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Abbreviated MRI

Jouko Miettunen, Marianne Haapea, Lassi Björnholm, Sanna Huhtaniska, Teija Juola, Lotta Kinnunen, Heli Lehtiniemi, Johannes Lieslehto, Nina Rautio, Tanja Nordström
The Northern Finland Birth Cohort 1986 is a large population-based birth cohort, which aims to promote health and wellbeing of the population. In this paper, we systematically review the psychiatric research performed in the cohort until today, i.e. at the age of 32 years of the cohort (2018). We conducted a systematic literature search using the databases of PubMed and Scopus and complemented it with a manual search. We found a total of 94 articles, which were classified as examining ADHD, emotional and behavioural problems, psychosis risk or other studies relating to psychiatric subjects...
December 2019: International Journal of Circumpolar Health
Styliani Giza, Eleni Litou, Eleni P Kotanidou, Angeliki N Kleisarchaki, Panagiotis Koliatos, Tasos Tzirtzipis, Vasiliki Rengina Tsinopoulou, Athanasios Tychalas, Athanasios Evangeliou, Assimina Galli-Tsinopoulou
Neuropathy, a complication of type 1 diabetes (T1D), is a heterogeneous group, and chronic polyneuropathy is the most common form in adults. Αn 8-year-old girl admitted with severe diabetic ketoacidosis was diagnosed with T1D. She was managed with intravenous fluids and insulin and was subsequently commenced on multiple daily subcutaneous injections of insulin. On the 7th day of hospitalisation, a right foot drop with sensory loss on the dorsal surface and cellulitis were detected and the latter responded to intravenous antibiotics...
February 11, 2019: Paediatrics and International Child Health
Samantha L Heller, Linda Moy
Contrast-enhanced breast MRI is a standard evidence-based component of supplemental screening in conjunction with mammography for higher-risk populations because of its high sensitivity for detecting breast cancer; the use of breast MRI for screening in high-risk populations is recommended in multiple national and international guidelines. The current MRI exam, however, is expensive relative to other screening technologies such as mammography, and relatively more time-intensive. Recent investigations have focused on techniques that have the potential for improving efficiency of the breast MRI exam, decreasing acquisition and reading times, without impacting diagnostic accuracy...
January 28, 2019: Journal of Magnetic Resonance Imaging: JMRI
Rossano Girometti, Lorenzo Cereser, Filippo Bonato, Chiara Zuiani
Multiparametric magnetic resonance imaging (mpMRI) has become the standard of care to achieve accurate and reproducible diagnosis of prostate cancer. However, mpMRI is quite demanding in terms of technical rigour, patient's tolerability and safety, expertise in interpretation, and costs. This paper reviews the main technical strategies proposed as less-is-better solutions for clinical practice (non-contrast biparametric MRI, reduction of acquisition time, abbreviated protocols, computer-aided diagnosis systems), discussing them in the light of the available evidence and of the concurrent evolution of Prostate Imaging Reporting and Data System (PI-RADS)...
January 28, 2019: European radiology experimental
Christiane K Kuhl
Given the increasing understanding of cancer as a heterogeneous group of diseases, detection methods should offer a sensitivity profile that ensures perfect sensitivity for biologically important cancers while screening out self-limiting pseudocancers. However, mammographic screening is biased toward detection of ductal carcinoma in situ and slowly growing cancers-and thus frequently fails to detect biologically aggressive cancers. This explains the persistently high rates of interval cancers and high rates of breast cancer mortality observed in spite of decades of mammographic screening...
January 27, 2019: Annual Review of Medicine
Ritse M Mann, Christiane K Kuhl, Linda Moy
Multiple studies in the first decade of the 21st century have established contrast-enhanced breast MRI as a screening modality for women with a hereditary or familial increased risk for the development of breast cancer. In recent studies, in women with various risk profiles, the sensitivity ranges between 81% and 100%, which is approximately twice as high as the sensitivity of mammography. The specificity increases in follow-up rounds to around 97%, with positive predictive values for biopsy in the same range as for mammography...
January 18, 2019: Journal of Magnetic Resonance Imaging: JMRI
Miriam Frenken, Christoph Schleich, Ralph Brinks, Daniel Benjamin Abrar, Christine Goertz, Matthias Schneider, Benedikt Ostendorf, Philipp Sewerin
BACKGROUND: The aim of the study was to evaluate a simplified version of the Rheumatoid Arthritis Magnetic Resonance Imaging Score (RAMRIS) for five joints of the hand (RAMRIS-5) in patients with early rheumatoid arthritis (RA) before and after the initiation of methotrexate (MTX) therapy using high-resolution, 3-T magnetic resonance imaging (MRI). METHODS: Twenty-eight patients with a seropositive, early RA (disease duration of less than 6 months (range 2-23 weeks)) according to 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) criteria (mean age 56...
January 14, 2019: Arthritis Research & Therapy
Xiaowei Song, Guanghai Yan, Songshi Quan, Enhao Jin, Jishan Quan, Guangyu Jin
To noninvasively monitor the effect of gene therapy and achieve an optimal therapeutic effect, liposomes encapsulated polyethylenimine (PEI)-coated superparamagnetic iron oxide nanoparticles (SPION) with dual functions of MRI diagnosis and gene therapy were prepared. SPION was synthesized via co-precipitation, and then modified with PEI via thiourea reaction. The liposomes encapsulating PEI-SPION (LP-PEI-SPION) were prepared by ethanol injection. Fourier transform infrared spectra confirmed that PEI was successfully modified onto SPION, and thermogravimetric analysis indicated that the PEI content was about 17...
December 25, 2018: Bioscience, Biotechnology, and Biochemistry
Akshay S Chaudhari, Kathryn J Stevens, Bragi Sveinsson, Jeff P Wood, Christopher F Beaulieu, Edwin H G Oei, Jarrett K Rosenberg, Feliks Kogan, Marcus T Alley, Garry E Gold, Brian A Hargreaves
BACKGROUND: Clinical knee MRI protocols require upwards of 15 minutes of scan time. PURPOSE/HYPOTHESIS: To compare the imaging appearance of knee abnormalities depicted with a 5-minute 3D double-echo in steady-state (DESS) sequence with separate echo images, with that of a routine clinical knee MRI protocol. A secondary goal was to compare the imaging appearance of knee abnormalities depicted with 5-minute DESS paired with a 2-minute coronal proton-density fat-saturated (PDFS) sequence...
December 23, 2018: Journal of Magnetic Resonance Imaging: JMRI
Ateeq Mubarik, Syed Moin Hassan, Monicka Felix, Salman Muddassir, Furqan Haq
Introduction: Sarcoidosis is an inflammatory granulomatous multisystem disease with an unknown etiology. Neurosarcoidosis is a cryptogenic neuroinflammatory manifestation of sarcoidosis. Case report: We describe a case of neurosarcoidosis with initial presentation as confusion. Our patient fits the picture of probable neurosarcoidosis as per the Zajicek et al criteria, with the clinical presentation of neurosarcoidosis, evidence of inflammation in the CNS, evidence of systemic sarcoidosis and exclusion of other diseases...
2018: Journal of Community Hospital Internal Medicine Perspectives
Yiming Gao, Elena F Brachtel, Osvaldo Hernandez, Samantha L Heller
Breast MRI is the most sensitive imaging modality for assessment of the nipple-areola complex (NAC), which is important both in cancer staging and in high-risk screening. However, the normal appearance of the nipple at MRI is not well defined because of a paucity of scientific literature on this topic. Hence, there is a lack of descriptive terminology and diagnostic criteria, which may account for the wide variability in interpretation among radiologists when assessing the NAC on MR images. In light of the current shift toward possible expanded use of abbreviated (ie, fast) breast MRI for screening in women at average risk for cancer in particular, and because an increasing number of women now undergo nipple-sparing mastectomy for therapeutic and/or prophylactic indications, careful assessment of the NAC at MRI is essential...
December 14, 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
Da Zhang, Zhixiong Cai, Naishun Liao, Shanyou Lan, Ming Wu, Haiyan Sun, Zuwu Wei, Juan Li, Xiaolong Liu
Although photothermal therapy (PTT) has become a compelling strategy for cancer therapy, few studies concern the physiological consequences of PTT ablation. Herein, we discover that PTT-induced hyperthermia can aggravate tumor hypoxia, which may increase the risk of tumor recurrence and reduce PTT efficacy. We thus integrated the pH/hypoxia-triggered Fe(iii)-banoxantrone (AQ4N) prodrug and semiconducting polymer dots (SPs) for programmable triggered cancer photothermal-chemotherapy. A SP-hybridized mesoporous silica framework, decorated by dopamine and polyethylene glycol, named PPMSF, was synthesized by a simple method, and then served as an efficient photo-absorbing agent (PTA) and drug carrier...
October 7, 2018: Chemical Science
A Muth, J Crona, O Gimm, A Elmgren, K Filipsson, M Stenmark Askmalm, J Sandstedt, M Tengvar, E Tham
Pheochromocytomas (PCC) and paragangliomas (PGL), collectively abbreviated PPGL are rare tumours originating from the chromaffin cells in the adrenal medulla (PCC) or the sympathetic or parasympathetic extra-adrenal paraganglia (PGL) (1, 2), Figure 1. The enlarged cell volume leads to increased levels of catecholamines (adrenaline, noraderenaline and/or dopamine) and their metabolites which can be measured in plasma or urine for biochemical diagnosis. Hormone-producing PPGL commonly originate from sympathetic paraganglia in the adrenal glands, abdomen or pelvis (3)...
December 8, 2018: Journal of Internal Medicine
Ali Keshavarzi, Vinod Kumar
The present work was designed to study the pH, sand, silt, clay, lime, organic carbon (OC), cation exchange capacity and heavy metals (Fe, Mn, Cu and Zn) in agricultural soils of Mashhad plain, Northeastern Iran. Pearson's correlation analysis showed that OC influenced the retention of Cu and Mn in both surface and subsurface agricultural soil samples. The results of contamination factor, pollution index and potential ecological risk (RI) indicated low pollution of Mn, Zn and Cu in the agricultural soil samples...
December 10, 2018: International Journal of Environmental Health Research
Zhen Kang, Xiangde Min, Jeffrey Weinreb, Qiubai Li, Zhaoyan Feng, Liang Wang
OBJECTIVE: The objective of our study was to evaluate the diagnostic accuracy of abbreviated biparametric MRI (bpMRI) versus standard multiparametric MRI (mpMRI) for prostate cancer (PCa) using guided biopsy or prostatectomy histopathology results as the reference standard. MATERIALS AND METHODS: A comprehensive literature search of PubMed, Web of Science, and Cochrane Library databases was performed by two researchers independently and the relevant references were assessed...
December 4, 2018: AJR. American Journal of Roentgenology
Heather I Greenwood
Breast MRI has been shown to be the most sensitive examination in the detection of breast cancer. However, given the high associated costs, its use in the screening setting has traditionally been limited to those who are at high-risk for breast cancer. Abbreviated protocol breast MRI is capable of reducing the traditional costs associated with breast MRI, while maintaining diagnostic accuracy and cancer detection, and therefore a potential future screening tool for breast cancer in a broader population of women than just those at high-risk...
January 2019: Clinical Imaging
Rossano Girometti, Adriana Nitti, Michele Lorenzon, Franco Greco, Viviana Londero, Chiara Zuiani
BACKGROUND: Previous studies have shown that abbreviated magnetic resonance imaging (aMRI) compares well to full-protocol MRI (fpMRI) in breast cancer (BC) screening, with the potential advantage of a less costly and complex examination. To our knowledge, the role for aMRI in staging BC has been poorly investigated, especially in assessing additional disease (ie, additional lesions compared to the index one prompting the examination). PURPOSE: To compare aMRI and fpMRI in detecting additional disease in BC staging...
October 22, 2018: Journal of Magnetic Resonance Imaging: JMRI
Katerina Deike-Hofmann, Franziska Koenig, Daniel Paech, Constantin Dreher, Stefan Delorme, Heinz-Peter Schlemmer, Sebastian Bickelhaupt
Oncologic imaging focused on the detection of breast cancer is of increasing importance, with over 1.7 million new cases detected each year worldwide. MRI of the breast has been described to be one of the most sensitive imaging modalities in breast cancer detection; however, clinical use is limited due to high costs. In the past, the objective and clinical routine of oncologic imaging was to provide one extended imaging protocol covering all potential needs and clinical implications regardless of the specific clinical indication or question...
October 16, 2018: Journal of Magnetic Resonance Imaging: JMRI
Luigi Mansi
No abstract text is available yet for this article.
October 11, 2018: European Journal of Nuclear Medicine and Molecular Imaging
Nicholas Seppala, Rashin Fallah Rastegar, Lara Richmond, Carrie Betel, Kalesha Hack, Mia Skarpathiotakis, Roberta Jong, Rebecca Thornhill, Belinda Curpen
BACKGROUND: In Canada, breast MRI has traditionally been reserved for evaluation of disease extent in patients with known breast malignancy. More recently, MRI has been emerging as an instrument for breast screening. However, its utilization is limited by increased relative cost and increased reader time. In this study, we evaluate a rapid MRI protocol for breast cancer screening within a breast screening population. METHODS: A series of 100 MRI studies performed in a high-risk breast cancer population were selected, ensuring a mix of malignant and benign pathology and normal cases...
September 27, 2018: Breast Journal
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