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Tessa Kerkman, Lea M Dijksman, Melanie A M Baas, Ruth Evers, Maria G van Pampus, Claire A I Stramrood
INTRODUCTION: Traumatic events that occur in a clinical setting can have long-lasting adverse effects on persons who are affected, including health care providers. This study investigated the prevalence of work-related traumatic events, posttraumatic stress disorder (PTSD), anxiety, and depression among Dutch midwives. Additionally, differences between midwives working in primary care (independently assisting births at home and in birthing centers) and midwives working in secondary or tertiary care (hospital setting) were examined...
March 19, 2019: Journal of Midwifery & Women's Health
Diarmid Jm Sinclair, Sai Zhao, Fang Qi, Kazare Nyakyoma, Joey Sw Kwong, Clive E Adams
BACKGROUND: Electroconvulsive therapy (ECT) involves the induction of a seizure by the administration of an electrical stimulus via electrodes usually placed bilaterally on the scalp and was introduced as a treatment for schizophrenia in 1938. However, ECT is a controversial treatment with concerns about long-term side effects such a memory loss. Therefore, it is important to determine its clinical efficacy and safety for people with schizophrenia who are not responding to their treatment...
March 19, 2019: Cochrane Database of Systematic Reviews
R Midani, C H Splieth, M Mustafa Ali, J Schmoeckel, M S Mourad, R M Santamaria
BACKGROUND: The Hall Technique is a less invasive caries management technique for treating carious primary molars. It has become a routine treatment at specialists' practices. AIM: To retrospectively evaluate the clinical success and survival rates of preformed metal crowns placed on primary molars using the Hall Technique in a Paediatric Dentistry Setting. DESIGN: Patient records of children receiving Hall crowns (with or without proximal slicing) between 2011 and 2017 were reviewed...
March 19, 2019: International Journal of Paediatric Dentistry
Anna Wintersand, Klara Asplund, Jonas Binnmyr, Erik Holmgren, Ola B Nilsson, Guro Gafvelin, Hans Grönlund
BACKGROUND: Five to ten percent of the population in affluent countries are allergic to dog. Diagnosis and treatment is based on allergen extracts from natural sources where composition and concentration are poorly defined. OBJECTIVE: We aimed to quantify six dog allergens (Can f 1-6) in commercial skin prick test (SPT) solutions and to determine individual allergen profiles in dogs. METHOD: The allergen content of SPT solutions from five vendors and allergen source material from three anatomical sites were analyzed...
March 19, 2019: Allergy
Marcel Grube, Felix Neis, Sara Y Brucker, Stefan Kommoss, Jürgen Andress, Martin Weiss, Sascha Hoffmann, Florin-Andrei Taran, Bernhard Krämer
Fibroids are the most common benign tumors in women of childbearing age and can be found in almost 80-90% of all women by age 50 years. They can cause pain, excessive menstrual bleeding or infertility. The development of fibroids increases with age. Since the age of women in industrial countries who are trying to conceive is generally increasing, there has been a growing demand for minimally invasive and uterine-sparing surgical treatment of fibroids. Whereas the main focus of previous surgical techniques for the treatment of fibroids was enucleation of the tumour with subsequent closure of the uterine incision, modern devices developed over the past decade can destroy fibroids by using ultrasound or radio-frequency without incising the uterine wall...
March 18, 2019: Surgical Technology International
Nipun Sodhi, Anton Khlopas, Joseph O Ehiorobo, Caitlin Condrey, Kevin Marchand, Robert C Marchand, Matthew S Hepinstall, Michael A Mont
INTRODUCTION: Tibial or femoral extra-articular deformities complicate the goal achieving optimal mechanical axis alignment for successful total knee arthroplasty (TKA) outcomes. In the presence of these extra-articular deformities, standard operative techniques and instruments may not be reliable. Robotic-arm assisted technology was developed to help achieve a well-aligned and balanced knee in a variety of clinical scenarios. Although prior case series have reported on the use of robotic-arm assisted devices for cases with severe angular deformity, there is a lack of data concerning the use of the robotic device for patients with other potentially complex surgical factors...
March 18, 2019: Surgical Technology International
Seema Alam, Bikrant Bihari Lal, Vikrant Sood, Rajeev Khanna, Guresh Kumar
BACKGROUND AND AIMS: Doubts have been raised about efficacy of New Wilson's index (NWI) in predicting Liver Transplant (LT) or mortality in decompensated Wilson Disease (WD) patients. APASL ACLF Research Consortium (AARC) has introduced a new score (AARC-ACLF) which has not been studied in children. METHODS: Data of all pediatric WD cases were prospectively collected and analyzed. Cox regression and Area Under Receiver Operative Curve (AUROC) analyses were used to identify best predictive score for mortality at 90 days...
March 19, 2019: Hepatology International
Ryota Wakayama, Susumu Uchiyama, Damien Hall
One important aspect of the green chemistry revolution has been the use of ionic liquids as the solvent in liquid-phase enzymatic catalysis. An essential requirement for protein enzyme function is the correct folding of the polypeptide chain into its functional "native" state. Quantitative assessment of protein structure may be carried out either empirically, or by using model-based characterization procedures, in which the parameters are defined in terms of a standard reference state. In this short note, we briefly outline the nature of the parameters associated with different empirical and model-based characterization procedures and point out factors which affect their interpretation when using a base solvent different from water...
March 19, 2019: Biophysical Reviews
Jin-Li Wei, Yi-Zhou Jiang, Zhi-Min Shao
BACKGROUND: With the improvement in the survival of breast cancer, developing second primary malignancy becomes a serious health issue. The aim of this study was to explore the survival of breast cancer patients with second primary malignancy, and to evaluate the impact of chemotherapy on the risk of different cancer sites. METHOD: Obtaining data from the Surveillance, Epidemiology, and End Results database, we calculated the standardized incidence ratio (SIR) for second primary malignancy in breast cancer survivors between 2000 and 2014...
March 19, 2019: International Journal of Clinical Oncology
Shiqing Luo, Yanming Miao, Junping Guo, Xiaojie Sun, Guiqin Yan
Mesoporous molecularly imprinted polymers (MIPs) containing mangnanese-doped ZnS quantum dots (Mn-ZnS QDs) were prepared for specific recognition and detection of 4-nitrophenol (4-NP). The Mn-ZnS QDs display orange room-temperature phosphorescence with excitation/emission peaks at 295/590 nm and a decay time of 2.0 ms. In the presence of 4-NP, the orange phosphorescence is strongly reduced. Phosphorescence drops linearly in the 0.1-100 μM 4-NP concentration range, and the detection limit is 60 nM. The detection limit is far lower than the maximally allowed 4-NP concentrations in surface water and drinking water as specified by the U...
March 19, 2019: Mikrochimica Acta
Tadaki Nakahara, Yoshiki Owaki, Tsubasa Shindou, Kiyotaka Nakajima, Masahiro Jinzaki
BACKGROUND: Evidence has shown the clinical usefulness of measuring the metastatic tumor burden of bone for prognostic assessment especially in prostate cancer; quantitative evaluation by dedicated SPECT is difficult due to the lack of attenuation correction (AC) method. We developed a novel method for attenuation correction using bone SPECT emission data (bone SPECT-based segmented attenuation correction; B-SAC) where emission data were virtually segmented into three tissues (i.e., bone, soft tissue, and air)...
March 19, 2019: EJNMMI Research
G Maragatham, Shobana Devi
The combination of big data and deep learning is a world-shattering technology that can make a great impact on any industry if used in a proper way. With the availability of large volume of health care datasets and progressions in deep learning techniques, systems are now well equipped in diagnosing many health problems. Utilizing the intensity of substantial historical information in electronic health record (EHR), we built up, a conventional predictive temporal model utilizing recurrent neural systems (RNN) like LSTM and connected to longitudinal time stepped EHR...
March 19, 2019: Journal of Medical Systems
Daniel S Hill, Denis Kinsella, Andrew D Toms
INTRODUCTION: Our aim was to question the usefulness of a three-phase bone scan in the evaluation of pain in the knee region after TKR. Our hypothesis was that an abnormal investigation had a poor association with the presence of infection or loosening, and did not provide any additional diagnostic information above that already available through other standard investigations. METHODS: A retrospective study over a 24-month period was performed comprising 118 patients investigated with a TPBS...
March 19, 2019: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
Hiroshi Noguchi, Yoichi Kakuta, Masayoshi Okumi, Kazuya Omoto, Yasuhiro Okabe, Hideki Ishida, Masafumi Nakamura, Kazunari Tanabe
BACKGROUND: Although minimally invasive procedures have been established as the standard for a donor nephrectomy, there are many different surgical techniques described in the literature. The aim of this study is to compare the outcomes of kidney transplant procedures using the pure retroperitoneoscopic donor nephrectomy (PRDN) and hand-assisted retroperitoneoscopic donor nephrectomy (HARDN) techniques. METHODS: A retrospective study involving 1508 transplant procedures was conducted; 874 were PRDN procedures; and 634 were HARDN...
March 19, 2019: Surgical Endoscopy
Tejs Ehlers Klug, Malene Hentze, Sten Schytte, Lovisa Farnebo, Oddveig Rikardsen, Eero Sihvo, Jari Räsänen, Antti Mäkitie
PURPOSE: We aimed to obtain information on the number of Nordic centers performing tracheal resections, crico-tracheal resections, and laryngo-tracheal reconstructions, as well as the patient volume and the standard regimens associated with these procedures. METHODS: Consultants at all Departments of Otorhinolaryngology-Head and Neck Surgery (ORL-HNS, n = 22) and Thoracic Surgery (n = 21) in the five Nordic countries were invited (April 2018-January 2019) to participate in an online survey...
March 19, 2019: European Archives of Oto-rhino-laryngology
Rodrigo Canellas, Midhir J Patel, Sheela Agarwal, Dushyant V Sahani
OBJECTIVE: To assess the lesion detection performance of an abbreviated MRI (AMRI-M) protocol consisting of ultrafast SE T2W, DWI, and T1W-HBP at 20 min for colorectal liver metastasis (CRLM) surveillance. METHODS: In this Institutional Review Board (IRB)-approved retrospective study, gadoxetic acid-enhanced MRI scans of 57 patients (43 with pathologically proven CRLMs) were assessed. Two readers independently evaluated two sets of images per patient and commented on the number, location, and size of liver lesions...
March 19, 2019: European Radiology
Lucian Beer, Michael Toepker, Ahmed Ba-Ssalamah, Christian Schestak, Anja Dutschke, Martin Schindl, Alexander Wressnegger, Helmut Ringl, Paul Apfaltrer
OBJECTIVES: The aim of this study was to assess the objective and subjective image characteristics of monoenergetic images (MEI[+]), using a noise-optimized algorithm at different kiloelectron volts (keV) compared to polyenergetic images (PEI), in patients with pancreatic ductal adenocarcinoma (PDAC). METHODS: This retrospective, institutional review board-approved study included 45 patients (18 male, 27 female; mean age 66 years; range, 42-96 years) with PDAC who had undergone a dual-energy CT (DECT) of the abdomen for staging...
March 19, 2019: European Radiology
Chong-Fu Jia, Jie Zhong, Xin-Yi Meng, Xi-Xia Sun, Zhi-Qiang Yang, Yu-Jie Zou, Xiang-Yue Wang, Shuang Pan, Da Yin, Zhao-Qian Wang
OBJECTIVE: To explore the image quality (IQ) and diagnostic value of 70 kVp turbo high-pitch coronary CT angiography (THP-CCTA) using automated tube voltage selection (ATVS) and 30 mL of low-concentration contrast agent. METHODS: Patients who underwent 70 kVp THP-CCTA using ATVS with 30 mL of contrast agent (group A) were prospectively enrolled, and those who underwent conventional CCTA (100/120 kVp, prospective sequential mode with 65-75 mL of contrast agent) (group B) were retrospectively selected for study...
March 19, 2019: European Radiology
Susanne M Eijgenraam, Frans A T Bovendeert, Joost Verschueren, Jasper van Tiel, Yvonne M Bastiaansen-Jenniskens, Marinus A Wesdorp, Kazem Nasserinejad, Duncan E Meuffels, Jamal Guenoun, Stefan Klein, Max Reijman, Edwin H G Oei
PURPOSE: To evaluate in vivo T2 mapping as quantitative, imaging-based biomarker for meniscal degeneration in humans, by studying the correlation between T2 relaxation time and degree of histological degeneration as reference standard. METHODS: In this prospective validation study, 13 menisci from seven patients with radiographic knee osteoarthritis (median age 67 years, three males) were included. Menisci were obtained during total knee replacement surgery. All patients underwent pre-operative magnetic resonance imaging using a 3-T MR scanner which included a T2 mapping pulse sequence with multiple echoes...
March 19, 2019: European Radiology
Vivian Man, Ting Ting Wong, Michael Co, Dacita Suen, Ava Kwong
BACKGROUND: The combined use of radioisotope and blue dye is the gold standard in sentinel lymph node (SLN) localization in early breast cancer. Superparamagnetic iron oxide (SPIO) has recently emerged as a non-inferior new tracer in sentinel lymph node mapping with fewer disadvantages. This study represents the first and the largest cohort of superparamagnetic iron oxide application in Asian population. METHODS: Retrospective analysis of a prospectively maintained database was performed from August 2016 to December 2017...
March 19, 2019: World Journal of Surgery
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