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("Cast" OR "Splint") AND "Application" AND "Emergency"

Alison J Dittmer, Domingo Molina, Cale A Jacobs, Janet Walker, Ryan D Muchow
INTRODUCTION: Following closed reduction and initial casting of pediatric forearm fractures, loss of reduction (LOR) occurs in ∼5% to 75% of fractures. Sugar-tong splinting has been shown to maintain acceptable reduction in pediatric distal radius fractures while potentially avoiding issues associated with circumferential casting. We hypothesized that the sugar-tong splint would be an acceptable method for initial immobilization to prevent LOR in distal, mid-shaft, and proximal pediatric forearm fractures...
April 2019: Journal of Pediatric Orthopedics
Meng Li, Xi Wang, Cassandra J Porter, Wei Cheng, Xuan Zhang, Lianjun Wang, Menachem Elimelech
Forward osmosis (FO), an emerging membrane separation process, can potentially treat textile wastewaters with less fouling than pressure-driven membrane processes such as reverse osmosis and nanofiltration. However, conventional FO membranes with asymmetric architecture experience severe flux decline caused by internal concentration polarization and fouling as dye molecules accumulate on the membrane surface. In this study, we present a new strategy for concentrating dye by using a self-standing, support-free FO membrane with a symmetric structure...
February 25, 2019: Environmental Science & Technology
Dmitry Iakovlev, Sijung Hu, Vincent Dwyer
Imaging photoplethysmography (iPPG) is an emerging technology used to assess microcirculation and cardiovascular signs by collecting backscattered light from illuminated tissue using optical imaging sensors. An engineering approach is used to evaluate whether a silicone cast of a human palm might be effectively utilized to predict the results of image registration schemes for motion compensation prior to their application on live human tissue. This allows us to establish a performance baseline for each of the algorithms and to isolate performance and noise fluctuations due to the induced motion from the temporally changing physiological signs...
December 8, 2018: Sensors
Donatas Gesevičius, Antonia Neels, Sergii Yakunin, Erwin Hack, Maksym V Kovalenko, Frank Nüesch, Jakob Heier
The superweak tetrakis(nonafluoro-tert-butoxy)aluminate coordinating anion was employed to introduce pseudo-gas-phase conditions to the 2-[5-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1,3-pentadien-1-yl]-1,3,3-trimethyl-3H-indolium chromophore. The resulting formation of a photoactive organic-inorganic hybrid salt has led to a highly stabilized excited state of the organic chromophore mainly due to the minimized lattice energy and Coulomb interactions. These highly beneficial features caused by the well dispersed negative charge of the anion have led to an enhanced neat spin-casted film fluorescence intensity, prolonged fluorescence lifetime, smooth thin film surfaces and a record power photovoltaic efficiency of 3...
November 28, 2018: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
Yoko Kurosaki, Takuya Mino, Kenji Maekawa, Koji Izumi, Takuo Kuboki
PURPOSE: This report was written to introduce an attempt at clinical application of our newly developed digital workflow to reproduce the morphology of the subgingival contour and the emergence profile of the provisional restoration within the final bone-anchored fixed restoration, using a bounded unilateral edentulous case. METHODS: This digital workflow involves superimposition of the composite images of two specific types of working casts onto the working cast for the provisional restoration namely, a split cast screwed with a titanium base and a split cast screwed with a provisional restoration and integrating these with the whole intraoral surface image, in which the provisional restoration was present...
November 16, 2018: Journal of Prosthodontic Research
Alison J Dittmer, Domingo Molina, Cale A Jacobs, Janet Walker, Ryan D Muchow
INTRODUCTION: Following closed reduction and initial casting of pediatric forearm fractures, loss of reduction (LOR) occurs in ∼5% to 75% of fractures. Sugar-tong splinting has been shown to maintain acceptable reduction in pediatric distal radius fractures while potentially avoiding issues associated with circumferential casting. We hypothesized that the sugar-tong splint would be an acceptable method for initial immobilization to prevent LOR in distal, mid-shaft, and proximal pediatric forearm fractures...
November 20, 2018: Journal of Pediatric Orthopedics
Ana R Cardoso, Ana C Marques, Lídia Santos, Alexandre F Carvalho, Florinda M Costa, Rodrigo Martins, M Goreti F Sales, Elvira Fortunato
Graphene has emerged as a novel material with enhanced electrical and structural properties that can be used for a multitude of applications from super-capacitors to biosensors. In this context, an ultra-sensitive biosensor was developed using a low-cost, simple and mask-free method based on laser-induced graphene technique for electrodes patterning. The graphene was produced on a polyimide substrate, showing a porous multi-layer structure with a resistivity of 102.4 ± 7.3 Ω/square. The biosensor was designed as a 3-electrode system...
January 15, 2019: Biosensors & Bioelectronics
F Vigouroux, C Choufani, A Grosset, O Barbier, S Rigal, L Mathieu
The purpose of this report was to analyze sequential management of patients with combat-related hand injuries in the Kabul International Airport Combat Support Hospital and to identify principles of hand damage control orthopedics (DCO). A retrospective study was conducted using the French Opex data system that included all the patients who received sequential treatment for combat-related hand injuries from 2009 to 2013. Demographics, mechanism, injury pattern, reasons for DCO application and surgical procedures performed during initial and definitive treatment were described...
October 14, 2018: Hand Surgery and Rehabilitation
M Manoj, C Muhamed Ashraf, M Jasna, K M Anilkumar, B Jinisha, V S Pradeep, S Jayalekshmi
Lithium-sulfur (Li-S) cells are emerging as the dominant constituents of the next generation battery technology, offering high theoretical capacity around 1675 mA h g-1 and the additional advantages of low cost and non-toxic nature. Activated carbon, derived from natural resources is being extensively investigated for applications as electrode materials in high power supercapacitors and for making composite electrodes for designing high energy density electrochemical cells. The present work is aimed at introducing the potential of the composite cathode of sulfur with the biomass-derived, steam activated carbon (AC) along with the free-standing and flexible film of carbon nanotubes as the interlayer for designing efficient Li-S cells...
February 1, 2019: Journal of Colloid and Interface Science
Hend Mohamed Anter, Irhan Ibrahim Abu Hashim, Walaa Awadin, Mahasen Mohamed Meshali
Purpose: Recently, Apocynin (APO) has emerged as a bioactive phytochemical with potent antioxidant and anti-inflammatory properties. No reports have been published so far concerning its topical application as a pharmaceutical dosage form for prospective use. To the best of our knowledge, this is the first study to fabricate novel anti-inflammatory film for external medication with APO. Methods: APO film was prepared using casein (CAS) as a natural protein film former by solvent casting technique...
2018: Drug Design, Development and Therapy
M Catherine Sargent
Use of a single-leg spica cast for femoral fractures in ambulatory children 1 to 5 years of age facilitates care and mobilization of the patient. It may allow a shorter duration of cast treatment than is possible with a traditional one and one-half-leg spica cast, particularly in patients 1 to 3 years of age. The single-leg spica is indicated for children who are small enough to be lifted safely in the cast and who have an isolated, closed, low-energy femoral shaft fracture. The procedure consists of the following steps:Step 1: Obtain adequate sedation...
September 28, 2017: JBJS Essential Surgical Techniques
Jennifer M Foster, Mary Ruth McDonald
In the last 5 years, asparagus acreage in Canada has increased by over 25%. Stemphylium leaf spot, caused by Stemphylium vesicarium, has emerged as the predominant foliar pathogen of asparagus. Typically, contact fungicides are applied every 14 days; however, regardless of the number of applications, growers are not achieving adequate control of the disease. The TOM-CAST forecasting model is used widely in Michigan asparagus fields, but it has never been assessed for suitability in Ontario or in the popular cultivar, Guelph Millennium...
November 2018: Plant Disease
Brittany O Aicher, Subhradip Mukhopadhyay, Xin Lu, Selen C Muratoglu, Dudley K Strickland, Areck A Ucuzian
Aortic aneurysm and dissection is associated with significant morbidity and mortality in the population and can be highly lethal. While animal models of aortic disease exist, in vivo imaging of the vasculature has been limited. In recent years, micro-computerized tomography (micro-CT) has emerged as a preferred modality for imaging both large and small vessels both in vivo and ex vivo. In conjunction with a method of vascular casting, we have successfully used micro-CT to characterize the frequency and distribution of aortic pathology in β-aminopropionitrile-treated C57/Bl6 mice...
July 16, 2018: Journal of Visualized Experiments: JoVE
Tyler J Slade, Jann A Grovogui, Shiqiang Hao, Trevor P Bailey, Runchu Ma, Xia Hua, Aurélie Guéguen, Ctirad Uher, Chris Wolverton, Vinayak P Dravid, Mercouri G Kanatzidis
Thermoelectric devices directly convert heat into electrical energy and are highly desired for emerging applications in waste heat recovery. Currently, PbTe based compounds are the leading thermoelectric materials in the intermediate temperature regime (∼800 K); however, integration into commercial devices has been limited. This is largely because the performance of PbTe, which is maximized ∼900 K, is too low over the temperatures of interest for most potential commercial applications (generally under 600 K)...
June 6, 2018: Journal of the American Chemical Society
Nathanaël Hozé, Sebastian Bonhoeffer, Roland Regoes
Disease tolerance is a defense strategy against infections that aims at maintaining host health even at high pathogen replication or load. Tolerance mechanisms are currently intensively studied with the long-term goal of exploiting them therapeutically. Because tolerance-based treatment imposes less selective pressure on the pathogen it has been hypothesised to be "evolution-proof". However, the primary public health goal is to reduce the incidence and mortality associated with a disease. From this perspective, tolerance-based treatment bears the risk of increasing the prevalence of the disease, which may lead to increased mortality...
May 2018: PLoS Computational Biology
Ankita R Desai, Furqan A Maulvi, Mihir M Pandya, Ketan M Ranch, Bhavin A Vyas, Shailesh A Shah, Dinesh O Shah
Glaucoma is a chronic disease, which is currently treated using frequent high dose applications of an eye drop solution; this method is tedious, and most of patients are non-compliant to it. Contact lenses are emerging as a convenient option to sustain the release of ophthalmic drugs. However, the incorporation of a drug/formulation changes the optical and physical properties of contact lenses. Contact lens users have also reported pink eye syndrome; this makes contact lenses unsuitable to be accepted as a medical device...
May 29, 2018: Biomaterials Science
Peng Zhang, Priyesh Jain, Caroline Tsao, Zhefan Yuan, Wenchen Li, Bowen Li, Kan Wu, Hsiang-Chieh Hung, Xiaojie Lin, Shaoyi Jiang
The commonly used "stealth material" poly(ethylene glycol) (PEG) effectively promotes the pharmacokinetics of therapeutic cargos while reducing their immune response. However, recent studies have suggested that PEG could induce adverse reactions, including the emergence of anti-PEG antibodies and tissue histologic changes. An alternative stealth material with no or less immunogenicity and organ toxicity is thus urgently needed. We designed a polypeptide with high zwitterion density (PepCB) as a stealth material for therapeutics...
June 25, 2018: Angewandte Chemie
David de Gonzalo-Calvo, Angela Vea, Christian Bär, Jan Fiedler, Liam S Couch, Carlos Brotons, Vicenta Llorente-Cortes, Thomas Thum
Current clinical guidelines emphasize the unmet need for technological innovations to guide physician decision-making and to transit from conventional care to personalized cardiovascular medicine. Biomarker-guided cardiovascular therapy represents an interesting approach to inform tailored treatment selection and monitor ongoing efficacy. However, results from previous publications cast some doubts about the clinical applicability of biomarkers to direct individualized treatment. In recent years, the non-coding human transcriptome has emerged as a new opportunity for the development of novel therapeutic strategies and biomarker discovery...
April 24, 2018: European Heart Journal
Shan Ding, Shibao Xie, Weiquan Chen, Lu Wen, Junyi Wang, Fan Yang, Gang Chen
Drug delivery to the inner ear by nanomedicine strategies has emerged as an effective therapeutic approach for the management of inner ear diseases including hearing and balance disorders. It is well accepted that substance enters the perilymph from the middle ear through the round window membrane (RWM), but the passage through the oval window (OW) has long been neglected. Up to now, researchers still know little about the pathway via which nanoparticles (NPs) enter the inner ear or how they reach the inner ear following local applications...
February 28, 2018: European Journal of Pharmaceutical Sciences
Marcello Ienca, Effy Vayena, Alessandro Blasimme
Emerging trends in pervasive computing and medical informatics are creating the possibility for large-scale collection, sharing, aggregation and analysis of unprecedented volumes of data, a phenomenon commonly known as big data. In this contribution, we review the existing scientific literature on big data approaches to dementia, as well as commercially available mobile-based applications in this domain. Our analysis suggests that big data approaches to dementia research and care hold promise for improving current preventive and predictive models, casting light on the etiology of the disease, enabling earlier diagnosis, optimizing resource allocation, and delivering more tailored treatments to patients with specific disease trajectories...
2018: Frontiers in Medicine
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