Rui Hua, Mingxi Li, Qingxia Lin, Mengying Dong, Xiaoxuan Gong, Zhenyu Lin, Yule Li, Chen Li, Tian Wu, Chunyue Tan, Wenhao Zhang, Qin Wang, Tianyu Wu, Xiaoyu Zhou, Fang Yang, Chunjian Li
Thrombolytic therapy is one of the most effective treatments for thrombus dissolution and recanalization of blocked vessels in thrombotic diseases. However, the application of the thrombolytic strategy has been limited due to unsatisfactory thrombolytic efficacy, relatively higher bleeding complications, and consequently restricted indications. Recombinant staphylokinase (r-SAK) is a third-generation thrombolytic agent produced by genetic engineering technology, which exhibits a better thrombolytic efficacy than urokinase and recombinant streptokinase...
April 16, 2024: ACS Applied Materials & Interfaces