Jordan Morningstar, Jangwoen Lee, Tara Hendry-Hofer, Alyssa Witeof, L Tiffany Lyle, Gregg Knipp, Calum A MacRae, Gerry R Boss, Randall T Peterson, Vincent J Davisson, Robert E Gerszten, Vikhyat S Bebarta, Sari Mahon, Matt Brenner, Anjali K Nath
Cyanide is a highly toxic industrial chemical that is widely used by manufactures. Smoke inhalation during household fires is the most common source of cyanide poisoning while additional risks to civilians include industrial accidents and terrorist attacks. Despite the risks to large numbers of individuals, an antidote capable of administration at scale adequate for a mass casualty, prehospital scenario does not yet exist. Previously, we demonstrated that intravenous cisplatin analogues accelerate recovery from cyanide poisoning in mice and rabbits...
February 2019: FASEB BioAdvances