Ganna Isayeva, Eliska Potlukova, Klara Rumora, Pedro Lopez Ayala, Atakan Kurun, Jan-Philipp Leibfarth, Ibrahim Schäfer, Evita Michel, Kaan Pesen, Michael J Zellweger, Marten Trendelenburg, Trine Korsgaard Hejlesen, Annette Gudmann Hansen, Steffen Thiel, Christian Mueller
BACKGROUND: We aimed to test the diagnostic and prognostic ability of H-ficolin, an initiator of the lectin pathway of the complement system, for functionally relevant coronary artery disease (fCAD), and explore its determinants. METHODS: The presence of fCAD was adjudicated using myocardial perfusion imaging single-photon emission tomography and coronary angiography. H-ficolin levels were measured by a sandwich-type immunoassay at rest, peak stress-test, and 2h after stress-test...
October 4, 2023: Clinica Chimica Acta; International Journal of Clinical Chemistry