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https://read.qxmd.com/read/38313803/primary-central-nervous-system-post-transplant-lymphoproliferative-disorder-after-allogeneic-stem-cell-transplantation-a-case-report
#1
Margaret Tugend, Jordan Dattero, Tsiporah Shore, Vladislav Korobeynikov, Raymond F Sekula
PURPOSE: Primary central nervous system, diffuse large B-cell lymphoma, post-transplant lymphoproliferative disorder in the cerebellopontine angle after an allogeneic stem cell transplantation has never been reported in the literature. Typically, diffuse large B-cell lymphoma is non-polyploid. We report the first case of a patient with polyploid post-transplant lymphoproliferative disorder in the cerebellopontine angle who presented with back pain. CASE PRESENTATION: A 45-year-old man with a history of nodular sclerosing classic Hodgkin lymphoma stage IIB treated with systemic chemotherapy, external radiation and autologous stem cell transplant and double umbilical cord allogeneic transplant presented with several weeks of back pain...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38249266/non-hodgkin-lymphoma-mimicking-vestibular-schwannoma
#2
Marco Antônio S Vaz, Rafaela F Gonçalves, Joel Lavinsky, Gustavo Rassier Isolan
Progressive unilateral hearing loss and an MRI are usually enough to diagnose vestibular schwannoma (VS). We were consulted by a 45-year-old man with otalgia and left-sided hearing loss as well as ipsilateral facial paralysis that had begun two weeks prior. Due to a possible atypical presentation of VS, an MRI was ordered, which revealed an intracanalicular lesion occupying the left cerebellopontine angle cistern. With no signs of systemic disease and considering the total left ear deafness, the patient underwent retrolabyrinthine mastoidectomy...
December 2023: Curēus
https://read.qxmd.com/read/37636538/primary-large-b-cell-lymphoma-involving-the-cerebellopontine-angle-mimic-acoustic-schwannoma-role-of-mr-spectroscopy-in-differential-diagnosis-a-case-report
#3
Pier Paolo Arcuri, Vincenzo Aiello, Simonetta Antonelli, Giuseppe Lucio Cascini, Marco Rossi, Domenico Laganà
Primary central nervous system (CNS) lymphoma is a very rare aggressive non-Hodgkin disease that originates in CNS (brain, leptomeninges, spinal cord, or eyes). It seems to have increased over the last two decades in both immunocompromised and immunocompetent patients. Primary large B-cell lymphoma involving the cerebellopontine angle (CPA) is extremely rare: only 15 cases of large B-cell lymphoma of the CPA have been reported worldwide; based on our knowledge, no cases studied with MR Spectroscopy. Primary large B-cell lymphoma of the CPA must be differentiated from other cerebellopontine angle diseases, such as acoustic neuroma and meningioma...
October 2023: Radiology Case Reports
https://read.qxmd.com/read/34341695/primary-dural-lymphoma-mimicking-en-plaque-cerebellopontine-angle-meningioma
#4
Mei Xu, Ashish Bains, Yuan Rong
Primary dural lymphoma (PDL) usually arises from the calvarial dura without the brain parenchyma or systemic involvement and thus may not be considered as a typical form of primary CNS lymphoma (PCNSL). It is exceedingly rare. When it occurs, it might not be suspected as a primary diagnosis on clinical and radiologic findings. We present a PDL case that occurs at the cerebellopontine (CP) angle mimicking en plaque meningioma. The tumor histopathology showed a lymphoproliferative disorder immunophenotypically consistent with a low-grade marginal zone lymphoma...
2021: Case Reports in Pathology
https://read.qxmd.com/read/33165439/primary-large-b-cell-lymphoma-involving-the-cerebellopontine-angle-a-case-report
#5
Yazhou Lin, Minjie Huang, Fang Wang, Dingkang Xu, Qiang Gao, Weidong Zang, Fuyou Guo, Zhihua Li
Primary large B-cell lymphomas involving the cerebellopontine angle (CPA) are uncommon. Fewer than 20 cases of large B-cell lymphoma at the CPA have been reported worldwide. Herein, we report a rare case of B-cell lymphoma in a 67-year-old woman who presented with dysphagia and dizziness and showed a lesion involving the right CPA on magnetic resonance imaging (MRI). The primary diagnosis was metastatic tumor; however, postoperative pathology confirmed a diffuse large B-cell lymphoma. The initial symptoms were resolved completely at the 2-month postoperative follow-up, and the postoperative course was uneventful...
2020: International Journal of Clinical and Experimental Pathology
https://read.qxmd.com/read/31723484/primary-central-nervous-system-lymphoma-with-peripheral-nerve-involvement-case-report
#6
Yoshimasa Mori, Koh Yamamoto, Ako Ohno, Masaharu Fukunaga, Atsushi Nishikawa
A 50-year-old man presented with dizziness and hearing disturbance in the right ear. Magnetic resonance imaging (MRI) revealed a well-enhanced mass lesion in the right cerebellopontine (CP) angle that appeared to originate in the cerebellum. A surgical specimen obtained at the subtotal resection with craniotomy revealed a diffuse large B-cell lymphoma (DLBCL). During the three courses of chemotherapy with high-dose methotrexate (MTX) with leucovorin rescue, he developed a right abducens palsy, left oculomotor palsy, left facial palsy, right trigeminal sensory disturbance, and paraparesis...
September 16, 2019: Curēus
https://read.qxmd.com/read/29656000/primary-central-nervous-system-lymphoma-at-the-cerebellopontine-angle-mimicking-a-trigeminal-schwannoma-a-unique-case-report-and-literature-review
#7
REVIEW
Vijay Seevaratnam, Yingda Li, Sun Loong Keegan Lee, Gemma Olsson
Primary central nervous system lymphoma (PCNSL) is an uncommon extranodal manifestation of non-Hodgkin's lymphoma with those presenting at the cerebellopontine angle (CPA) being rare presentations with limited reported cases in the literature. We report a 60-year old female presenting with PCNSL of the left CPA radiologically mimicking a trigeminal schwannoma with corresponding clinical signs. Imaging showed a left CPA lesion that was biopsied and confirmed as diffuse large B-cell lymphoma. Given its rarity, PCNSL should be considered in the differential diagnosis for all CPA tumours...
June 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://read.qxmd.com/read/29040677/navigation-linked-heads-up-display-in-intracranial-surgery-early-experience
#8
JOURNAL ARTICLE
Justin R Mascitelli, Leslie Schlachter, Alexander G Chartrain, Holly Oemke, Jeffrey Gilligan, Anthony B Costa, Raj K Shrivastava, Joshua B Bederson
BACKGROUND: The use of intraoperative navigation during microscope cases can be limited when attention needs to be divided between the operative field and the navigation screens. Heads-up display (HUD), also referred to as augmented reality, permits visualization of navigation information during surgery workflow. OBJECTIVE: To detail our initial experience with HUD. METHODS: We retrospectively reviewed patients who underwent HUD-assisted surgery from April 2016 through April 2017...
August 1, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://read.qxmd.com/read/28663949/primary-central-nervous-system-lymphoma-of-the-cerebellopontine-angle-that-initially-occurred-as-neurolymphomatosis-of-the-acoustic-nerve
#9
JOURNAL ARTICLE
Sadaharu Tabuchi, Hiroki Yoshioka, Hiroyuki Nakayasu, Takashi Watanabe
We report a rare case of a primary central nervous system lymphoma (PCNSL) of the cerebellopontine angle (CPA) with infiltration into the pyramidal tract that initially presented as neurolymphomatosis (NL) of the acoustic nerve. A 60-year-old male suffered from right-side deafness and was referred to an otolaryngologist. Magnetic resonance imaging (MRI) showed fusiform enlargement of the right acoustic nerve with a hyperintense signal on a T2-weighted image (T2WI) and with gadolinium (Gd) enhancement, without an evidence of parenchymal CNS involvement...
October 2014: NMC Case Report Journal
https://read.qxmd.com/read/27559959/an-uncommon-case-of-lymphoplasmacytic-lymphoma-in-cerebellopontine-angle-region-case-report-with-a-literature-review
#10
REVIEW
Chengrui Yan, Xiangyi Kong, Lanshu Yang, Wenbin Ma
In the central nervous system, cerebellopontine angle (CPA) lymphomas are rare; few cases have been reported. Lymphoplasmacytic lymphoma (LPL) in the CPA is rarer still, and often misdiagnosed as acoustic neuroma.We report a rare case of CPA LPL-a challenging diagnosis guided by clinical presentations, radiological signs, and postoperative pathological test.A 43-year-old woman presented with headaches. Her magnetic resonance imaging revealed an abnormal homogeneously enhancing mass in the left CPA. We present detailed analysis of her disease and review relevant literature...
August 2016: Medicine (Baltimore)
https://read.qxmd.com/read/25750225/t-cell-primary-leptomeningeal-lymphoma-in-cerebellopontine-angle
#11
JOURNAL ARTICLE
Laisa Socorro Briongos-Figuero, Tamara Gómez-Traveso, José Luis Pérez-Castrillon
Primary meningeal lymphomas are very rare and those derived from T cells are even more infrequent (less than 5% of primary central nervous system lymphomas). Cerebellopontine angle involvement in the primary T-cell lymphoma is exceptional. Clinical presentation depends on the type of lesions, and histological diagnosis is needed. We present a rare case of a 50-year-old woman who presented with clinical cerebellar syndrome with posterior opsoclonus-myoclonus syndrome. Necropsy evaluation revealed primary diffuse leptomeningeal non-Hodgkin's T-cell lymphoma...
March 6, 2015: BMJ Case Reports
https://read.qxmd.com/read/25226376/cerebellopontine-angle-and-intracanalicular-masses-mimicking-vestibular-schwannomas
#12
JOURNAL ARTICLE
Audrey P Calzada, John L Go, Donald L Tschirhart, Derald E Brackmann, Marc S Schwartz
OBJECTIVE: To describe the clinical and radiographic characteristics in a series of patients with non-vestibular schwannoma cerebellopontine angle (CPA) and intracanalicular (IAC) masses, who underwent microsurgery for presumed vestibular schwannoma (VS). STUDY DESIGN: Retrospective case series. SETTING: Tertiary neurotologic referral center. PATIENTS: One thousand five hundred ninety-three patients underwent microsurgery for apparent VS from 2002 to 2013...
March 2015: Otology & Neurotology
https://read.qxmd.com/read/24950551/non-hodgkins-lymphoma-presenting-as-garcin-s-syndrome
#13
JOURNAL ARTICLE
D Hammond, K Rehman, N Grew
An 80 year old man presented with a twelve month history of progressive multiple unilateral cranial nerve palsies. A gadolinium enhanced MRI scan of his head and neck was performed. This showed an extra-axial enhancing lesion, which enveloped the hemi-mandible at the level of the left inferior alveolar nerve, and a dumbbell shaped lesion within the cerebellopontine angle. An incisional biopsy was performed to gain a tissue diagnosis, which demonstrated a Non-Hodgkin's Lymphoma. The combination of signs, symptoms and radiological findings enabled a diagnosis of Garcin's Syndrome secondary to Non-Hodgkin's Lymphoma...
October 1, 2011: Journal of Surgical Case Reports
https://read.qxmd.com/read/24232070/cerebellopontine-angle-lymphoma
#14
JOURNAL ARTICLE
Jennifer H Ta, Helen Xu
No abstract text is available yet for this article.
December 2013: Otology & Neurotology
https://read.qxmd.com/read/22522336/radiation-induced-world-health-organization-grade-ii-meningiomas-in-young-patients-following-prophylactic-cranial-irradiation-for-acute-lymphoblastic-leukemia-in-childhood-three-case-reports
#15
JOURNAL ARTICLE
Keiko Oda, Taku Sato, Tadashi Watanabe, Masahiro Ichikawa, Eiji Ito, Yuka Matsumoto, Hitoshi Ando, Jun Sakuma, Atsushi Kikuta, Hiroshi Hojo, Kiyoshi Saito
Current chemotherapeutic regimens have been used to successfully treat many children with acute lymphoblastic leukemia (ALL), but have resulted in an increased risk of late central nervous system tumors, most commonly meningioma, particularly in patients who have received cranial irradiation. We treated 3 young patients with World Health Organization grade II meningiomas who had previously received cranial irradiation for the treatment of childhood ALL: a cerebellopontine angle tumor in a 19-year-old woman, a petroclival tumor in a 28-year-old man, and a frontal parasagittal tumor in a 19-year-old woman...
2012: Neurologia Medico-chirurgica
https://read.qxmd.com/read/22360042/b-cell-lymphoma-of-the-brainstem-with-central-neurogenic-hyperventilation
#16
JOURNAL ARTICLE
Syed Ather Enam, Rushna Ali
Non-Hodgkin's lymphoma of the brainstem is a rare entity. Central Neurogenic Hyperventilation (CNH), an associated manifestation of this disease, is an even rarer event. We report a case of an immunocompetent individual who presented to us with tachypnea and facial nerve palsy. Neuroimaging showed a Cerebellopontine angle tumour which on histopathology showed feature consistent with a Non-Hodgkin's B-Cell Lymphoma. The patient went on to develop severe respiratory alkalosis with findings consistent with CNH...
September 2011: JPMA. the Journal of the Pakistan Medical Association
https://read.qxmd.com/read/22218708/atypical-teratoid-rhabdoid-tumor-located-in-the-pineal-region-following-prophylactic-irradiation-for-acute-lymphoblastic-leukemia
#17
JOURNAL ARTICLE
Atsushi Kuge, Shinya Sato, Kaori Sakurada, Sunao Takemura, Takamasa Kayama
Atypical teratoid rhabdoid tumor (AT/RT) is a rare entity. In the central nervous system, AT/RT generally arises from the posterior fossa of infants and behaves aggressively. AT/RT is reported to arise from the infratentorial region (63%) and other sites, such as the suprasellar region, cerebellopontine angle, and spinal cord. The pineal region is rare (6%) as a site of origin. Radiation-induced brain tumors are well known. In this report, we present a case of a pineal region tumor causing acute hydrocephalus that could be pathologically diagnosed as AT/RT following prophylactic cranial irradiation for acute lymphoblastic leukemia...
July 2012: Brain Tumor Pathology
https://read.qxmd.com/read/21210165/case-series-non-vascular-considerations-in-trigeminal-neuralgia
#18
JOURNAL ARTICLE
Sathesh Balasundram, Stefano Cotrufo, Colin Liew
An abnormal vascular course of the superior cerebellar artery is often cited as the cause for trigeminal neuralgia. However, among patients with TN-like symptoms, 6% to 16% are variously reported to have intracranial tumours. Aneurysms, tumours, or other lesions may impinge or irritate the trigeminal nerve along its course. Uncommonly, an area of demyelination from multiple sclerosis may be the precipitant. We would like to present a series of unusual lesions, all of which initially presented with neuralgic-like symptoms and were refractory to treatment...
February 2012: Clinical Oral Investigations
https://read.qxmd.com/read/19770549/challenges-in-neurosurgical-intraoperative-consultation
#19
JOURNAL ARTICLE
Shalinee Rao, Aarthi Rajkumar, M D Ehtesham, Prathiba Duvuru
BACKGROUND: Intraoperative consultation for neurosurgical specimens can be difficult at times, despite the use of both frozen section and squash preparation. Various factors influence the diagnostic accuracy of these procedures. This study was conducted to evaluate reasons for discordant case results in neurosurgical intraoperative consultations and make a comparative analysis of these two commonly used methods to identify the possible pitfalls, errors, and limitations. MATERIALS AND METHODS: All the neurosurgical cases received in the Department of Pathology for intraoperative consultation over a period of 3 years were studied retrospectively...
July 2009: Neurology India
https://read.qxmd.com/read/18066510/-primary-b-cell-non-hodgkin-lymphoma-of-the-internal-auditory-canal-case-report-and-literature-review
#20
REVIEW
F B Knapp, E Rieh, J Spreer, T Klenzner, W Maier
A primary non-Hodgkin lymphoma (NHL) of the internal auditory canal or the cerebellopontine angle is an absolute rarity, even among the unusual lesions encountered there. Schwannomas or meningiomas account for approximately 90-95% of the tumors of the cerebellopontine angle and the internal auditory canal. Atypical symptoms, such as facial nerve palsy or rapid progression, require differential diagnostics to identify less frequent entities. However, clinical symptoms or the image morphology cannot confirm the diagnosis of a lymphoma...
June 2008: HNO
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