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Guidelines in diabetes mellitus type II

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https://read.qxmd.com/read/30756197/detecting-secular-trends-in-clinical-treatment-through-temporal-analysis
#1
Douglas Redd, Yijun Shao, Yan Cheng, Qing Zeng-Treitler
Medical treatments change over time for multiple reasons, including introduction of new treatments, availability of new scientific evidence, change in institutional guidelines, and market efforts by pharmaceutical and medical device companies. Monitoring and analyzing these secular trends will also inform the evaluation of evidence based practice as well as outcome research. Using a large national clinical dataset from the United States Veterans Health Administration (VHA), we measured the change in prevalence of all diseases, medications, and procedures by year from 2001 to 2014...
February 12, 2019: Journal of Medical Systems
https://read.qxmd.com/read/30724982/-consensus-statement-of-the-chilean-endocrinological-society-on-the-role-of-bariatric-surgery-in-type-2-diabetes
#2
Jorge Sapunar, Alex Escalona, A Verónica Araya, Carmen Gloria Aylwin, María Juliana Bastías, Camilo Boza, Carlos Cárcamo, Attila Csendes A, Patricio Davidof F, Ricardo Funke, Patricia Gómez, María Isabel González, Rodolfo Lahsen, Enrique Lanzarini, Alberto Maíz, Verónica Mujica, Rodrigo Muñoz, Gustavo Pérez, Félix Raimann, Patricio Salman, Matías Sepúlveda, Néstor Soto, Rodrigo Villagrán
Diabetes Mellitus (DM) and obesity are a public health problem in Chile. Bariatric surgery is the most effective treatment alternative to achieve a significant and sustained weight reduction in patients with morbid obesity. The results of controlled clinical trials indicate that, compared to medical treatment, surgery for obese patients with DM2 allows a better control of blood glucose and cardiovascular risk factors, reduces the need for medications and increases the likelihood for remission. Consensus conferences and clinical practice guidelines support bariatric surgery as an option to treat DM2 in Class III Obesity (Body Mass Index (BMI) > 40) regardless of the glycemic control and the complexity of pharmacological treatment and in Class II Obesity (BMI 35-39,9) with inadequate glycemic control despite optimal pharmacological treatment and lifestyle...
December 2018: Revista Médica de Chile
https://read.qxmd.com/read/30531609/sodium-glucose-cotransporter-2-inhibitors-an-overview-and-perioperative-implications
#3
Amit Bardia, Mabel Wai, Manuel L Fontes
PURPOSE OF REVIEW: Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are a relatively new class of drugs used in the management of diabetes mellitus. This review will highlight key pharmacologic characteristics of this class of drugs; discuss their potential role in management of patients with cardiac disease; and raise several perioperative concerns for anesthesiologists caring for patients on SGLT-2 inhibitors. RECENT FINDINGS: Recent trials have shown a strong mortality benefit in diabetic patients on SGLT 2 inhibitors especially in patients with a high cardiovascular burden...
February 2019: Current Opinion in Anaesthesiology
https://read.qxmd.com/read/30442196/the-quality-of-clinical-practice-guidelines-for-management-of-pediatric-type-2-diabetes-mellitus-a-systematic-review-using-the-agree-ii-instrument
#4
Meha Bhatt, Ahmed Nahari, Pei-Wen Wang, Emily Kearsley, Nicole Falzone, Sondra Chen, Erin Fu, Yaanu Jeyakumar, Justyna Zukowski, Laura Banfield, Lehana Thabane, M Constantine Samaan
AIMS: Pediatric type 2 diabetes mellitus (T2DM) is a relatively new disease with increasing incidence corresponding to the obesity epidemic among youth. It is important for clinicians to have access to high-quality clinical practice guidelines (CPGs) for appropriate management of pediatric patients with T2DM. The objective of this systematic review was to evaluate overall quality of CPGs for the management of pediatric T2DM using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) tool...
November 15, 2018: Systematic Reviews
https://read.qxmd.com/read/30312887/a-validated-lc-ms-ms-method-for-simultaneous-determination-of-linagliptin-and-metformin-in-spiked-human-plasma-coupled-with-solid-phase-extraction-application-to-a-pharmacokinetic-study-in-healthy-volunteers
#5
Bahia Abbas Moussa, Marianne Alphonse Mahrouse, Michael Gamal Fawzy
Combination therapy has a pivotal role in type II diabetes mellitus management in patients unable to maintain normal glycemic level using metformin alone. Addition of linagliptin, dipeptidyl peptidase-IV inhibitor, to metformin improves glycemic control. This study is concerned with the development of an HPLC-MS/MS method for simultaneous quantification of linagliptin and metformin in spiked human plasma. The method was applied to evaluate the potential pharmacokinetic interactions between the cited drugs in healthy volunteers...
October 1, 2018: Journal of Pharmaceutical and Biomedical Analysis
https://read.qxmd.com/read/30143033/pharm-md-an-open-label-randomized-controlled-phase-ii-study-to-evaluate-the-efficacy-of-a-pharmacist-managed-diabetes-clinic-in-high-risk-diabetes-patients-study-protocol-for-a-randomized-controlled-trial
#6
Alexandra Halalau, Daniel Shelden, Scott Keeney, Jaspreet Hehar
BACKGROUND: Millions of Americans are currently living with diabetes and approximately 1.5 million cases are being diagnosed each year. Diabetes is now the seventh leading cause of death in the United States. In addition, the economic burden of the disease has resulted in billions of dollars in health care costs. In spite of these investments, the United States lags behind other developed countries on diabetes life expectancy and disease-related deaths. The purpose of this study is to assess the impact of a pharmacist-managed diabetes clinic (PMDC) model on diabetes core measures...
August 24, 2018: Trials
https://read.qxmd.com/read/30058540/development-and-validation-of-hplc-method-for-the-determination-of-pioglitazone-in-human-plasma
#7
Syed Imran Ali, Nighat Razvi, Syed Mohammad Farid Hasan
Pioglitazone is widely used for the management of type-II diabetes mellitus. The objective of the present study was to develop a simple and cost-effective HPLC method for the quantification of pioglitazone in human plasma. The mobile phase comprises of Acetonitrile, 0.1 M ammonium acetate and glacial acetic acid (25:25:1 v/v/v) at a flow rate of 1.2 mL/min., using Macherey-Nagel Column C18, (dimensions: 5 μm; 250 × 4.6mm) with a guard column. The UV detector was set at 269nm. The method was validated according to FDA guidelines...
July 2018: Pakistan Journal of Pharmaceutical Sciences
https://read.qxmd.com/read/29781721/current-prescription-status-of-antihypertensive-drugs-in-japanese-patients-with-hypertension-analysis-by-type-of-comorbidities
#8
Takayuki Ishida, Akinori Oh, Shinzo Hiroi, Yukio Shimasaki, Takuya Tsuchihashi
In 2014, the Japanese Society of Hypertension (JSH) issued revised guidelines for hypertension management. To assess adherence to the guidelines, this retrospective study evaluated the real-world status of antihypertensive drug prescribing for Japanese patients with hypertension, classified by comorbidity: diabetes mellitus, dyslipidemia, gout/hyperuricemia and renal diseases. Data on 59,867 hypertensive patients who received their first prescription for antihypertensive therapy between April 2014 and March 2015, were obtained from a medical insurance claims database for hospitals participating in the Diagnosis Procedure Combination/Per-Diem payment system...
May 21, 2018: Clinical and Experimental Hypertension: CHE
https://read.qxmd.com/read/29582816/prevalence-progression-and-outcomes-of-diabetic-retinopathy-during-pregnancy-in-indian-scenario
#9
Tarjani Makwana, Brijesh Takkar, Pradeep Venkatesh, Jai Bhagwan Sharma, Yashdeep Gupta, Rohan Chawla, Rajpal Vohra, Alka Kriplani, Nikhil Tandon
Purpose: The objective of this study is to evaluate pattern of diabetic retinopathy (DR) during pregnancy in females with pregestational diabetes mellitus (DM). Methods: This is an ambispective observational cohort study conducted at an Indian tertiary care centre. A total of 50 pregnant females with pregestational DM were included while those with gestational DM were excluded from the study. Ocular examination (inclusive of fundus photography) was conducted and systemic parameters (inclusive of Glycated hemoglobin) were assessed during each of the 3 trimesters and 3 months postpartum...
April 2018: Indian Journal of Ophthalmology
https://read.qxmd.com/read/29507945/hemoglobin-a1c-targets-for-glycemic-control-with-pharmacologic-therapy-for-nonpregnant-adults-with-type-2-diabetes-mellitus-a-guidance-statement-update-from-the-american-college-of-physicians
#10
Amir Qaseem, Timothy J Wilt, Devan Kansagara, Carrie Horwitch, Michael J Barry, Mary Ann Forciea
Description: The American College of Physicians developed this guidance statement to guide clinicians in selecting targets for pharmacologic treatment of type 2 diabetes. Methods: The National Guideline Clearinghouse and the Guidelines International Network library were searched (May 2017) for national guidelines, published in English, that addressed hemoglobin A1c (HbA1c) targets for treating type 2 diabetes in nonpregnant outpatient adults. The authors identified guidelines from the National Institute for Health and Care Excellence and the Institute for Clinical Systems Improvement...
April 17, 2018: Annals of Internal Medicine
https://read.qxmd.com/read/29277343/the-divergent-cardiovascular-effects-of-angiotensin-converting-enzyme-inhibitors-and-angiotensin-ii-type-1-receptor-blockers-in-adult-patients-with-type-2-diabetes-mellitus
#11
REVIEW
Martin H Strauss, Alistair S Hall
The renin angiotensin aldosterone system (RAAS) plays a central role in the pathophysiology of hypertension and vascular disease. Angiotensin-converting enzyme inhibitors (ACEi's) suppress angiotensin II (ANG II) concentrations, whereas angiotensin II type 1 (AT1 ) receptor blockers (ARBs) block the binding of ANG II to AT1 receptors. ACEi's and ARBs are both effective antihypertensive agents and produce similar risk reductions for stroke, a blood pressure-dependent phenomenon. ACEi's also reduce the risk for myocardial infarction (MI) and all-cause mortality in high-risk hypertensive patients as well as in people with diabetes, vascular disease and congestive heart failure...
April 2018: Canadian Journal of Diabetes
https://read.qxmd.com/read/29026763/comparative-evaluation-of-indian-diabetes-risk-score-and-finnish-diabetes-risk-score-for-predicting-risk-of-diabetes-mellitus-type-ii-a-teaching-hospital-based-survey-in-maharashtra
#12
Shivshakti D Pawar, Jayashri D Naik, Priya Prabhu, Gajanan M Jatti, Sachin B Jadhav, B K Radhe
CONTEXT: India is currently becoming capital for diabetes mellitus. This significantly increasing incidence of diabetes putting an additional burden on health care in India. Unfortunately, half of diabetic individuals are unknown about their diabetic status. Hence, there is an emergent need of effective screening instrument to identify "diabetes risk" individuals. AIMS: The aim is to evaluate and compare the diagnostic accuracy and clinical utility of Indian Diabetes Risk Score (IDRS) and Finnish Diabetes Risk Score (FINDRISC)...
January 2017: Journal of Family Medicine and Primary Care
https://read.qxmd.com/read/28956359/metabolic-surgery-in-korea-what-to-consider-before-surgery
#13
REVIEW
Mi Kyung Kim, Yoonseok Heo
Obesity is increasing globally and represents a significant global health problem because it predisposes towards various diseases, such as type 2 diabetes mellitus, cardiovascular disease, degenerative joint disease, and certain types of cancer. Numerous studies have shown that bariatric surgery reduces body mass and ameliorates obesity-related complications, such as hypertension and hyperglycemia, suggesting that surgery is the most effective therapeutic option for severely obese and obese diabetic patients...
September 2017: Endocrinology and Metabolism
https://read.qxmd.com/read/28948654/quality-assessment-of-recent-evidence-based-clinical-practice-guidelines-for-management-of-type-2-diabetes-mellitus-in-adults-using-the-agree-ii-instrument
#14
REVIEW
Muhammad A Anwer, Ousama B Al-Fahed, Samir I Arif, Yasser S Amer, Maher A Titi, Mohammed O Al-Rukban
RATIONALE, AIMS AND OBJECTIVES: Type 2 diabetes mellitus (T2DM) is a worldwide and national public health problem that has a great impact on the population in Saudi Arabia. High-quality clinical practice guidelines (CPGs) are cornerstones in improving the health care provided for patients with diabetes. This study evaluated the methodological rigour, transparency, and applicability of recently published CPGs. METHODS: Our group conducted a systematic search for recently published CPGs for T2DM...
February 2018: Journal of Evaluation in Clinical Practice
https://read.qxmd.com/read/28934715/stercoral-perforation-of-the-rectosigmoid-colon-due-to-chronic-constipation-a-case-report
#15
Mustafa Fevzi Celayir, Hakan Mustafa Köksal, Mehmet Uludag
INTRODUCTION: Chronic constipation is very common in elderly patients. As a result of this situation fecaloma is also frequently seen at these ages. However, the stercoral perforation caused by fecaloma is a rare situation to occur. The rectosigmoid colon is the most affected colonic segment. It is seen in older patients with concomitant diseases and a low quality of life. PRESENTATION OF CASE: Here in this case, we have to report an 83 - year-old male patient who came to the emergency room with complaints of abdominal pain and constipation for two days...
2017: International Journal of Surgery Case Reports
https://read.qxmd.com/read/28914815/a-systematic-review-family-support-integrated-with-diabetes-self-management-among-uncontrolled-type-ii-diabetes-mellitus-patients
#16
REVIEW
Rian Adi Pamungkas, Kanittha Chamroonsawasdi, Paranee Vatanasomboon
The rate of type-2 diabetes mellitus (T2D) is dramatically increasing worldwide. Continuing diabetes mellitus (DM) care needs effective self-management education and support for both patients and family members. This study aimed to review and describe the impacts of diabetes mellitus self-management education (DSME) that involve family members on patient outcomes related to patient health behaviors and perceived self-efficacy on self-management such as medication adherence, blood glucose monitoring, diet and exercise changes, health outcomes including psychological well-being and self-efficacy, and physiological markers including body mass index, level of blood pressure, cholesterol level and glycemic control...
September 15, 2017: Behavioral Sciences
https://read.qxmd.com/read/28816537/evaluating-the-prescription-of-angiotensin-converting-enzyme-inhibitors-or-receptor-blockers-in-patients-with-diabetes-in-jordan
#17
Fadia Mayyas, Wa'ed Bataineh, Anan Jarab
OBJECTIVE: The angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) are guideline-recommended agents to prevent development and progression of nephropathy and cardiovascular diseases in diabetes mellitus (DM). The aim of this study was to evaluate the prescription of ACEIs/ARBs in DM patients with guideline indications. METHODS: Electronic data files for diabetes patients were retrospectively reviewed at a primary care setting northern Jordan...
November 2017: Endocrine Practice
https://read.qxmd.com/read/28446809/blood-pressure-management-in-patients-with-type-2-diabetes-mellitus
#18
REVIEW
Hisashi Kai
Hypertension aggravates macrovascular and microvascular diseases and mortality in patients with type 2 diabetes mellitus (T2DM). The current Japanese Society of Hypertension Guidelines of the Management of Hypertension (JSH 2014) recommends that antihypertensive medication should be initiated concomitantly with lifestyle modification when blood pressure (BP) is ⩾130/80 mm Hg and that target levels of office and home BP should be <130/80 mm Hg and <125/75 mm Hg, respectively, in T2DM patients...
August 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://read.qxmd.com/read/28440515/-interpretation-of-the-international-joint-statement-on-metabolic-surgery-in-the-treatment-algorithm-for-type-2-diabetes
#19
Peng Zhang, Chengzhu Zheng
Along with the soaring prevalence of obesity and type 2 diabetes mellitus (T2DM) globally, metabolic and bariatric surgery (MBS) has been rapidly developing into a major surgical subspecialty. However, the indications, benefits and potential risks of MBS are still controversial so far. In September 2015, the 2nd Diabetes Surgery Summit (DSS-II() was successfully convened, and later on an international joint statement on metabolic surgery in the treatment algorithm for T2DM was released based upon the consensus reached in DSS-II(, aiming to serve as a new global clinical guideline...
April 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/28102710/development-and-validation-of-a-uplc-ms-ms-method-for-simultaneous-determination-of-fotagliptin-and-its-two-major-metabolites-in-human-plasma-and-urine
#20
Zhenlei Wang, Ji Jiang, Pei Hu, Qian Zhao
AIM: Fotagliptin is a novel dipeptidyl peptidase IV inhibitor under clinical development for the treatment of Type II diabetes mellitus. The objective of this study was to develop and validate a specific and sensitive ultra-performance liquid chromatography (UPLC)-MS/MS method for simultaneous determination of fotagliptin and its two major metabolites in human plasma and urine. Methodology & results: After being pretreated using an automatized procedure, the plasma and urine samples were separated and detected using a UPLC-ESI-MS/MS method, which was validated following the international guidelines...
February 2017: Bioanalysis
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