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("ECG" OR " EKG") AND ("Ventricular Tachycardia" OR "VT")

Takehito Sasaki, Kohki Nakamura, Shigeto Naito
A 28-year-old female presented with fulminant lymphocytic myocarditis. She developed cardiogenic shock, frequent sustained ventricular tachycardia, and fibrillation (VT and VF). The left ventricular ejection fraction improved from 5% to 40% after medical therapy, but the right ventricular systolic dysfunction and enlargement persisted. In addition, sustained VTs, requiring direct current cardioversion, occurred during oral administration of amiodarone following intravenous amiodarone, even after percutaneous stellate ganglion block...
February 8, 2019: International Heart Journal
Jesús E Dos Reis, Paul Soullié, Alberto Battaglia, Gregory Petitmangin, Philip Hoyland, Laurent Josseaume, Christian de Chillou, Freddy Odille, Jacques Felblinger
Electrocardiogram (ECG) acquisition is required during catheter treatment of cardiac arrhythmias. The remote magnetic navigation technology allows the catheter to be moved automatically inside the heart chambers using large external magnets. Each change of position of the catheter requires fast motion of the magnets, therefore magnetic fluxes are created through the ECG cables, causing large distortions of the ECG signals. In this study a novel ECG sensor is proposed for reducing such distortions. The sensor uses short cables to connect the electrodes to the amplification and optical conversion circuit, using a technology similar to that used for magnetic resonance imaging...
January 30, 2019: Annals of Biomedical Engineering
Sophie I Mavrogeni, Konstantinos Tsarouhas, Demetrios A Spandidos, Christina Kanaka-Gantenbein, Flora Bacopoulou
Athletic pre-participation screening is essential for minimizing the risk for sudden cardiac death (SCD) in athletes participating in either competitive or leisure sporting activities. The primary causes of SCD in young athletes (<35 years of age) include hypertrophic cardiomyopathy, congenital anomalies of the coronary artery and arrhythmogenic right ventricular cardiomyopathy. Other abnormalities, such as malignant arrhythmia due to blunt trauma to the chest (commotio cordis), myocarditis, valvular disease, aortic rupture (in Marfan syndrome) and ion channelopathies (catecholaminergic polymorphic ventricular tachycardia, Brugada syndrome, long or short QT syndrome), also contribute to a lesser degree to SCD...
February 2019: Experimental and Therapeutic Medicine
Xianpei Wang, Lu Zhang, Chuanyu Gao, Sha Wu, Jialu Zhu
BACKGROUND: ST-segment elevation (STE) and an increased Tpeak-Tend interval (Tp-e) have prognostic value for malignant arrhythmia events (MAEs) in patients with ST-segment elevation myocardial infarction (STEMI) and Brugada syndrome. Whether STE could predict MAEs and has an electrophysiological relationship with Tp-e in electrocardiogram (ECG) of vasospastic angina (VA) patients needs to be elucidated. METHODS: Sixty-five patients with VA and 23 patients with VA complicated by MAEs were enrolled...
January 3, 2019: Journal of Electrocardiology
Rajeev K Pathak, Nilshan Ariyarathna, Fermin C Garcia, Prashanthan Sanders, Francis E Marchlinski
Ventricular arrhythmias (VA) are observed in the setting of structural heart disease. However, in a proportion of patients presenting with VT, the routine diagnostic modalities fail to demonstrate overt myocardial abnormality. These arrhythmias have been called idiopathic VAs. They consist of various subtypes that have been defined by their anatomic location of origin within the heart and/or their underlying mechanism. While the majority of patients are asymptomatic, some experience debilitating symptoms and may develop reversible ventricular dysfunction...
January 2019: Heart, Lung & Circulation
Guangqiang Wang, Na Zhao, Chuanhuan Zhang, Shu Zhong, Xuexun Li
RATIONALE: The lambda-like ST-elevation electrocardiography (ECG) pattern is extremely rare in patients with type 2 myocardial infarction (T2MI) triggered by coronary spasm. When this ECG pattern appears, sudden cardiac death (SCD) caused by lethal ventricular arrhythmia may occur because clinicians do not pay sufficient attention to this phenomenon. PATIENT CONCERNS: We describe a 41-year-old man who presented with steep down-sloping ST-segment elevation, paroxysmal ventricular tachycardia, severe sinus bradycardia, and intermittent complete atrioventricular block on ECG during the sudden recurrence of clinical symptoms...
December 2018: Medicine (Baltimore)
Tomas Robyns, Dieter Nuyens, Hua Rong Lu, David J Gallacher, Bert Vandenberk, Christophe Garweg, Joris Ector, Efstathios Pagourelias, Johan Van Cleemput, Stefan Janssens, Rik Willems
INTRODUCTION: Preventing sudden cardiac death (SCD) is one of the main goals in hypertrophic cardiomyopathy (HCM). Many variables have been proposed, however the European and American guidelines do not incorporate any ECG or Holter monitoring derived variables other than the presence of ventricular arrhythmia in their risk stratification models. In the present study we evaluated electrocardiographic parameters in risk stratification of HCM. METHODS AND RESULTS: Novel electrocardiographic parameters including the index of cardio-electrophysiological balance (iCEB), individualized QT correction (QTi) and QT rate dependence were evaluated along with established risk factors...
November 2018: Journal of Electrocardiology
Katja E Odening, Ilona Bodi, Gerlind Franke, Raphaela Rieke, Anna Ryan de Medeiros, Stefanie Perez-Feliz, Hannah Fürniss, Lea Mettke, Konstantin Michaelides, Corinna N Lang, Johannes Steinfurt, Naga Deepa Pantulu, David Ziupa, Marius Menza, Manfred Zehender, Heiko Bugger, Remi Peyronnet, Jan C Behrends, Zoltan Doleschall, Axel Zur Hausen, Christoph Bode, Genevieve Jolivet, Michael Brunner
Aims: Short-QT syndrome 1 (SQT1) is an inherited channelopathy with accelerated repolarization due to gain-of-function in HERG/IKr. Patients develop atrial fibrillation, ventricular tachycardia (VT), and sudden cardiac death with pronounced inter-individual variability in phenotype. We generated and characterized transgenic SQT1 rabbits and investigated electrical remodelling. Methods and results: Transgenic rabbits were generated by oocyte-microinjection of β-myosin-heavy-chain-promoter-KCNH2/HERG-N588K constructs...
November 28, 2018: European Heart Journal
John J Lazarus, Ashraf Saleh, Michael Ghannam, Keith Aaronson, Monica Colvin, Frank Pagani, Todd Koelling, James R Corbett, Richard L Weinberg, Venkatesh L Murthy, Matthew C Konerman
OBJECTIVES: We sought to determine the safety of regadenoson (REG) stress testing in patients who have undergone orthotopic heart transplantation (OHT). BACKGROUND: Routine screening for cardiac allograft vasculopathy (CAV) is necessary after OHT. Adenosine stress is contraindicated after heart transplantation due to supersensitivity in denervated hearts. Safety of regadenoson stress following OHT has not been well studied. METHODS: We retrospectively reviewed data from OHT patients (N = 123) who were referred to REG stress testing...
November 27, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
Yasuhiro Yokoyama, Hitoshi Hachiya, Tomonori Watanabe, Ayako Yokota, Takahiro Komori, Tomoyuki Kabutoya, Yasushi Imai, Kazuomi Kario
Idiopathic ventricular tachycardias (VTs) originating from the non-coronary cusp (NCC) are very rare. The previous reports suggested NCC-VTs were characterized by a narrower QRS duration and smaller III/II ratio than VTs originating from other coronary-cusps. We present a rare case of an NCC-VT with a local fragmented potential recorded at the NCC inconsistent with the known ECG characteristics of NCC-VTs.
November 9, 2018: Journal of Electrocardiology
Minh Tuan Nguyen, Binh Van Nguyen, Kiseon Kim
Ventricular fibrillation and ventricular tachycardia (VF/VT), known as shockable (SH) rhythms, are the mainly cause of sudden cardiac arrests (SCA), which is cured efficiently by the automated external defibrillator (AED). The performance of the shock advice algorithm (SAA) applied in the AED has been improved by using machine learning technique and variously conventional features, recently. In this paper, we propose a novel algorithm with relatively high performance for the SCA detection on electrocardiogram (ECG) signal...
November 21, 2018: Scientific Reports
Suganti Shivaram, Divaakar Siva Baala Sundaram, Rogith Balasubramani, Anjani Muthyala, Shivaram P Arunachalam
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia affecting approximately 3 million Americans, and is a prognostic marker for stroke, heart failure and even death. Current techniques to discriminate normal sinus rhythm (NSR) and AF from single lead ECG suffer several limitations in terms of sensitivity and specificity using short time ECG data which distorts ECG and many are not suitable for real-time implementation. The purpose of this research was to test the feasibility of discriminating single lead ECG's with normal sinus rhythm (NSR) and AF using intrinsic mode function (IMF) complexity index...
July 2018: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Douglas Robinson, Gregory Hand, Jason Ausman, Anthony Hackett
BACKGROUND: Brugada pattern is a well-known pathological finding on electrocardiogram (ECG) which increases the likelihood of cardiac arrest due to ventricular arrhythmia. These cases generally present in younger patients without evidence of an electrolyte abnormality, structural heart disease, or cardiac ischemia. In many instances, this pattern is either hidden on initial presentation or presents as an incidental finding on an EKG. Often times the Brugada syndrome leads to sudden cardiac death or more rarely can be unmasked with a class 1A or 1C anti-arrhythmic agent...
February 2019: American Journal of Emergency Medicine
Jonathan R Skinner, Annika Winbo, Dominic Abrams, Jitendra Vohra, Arthur A Wilde
Forty per cent (40%) of sudden unexpected natural deaths in people under 35 years of age are associated with a negative autopsy, and the cardiac ion channelopathies are the prime suspects in such cases. Long QT syndrome (LQTS), Brugada syndrome (BrS) and catecholaminergic polymorphic ventricular tachycardia (CPVT) are the most commonly identified with genetic testing. The cellular action potential driving the heart cycle is shaped by a specific series of depolarising and repolarising ion currents mediated by ion channels...
October 4, 2018: Heart, Lung & Circulation
Lukas J Motloch, Marine Cacheux, Kiyotake Ishikawa, Chaoqin Xie, Jun Hu, Jaume Aguero, Kenneth M Fish, Roger J Hajjar, Fadi G Akar
Background SERCA 2a gene transfer ( GT ) improves mechano-electrical function in animal models of nonischemic heart failure Whether SERCA 2a GT reverses pre-established remodeling at an advanced stage of ischemic heart failure is unclear. We sought to uncover the electrophysiological effects of adeno-associated virus serotype 1. SERCA 2a GT following myocardial infarction ( MI ). Methods and Results Pigs developed mechanical dysfunction 1 month after anterior MI , at which point they received intracoronary adeno-associated virus serotype 1...
September 18, 2018: Journal of the American Heart Association
Namsik Yoon, Bence Patocskai, Charles Antzelevitch
BACKGROUND: Early repolarization syndrome (ERS) is an inherited cardiac arrhythmia syndrome associated with sudden cardiac death. Approaches to therapy are currently very limited. This study probes the mechanisms underlying the electrocardiographic and arrhythmic manifestation of experimental models of ERS and of the ameliorative effect of radiofrequency ablation. METHODS: Action potentials, bipolar electrograms, and transmural pseudo-ECGs were simultaneously recorded from coronary-perfused canine left ventricular wedge preparations (n=11)...
September 2018: Circulation. Arrhythmia and Electrophysiology
Charlotte Brouwer, Gijsbert F L Kapel, Monique R M Jongbloed, Martin J Schalij, Marta de Riva Silva, Katja Zeppenfeld
OBJECTIVES: This study sought to evaluate the relation between 12-lead ventricular tachycardia (VT) electrocardiography (ECG) and VT-related anatomical isthmuses (AIs) in repaired tetralogy of Fallot (rTOF). BACKGROUND: Slow-conducting AIs are the dominant VT substrate in rTOF. Whether an AI is considered critical relies on pace mapping (PM) guided by the VT ECG. METHODS: VT ECGs, electroanatomical mapping data and PM results were analyzed in 25 rTOF patients (group 1) (age 57 ± 13 years)...
October 2018: JACC. Clinical Electrophysiology
Elisabeth Kaiser, Qinghai Tian, Michael Wagner, Monika Barth, Wenying Xian, Laura Schroeder, Sandra Ruppenthal, Lars Kaestner, Ulrich Boehm, Philipp Wartenberg, Huiyan Lu, Sara M McMillin, Derek B Bone, Jürgen Wess, Peter Lipp
Aims: Signaling via Gq-coupled receptors is of profound importance in many cardiac diseases such as hypertrophy and arrhythmia. Nevertheless, owing to their widespread expression and the inability to selectively stimulate such receptors in vivo, their relevance for cardiac function is not well understood. We here use DREADD technology to understand the role of Gq-coupled signaling in vivo in cardiac function. Methods and Results: We generated a novel transgenic mouse line that expresses a Gq-coupled DREADD (Dq) in striated muscle under the control of the MCK promotor...
October 13, 2018: Cardiovascular Research
Leanne Jane Eveson, A Williams
We present the case of a 50-year-old, fit, asymptomatic gurkha officer. At a routine medical, an ECG showed T-wave inversion in the chest leads V3-6. Transthoracic echo showed left ventricular apical hypertrophy and cavity obliteration consistent with apical hypertrophic cardiomyopathy (ApHCM). Cardiac magnetic resonance imaging showed apical and inferior wall hypertrophy in the left ventricle with no aneurysm or scarring. A 24-hour monitor showed normal sinus rhythm with no evidence of non-sustained ventricular tachycardia...
October 12, 2018: Journal of the Royal Army Medical Corps
Pramod Theetha Kariyanna, Apoorva Jayarangaiah, Sudhanva Hegde, Jonathan D Marmur, Perry Wengrofsky, Mena Yacoub, Michael Post, Samy I McFarlane
Marijuana is the most common drug of abuse in the United States. Marijuana acts on cannabinoid receptors CB1, CB2 and another distinct endothelial receptor. Marijuana is known to cause tachycardia, hypotension and hypertension. Various arrhythmias including atrial fibrillation, atrial flutter, II degree AV block, ventricular fibrillation, ventricular tachycardia, asystole and brugada pattern associated with marijuana use have been reported. We here present an interesting case of Type I Brugada pattern in electrocardiography (ECG) in a 36 year old healthy African American male who presented after smoking four joints...
2018: American journal of medical case reports
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