Sonam Ansel, Xiangfei Yan, Peter Chong, Steven Lo, Mark McCleery, Ashish Mahendra, Elaine MacDuff, Fiona Cowie, Ioanna Nixon, Jeff White
BACKGROUND: This case reports the synchronous diagnosis of two rare unrelated diseases; leiomyosarcoma and tenosynovial giant cell tumor of the knee. It focuses on the challenges of diagnosing tenosynovial giant cell tumor, including cognitive biases in clinical medicine that delay diagnosis. It also demonstrates the pathogenic etiology of tenosynovial giant cell tumor, evidenced by the transient deterioration of the patients' knee symptoms following the administration of prophylactic granulocyte colony-stimulating factor given as part of the chemotherapeutic regime for leiomyosarcoma...
October 6, 2023: Journal of Medical Case Reports