keyword
https://read.qxmd.com/read/38531788/rare-but-still-there-a-scoping-review-on-endometriosis-associated-ovarian-cancer
#1
JOURNAL ARTICLE
Karl Livori, Jean Calleja-Agius
Endometriosis is a medical condition affecting at least up to 10% of women of reproductive age. This condition occurs when ectopic endometrial glands and stroma implant outside the uterus and there are several theories regarding the underlying origins of the disease. Endometriosis is one of the major causes of severe dysmenorrhoea, chronic pelvic pain and infertility. While endometriosis is generally a non-malignant condition, it rarely may transform into an invasive cancer, and increase the risk for epithelial ovarian cancer, notably endometrioid or clear cell ovarian cancer...
March 2024: Discovery Medicine
https://read.qxmd.com/read/38531608/human-endometrium-derived-mesenchymal-stem-cells-with-aberrant-nod1-expression-are-associated-with-ectopic-endometrial-lesion-formation
#2
JOURNAL ARTICLE
Chunmei Li, Suiyu Luo, Ai Guo, Ying Su, Yuhui Zhang, Yan Song, Mei Liu, Lu Wang, Yuanyuan Zhang
Nucleotide-binding oligomerization domain 1 (NOD1), a cytosolic pattern recognition receptor protein, plays a crucial role in innate immune responses. However, the functional expression of NOD1 in mesenchymal stem cells (MSCs) derived from endometriosis remains unclear. The aim of this study was to explore the functions of NOD1 in ectopic endometrial lesions. Tissues and MSCs were isolated from both normal endometrium and endometriosis. Immunohistochemistry and real time quantitative polymerase chain reaction (RT-qPCR) were used to determine the expression of NOD1 in the tissues/MSCs...
March 27, 2024: International Journal of Stem Cells
https://read.qxmd.com/read/38531540/endometriosis-associated-ovarian-cancer-a-different-clinical-entity
#3
JOURNAL ARTICLE
Umberto Leone Roberti Maggiore, G Bogani, Biagio Paolini, Fabio Martinelli, Giulia Chiarello, Ludovica Spanò Bascio, Valentina Chiappa, Simone Ferrero, Antonino Ditto, Francesco Raspagliesi
OBJECTIVE: To compare survival outcomes and patterns of recurrence between endometriosis-associated ovarian cancer patients and non-endometriosis-associated ovarian cancer patients. METHODS: This retrospective study included data of consecutive patients with endometrioid or clear cell ovarian cancer treated at the Fondazione IRCCS Istituto Nazionale dei Tumori di Milano between January 2010 and June 2021. Patients were assigned to one of two groups according to the absence or presence of endometriosis together with ovarian cancer at final histological examination...
March 25, 2024: International Journal of Gynecological Cancer
https://read.qxmd.com/read/38531006/postmenopausal-endometriosis-a-challenging-condition-beyond-menopause
#4
JOURNAL ARTICLE
Alexandre Vallée, Marie Carbonnel, Pierre-François Ceccaldi, Anis Feki, Jean-Marc Ayoubi
IMPORTANCE AND OBJECTIVE: Postmenopausal endometriosis is a complex condition that challenges the conventional belief that endometriosis resolves with menopause. Despite the cessation of menstruation, a subset of women continues to experience or develop endometriosis-related symptoms during the postmenopausal period. Thus, this review aimed to shed light on postmenopausal endometriosis, exploring its clinical features, diagnostic considerations, management approaches, and the potential impact on women's health...
March 25, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38530759/proposed-classification-of-adenomyosis-in-infertile-women-to-simplify-management-options-undergoing-art
#5
EDITORIAL
Sunita Tandulwadkar, Sneha Mishra, Swapnil Langde, Mily Pandey, Rashmika Gandhi
OBJECTIVE: Adenomyosis associated with subfertility is a situation of a dilemma for the treating clinician as the treatment is highly controversial and there remains an overall lack of consensus regarding the value of conservative surgery with or without medical management to improve reproductive out-comes. Hence we proposed this classification based on mapping of the size of adenomyoma, its location, distance from the endometrial cavity, and any associated endometriosis by studying 100 women with adenomyosis undergoing IVF...
March 26, 2024: JBRA Assisted Reproduction
https://read.qxmd.com/read/38528142/intramuscular-endometriosis-of-the-forearm-a-case-report
#6
JOURNAL ARTICLE
Kira L Smith, Lulu He, Julie Adhya, Lisa Ercolano
Endometriosis is a disorder that commonly affects females of reproductive age and is defined as the presence of endometrial glands or stroma outside the uterine cavity. Patients typically present with cyclical pain during menses. Endometriosis can be characterized as endopelvic or extrapelvic depending on the sites involved. We report a case of a 40-year-old, right-hand-dominant, female who presented with a painful mass in her right proximal forearm. She was ultimately diagnosed with intramuscular endometriosis and underwent surgical excision...
March 26, 2024: Skeletal Radiology
https://read.qxmd.com/read/38526611/correction-endometriosis-mr-mimickers-t2-hypointense-lesions
#7
Edouard Ruaux, Wendaline M VanBuren, Stéphanie Nougaret, Marie Gavrel, Mathilde Charlot, Flavia Grangeon, Pierre-Adrien Bolze, Isabelle Thomassin-Naggara, Pascal Rousset
No abstract text is available yet for this article.
March 25, 2024: Insights Into Imaging
https://read.qxmd.com/read/38525712/diagnostic-and-therapeutic-challenges-of-oligosymptomatic-vesicovaginal-fistula-in-the-complex-case-of-endometriosis
#8
Agnieszka A Strojny, Arkadiusz Baran, Katarzyna Wiejak, Anna Scholz, Radosław B Maksym
Endometriosis is a complex condition causing surgical challenges, sometimes leading to urogynecological complications, the diagnosis and treatment of which are not always obvious. We present a case of a 46-year-old woman with a history of severe endometriosis and adenomyosis who developed an oligosymptomatic vesicovaginal fistula (VVF) as a complication of surgery. The patient's medical history included multiple surgeries for endometriosis, a cesarean section, and a laparoscopic hysterectomy. After the excision of the full-thickness infiltration of the urinary bladder, she experienced postoperative bowel obstruction treated by laparotomy...
March 12, 2024: Clinics and Practice
https://read.qxmd.com/read/38524912/a-systematic-review-of-epigenetics-of-endometriosis
#9
JOURNAL ARTICLE
Bronwyn S Bedrick, Laura Courtright, Jiahui Zhang, Morgan Snow, Isabela Landsteiner Sampaio Amendola, Elisabeth Nylander, Kamaria Cayton-Vaught, James Segars, Bhuchitra Singh
OBJECTIVE: To assess the current literature evaluating the epigenetics of endometriosis in humans. EVIDENCE REVIEW: A systematic review was conducted in accordance with the PRISMA guidelines within PubMed, EBSCOhost, Cochrane Library, Embase, Scopus, and Web of Science Core Collection. A comprehensive search strategy was developed by a data informationist. Observational and interventional studies assessing epigenetics in humans published in English up to January 15th, 2023, were included...
January 2024: F&S reviews
https://read.qxmd.com/read/38524269/acupuncture-for-pain-and-pain-related-disability-in-deep-infiltrating-endometriosis
#10
JOURNAL ARTICLE
Giulia Chiarle, Gianni Allais, Silvia Sinigaglia, Gisella Airola, Sara Rolando, Fabiola Bergandi, Salvatore Micalef, Chiara Benedetto
OBJECTIVES: To evaluate the efficacy of acupuncture in relieving symptoms (dysmenorrhea, dyspareunia, pelvic pain and dyschezia) intensity, improving functional disability, reducing the number of days per months of dysmenorrhea, the frequency and the efficacy of analgesic use in deep infiltrating endometriosis (DIE). The safety profile was also evaluated. METHODS: The study sample was 34 patients with DIE; for 2 months (T-2, T-1) the women recorded diary notes on the numbers of days of menstruation, the presence, intensity, and disability related to dysmenorrhea, dyspareunia, pelvic pain, and dyschezia...
2024: Front Pain Res (Lausanne)
https://read.qxmd.com/read/38524095/laparoscopic-correction-of-isthmocele-and-cesarean-scar-endometriosis-a-report-of-a-successful-pregnancy-and-treatment-of-subfertility
#11
Jijisha Ali, Gazala Khan, Yevginiy Karamurzin, Rida Maryum, Sami Talo
We present a case of subfertility due to isthmocele and cesarean scar endometriosis with a successful pregnancy following laparoscopic repair. This case report is of a 35-year-old female (para 1, living 1) who presented to the gynecological outpatient department with complaints of lower abdominal pain, irregular vaginal bleeding for three months, and subfertility. She was suspected to have isthmocele and endometriosis at the site of the cesarean scar with seroma formation. She underwent a hysteroscopy and laparoscopic excision of the cyst at the site of the cesarean scar with the repair of the cesarean scar defect...
February 2024: Curēus
https://read.qxmd.com/read/38523535/readmission-following-methotrexate-treatment-for-tubal-pregnancy
#12
JOURNAL ARTICLE
Yossi Bart, Noam Regev, Uria Shani, Bracha Cohen, Fayrooz Yossef, Nadine Margieh, Nir Kugelman
OBJECTIVE: To identify risk factors for readmission following methotrexate treatment for tubal pregnancy. METHODS: A retrospective study undertaken in two tertiary medical centers, including all individuals with medically treated tubal pregnancy (N = 511), between December 2009 and June 2021. Individuals with and without readmission following methotrexate treatment were compared. The primary outcome was the readmission rate. Secondary outcomes included the rate of post-discharge gynecological emergency department visits, tubal rupture rate, and the eventual need for surgical treatment...
March 25, 2024: International Journal of Gynaecology and Obstetrics
https://read.qxmd.com/read/38522332/the-malignant-transformation-of-endometriosis-is-there-a-left-lateral-predisposition-of-ovarian-clear-cell-and-endometrioid-carcinomas
#13
JOURNAL ARTICLE
J Courtney McMullan, Michael J Graham, Elaine F Craig, W Glenn McCluggage, David H Hunter, Laura Feeney
INTRODUCTION: Endometriosis affects 10% of women of reproductive age. There is evidence for a left lateral predisposition of endometriotic lesions and a 1.9-fold greater risk of ovarian cancer in endometriosis. The aim of this study is to determine whether a left lateral predisposition of ovarian clear-cell carcinoma (CCC) and endometrioid carcinoma (EC) exists. MATERIALS AND METHODS: A retrospective cohort study of all EC and CCC patients in Northern Ireland between March-2011 and June-2018...
March 6, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38520099/-impact-of-the-microbiota-in-endometriosis-sensitivity
#14
JOURNAL ARTICLE
Nastia Colin-Laignelet, Daniel Vaiman
No abstract text is available yet for this article.
March 2024: Médecine Sciences: M/S
https://read.qxmd.com/read/38518487/pure-vs-mixed-clear-cell-ovarian-carcinomas-is-there-any-impact-on-survival
#15
JOURNAL ARTICLE
Duygu Güzel, Coşan Terek, Ayşegül Besler, Gürdeniz Serin, Züleyha Önal, Levent Akman, Erdem Göker, Ulus Ali Şanli, Osman Zekioğlu, Necmettin Özdemir, Aydın Özsaran, Nuri Yildirim
OBJECTIVE: Our primary aim in this study is to define the clinical characteristics of patients with clear-cell ovarian carcinoma and evaluate the prognostic factors affecting survival. STUDY DESIGN: Records of 85 patients, operated between 2000 and 2018, for an adnexal mass and whose final pathology reported clear cell ovarian carcinoma were reviewed. The study considered demographic data, clinical characteristics of the patients, as well as pure and mixed-type clear cell histology...
March 18, 2024: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/38518021/a-large-scale-causal-analysis-of-gut-microbiota-and-endometriosis-associated-infertility-a-mendelian-randomization-study
#16
JOURNAL ARTICLE
Yan Wang, Wangshu Li, Chunfang Ha
Endometriosis is a prevalent condition with notable impacts on fertility. Recent studies have implicated gut microbiota in the development of endometriosis associated infertility (EAI). This study employs Mendelian randomization (MR) to elucidate the causal relationship between specific gut microbes and EAI. Using MR, we selected single nucleotide polymorphisms associated with 211 gut microbiota taxa from large-scale genome-wide association studies summary data. We applied statistical methods including inverse variance weighting, weighted median, and MR-Egger for analysis...
March 22, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38515854/dienogest-in-conjunction-with-gnrh-a-for-postoperative-management-of-endometriosis
#17
JOURNAL ARTICLE
Ying Ma, Wen-Xin Wang, Ye Zhao
Objective: The aim of this study is to assess the postoperative efficacy of the combined administration of dienogest (DNG) and gonadotropin-releasing hormone agonists (GnRH-a) in patients diagnosed with endometriosis (EMS), while acknowledging the extensive use of DNG in the extended therapeutic management of EMS. Methods: In this retrospective study, a cohort of 154 patients who underwent conservative surgical intervention for EMS were scrutinized. The cohort was stratified into two distinct groups based on their prescribed pharmacological regimens...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38515672/diagnostic-accuracy-of-interleukin-6-in-multiple-diseases-an-umbrella-review-of-meta-analyses
#18
REVIEW
Zeyu Han, Jin Li, Xianyanling Yi, Tianyi Zhang, Dazhou Liao, Jia You, Jianzhong Ai
OBJECTIVE: This review aims to conduct a comprehensive study of the diagnostic accuracy of interleukin-6 (IL-6) for multiple diseases by utilizing existing systematic reviews and meta-analyses. METHODS: We performed a thorough search of Embase, Web of Science, PubMed, and Cochrane Database of Systematic Reviews up to April 2023 to gather meta-analyses that investigate the diagnostic accuracy of IL-6. To assess the methodological quality of the studies, we employed the Assessing the Methodological Quality of Systematic Reviews-2 and Grading of Recommendations, Assessment, Development and Evaluation criteria...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38514357/ultrasound-guided-erector-spinae-nerve-block-for-relief-of-endometriosis-pain-in-the-emergency-department
#19
Robert Stenberg, Kristen Septaric, Erin L Simon
Endometriosis is a debilitating chronic condition often accompanied by severe pelvic pain and infertility issues. When outpatient medical management is not adequate, controlling pain can be challenging for providers in the acute setting. We report the case of a 23-year-old female with a past medical history of endometriosis who presented to a freestanding emergency department with a chief complaint of 10/10 pelvic pain on a numeric rating scale. She had tried non-steroidal inflammatory medications and heat with no success...
March 15, 2024: American Journal of Emergency Medicine
https://read.qxmd.com/read/38513981/endometriosis-is-associated-with-higher-healthcare-utilization-and-upper-gastrointestinal-symptoms
#20
JOURNAL ARTICLE
Madison Simons, Michael Cline, Ashley Gubbels, Cara King, Anthony Lembo, Stephen Lupe
No abstract text is available yet for this article.
March 19, 2024: Clinical Gastroenterology and Hepatology
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