Gabriela Petrișor, Ludmila Motelica, Roxana Doina Trușcǎ, Andreea-Luiza Mȋrț, Gabriel Vasilievici, Justinian-Andrei Tomescu, Cristina Manea, Andreea Ștefania Dumbravǎ, Viorica Maria Corbu, Irina Gheorghe-Barbu, Denisa Ficai, Ovidiu-Cristian Oprea, Bogdan-Ștefan Vasile, Anton Ficai, Anca Daniela Raiciu
Melissa officinalis is an important medicinal plant that is used and studied intensively due to its numerous pharmacological effects. This plant has numerous active compounds with biomedical potential; some are volatile, while others are sensitive to heat or oxygen. Therefore, to increase stability and prolong biological activities, the natural extract can be loaded into various nanostructured systems. In this study, different loading systems were obtained from mesoporous silica, like Mobile Composition of Matter family (MCM) with a hexagonal (MCM-41) or cubic (MCM-48) pore structure, simple or functionalized with amino groups (using 3-aminopropyl) such as triethoxysilane (APTES)...
April 10, 2024: Pharmaceutics