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Nutrition and Gestational Diabetes

Shaofang Lv, Shanlan Yu, Rongxiang Chi, Dongmei Wang
OBJECTIVES: To determine the effects of nutritional nursing intervention based on glycemic load (GL) for patients with gestational diabetes mellitus. MATERIAL AND METHODS: One hundred thirty-four patients diagnosed with gestational diabetes mellitus at our hospital were selected from March 2015 to March 2017 and randomly divided into the observation (n = 67) and control groups (n = 67). All of the patients in the observation and control groups received conventional nutritional nursing...
2019: Ginekologia Polska
Zamzam Paknahad, Atefeh Fallah, Amir Reza Moravejolahkami
Maternal nutritional status during pregnancy will affect the outcomes for the mother and the newborn. Maternal diet was assessed in 150 pregnant women during the first trimester of pregnancy by a 168-item food frequency questionnaire. Dietary patterns were explored by Factor analysis, and association of patterns with maternal and neonatal outcomes such as gestational diabetes mellitus (GDM), anemia and anthropometric indices were determined by analysis of variance and linear regression analysis. Three major dietary patterns were identified: 1) High Carbohydrate-Lower Fat (mean age, 27...
January 2019: Clinical Nutrition Research
Valentina Ponzo, Debora Fedele, Ilaria Goitre, Filomena Leone, Antonela Lezo, Clara Monzeglio, Concetta Finocchiaro, Ezio Ghigo, Simona Bo
Medical nutritional therapy is the first-line approach in managing gestational diabetes mellitus (GDM). Diet is also a powerful modulator of the gut microbiota, whose impact on insulin resistance and the inflammatory response in the host are well known. Changes in the gut microbiota composition have been described in pregnancies either before the onset of GDM or after its diagnosis. The possible modulation of the gut microbiota by dietary interventions in pregnancy is a topic of emerging interest, in consideration of the potential effects on maternal and consequently neonatal health...
February 3, 2019: Nutrients
Tatsuya Kondo, Miwa Nakamura, Junji Kawashima, Takeshi Matsumura, Takashi Ohba, Munekage Yamaguchi, Hidetaka Katabuchi, Eiichi Araki
Although hyperemesis gravidarum (HG), an extreme form of morning sickness, is a common complication during pregnancy, HG associated simultaneous onset of rhabdomyolysis and diabetes insipidus due to electrolyte abnormalities are rare. A 34-year-old woman with severe HG at 17 weeks of gestation complicated with appetite loss, weight reduction by 17 kg, general fatigue, myalgia, weakness and polyuria was identified to have simultaneous hypophosphatemia (1.6 mg/dL) and hypokalemia (2.0 mEq/L). Appetite recovery and the improvement of the hypophosphatemia (3...
January 29, 2019: Endocrine Journal
Louise J Maple-Brown, Greta Lindenmayer, Federica Barzi, Cherie Whitbread, Christine Connors, Elizabeth Moore, Jaqueline Boyle, Marie Kirkwood, I-Lynn Lee, Danielle Longmore, Paula Van Dokkum, Mary Wicks, Michelle Dowden, Chrissie Inglis, Margaret Cotter, Renae Kirkham, Sumaria Corpus, Sridhar Chitturi, Sujatha Thomas, Kerin O'dea, Paul Zimmet, Jeremy Oats, Harold D McIntyre, Alex Brown, Jonathan E Shaw
BACKGROUND: In Australia's Northern Territory, Indigenous mothers account for 33% of births and have high rates of hyperglycaemia in pregnancy. Prevalence of type 2 diabetes in pregnancy is up to 10 times higher in Indigenous than non-Indigenous Australian mothers, and the use of metformin is common. We assessed birth outcomes in relation to metformin use during pregnancy from a clinical register. METHODS: Women with gestational diabetes (GDM), newly diagnosed diabetes in pregnancy (DIP), or pre-existing type 2 diabetes (T2DM) from 2012 to 2016 were included...
January 25, 2019: Journal of Diabetes
Maura B Gentner, Mary L O'Connor Leppert
Scientific advances over the last century have generated compelling evidence of the primary and secondary effects of gestational, infant, and childhood conditions. These early environmental influences have the potential not only to impact an individual's health outcomes, such as heart disease, type 2 diabetes, and cancer, but also to confer various protections and risks to that individual's descendants. The immediate and extended ramifications of early environmental exposure bring an understanding of epidemiological impact on disease states and a hope for prevention...
January 22, 2019: Developmental Medicine and Child Neurology
Ioannis Kakoulidis, Ioannis Ilias, Anastasia Linardi, Charalampos Milionis, Aikaterini Michou, Eftychia Koukkou
AIM: Betamethasone's effect on glucose homeostasis in the presence of gestational diabetes has not been adequately investigated. MATERIALS-METHODS: We assessed the glycemic profile of 99 women with gestational diabetes (52 on insulin, 47 on medical nutrition therapy) who were given betamethasone during hospitalization for at risk pregnancies. RESULTS: In insulin-treated women the increase in total daily insulin dose significantly linked to betamethasone dose (p = 0...
January 2019: Diabetes & Metabolic Syndrome
Gwendolyn Patience Mensah, Dalena R M van Rooyen, Wilma Ten Ham-Baloyi
BACKGROUND: Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance that is observed in the beginning of, or first acknowledged during pregnancy. The prevalence of GDM is estimated to be approximately 15% globally and is expected to increase due to growing numbers of overweight and obesity in women in their reproductive age. The nursing management of GDM in terms of lifestyle modifications (exercise, diet and nutrition) and the taking of diabetes medication, if required, and adherence thereto is crucial to prevent maternal and neonatal-perinatal complications...
January 4, 2019: Midwifery
Bao-Hua Gou, Hui-Min Guan, Yan-Xia Bi, Bing-Jie Ding
BACKGROUND: Weight gain during pregnancy reflects the mother's nutritional status. However, it may be affected by nutritional therapy and exercise interventions used to control blood sugar in gestational diabetes mellitus (GDM). This study aimed to evaluate weight gain during gestation and pregnancy outcomes among women with GDM. METHODS: A retrospective study involving 1523 women with GDM was conducted between July 2013 and July 2016. Demographic data, gestational weight gain (GWG), blood glucose, glycated-hemoglobin level, and maternal and fetal outcomes were extracted from medical records...
January 3, 2019: Chinese Medical Journal
Bettina Utz, Bouchra Assarag, Tom Smekens, Hassan Ennassiri, Touria Lekhal, Nawal El Ansari, Bouchra Fakhir, Amina Barkat, Amina Essolbi, Vincent De Brouwere
BACKGROUND: Gestational Diabetes Mellitus (GDM) testing and management in Morocco is associated with delays resulting in late commencement of treatment. To reduce delays and to increase access of women to GDM care, a country-adapted intervention targeting primary health care providers was designed to test the hypothesis that detection and initial management of GDM at the primary level of care improves newborn outcomes in terms of lower birthweights and less cases of macrosomia and impacts on maternal weight gain, glucose balance and pregnancy outcomes...
2018: PloS One
Veronica Falcone, Tina Stopp, Michael Feichtinger, Herbert Kiss, Wolfgang Eppel, Peter Wolf Husslein, Gerhard Prager, Christian S Göbl
Bariatric surgery (BS) is regarded to be the most effective treatment of obesity with long lasting beneficial effects including weight loss and improvement of metabolic disorders. A considerable number of women undergoing BS are at childbearing age.Although the surgery mediated weight loss has a positive effect on pregnancy outcome, the procedures might be associated with adverse outcomes as well, for example micronutrient deficiencies, iron or B12 deficiency anemia, dumping syndrome, surgical complications such as internal hernias, and small for gestational age (SGA) offspring, possibly due to maternal undernutrition...
December 27, 2018: BMC Pregnancy and Childbirth
Jessica Breuing, Dawid Pieper, Annika Lena Neuhaus, Simone Heß, Lena Lütkemeier, Fabiola Haas, Mark Spiller, Christine Graf
BACKGROUND: There is a significant worldwide increase in type 2 diabetes mellitus and gestational diabetes (T2DM/GDM) linked to a range of associated comorbidities and rising healthcare costs. It has been shown that an increase in physical activity, healthy nutrition, and weight loss may prevent or delay T2DM/GDM manifestation. Despite this, it remains a key challenge to reach various populations, in particular so-called vulnerable groups, mostly with a migration background and/or low socio-economic status...
December 23, 2018: Systematic Reviews
Maisa N Feghali, Kaleab Z Abebe, Diane M Comer, Steve Caritis, Janet M Catov, Christina M Scifres
OBJECTIVE:  We assessed if the initial response to medical nutritional therapy (MNT) can help predict the need for pharmacological therapy in women with gestational diabetes mellitus (GDM). METHODS:  We identified 1,174 women with GDM who underwent standardized dietary counseling and reported glucose values from the first week of MNT. We compared women who required pharmacological therapy with those who did not use bivariate statistics, and used multivariable logistic regression modeling to assess for factors predicting the need for pharmacological therapy...
December 21, 2018: American Journal of Perinatology
Aleksandra Kozlowska, Anna Maja Jagielska, Katarzyna Malgorzata Okreglicka, Filip Dabrowski, Krzysztof Kanecki, Aneta Nitsch-Osuch, Miroslaw Wielgos, Dorota Bomba-Opon
OBJECTIVES: Maintaining proper nutrition during pregnancy is crucial for pregnant women and especially for who have been diagnosed with type 1 diabetes mellitus (T1DM) or who develop gestational diabetes mellitus (GDM). MATERIAL AND METHODS: To measure differences in vitamin and mineral intakes among women with normal pregnancies, pregnant women with GDM, and pregnant women with pre-gestational T1DM; and to assess the women's dietary intakes in comparison with Polish nutritional guidelines...
2018: Ginekologia Polska
Rosette J Chakkalakal, Amber J Hackstadt, Ricardo Trochez, Rebecca Gregory, Tom A Elasy
BACKGROUND: Women diagnosed with gestational diabetes mellitus (GDM) substantially modify their diets during pregnancy to control hyperglycemia. These changes could also affect maternal weight management. MATERIALS AND METHODS: From July 2014 to December 2015 we enrolled women with and without GDM in a prospective cohort study to compare their mean rates of (1) weight gain before GDM screening, (2) weight gain after GDM screening, and (3) postpartum weight loss...
November 17, 2018: Journal of Women's Health
Carla Assaf-Balut, Nuria Garcia de la Torre, Alejandra Durán, Manuel Fuentes, Elena Bordiú, Laura Del Valle, Johanna Valerio, Cristina Familiar, Inés Jiménez, Miguel Angel Herraiz, Nuria Izquierdo, Maria José Torrejón, Isabelle Runkle, Maria Paz de Miguel, Inmaculada Moraga, Maria Carmen Montañez, Ana Barabash, Martín Cuesta, Miguel A Rubio, Alfonso Luis Calle-Pascual
Objectives: To assess whether Mediterranean Diet (MedDiet)-based medical nutrition therapy facilitates near-normoglycemia in women with gestational diabetes mellitus (GDMw) and observe the effects on adverse pregnancy outcomes. Research design and methods: This is a secondary analysis of the St Carlos GDM Prevention Study, conducted between January and December 2015 in Hospital Clínico San Carlos (Madrid, Spain). One thousand consecutive women with normoglycemia were included before 12 gestational weeks (GWs), with 874 included in the final analysis...
2018: BMJ Open Diabetes Research & Care
Xinting Yu, Shi Song Rong, Xiujing Sun, Guofang Ding, Weilin Wan, Liying Zou, Shaowen Wu, Ming Li, Danhua Wang
Breast milk (BM) hormones have been hypothesised as a nutritional link between maternal and infant metabolic health. This study aimed to evaluate hormone concentrations in BM of women with and without gestational diabetes mellitus (GDM), and the relationship between maternal factors, BM hormones and infant growth. We studied ninety-six nulliparous women with (n 48) and without GDM and their exclusively breastfed term singletons. Women with GDM received dietary therapy or insulin injection for euglycaemia during pregnancy...
December 2018: British Journal of Nutrition
Fei Gao, Huabin Luo, Katherine Jones, Wanda Nicholson, Ronny A Bell
INTRODUCTION: Women with gestational diabetes are at 7 times greater risk of developing type 2 diabetes than are women without gestational diabetes. The objectives of this study were to examine recent changes in the prevalence of gestational diabetes mellitus among women of reproductive age in the United States and assess the prevalence of factors associated with participating in healthy lifestyle behaviors. METHODS: Data were from 4 waves of the National Health and Nutrition Examination Survey (2007-2014)...
October 25, 2018: Preventing Chronic Disease
Katrien Benhalima, Caro Minschart, Dries Ceulemans, Annick Bogaerts, Bart Van Der Schueren, Chantal Mathieu, Roland Devlieger
Gestational diabetes mellitus (GDM) is a frequent medical complication during pregnancy. This is partly due to the increasing prevalence of obesity in women of childbearing age. Since bariatric surgery is currently the most successful way to achieve maintained weight loss, increasing numbers of obese women of childbearing age receive bariatric surgery. Bariatric surgery performed before pregnancy significantly reduces the risk to develop GDM but the risk is generally still higher compared to normal weight pregnant women...
October 11, 2018: Nutrients
Taofeek O Usman, Emmanuel D Areola, Olufunto O Badmus, InKyeom Kim, Lawrence A Olatunji
Nutritional challenges and androgen excess have been implicated in the development of gestational diabetes and poor fetal outcome, but the mechanisms are not well delineated. The effects of short chain fatty acid (SCFA) on glucose dysmetabolism and poor fetal outcome induced by gestational androgen excess is also not known. We tested the hypothesis that blockade of androgen receptor (AR) and suppression of late gestational androgen excess prevents glucose dysmetabolism and poor fetal outcome through suppression of adenosine deaminase (ADA)/xanthine oxidase (XO) pathway...
September 5, 2018: Journal of Nutritional Biochemistry
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