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Frug interactions

Xiao Wei, Yanhong Guo, Changlin Shao, Zhongke Sun, Daria Zhurina, Dawei Liu, Wei Liu, Dayang Zou, Zheng Jiang, Xuesong Wang, Jiangli Zhao, Wei Shang, Xuelian Li, Xiangru Liao, Liuyu Huang, Christian U Riedel, Jing Yuan
Recently, a putative ATP-binding cassette (ABC) transport system was identified in Bifidobacterium longum NCC2705 that is highly up-regulated during growth on fructose as the sole carbon source. Cloning and expression of the corresponding ORFs (bl0033-0036) result in efficient fructose uptake by bacteria. Sequence analysis reveals high similarity to typical ABC transport systems and suggests that these genes are organized as an operon. Expression of FruE is induced by fructose, ribose, or xylose and is able to bind these sugars with fructose as the preferred substrate...
January 2, 2012: Journal of Biological Chemistry
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