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"Carbon Monoxide" AND "Poisoning" AND "Emergency"

I Altintop, M E Akcin, M Tatli, M S Ilbasmis
Carbon monoxide poisoning (COP) is one of the most common types of potentially fatal poisoning throughout the world. Hyperbaric oxygen therapy (HBOT) is an effective and quick response modality that clears symptoms and prevents sequelae. HBOT should be administered within 4-6 hours after poisoning. The aim of this study was to contribute COP treatment protocols by retrospectively examining the results of COP cases who were administered HBOT according to clinical and laboratory findings at the Emergency Department...
September 30, 2018: Annals of Burns and Fire Disasters
Il Jae Wang, Seok-Ran Yeom, Sung-Wook Park, Sung-Hwa Lee, Sang-Kyoon Han, Soon-Chang Park, Ji-Ho Ryu, Seong-Youn Hwang
PURPOSE: We aimed to examine the utility of the Poison Severity Score (PSS) and Sequential Organ Failure Assessment (SOFA) score as early prognostic predictors of short-term outcomes in patients with carbon monoxide (CO) poisoning. We hypothesized that both the PSS and the SOFA score would be useful prognostic tools. METHODS: This was retrospective observational study of patients with CO poisoning who presented to the emergency department and were admitted for more than 24 hours...
2019: PloS One
Won Gu Lee
Carbon monoxide (CO) poisoning is one of the most serious medical emergencies causing life-threatening conditions, including cardiovascular and neurological sequelae. Acute CO poisoning can lead to myocardial ischemia, ventricular arrhythmia, syncope, seizures, and coma. Seizures and other neurological complications in the early stages of presentation are related to severe intoxication in CO poisoning. In such situations, aggressive hyperbaric oxygen therapy is recommended. In CO poisoning, non-convulsive status epilepticus has rarely been observed following hyperbaric oxygen therapy (HBO2 )...
December 2018: Journal of Epilepsy Research
L Eichhorn, M Kieback, D Michaelis, M Kemmerer, B Jüttner, K Tetzlaff
BACKGROUND: The symptoms of acute carbon monoxide (CO) poisoning are unspecific, ranging from headaches to unconsciousness and death. In addition to acute symptoms, delayed severe neurological sequelae may occur. While a total of 440 deaths by CO poisoning were registered in Germany in 1999, a total of 594 patients died (0.73 per 100,000 inhabitants) in 2014 and in 2015 the number even increased to 648 deaths. A national database on clinical symptoms, course of illness or quality of care concerning CO poisoning does not yet exist...
February 21, 2019: Der Anaesthesist
Abdullah Yazar, Fatih Akin, Ahmet Sert, Esra Türe, Cemile Topcu, Alaaddin Yorulmaz, Fatih Ercan
OBJECTIVE: Carbon monoxide poisoning (COP) is the leading cause of mortality and morbidity due to poisoning worldwide. Because children are affected more quick and severely from COP, they may require a longer treatment period, even if carboxyhemoglobin (CO-Hb) and/or lactate levels return to normal. Therefore, a new marker that predicts the duration of treatment and the final outcomes of COP is needed. METHODS: This case control study was conducted on 32 carbon monoxide-poisoned patients younger than 18 years who had been admitted to pediatric emergency department...
February 8, 2019: Pediatric Emergency Care
Ibrahim Ulas Ozturan, Elif Yaka, Selim Suner, Asim Enes Ozbek, Cansu Alyesil, Nurettin Ozgur Dogan, Serkan Yilmaz, Murat Pekdemir
BACKGROUND: Acute carbon monoxide poisoning is a common environmental emergency worldwide. Treatment options are limited to normobaric oxygen therapy with a nonrebreather face mask or endotracheal tube and hyperbaric oxygen. The aim of this study is to determine the half-life of carboxyhemoglobin (COHb) in adult patients admitted to the emergency department with acute carbon monoxide poisoning receiving high flow nasal cannula (HFNC) oxygen. Device tolerability and patient comfort with the high flow nasal cannula were also evaluated...
January 28, 2019: Clinical Toxicology
Onder Tomruk, Kıvanç Karaman, Bulent Erdur, Hamit Hakan Armagan, Nesrin Gökben Beceren, Alten Oskay, Haci Ahmet Bircan
BACKGROUND High-flow nasal cannula (HFNC) is an alternative to conventional normobaric oxygen therapy (NBO) for hypoxemic patients. Since nothing is known about its effect on carbon monoxide (CO) poisoning, we hypothesized that HFNC might be a useful device in the treatment of CO poisoning victims. MATERIAL AND METHODS We retrospectively reviewed the medical records of patients who were admitted consecutively to the emergency department with CO intoxication. Patients were divided into 2 groups: patients treated with HFNC and patients treated with conventional face mask (CFM)...
January 21, 2019: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Marieke Jüttner, Hella Körner-Göbel, Henning Starke, Sascha Enax, Hendrik Eismann, Volker Göbel, Lars Eichhorn, Björn Jüttner
BACKGROUND: Carbon monoxide poisoning (COP) is the most common cause for poisoning by inhalation in Germany. In the past 8 years, a marked increase in the number of COP-related deaths has been registered nationwide. A national German guideline is missing. METHODS: The national and international literature was screened systematically. Existing international guidelines and expert recommendations for the diagnosis and treatment of COP were compared and evaluated. Furthermore, quality of health care was analyzed by a prospective preclinical dataset of emergency rescue services and retrospective analysis of routine data from 2014 to 2016 in Germany...
December 28, 2018: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
J M Moon, B J Chun, S D Lee, M H Shin
This study investigated whether hyperthermia within the first 24 h after presentation was associated with long-term neurological outcomes after acute carbon monoxide (CO) poisoning. This retrospective study included 200 patients with acute severe CO poisoning. Hyperthermia (≥ 37.5°C) developed during the first 24 h after presentation in 55 (27.5%) patients, and poor long-term neurological sequelae assessed at 23 months after acute CO poisoning developed in 19.5% of the patients. The incidence of poor long-term neurological outcomes was significantly higher in the hyperthermia group than in the normothermia group...
December 14, 2018: Human & Experimental Toxicology
Hamza Sunman, Tolga Çimen, Mehmet Erat, Kadriye Gayretli Yayla, Tolga Han Efe, Seda Özkan, Engin Deniz Arslan, Sadık Açıkel
Objectives: Elevated red blood cell distribution width (RDW) is an independent prognostic factor for cardiovascular events that are major causes of mortality in patients with carbon monoxide (CO) poisoning. Due to the limited number of studies, we aimed to investigate the relationship between RDW levels and long-term mortality for these patients. Method: This retrospective study included patients with CO poisoning, who presented to the emergency department. Baseline characteristics, laboratory results and survival status were retrieved from patients' hospital records...
December 2018: Turkish Journal of Emergency Medicine
Shu-Chen Liao, Yan-Chiao Mao, Kun-Ju Yang, Kuo-Cheng Wang, Li-Ying Wu, Chen-Chang Yang
OBJECTIVES: Delayed neuropsychiatric sequelae (DNS) are serious complications of carbon monoxide poisoning; neuropsychiatric disorders can occur within a few days of recovery from acute poisoning. Hyperbaric oxygen therapy (HBOT) has been the main treatment of carbon monoxide (CO) poisoning and was recommended as the treatment choice for CO poisoning by the American Undersea and Hyperbaric Medical Society and the Tenth European Consensus Conference on Hyperbaric Medicine of the European Underwater and Baromedical Society...
November 22, 2018: Journal of the Neurological Sciences
Radek Vančata, Jan Lhotský, Václav Beránek, Josef Krištof, Richard Rokyta
Severe carbon monoxide intoxication may cause tissue injury by hypoxemia and histotoxicity. The affection of the heart muscle often leads to transient global or regional systolic dysfunction of left ventricle or both ventricles and increased occurences of malignant arrhytmias. On the contrary, stress-induced cardiomyopathy is described as temporary segmental loss of contractility, mostly in apical segments of the left ventricle with mid- and basal sparing and less common hypokinesias in mid- or basal parts, or affection of both ventricles...
2018: Vnitr̆ní Lékar̆ství
Shu-Chen Liao, Yan-Chiao Mao, Yao-Min Hung, Ching-Hsing Lee, Chen-Chang Yang
Objective: Delayed neuropsychiatric sequelae (DNS) are serious complications of carbon monoxide (CO) poisoning that adversely affect poisoned patients' quality of life as well as socioeconomic status. This study aimed to determine clinical predictors of DNS in patients with CO poisoning. Methods: This retrospective study included all CO-poisoned patients admitted to the emergency department (ED) of Linkou Chang Gung Memorial Hospital in Taiwan from 1 January 2009 to 31 December 2015...
2018: BioMed Research International
Caner Turan, Eylem Ulas Saz
OBJECTIVE: Children are presented with an unknown intoxication at emergency department (ED) after carbon monoxide (CO) poisoning. Although CO poisoning is well defined in the adult literature, little information exists regarding CO poisoning in childhood, especially in infants. The only diagnostic test for CO poisoning is elevation of the carboxyhemoglobin level in the blood. CASE: We report the second youngest neonate in literature who was severely poisoned by CO and treated with hyperbaric oxygen at the ED...
October 17, 2018: Pediatric Emergency Care
Aleksandra Świderska, Marek Wiśniewski, Marek Wiergowski, Anna Krakowiak, Jacek Sein Anand
BACKGROUND: Poisonings constitute a significant medical, social and economic problem worldwide. In Poland there is no nationwide registry of poisonings, which results in a lack of accurate epidemiological data. Few publications dealing with the problem are based on data obtained from toxicology units and therefore do not include information about cases treated at emergency departments and other non-toxicology units. METHODS: We analyzed all admissions due to poisonings reported to the Polish National Health Fund by all hospital units in Poland in the 2009-2011 period...
October 10, 2018: BMC Pharmacology & Toxicology
Wei-Chih Liao, Wen-Chien Cheng, Biing-Ru Wu, Wei-Chun Chen, Chih-Yu Chen, Chia-Hung Chen, Chih-Yen Tu, Te-Chun Hsia
BACKGROUND: Carbon monoxide (CO), a colorless and odorless gas, is one of the common causes of poisoning-related deaths worldwide. CO poisoning can result in hypoxic brain damage and death, but intensive care can improve the likely outcome for critically ill patients. However, there is a paucity of clinical data regarding the prognostic factors and association between organ dysfunction and clinical outcome of patients treated for CO poisoning in the intensive care unit (ICU). METHODS: We performed a retrospective study of patients admitted to a university affiliated hospital ICU between July 2001 and December 2010 following CO poisoning...
October 5, 2018: Journal of the Formosan Medical Association
Lihong Zhou, Liming Yuan, Davood Bahrami, Richard A Thomas, James H Rowland
The primary danger with underground mine fires is carbon monoxide poisoning. A good knowledge of smoke and carbon monoxide movement in an underground mine during a fire is of importance for the design of ventilation systems, emergency response, and miners' escape and rescue. Mine fire simulation software packages have been widely used to predict carbon monoxide concentration and its spread in a mine for effective mine fire emergency planning. However, they are not highly recommended to be used to forecast the actual carbon monoxide concentration due to lack of validation studies...
2018: Journal of Fire Sciences
Hyukhoon Kim, Sangchun Choi, Eunjung Park, Eunhui Yoon, Younggi Min, Samsun Lampotang
OBJECTIVE: Reliable biomarkers of delayed neuropsychological sequelae (DNS) after acute carbon monoxide (CO) poisoning are lacking. This study investigated the associations between potential serum markers and the development of DNS after acute CO poisoning. METHODS: Retrospective chart reviews were conducted for patients diagnosed with acute CO poisoning during a 28-month period. The patients were divided into two groups according to the presence or absence of having developed DNS...
September 2018: Clinical and Experimental Emergency Medicine
Abuzer Coşkun, Fatma Ayşen Eren, Şevki Hakan Eren, İlhan Korkmaz
OBJECTIVE: Carbon monoxide (CO) poisoning is very common worldwide. In this study, we aimed to evaluate the predictivity of neuro psychosis in carbon monoxide poisoning by the admission levels of red cell distribution (RDW), mean platelet volume (MPV) and troponin I levels which can be measured quickly and easily in the emergency department (ED). PATIENTS AND METHODS: This single center observational study included a total of 216 consecutive patients who presented to the ED due to CO poisoning between January 2009 and December 2013...
September 15, 2018: American Journal of Emergency Medicine
Marcos Vieira Godinho, Cíntia Elias Pires, Luiz Celso Hygino da Cruz
Our purpose is to describe typical computed tomography and magnetic resonance imaging findings in encephalopathies in the emergency. The focus of this article are the most frequent toxic and acquired metabolic diseases and their preferential sites of involvement, such as hepatic encephalopathy, hypoglicemia, nonketotic hyperglycemia, osmotic demyelination, posterior reversible encephalopathy syndrome, uremia, illegal drug abuse, carbon monoxide poisoning, and hypoxic-ischemic encephalopathy. The radiologist must be able to identify the most usual patterns of lesion in computed tomography and magnetic resonance imaging in these settings...
October 2018: Seminars in Ultrasound, CT, and MR
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