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Degeration disease

Maxime W C Rousseaux, Gabriel E Vázquez-Vélez, Ismael Al-Ramahi, Hyun-Hwan Jeong, Aleksandar Bajić, Jean-Pierre Revelli, Hui Ye, Emily T Phan, Jennifer M Deger, Alma M Perez, Ji-Yoen Kim, Laura A Lavery, Qikia Xu, Mamie Z Li, Hyojin Kang, Jean J Kim, Joshua M Shulman, Thomas F Westbrook, Stephen J Elledge, Zhandong Liu, Juan Botas, Huda Y Zoghbi
Accumulation of α-Synuclein (α-Syn) causes Parkinson's disease (PD) as well as other synucleopathies. α-Syn is the major component of Lewy bodies and Lewy neurites, the proteinaceous aggregates that are a hallmark of sporadic PD. In familial forms of PD, mutations or copy number variations in SNCA (the α-Syn gene) result in a net increase of its protein levels. Furthermore, common risk variants tied to PD are associated with small increases of wild-type α-Syn levels. These findings are further bolstered by animal studies which show that overexpression of α-Syn is sufficient to cause PD-like features...
October 24, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Serpil Muge Deger, Jennifer R Hewlett, Jorge Gamboa, Charles D Ellis, Adriana M Hung, Edward D Siew, Cindy Mamnungu, Feng Sha, Aihua Bian, Thomas G Stewart, Naji N Abumrad, T Alp Ikizler
Maintenance hemodialysis (MHD) patients display significant nutritional abnormalities. Insulin is an anabolic hormone with direct effects on skeletal muscle (SM). We examined the anabolic actions of insulin, whole-body (WB) and SM protein turnover, in 33 MHD patients and 17 participants without kidney disease using hyperinsulinemic euglycemic euaminoacidemic (dual) clamp. Gluteal muscle biopsies were obtained before and after the dual-clamp. At baseline, WB protein synthesis and breakdown rates were similar in MHD patients...
June 12, 2018: American Journal of Physiology. Endocrinology and Metabolism
Katherine N Bachmann, Serpil Muge Deger, Aseel Alsouqi, Shi Huang, Meng Xu, Jane F Ferguson, Yan Ru Su, Kevin D Niswender, T Alp Ikizler, Thomas J Wang
BACKGROUND: The natriuretic peptide hormones play an important role in salt and blood pressure regulation. In observational studies, obesity and insulin resistance have been consistently associated with lower concentrations of natriuretic peptides. It has been proposed that insulin influences natriuretic peptide production. OBJECTIVE: We sought to determine the acute effects of insulin administration on natriuretic peptide concentrations. METHODS: 31 men and women (11 lean, 10 overweight, and 10 obese), ages 30-70 years, without cardiovascular disease or overt diabetes underwent a hyperinsulinemic-euglycemic insulin clamp...
2018: PloS One
Orhan Uzun, Mürşit Dinçer, Aziz Serkan Senger, Kamuran Cumhur Değer, Mustafa Duman
No abstract text is available yet for this article.
May 2018: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
Martina Maurelli, Paolo Gisondi, Giampiero Girolomoni
BACKGROUND: Kyrle's disease (KD) is a primary perforating dermatosis that affects more commonly 30-50 year old females, and clinically characterized by pruritic hyperkeratotic and ulcerated nodules, papules and plaques, localized on extensor surface of upper and lower limbs, and on the trunk. OBJECTIVE: To determine the effectiveness of the treatment with oral isotretinoin in KD. METHODS: We present the case of a 63-year-old woman with hyperkeratotic, erythematous-brown nodules and plaques localized on arms and legs, intensely itching; some lesions were ulcerated and discharging...
September 2018: Journal of Dermatological Treatment
Ebubekir Gündeş, Hüseyin Çiyiltepe, Ulaş Aday, Durmuş Ali Çetin, Aziz Serkan Senger, Orhan Uzun, Kamuran Cumhur Değer, Mustafa Duman, Erdal Polat
Objective: Our aim in this study was to present the cases of our patients who contracted colonic perforation during elective colonoscopy and became emergency cases; we also discuss treatment modalities along with literature reports on the subject. Material and Methods: Cases of patients who contracted iatrogenic colonic perforation following endoscopy of the colorectal system between January 2009 and December 2015 at Kartal Koşuyolu Yüksek İhtisas Training and Research Hospital's Endoscopy Unit were reviewed retrospectively...
2017: Turkish Journal of Surgery
Serpil M Deger, Adriana M Hung, Jorge L Gamboa, Edward D Siew, Charles D Ellis, Cindy Booker, Feng Sha, Haiming Li, Aihua Bian, Thomas G Stewart, Roy Zent, William E Mitch, Naji N Abumrad, T Alp Ikizler
BACKGROUND: Systemic inflammation and muscle wasting are highly prevalent and coexist in patients on maintenance hemodialysis (MHD). We aimed to determine the effects of systemic inflammation on skeletal muscle protein metabolism in MHD patients. METHODS: Whole body and skeletal muscle protein turnover were assessed by stable isotope kinetic studies. We incorporated expressions of E1, E214K, E3αI, E3αII, MuRF-1, and atrogin-1 in skeletal muscle tissue from integrin β1 gene KO CKD mice models...
November 16, 2017: JCI Insight
Vermi Değerli, Tanzer Korkmaz, Hülya Mollamehmetoğlu, Cem Ertan
Background/aim: The aim of our study was to emphasize the importance of routine bedside biliary ultrasonography (USG) for the differential diagnosis of biliary tract disorders in patients admitted with acute isolated epigastric pain. Materials and methods: Adult patients who were admitted to the emergency department with acute isolated epigastric pain were included in the study. Emergency residents (ERs) were asked whether they planned to perform biliary USG during the initial evaluation and following diagnosis/treatment (secondary evaluation) of these patients...
August 23, 2017: Turkish Journal of Medical Sciences
Huseyin Gursoy, Mustafa Deger Bilgec, Nazmiye Erol, Hikmet Basmak, Ertugrul Colak
OBJECTIVE: To analyze posterior segment findings in term and premature infants using the RetCam image database. METHODS: RetCam images taken of infants born between January 2012 and December 2015 were reviewed. Group 1 included infants with posterior segment findings other than retinopathy of prematurity (ROP). Group 2 included infants with mild-to-severe ROP. The baseline characteristics, anterior segment findings, and percentage of infants who received treatment were compared among the 2 groups...
October 2018: International Ophthalmology
Saltuk Bugra Kaya, Seyda Deger, Suleyman Savas Hacievliyagil, Zeynep Ayfer Aytemur
A 66-year-old male patient was referred to our clinic with severe pneumonia. Bronchoscopy was performed due to clinical worsening despite antibiotics and diuretic therapy, respiratory failure and radiographic progression. Because bacterial cultures of the bronchoalveolar lavage fluid were negative and after using amiodarone for almost one month, we eliminated amiodarone from his medication regimen due to suspicion of amiodarone toxicity. Accordingly, we also initiated systemic steroid therapy. Chest X-ray done after 72 hours showed a significant resolution of lung consolidations and the patient exhibited significant clinical improvement, with decline of his oxygen requirements...
March 2017: Revista da Associação Médica Brasileira
Vermi Degerli, Isil Ergin, Fulya Yilmaz Duran, Mehmet Akif Ustuner, Ozgur Duran
Objective. Acute mesenteric ischemia (AMI) is a disease, usually seen in elderly people and accompanied by comorbid diseases. Mean platelet volume (MPV), the significant indicator of platelet activation and function, is associated with AMI. In this study, we considered that we can use MPV as a reliable indicator in the diagnosis of AMI. Methods. This study was conducted among AMI patients with two control groups. Age, gender, MPV, platelet count, concomitant diseases, abdominal computed tomography, and patient outcomes were recorded for evaluation...
2016: BioMed Research International
A Melander, J Olsson, G Lindberg, A Salzman, T Howard, P Stang, E Lydick, A Emslie-Smith, D I R Boyle, J M M Evans, T M Macdonald, J Bain, F Sullivan, C Juhl, N Pørksen, J Sturis, M Hollingdal, S Pincus, J Veldhuis, A Dejgaard, O Schmitz, J S Kristensen, K B Frandsen, Th Bayer, P Müller, B E Dunning, S Paladini, C Gutierrez, R Deacon, M Valentin, G Grunberger, W M Weston, R Patwardhan, E B Rappaport, L A Sargeant, N J Wareham, K T Khaw, Björn Zethelius, Hans Lithell, C Nicholas Hales, Christian Berne, H-M Lakka, L Oksanen, T-P Tuomainen, K Kontula, J T Salonen, J M Dekker, P de Boks, F de Vegt, C D A Stehouwer, G Nijpels, L M Bouter, R J Heine, G Bruno, P Cavallo-Perin, G Bargero, N D'Errico, M Borra, G Macchia, G Pagano, R W Newton, D A Ruta, J P New, C Wallace, M A Roxburgh, R J Young, N J A Vaughan, P Elliott, G Brennan, M Devers, R MacAlpine, D Steinke, D H Lawson, B Decallonne, K Casteels, C Gysemans, R Bouillon, C Mathieu, Thomas Linn, Christine Strate, Kerstin Schneider, D P Funda, M Jirsa, H Kozáková, A Kaas, O Kofronová, H Tlaskalová-Hogenová, K Buschard, H Wanka, A Hartmann, B Kuttler, S B Rasmussen, T S Sørensen, H Markholst, J S Petersen, D Karounos, T Dyrberg, J G Mabley, G Haskó, C Szabó, J Seissler, T B T Nguyen, H Steinbrenner, W A Scherbaum, R Cipriani, A Gabriele, M Sensi, L Guidobaldi, F Pantellini, M G Cerrito, S Scarpa, U Di Mario, S Morano, G Ceolotto, E Iori, E Baritono, S Del Prato, A Semplicini, R Trevisan, G Zerbini, G Meregalli, V Asnaghi, F Tentori, A Maestroni, R Mangili, C Marescotti, M Vedovato, A Tiengo, J Tadjieva, B N Mankovsky, S Van Aken, A Raes, J Vande Walle, D Matthys, M Craen, H P Hansen, S S Lund, P Rossing, T Jensen, H-H Parving, S Andersen, L Tarnow, B V Hansen, C Trautner, B Haastert, N Ennenbach, S Willich, Á Gy Tabák, T J Orchard, J Spranger, K T Preissner, H Schatz, A Pfeiffer, A Cantón, R Burgos, C Hernández, A Lecube, J Mesa, R M Segura, C Mateo, R Simó, L Fathallah, D A Greene, I Obrosova, R E Gilbert, D J Kelly, A J Cox, J L Berka-Wilkinson, H R Taylor, S Panagiotopoulos, V Lee, G Jerums, M E Cooper, G A Hitman, E Aganna, W B Ogunkolade, M Rema, R Deepa, C S Shanthi-Rani, K Barakat, T R Kumarajeewa, P G Cassell, M F McDermott, V Mohan, K Ways, S Bursell, T Devries, J Woodworth, C Alatorre, G King, L P Aiello, A E Karisen, D Pavlovic, K Nielsen, J Jensen, H U Andersen, F Pociot, T Mandrup-Poulsen, D L Eizirik, J Nerup, S Lortz, M Tiedge, S Lenzen, F J Lally, A J Bone, M I Darville, Y-S Ho, J Sternesjö, S Sandler, M-C Chen, F Schuit, D G Pipeleers, S Merezak, A Hardikar, J J Hoet, C Remacle, B Reusens, B Bréant, A Garofano, P Czernichow, N Kubota, Y Terauchi, H Miki, H Tamemoto, T Yamauchi, R Nakano, K Komeda, K Eto, K Tobe, S Kimura, T Kadowaki, T Ide, K Murakami, M Tsunoda, T Mochizuki, S E Ozanne, B T Nave, C L Wang, M W Dorling, C J Petry, S J Koopmans, C van der Bent, I Que, J K Radder, E Sebokova, A K Sana, I Klimes, N Ruderman, L Morviducci, L Pastore, S Morelli, E Sagratella, D Zorretta, A Buongiomo, G Tamburrano, A Giaccari, Sabina Martinenghi, Gabriella Cusella De Angelis, Flavio Ravasi, Francesco Bifari, Claudio Bordignon, Luca Falqui, A Kessler, O Dransfeld, S Sasson, E Tomas, A Zorzano, J Eckel, P Thorsby, A M Rosenfalck, L Kjems, K F Hanssen, S Madsbad, K I Birkeland, M Hamilton-Wessler, J Markussen, R N Bergman, V Melki, H Hanaire-Broutin, S Bessières-Lacombe, J-P Tauber, P D Home, A Lindholm, A Riis, J Rosenstock, S Schwartz, C Clark, M Edwards, D Donley, P Swift, H B Mortensen, H Lynggaard, P Hougaard, C A Cull, H A W Neil, V Frighi, S E Manley, R R Holman, R C Turner, G Steiner, W A Davis, T Weeraratna, D G Bruce, T M E Davis, B Vergès, L Duvillard, F Pont, E Florentin, Ph Gambert, B Benko, S Ljubić, Z Turk, M Granić, W März, H Wollschläger, G Klein, A Neiss, M Wehling, S J Huxtable, P J Saker, M Walker, T M Frayling, J C Levy, S O'Rahilly, A T Hattersley, M I McCarthy, A Orecchio, A Giacchini, R Dominici, G Canettieri, B Trinti, M Zani, M Andreoli, S Sciacchitano, A M de Silva, K Whitecross, J Pasco, M Kotowicz, G Nicholson, P Zimmet, E J Boyko, G R Collier, L Frittitta, A Pizzuti, A Argiolas, S Graci, I D Goldfine, M Bozzali, T Ercolino, B Costanzo, L Iacoviello, V Tassi, V Trischitta, M Wauters, T Rankinen, I Mertens, M Chagnon, C Bouchard, L Van Gaal, K Sivenius, R Valve, V Hakkarainen, L Niskanen, M Laakso, M Uusitupa, N Beridze, M Japaridze, R Kurashvili, M Dundua, G Kebuladze, N Kazakhashvili, B Offley-Shore, B Thomas, K Ghebremeskel, M Crawford, C Lowy, Ulf J Eriksson, C Martin Simán, Bert Wisse, Adriana C Gittenberger-de Groot, P Wentzel, U J Eriksson, E Wender-Ożegowska, K Drews, R Biczysko, A Bronisz, D Rość, A Graczykowska-Koczorowska, M Kotschy, A Sokup, K D Kohnert, W Besch, J Strese, U Frick, E Zander, W Kemer, J Škrha, J Kvasnička, B Kalvodová, J Hilgertová, K Schatteman, F Goossens, S Scharpé, I De Leeuw, D Hendriks, I N Legakis, D Panayiotou, Th D Mountokalakis, M D Enderle, P Beckmann, B Balletshofer, K Rittig, E Maerker, A Volk, C Meisner, S Jacob, S Matthaei, H U Häring, K Rett, K Ueda, T Nakagawa, Y Shimajiri, M Kokawa, E Matsumoto, H Sasaki, T Sanke, K Nanjo, Caroline M McKinnon, Wendy M Macfarlane, Kevin Docherty, N Furukawa, T Shirotani, H Kishikawa, K Kaneko, E Araki, M Shichiri, M Prentki, R Roduit, S Susini, J Buteau, A M Ejrnæs, N Aa Andersen, M Osterhoff, M Möhlig, J Ortmann, F Bikashaghi, C Mayer, F Bikashagi, M T Ackermans, A M Pereira Arias, P H L T Bisschop, E Endert, H P Sauerwein, J A Romijn, A Gastaldelli, S Baldi, M Pettiti, A Natali, S Frascerra, S Camastra, E Toschi, E Ferrannini, H Stingl, M Krssak, M G Bischof, M Krebs, C Fürnsinn, P Nowotny, W Waldhäusl, M Roden, M Neeft, A J Meijer, P Båvenholm, J Pigon, S Efendic, T Kästenbauer, S Sauseng, G Sokol, M Auinger, K Irsigler, C A Abbott, A L Carrington, B Faragher, J Kulkarni, E R E Van Ross, A J M Boulton, D G Armstrong, S Hadi, H C Nguyen, L B Harkless, A Jirkovská, P Kasalicky, J Hosová, J Skibova, L Uccioli, A Caselli, C Giacomozzi, V Macellari, L Giurato, L Lardieri, G Menzinger, H T Pham, B I Rosenblum, T E Lyons, J M Giurini, P Smakowski, J S Chrzan, G M Habershaw, A Veves, A M Foster, M Bates, M Doxford, M E Edmonds, O Kecha, R Winkler, H Martens, J Collette, P J Lefèbvre, D Greiner, V Geenen, C Atlan-Gepner, M Naspetti, R Valéro, M Barad, F Lepault, B Vialettes, P Naquet, B de Galan, M G Netea, N Hancu, P Smits, J W M Van der Meer, T Osterbye, K H Jørgensen, J Tranum-Jensen, P Fredman, M Høy, K Bokvist, H L Olsen, T Horn, J Gromada, R Laub, T Lohmann, H J Hahn, T Adler, F Emmrich, A M Rabuazzo, R Lupi, F Dotta, G Patanè, L Marselli, M Realacci, S Piro, S Del Guerra, C Santangelo, R Navalesi, F Purrello, P Marchetti, P de Vos, L Visser, B J de Haan, P Klok, R van Schilfgaarde, S Poppema, J-H Juang, C-H Kuo, B R-S Hsu, V Nacher, M Pérez, M Biarnés, M Raurell, J Soler, E Montanya, R Ritzel, J Maubach, M Büsing, T Becker, J Klempnauer, K Hücking, W H Schmiegel, M A Nauck, P Bouček, F Saudek, M Adamec, R Kožitarová, T Jedináková, Z Vlasáková, J Skibová, V Bartoš, P Maffi, F Bertuzzi, L Aldrighetti, M V Taglietti, A Castelnuovo, G Pozza, V Di Carlo, A Secchi, G Renier, J-C Mamputu, J S Gillespie, D McMaster, C Mercer, E R Trimble, M Lecomte, E Véricel, C Paget, D Ruggiero, M Lagarde, N Wiernsperger, F Pricci, G Leto, L Amadio, S Cordone, C Iacobini, S Catalano, F Violi, C M Rotella, G Pugliese, A Zicari, R Gradini, P Sale, L Pala, B Cresci, S Giannini, C Manuelli, G Dahlfors, H J Arnqvist, C Gonelle-Gispert, P A Halnan, K Sadoul, S Wolter, J Lang, T Niwa, W Yu, H Hidaka, T Senda, I Niki, T Fukasawa, E Renstrom, S Barg, E Seward, P Rorsman, G A Rutter, M Molinete, V Lilla, M Ravazzola, P A Halban, A M Efanov, A M Bertorello, S V Zaitsev, J Zwiller, P-O Berggren, A MŞengül, F Salman, M Sargrn, E Özer, K Karşidaǧ, S Salman, S Gedik, I Satman, N Dinççaǧ, M T Yılmaz, A Lloyd, P K Hopkinson, M A Testa, L Blonde, R R Turner, J Hayes, D C Simonson, N C W van der Ven, C H C Lubach, F J Snoek, E D Mollema, H M van der Ploeg, T Danne, H Hoey, H McGee, H Fitzgerald, B Lernmark, G Thernlund, K Fredin, B Hägglöf, R Lugari, C Dell'Anna, D Ugolotti, A Dei Cas, A L Barilli, L Sard, B Marani, M Iotti, R Zandomeneghi, A Gnudi, L L Kjems, Aa Volund, M Toft-Nielsen, M B Damholt, L Hilsted, T E Hughes, T Krarup, J J Holst, A Young, A Gottlieb, M Fineman, O Kolterman, J Cancelas, J A García-Martínez, M L Villanueva-Peñacarrillo, I Valverde, W J Malaisse, K Filipsson, B Ahrén, B Balkan, L Kwasnik, B Battle, X Li, J M Egan, A R Clocquet, D Elahi, E Petrella, K Pricket, K F Petersen, J T Sullivan, J M Amatruda, J N Livingston, G I Shulman, E-J Freyse, S Knospe, K Glund, H-U Demuth, D Walker, R A Malik, M Reljanovic, A Barada, Z Milicevic, Cees J Tack, David S Goldstein, C Van Huysen, M J Stevens, X Cao, G Sundkvist, L-B Dahlin, K-F Eriksson, I Rosén, S A Lattimer, A A F Sima, K Sullivan, J E Shaw, M P de Courten, P Z Zimmet, P Gourdy, J B Ruidavets, D Arveiler, Ph Amouyel, A Bingham, J P Tauber, K S L Lam, N M S Wat, T H Lam, E D Janus, P de Pablos, F Rodriguez, J Martínez, V Sánchez, C Santana, I García, A Macías, K Levin, O Hother-Nielsen, J E Henriksen, H Beck-Nielsen, K Brechtel, J Machann, M Koch, M Nielsen, K Löblein, R Becker, M Denignger, W Renn, F Machicao, C D Claussen, F Schick, F Diraison, P Moulin, M Beylot, P Thams, K Capito, Lena Eliasson, Sebastian Barg, Sven Göpel, Takahiro Kanno, Erik Renström, P Meda, A Charollais, A Gjnovci, A Calabrese, A Wonkam, D Caton, L Wisznievski, V Serre, F Cogne, J Bauquis, D Bosco, J Huarte, P Herrera, C F Gotfredsen, B Vessby, B Manuel Y Keenoy, W Engelen, J Vertommen, S Schrans, A Louheranta, J Lindström, J Tuomilehto, K R Segal, S Heymsfield, J Hauptman, M Boldrin, C Lucas, A Pandolfi, D Cetrullo, R Polishchuck, M Alberta, G Pellegrini, A Calafiore, E Vitacolonna, F Capani, A Consoli, C M Halleux, E F Gillot, S M Brichard, M Van der Planken, B Corthouts, F Peiffer, D Scholten, M Walke, R Assert, V Pirags, K L Pedula, T A Hillier, J B Brown, S A Santini, G Marra, P Cotroneo, A Manto, M A S Di Leo, S Di Gregorio, A Tordi, D Pitocco, V Ruotolo, G Ghirlanda, T Temelkova-Kurktschiev, F Schaper, C Koehler, E Henkel, M Hanefeld, L Mancini, F Citterio, A Cotroneo, S Ceroone, M Castagneto, S M Rajbhandari, M T Dent, M E Plater, N D Harris, S Tesfaye, J D Ward, O Dupuy, H Mayaudon, S Lecoules, B Bauduceau, M Palou, O Farret, C Molinié, R Antonelli-Incalzi, L Fuso, A Giordano, M L Calcagni, L Todaro, S Basso, L M Tramaglino, L Troncone, R Pistelli, R Guillot, A Bringuier, B Porokhov, P J Guillausseau, G Feldmann, S Zivanic, M Cizmic, R Dragojevic, M Vanovic, L B Borghouts, G P J van Kranenburg, G Schaart, H A Keizer, A M Niess, H H Dickuth, O Lutz, P Barbe, C Calazel-Fournier, G Hernandez, F Saint-Martin, J Galitzky, A A Gonçalves, E C da Silva, I J L Brito, C A da Silva, N J Lawrence, E Kousta, H Mulnier, A Penny, B Millauer, D G Johnston, S Robinson, G Perriello, W Pimenta, S Pampanelli, P Lucidi, M Lepore, F Porcellati, M C Cordoni, P De Feo, G B Bolli, M Sjöstrand, A Holmäng, P Lönnroth, B Hauer, P Grauer, S Artzner, R Lang, M Stumvoll, L D Monti, P M Piatti, F Gemone, G Valsecchi, M Magni, E Barbieri, E Setola, E P Sandoli, M Galli-Kienle, A E Pontiroli, Gregory A Nichols, Jonathan B Brown, E Salzsieder, H Boltz, J C Ramirez, A Rutscher, U Fischer, Ch Koenig, M Friske, W Schramm, R Landgraf, W Bachmann, M Bangemann, G Groeneveld, Anders Edvell, Per Lindström, P Tsiotra, A Koukourava, S A Raptis, C Tsigos, E Boutou, A Triandaffilopoulou, E M Egido, J Rodríguez-Gallardo, E Gutiérrez, P García, R A Silvestre, J Marco, Akhtar Khan, Zong-Chao Ling, Bo Ahren, Suad Efendic, C Bünting, X Du, G Zhi Sui, P Rösen, T Koschinsky, T M Kearney, P S Sharp, A Lapolla, D Fedele, L Martano, M Garbeglio, R Seraglia, D Favretto, P Traldi, R Meerwaldt, A J Smit, Th P Links, A M V Roon, R Graaf, R O B Gans, O Deynelİ, H Ö Ersöz, D Gogas, A S Fak, S Akalin, M Veglio, R Sivieri, A Chinaglia, L 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Kendall, R Schiaffini, A Pantaleo, T Battocletti, V Vaccari, C Brufani, E Martuscelli, P Gargiulo, E Nieszner, I Posa, E Kocsis, I Préda, G Pogatsa, M Z S Koltai, A Stefanidis, S Manoussakis, S Handanis, M Zairis, D Vitalis, L Dadiotis, P Fiorina, E La Rocca, E Astorri, C Rossetti, G Lucignani, D Giudici, R Castoldi, N Mazarakis, E Giagiakou, A Karavidas, A Agellou, O Karamani, E Matsakas, F Caviezel, L Morricone, M Ranucci, S Denti, A Cazzaniga, R Enrini, G Isgrò, F J González de Molina, J Sala, R Masià, J Marrugat, P Kruszewski, B Wolnik, L Bieniaszewski, E Świerblewska, E Semetkowska-Jurkiewicz, B Krupa-Wojciechowska, P G Vasilikos, A E G Alaveras, N G Anastasopoulos, E Chala, M Sidira, P D Christakopoulos, P L Poulsen, K W Hansen, E Ebbehøj, S T Knudsen, C E Mogensen, Y Ramu, Y Vidyullatha, K Strojek, J Gorska, E Morawin, E Ritz, A Ciavarella, P L Malini, E Strocchi, N Fiumi, E Ambrosioni, B Idzior-Waluś, L Stevens, J McEneny, M J O'Kane, K W Moles, C McMaster, I S Young, W Leonhardt, E Konstadelou, Alper Gürlek, S Soedamah-Muthu, M R Taskinen, C Ehnholm, A Wägner, Laia Bayen, M Rigla, E Ortega, A Caixàs, A Mestrón, J Ordóñez, A Pérez, G Sotiropoulou, P L Servais, A Bertolotto, M Pilo, G Suchánková, S Andratschke, M Tschöp, C-J Strasburger, L Rizzo, P Aerts, M Vinckx, J C Ansquer, M Ryan, H Buter, G J Navis, P E de Jong, D de Zeeuw, G Carreras, G Giménez, J M Pou, K Howorka, M Gabriel, J Pumprla, A Köves, N B Bhowmik, A Haque, A Rahman, F Paleari, P Gamba, G Mauri, G Rovaris, C Giannattasio, M L Piatti, A Zincone, G Cavaletti, G Mancia, S Lan, J Arezzo, R A Gerber, S S Klioze, C Saponara, T Tartaglione, S Cercone, S Caputo, T Meloni, D Brunetti, V Di Lazzaro, G Xu, H Y Jiang, M E Shy, K Sugimoto, W-X Zhang, T Kuchmerovskaya, G Donchenko, I Shymansky, N Kuchmerovsky, L Pakyrbaeva, N E Cameron, A Keegan, M A Cotter, D Mirrlees, S E Smale, G J Biessels, S E J Duis, A Kamal, W H Gispen, A Carrington, S Carman, H Smiarowski, D Lavoie, D Sawicki, A Sabetta, J Litchfield, M Van Zandt, J Sredy, V Smirnova, I Strokov, L Ivanova, A Ichunina, J Nakamura, M Nakayama, Y Hamada, S Chaya, K Kato, Y Kasuya, R Mizubayashi, K Miwa, Y Yasuda, H Kamiya, N Hotta, K Bíró, T Kukorelli, N Szilágyi, M Kürthy, A Komáromy, T Mogyorosi, K Nagy, M Çakir, N Baskal, S Güllü, A H Elhan, G Erdogan, D Ziegler, R Piolot, J Neubauer, B Senesi, R Bonetti, A Napolitano, F Canepa, P Ottonello, A Schabmann, G Giménez-Pérez, J A Arroyo, T López, E Ponz, D Mauricio, P Diem, L Zanchin, S L Suter, J D Lefrandt, A Smit, A M van Roon, R Dullaart, D Voita, V Mackevics, A Vitols, Cs Lengyel, Gy Farkas, T Török, P Légrády, T T Várkonyi, A Kardos, Z Gingl, P Kempler, L Rudas, J Lonovics, M Marchand, L K Stevens, Gy Tarnás, F Estrella, N J Christensen, K Keresztes, I Barna, Zs Hermányi, P Vargha, L Bonnevie, X Chanudet, P Larroque, N Bascil Tutuncu, A Deger, M K Batur, A Yildirir, O Onalan, S Aksöyek, G Kabakçι, T Erbaş, D Galicka-Latała, A Surdacki, J Gerritsen, B J TenVoorde, R M Heethaar, T S Tagawa, M Kodama, R Yoshioka, Y Yamasaki, T Didangelos, V Athyros, A Kontopoulos, A Papageorgiou, D Karamitsos, S Lacigová, Z Rušavý, R Kárová, H Perrild, L Kay, T Jørgensen, A I Bień, P Witek, Elizabete Geraldes, D Rodrigues, L Pereira, A Doménech, P Leitão, D Anagnostopoulos, A V M Foster, S Nag, M Barsoum, G Lewis, N Dunlop, V Connolly, R Bilous, W Kelly, E Chantelau, A Gede, D Sharman, D O'Halloran, C Best, Z G Abbas, J Lutale, G V Gill, W R Jarvis, L K Archibald, S Corcoran, J Mansell, L Pibworth, H Terada, T Shiba, N Utugi, T Utugi, M Blum, J Strobel, K Höffken, F M Razvi, E E Kritzinger, K Taylor, S Jones, W Illahi, M Grüβer, P Hartmann, K Hoffstadt, H A van Leiden, A C Moll, B C P Polak, G B Pietragalla, M Maurino, M Montanaro, Ş Karadeniz, P Tommasini, C Quadrini, V Demiraj, E Rispoli, A Ota, H Takama, N Saito, C Hemández, D Lepore, L Antico, B Giardina, F Franconi, E Michoud, S Chamot, Ch Riva, H-P Hammes, O Renner, G Breier, J Lin, A Alt, C Betzholtz, R G Bretzel, R Manti, M Gallo, A Molinar Hin, E Brignardello, G Boccuzzi, Shanfang Li, Kunsan Xiang, Rugeng Zhang, Xinhong Shangguan, Jianrong Wu, P T Donnan, J Broomhall, K Hunter, A D Morris, G Ioannidis, M Peppa, E Rontogianni, M Kallifronas, I Lekatsas, G Chrysanthopoulou, L Anthopoulos, M Kesse, N Thalassinos, C Neves, J L Medina, F Lopes, M Yılmaz, N Güvener, M Güvener, T Kocagöz, E Böke, I Paşaoglu, N Bascil Tutuncu, A Oto, M K Karvonen, M Koulu, U Pesonen, M Mercuri, R Rauramaa, M K Rutter, P Kestevan, J M McComb, S M Marshall, M Sobieska, K Wiktorowicz, S D J M Kanters, J D Banga, A Algra, C J M Frijns, J J Beutler, R Fijnheer, G Nicoloff, S Baydanoff, N Stanimirova, Ch Petrova, S Lario, J M Campistol, A Cases, J Clària, P Iñigo, E Esmatjcs, B Sármán, M Tóth, I Kocsis, A Somogyi, A Bumbure, K Jachimowicz, J Samson, M Tomasiak, A Sobol, L Stańczyk, C Watala, P Stradina, M Wiśniewska-Jarosińska, D Marciniak, B Więcławska, C Watała, J Golański, R Zinnat, I Mahmud, Yahya Büyükasik, H Demiroğlu, A Szczepanik, M Skowroński, A Murawska, D R Meeking, S Allard, J Munday, P Chowienczyk, K M Shaw, M H Cummings, R Šimková, M Jirsa, P W F Hadoke, C A McIntyre, G C Jones, B C Williams, A I Elliott, J A McKnight, J Pernow, G C Bombonato, G F Finucci, L Zotta, V Senses, S Ozyazgan, E Ince, M Tunçdemir, M Oztürk, G Sultuybek, A G Akkan, S Özyazgan, Y Unlücerci, S Bekpınar, M F Meyer, B C Lee, A C Shore, J M Humphreys, J E Tooke, G Dell'Omo, G Giovannitti, F Caricato, M Mariani, R Pedrinelli, C Kiviet-Boehm, V Schwelling, S Matthäei, M Pfohl, D McInerney, H Itoh, T Ohno, N Katoh, S Baumgartner-Parzer, M Artwohl, W Graier, C Ludwig, Y Tachi, C Bannai, M Shinohara, H Shimpuku, K Ohura, A Bertacca, M Sasvári, E Szaleczki, P Pusztai, U Boes, E Klaus, P Dittrich, Z Wagner, I Wittmann, L Pótó, L Wagner, I Mazák, J Nagy, F Feletto, C Taboga, L Tonutti, S Lizzio, A Russo, V Selmo, A Ceriello, J Lekakis, C M Papamichael, K Stamatelopoulos, S Stamatelopoulos, D O Yillar, M Gay, E Lillaz, A Passaro, A Vanini, F Calzoni, K D'Elia, M Carantoni, G Zuliani, R Fellin, A Solini, G Chwatko, E Bald, A-S Dramais, P E Wallemacq, B Vandeleene, M V Ciaria, M Ariano, R Strom, J Gibney, U Weiss, B Turner, P O'Gorman, G Watts, J Powrie, M Crook, K Shaw, M Cummings
No abstract text is available yet for this article.
August 1999: Diabetologia
Figen Taser, Ayse Nur Deger, Hakkı Deger
AIM: To investigate and compare the histological findings of patients with diabetes, hypothyroidism and idiopathic carpal tunnel syndrome (CTS). MATERIAL AND METHODS: Subsynovial connective tissue samples of 51 idiopathic CTS patients (Group 1), 58 diabetic CTS patients (Group 2) and 16 hypothyroid CTS patients (Group 3) were evaluated in this study. The histopathological examination parameters were; number of fibroblasts, size of collagen fibers, vascular changes (vascular proliferation, intimal thickening and changes of vessel structures), edema and inflammatory infiltration...
2017: Turkish Neurosurgery
Turgay Arinsoy, Serpil Muge Deger, Kenan Ates, Bulent Altun, Tevfik Ecder, Taner Camsari, Kamil Serdengecti, Gultekin Suleymanlar
BACKGROUND: Obesity confers an increased risk of chronic kidney disease (CKD), which is increased further by accompanying metabolic abnormalities. OBJECTIVE: To investigate the relationship of the risk of CKD with obesity and metabolic syndrome (MS) in adults by means of post hoc analysis of data from the Chronic Renal Disease in Turkey (CREDIT) study. METHODS: The anthropometric measurements of a total of 9,100 adult participants in the CREDIT study were included in the analyses...
November 2016: Journal of Renal Nutrition
Yalçın Sönmez, Zülfü Bayhan, Faik Yaylak, Mehmet Fatih Ekici, Ayşe Nur Değer
Appendiceal malignancies are rare clinic entities. The clinical presentation of appendiceal malignancies is often atypical. Acute abdominal pain and acute appendicitis, which requires early surgical intervention, are the most common clinical presentations of appendiceal malignancies. In this case report, an adenocarcinoma of the appendix in a 64-year-old male from a nursing home has been presented. He had right lower quadrant pain for the last 5 days. On physical examination, he had significant guarding. Intravenous contrast-enhanced abdominopelvic tomography revealed no pathological features...
2016: Ulusal Cerrahi Dergisi
Bestami Ciftci, Nesibe Uzel, M Onur Ozel, Sema Zergeroglu, Cetin Deger, S Sare Turasan, Ayse Gul Karakoc, Semra Ozbalci
AIM: This study aims to assess the educational needs of family practitioners and evaluate the efficacy of the ongoing "Maternal Health and Family Planning Distance Education" program conducted by the General Directorate of Health Research (SAGEM) of the Turkish Ministry of Health. METHODS: This study consisted of three phases. In the first phase, an online survey on maternal health and family planning educational needs was sent to 20,611 physicians via e-mail. Of the 20,611 physicians, 4,729 completed the survey...
2016: Advances in Medical Education and Practice
Serpil Muge Deger, Adriana M Hung, Charles D Ellis, Cindy Booker, Aihua Bian, Guanhua Chen, Naji N Abumrad, T Alp Ikizler
BACKGROUND AND OBJECTIVES: Protein energy wasting and systemic inflammation are prevalent in maintenance hemodialysis (MHD) patients. Omega-3 (ω-3) fatty acids have anti-inflammatory properties and have been shown to improve protein homeostasis. We hypothesized that administration of high-dose (2.9 g/d) ω-3 would be associated with decreased muscle protein breakdown in MHD patients with systemic inflammation. DESIGN, SETTING, PARTICIPANTS & MEASUREMENTS: This is a substudy from a randomized, placebo-controlled study (NCT00655525)...
July 7, 2016: Clinical Journal of the American Society of Nephrology: CJASN
İnanç Değer Fidancı, Tufan Aydoğdu, Hande Çağlayan
Hemophilia A is an X-linked bleeding disorder resulting mostly from heterogeneous point mutations in the factor VIII (F8) gene. Small/large gene deletions, insertions and gross gene rearrangements underlie the molecular pathogenesis of the disease. Two large inversion mutations due to intrachromosomal recombinations between inverted repeats found in intronic sequences and upstream regions of the F8 gene result in severe hemophilia A. The intron 1 inversion mutation is responsible for about 2% of the cases in various populations...
March 5, 2006: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
Kamuran Cumhur Değer, Ebubekir Gündeş, Ali Fedakar
Aneurisms of the splenic artery are rare clinical findings. Surgeons and interventional radiologists should co-operate in the management of this challenging disease; we describe here a surgical option.
May 2016: Clinical Case Reports
Chiu-Ju Lin, Kristen A Deger, Joseph H Tien
Symptom severity affects disease transmission both by impacting contact rates, as well as by influencing the probability of transmission given contact. This involves a trade-off between these two factors, as increased symptom severity will tend to decrease contact rates, but increase the probability of transmission given contact (as pathogen shedding rates increase with symptom severity). This paper explores this trade-off between contact and transmission given contact, using a simple compartmental susceptible-infected-recovered type model...
July 2016: Mathematical Biosciences
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