two on-board tools (area tracing, ellipse fitting) and an off-line calculation of the CSA after on-board measuring of its long-axis and short-axis diameters both displayed with 1-2 digits following the decimal point...
January 13, 2019: Muscle & Nerve
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