Yiqi Du, Tun Su, Xinmiao Song, Jun Gao, Duowu Zou, Changjing Zuo, Weifen Xie, Bangmao Wang, Zhiguang Zhang, Jianming Xu, Dean Tian, Hesheng Luo, Zhenyu Zhang, Shaofeng Wang, Jianping Chen, Jizhong Guo, Lei Gong, Yanbing Ding, Zhaoshen Li
GOALS AND BACKGROUND: Functional dyspepsia (FD) is a complex disease with a variety of dyspeptic symptoms. Little is known about the clinical efficacy of cinitapride, a 5-HT₄ agonist and D₂ antagonist, in treating FD. STUDY: This randomized, double-blind, double-dummy, positive-controlled study compared the efficacy and safety of cinitapride (1 mg) and domperidone (10 mg) tid for 4 weeks in 383 consecutive patients with mild to moderate, postprandial distress syndrome-predominant dyspeptic symptoms according to Rome III criteria...
April 2014: Journal of Clinical Gastroenterology