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Anne-Sophie Fiolet, Elise Jandot, Pauline Doucey, Coralie Crétet, Célia Brunel, Christine Pivot, Jean-Marc Ghigo, Christophe Beloin, David Lebeaux, Fabrice Pirot
A lock solution composed of gentamicin sulfate (5 mg/mL) and ethylenediaminetetraacetic acid disodium salt (EDTA-Na2 , 30 mg/mL) could fully eradicate in vivo bacterial biofilms in totally implantable venous access ports (TIVAP). In this study, fabrication, conditioning and sterilization processes of antimicrobial lock solution (ALS) were detailed and completed by a stability study. Stability of ALS was conducted for 12 months in vial (25 °C ± 2 °C, 60% ± 5% relative humidity (RH), and at 40 °C ± 2 °C, RH 75% ± 5%) and for 24 h and 72 h in TIVAP (40 °C ± 2 °C, RH 75% ± 5%)...
December 2018: Journal of Pharmaceutical Analysis
Ceder H van den Bosch, J Tjomme van der Bruggen, Florine N J Frakking, Cecilia E J Terwisscha van Scheltinga, Cornelis P van de Ven, Martine van Grotel, Lianne M Wellens, Yvette G T Loeffen, Marta Fiocco, Marc H W A Wijnen
BACKGROUND: Central venous access device (CVAD)-related complications are associated with high morbidity rates. This study was performed to underline the importance of CVAD-complication prevention and treatment. METHODS: An audit of practice of CVAD-related complications in pediatric oncology patients receiving a CVAD between January 2015 and June 2017 was performed. CVADs included were totally implantable venous access ports (TIVAPs), Hickman-Broviac® (HB), nontunneled, and peripherally inserted CVADs...
October 30, 2018: Journal of Pediatric Surgery
Xin-Yan Yu, Jia-Lan Xu, Dan Li, Zi-Fang Jiang
The aim of this study was to assess the incidence rate and the risk factors for late complications associated with use of central totally implanted venous access devices (TIVAPs) in patients with cancer, and to devise nursing strategies to minimize late complications.This retrospective study included 500 patients with TIVAPs from 2012 to 2015. Multivariable logistic regression analysis was performed to assess the effect of sex, age, primary diagnosis, duration of surgery, and the length of hospital stay on the incidence of late complications of TIVAP...
September 2018: Medicine (Baltimore)
Teresa Schreckenbach, Indra Münch, Hanan El Youzouri, Wolf Otto Bechstein, Nils Habbe
OBJECTIVE: The implantation of totally implantable venous access ports (TIVAPs) is one of the first procedures surgical residents learn. Complications after implantation procedures have a major impact on patient outcomes, as it may lead to a delay of chemotherapy regimens or of parenteral nutrition. The aim of this study was to compare the outcomes after totally implantable venous access ports implantations done by resident and attending surgeons. DESIGN: The study was performed as a retrospective analysis...
August 14, 2018: Journal of Surgical Education
Xingwei Sun, Jin Xu, Rui Xia, Caishan Wang, Ziyang Yu, Jian Zhang, Xuming Bai, Yong Jin
BACKGROUND: Totally implantable venous access ports (TIVAPs) are widely used and are an essential tool in the efficient delivery of chemotherapy. This study aimed to evaluate the feasibility and safety of implantation of ultrasound (US)-guided TIVAPs via the right innominate vein (INV) for adult patients with cancer. METHODS: This study retrospectively reviewed the medical records of 283 adult patients with cancer who underwent US-guided INV puncture for TIVAPs between September 2015 and September 2017...
July 26, 2018: European Journal of Surgical Oncology
Huifen Ye, Junshao Zeng, Wenzhou Qin, Zhao Yang, Ling Yang, Zhitong Wu, Guinian Du
RATIONALE: Rapidly growing mycobacteria (RGM) are well-known causative agents of human infections, particularly in immunocompromised hosts. However, Mycobacterium fortuitum, a predominant organism, in catheter-associated infections, has rarely been documented in totally implantable venous access port (TVIAP)-associated bloodstream infections. PATIENT CONCERNS: A 25-year-old woman with breast cancer presented to hospital with repeated fever for several days. The patient first refused to remove the TVIAP in her body, and had a relapse of M...
July 2018: Medicine (Baltimore)
Mikhail Cherkashin, Natalia Berezina, Denis Puchkov, Kirill Suprun, Petr Yablonsky
Totally implanted venous access port (TIVAP) systems provide adequate quality of care and life, especially for oncology patients. Long-term vascular access is very important and easy to perform, but in some clinical situations, if patients have a superior caval system occlusion, femoral insertion may be the only option. We present a case of a 70-year-old colorectal adenocarcinoma patient diagnosed with subclavian vein hypoplasia. Her care team decided intraoperatively to implant a port system by the right femoral access...
March 14, 2018: Curēus
Marie Lecronier, Sandrine Valade, Naike Bigé, Nicolas de Prost, Damien Roux, David Lebeaux, Eric Maury, Elie Azoulay, Alexandre Demoule, Martin Dres
BACKGROUND: While no data support this practice, international guidelines recommend the removal of totally implanted venous access ports (TIVAPs) in patients with suspicion of TIVAP-related bloodstream infection admitted in the intensive care unit (ICU) for a life-threatening sepsis. METHODS: During this multicenter, retrospective and observational study, we included all patients admitted in five ICU for a life-threatening sepsis in whom a TIVAP was removed between January 2012 and December 2014...
March 27, 2018: Annals of Intensive Care
Shin-Seok Yang, Moon Sang Ahn
BACKGROUND: The objective of the study was to evaluate the safety, technical feasibility, and complications of totally implanted venous access ports (TIVAPs) in the upper arm, for comparison with transjugular chest ports in patients with breast cancer. METHODS: In total, 223 consecutive female breast cancer patients who received a TIVAP in the upper arm or chest between July 2014 and February 2016 were included. All procedures were performed via a sonographic and fluoroscopic-guided approach using the Seldinger technique under local anesthesia...
July 2018: Annals of Vascular Surgery
Susanne Anton, T Oechtering, E Stahlberg, F Jacob, M Kleemann, J Barkhausen, J P Goltz
PURPOSE: The aim of this paper is to evaluate the safety and efficacy of endovascular revascularization of malignant superior vena cava syndrome (SVCS) and simultaneous implantation of a totally implantable venous access port (TIVAP) using a dual venous approach. MATERIALS AND METHODS: Retrospectively, 31 patients (mean age 67 ± 8 years) with malignant CVO who had undergone revascularization by implantation of a self-expanding stent into the superior vena cava (SVC) (Sinus XL®, OptiMed, Germany; n = 11 [Group1] and Protégé ™ EverFlex, Covidien, Ireland; n = 20 [Group 2]) via a transfemoral access were identified...
June 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Franziska A Stressmann, Elodie Couve-Deacon, Delphine Chainier, Ashwini Chauhan, Aimee Wessel, Sylvaine Durand-Fontanier, Marie-Christine Escande, Irène Kriegel, Bruno Francois, Marie-Cécile Ploy, Christophe Beloin, Jean-Marc Ghigo
Totally implanted venous access ports (TIVAPs) are commonly used catheters for the management of acute or chronic pathologies. Although these devices improve health care, repeated use of this type of device for venous access over long periods of time is also associated with risk of colonization and infection by pathogenic bacteria, often originating from skin. However, although the skin microbiota is composed of both pathogenic and nonpathogenic bacteria, the extent and the consequences of TIVAP colonization by nonpathogenic bacteria have rarely been studied...
September 2017: MSphere
Annika R Keulers, Lilian Kiesow, Andreas H Mahnken
PURPOSE: Platelet counts <50/nl are often considered a contraindication for surgical and interventional radiology procedures. Yet, there are patients requiring totally implantable venous access ports (TIVAP) in whom normalization of the coagulation state is not feasible. This retrospective study evaluates the safety of interventional radiological TIVAP implantation in patients with severe thrombocytopenia. MATERIALS AND METHODS: From 12/2010 to 12/2014, a total 1200 consecutive radiological TIVAP implantations were performed and retrospectively analyzed...
January 2018: Cardiovascular and Interventional Radiology
Kazushi Fujimoto, Hajime Kasai, Toshihiko Sugiura, Koichiro Tatsumi
Patients undergoing chemotherapy usually undergo placement of a totally implantable venous access port (TIVAP), but TIVAP catheter fracture is rare. We encountered a case where flushing the TIVAP catheter became impossible because of resistance. A 61-year-old-woman underwent TIVAP placement. Although a chest X-ray revealed the fractured catheter had migrated into the right hilar area, the timing of the fracture was unclear. Four-dimensional computed tomography (4D-CT) showed that the tip of the fractured catheter was located at the anterior segmental artery of the right upper lobe and was immobile, with the remaining portion flapping with the blood flow...
August 1, 2017: BMJ Case Reports
Eric Voog, Loïc Campion, Pauline du Rusquec, Hugues Bourgeois, Julien Domont, Fabrice Denis, Eric Emmanuel, Olivier Dupuis, Gérard Ganem, Cedrik Lafont, Katell Le Du, Elena Pavluc, Yohan Pointreau, Sophie Roche, Laurence Juhel-Voog, Marie Zinger, Philippe Solal-Celigny
PURPOSE: Totally implantable venous access ports (TIVAP) have been widely used for many years in the management of patients suffering from cancer. The implantation and long-term use of TIVAPs are associated with mechanical, thrombotic, and infectious complications. This is the first exhaustive prospective study of all complications occurring in a whole population on long-term follow-up and therefore allows an objective assessment to be made of the safety of TIVAPs. METHODS: We carried out a prospective single-center observational study...
January 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Tae-Seok Seo, Myung Gyu Song, Jun Suk Kim, Chul Won Choi, Jae Hong Seo, Sang Cheul Oh, Eun Joo Kang, Jae-Kwan Lee, Sung-Yong Lee
PURPOSE: To evaluate long-term clinical outcomes and complications of the single-incision technique for implantation of totally implantable venous access ports (TIVAPs) via the axillary vein. MATERIALS AND METHODS: A total of 932 TIVAPs were placed in 927 patients between May 2012 and October 2014 using a single-incision technique. Patients included 620 men and 307 women with a mean age of 60.0 years. TIVAPs were placed via the left (n = 475) and right (n = 457) axillary veins after making a single oblique vertical incision and medial side pocket without subcutaneous tunneling...
July 14, 2017: Journal of Vascular Access
Raffaele Longo, Mathieu Llorens, Christophe Goetz, Christian Platini, Nada Eid, Jocelyne Sellies, Nadia Ouamara, Philippe Quétin
BACKGROUND: Totally implantable venous access port (TIVAP)-related infections (RIs) remain a serious health problem in cancer patients receiving an intravenous (i.v.) therapy. PATIENTS AND METHODS: The ATAPAC study was a prospective, randomized, monocentric, phase IV trial evaluating the efficacy of taurolidine lock solution versus standard saline solution for primary TIVAP-RI prevention in nonhematological cancer patients receiving i.v. chemotherapy. The primary endpoint was the TIVAP-RI incidence rate...
2017: Oncology
Myung Gyu Song, Tae-Seok Seo, Baek-Hui Kim, Jeong Ho Kim
PURPOSE: To test the hypothesis that mechanical injection of saline is safe and effective in restoring patency of totally implantable venous access ports (TIVAPs) with clot occlusion. We devised an experimental port model for the evaluation of mechanical TIVAP recanalization prior to its clinical application. MATERIALS AND METHODS: The clot TIVAP occlusion model was constructed by filling the catheter with swine blood and incubating it at 37.5°C. The model was incubated for different lengths of time ranging from 1 day to 7 days...
March 21, 2017: Journal of Vascular Access
Michelle Ribeiro Viana Taveira, Luciana Santana Lima, Cláudia Corrêa de Araújo, Maria Júlia Gonçalves de Mello
BACKGROUND: Totally implantable venous access ports (TIVAPs) are used for prolonged central venous access, allowing the infusion of chemotherapy and other fluids and improving the quality of life of children with cancer. TIVAPs were developed to reduce the infection rates associated with central venous catheters; however, infectious events remain common and have not been fully investigated in pediatric oncology patients. PROCEDURE: A retrospective cohort was formed to investigate risk factors for central line-associated bloodstream infection (CLABSI) in pediatric cancer patients...
February 2017: Pediatric Blood & Cancer
Kazuya Kato, Yoshiaki Iwasaki, Kazuhiko Onodera, Mineko Higuchi, Kimitaka Kato, Yurina Kato, Minoru Matsuda, Seiya Endo, Yuko Kobashi, Masahiko Taniguchi
BACKGROUND AND PURPOSE: We aimed to determine the success rate and any complications using a percutaneous approach to the femoral vein (FV) for placement of a totally implantable access port (TIVAP), with a preoperative assessment of the femoral and iliac veins using computed tomography-venography (CT-V). METHODS: A prospective study of 72 patients was conducted where placement of a TIVAP was attempted via the right FV, with the port placed in the anterior thigh, when subclavian vein or jugular vein access was contraindicated...
December 2016: Journal of Surgical Oncology
Charlie C-T Hsu, Gigi N C Kwan, Hannah Evans-Barns, John A Rophael, Mieke L van Driel
BACKGROUND: Totally implantable venous access ports (TIVAPs) provide patients with a safe and permanent venous access, for instance in the administration of chemotherapy for oncology patients. There are several methods for TIVAP placement, and the optimal evidence-based method is unclear. OBJECTIVES: To compare the efficacy and safety of three commonly used techniques for implanting TIVAPs: the venous cutdown technique, the Seldinger technique, and the modified Seldinger technique...
August 21, 2016: Cochrane Database of Systematic Reviews
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