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M Cameli, F M Righini, S Sparla, D Tacchini, A Dokollari, C G Sassi, C Di Tommaso, V Curci, S Censini, E Incampo, F Cassano, G Droandi, S Bernazzali, M Focardi, F Ietta, L Sartiani, R Romagnoli, G Marotta, A Mugelli, L Paulesu, G Sani, P Tanganelli, M Maccherini, S Mondillo
BACKGROUND: Recent studies have challenged the dogma that the adult heart is a postmitotic organ and raise the possibility of the existence of resident cardiac stem cells (CSCs). Our study aimed to explore if these CSCs are present in the "ventricular tip" obtained during left ventricular assist device (LVAD) implantation from patients with end-stage heart failure (HF) and the relationship with LV dysfunctional area extent. METHODS: Four consecutive patients with ischemic cardiomyopathy and end-stage HF submitted to LVAD implantation were studied...
March 2016: Transplantation Proceedings
J Kasalický, J Ressl, J Fabián, P Jebavý, V Stanĕk, A Belán
Eighteen men with myocardial infarction in their history and without signs of heart failure were investigated at rest and during standard supine exercise. In nine patients aneurysma or diskinesis of the left ventricular wall were found. The left ventricular end-diastolic volume was determined from the wash-out of 133Xe injected into the left ventricle by means of precordial scintillation counting. During exercise the cardiac index rose owing to acceleration of the heart rate, whereas the stroke index remained unchanged, and the left ventricular work and stroke indices increased...
1977: Cor et Vasa
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