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https://read.qxmd.com/read/33008782/analysis-of-the-symptomatology-disease-course-and-treatment-of-postorgasmic-illness-syndrome-in-a-large-sample
#1
Caleb Natale, Andrew Gabrielson, Hoang Minh Tue Nguyen, Brian Dick, Wayne J G Hellstrom
BACKGROUND: Postorgasmic illness syndrome (POIS) is a rare syndrome of unknown etiology where patients experience distressing physical and psychological after ejaculatory sequelae. AIM: To better characterize the epidemiology, symptomatology, disease course, and treatment of POIS, with specific interest placed on examining relationships between disease presentation and measures of disease burden. METHODS: A 30-item questionnaire was distributed to an online community of patients with POIS from June 2019 to January 2020...
September 30, 2020: Journal of Sexual Medicine
https://read.qxmd.com/read/31878818/postorgasmic-illness-syndrome-potential-new-treatment-options-for-a-rare-disorder
#2
Hudson Pierce, Jonathan Fainberg, Christopher Gaffney, Ahmad Aboukhashaba, Aleem Khan, James Kashanian
No abstract text is available yet for this article.
December 27, 2019: Scandinavian Journal of Urology
https://read.qxmd.com/read/31508233/post-orgasmic-illness-syndrome-what-do-we-know-till-now
#3
Maher Abdessater, Sandra Elias, Elie Mikhael, Abdalla Alhammadi, Sebastien Beley
Background: Peri orgasmic dysfunctions are very rare and little information exists on their diagnosis and treatment. One of these conditions is post-orgasmic illness syndrome (POIS), manifesting by a debilitating cluster of symptoms affecting men within seconds, minutes, or hours after ejaculation. The aim of this article is to do a thorough literature review about POIS, in order to elucidate the pathophysiology, the diagnosis and the management of this rare disease. Results: Updated literature review on Pubmed was done, using the following terms: "orgasm illness", "post-orgasmic" and "postorgasmic illness syndrome"...
2019: Basic and Clinical Andrology
https://read.qxmd.com/read/31399707/editorial-comment-on-first-assessment-of-the-validity-of-the-only-diagnostic-criteria-for-postorgasmic-illness-syndrome-pois
#4
Ahmet Tevfik Albayrak, Ege Can Serefoglu
No abstract text is available yet for this article.
August 9, 2019: International Journal of Impotence Research
https://read.qxmd.com/read/31171851/first-assessment-of-the-validity-of-the-only-diagnostic-criteria-for-postorgasmic-illness-syndrome-pois
#5
Alex Strashny
Postorgasmic illness syndrome (POIS) is a rare condition that affects men and about which little is known. According to Waldinger and colleagues, men with POIS fulfill three or more of five preliminary diagnostic criteria regarding symptoms, time to onset, setting, duration, and spontaneous disappearance. We conducted a self-report study to assess, for the first time, the validity of these criteria. One hundred and twenty-seven men with self-reported POIS have completed the survey, making this the largest study of such men to date...
June 6, 2019: International Journal of Impotence Research
https://read.qxmd.com/read/30063023/negative-allergy-study-in-a-case-of-postorgasmic-illness-syndrome-pois
#6
Nathalie Depreux, Maria Basagaña, Mariona Pascal
Postorgasmic illness syndrome (POIS) is a rarely described syndrome characterized by transient flu-like symptoms and cognition disorders. Recent studies suggest that immunogenic reactivity to autologous semen is the underlying mechanism in POIS. Our study is regarding a 30-year-old that visited our unit for an allergy consultation because he experienced malaise after ejaculations. Skin prick tests and intracutaneous tests with autologous diluted semen with negative results were performed. Immunoblotting and western blot of the patient's autologous semen showed negative results...
January 2018: Revista Internacional de Andrología
https://read.qxmd.com/read/26921646/contemporary-management-of-disorders-of-male-orgasm-and-ejaculation
#7
REVIEW
Stanley E Althof, Chris G McMahon
Ejaculatory disorders lie along a conceptual continuum with premature ejaculation anchoring one end, normal ejaculation in the center, and difficulties with delayed or anejaculation at the opposite end. Retrograde ejaculation, painful ejaculation, and postorgasmic illness syndrome can occur at any point on the continuum. This manuscript defines the ejaculatory dysfunctions, reviews the anatomy and physiology of orgasm and ejaculation, and summarizes the pharmacological, psychological, and combined treatment approaches to ejaculatory dysfunctions...
July 2016: Urology
https://read.qxmd.com/read/25630453/postorgasmic-illness-syndrome-pois-in-a-chinese-man-no-proof-for-ige-mediated-allergy-to-semen
#8
Nannan Jiang, Guangpeng Xi, Hongjun Li, Jia Yin
INTRODUCTION: Postorgasmic illness syndrome (POIS) is a rarely described syndrome characterized by transient flu-like symptoms and cognition disorders. Recent studies suggest that immunogenic reactivity to autologous semen is the underlying mechanism in POIS. However, there are no data published on immunoglobulin E (IgE)-mediated allergy to autologous semen in men without POIS. AIM: The purpose of the current work was to characterize the first diagnosed POIS patient in China and to study the allergic response of autologous semen in the affected patient and in three healthy males...
March 2015: Journal of Sexual Medicine
https://read.qxmd.com/read/21513019/postorgasmic-illness-syndrome
#9
COMMENT
Suzanne J Farley
No abstract text is available yet for this article.
March 2011: Nature Reviews. Urology
https://read.qxmd.com/read/21241454/hyposensitization-therapy-with-autologous-semen-in-two-dutch-caucasian-males-beneficial-effects-in-postorgasmic-illness-syndrome-pois-part-2
#10
Marcel D Waldinger, Marcus M H M Meinardi, Dave H Schweitzer
INTRODUCTION: Postorgasmic illness syndrome (POIS) is a post-ejaculatory complex of local and/or systemic symptoms that nearly always occurs within seconds, minutes, or hours post-masturbation, coitus, or spontaneous ejaculation. Recent data suggest an autoimmunogenic/allergic underlying mechanism. AIM: To treat males with POIS by hyposensitization with their own semen (autologous semen). METHODS: Two males suffering from POIS, of which one male with coincidental lifelong premature ejaculation (PE) were investigated...
April 2011: Journal of Sexual Medicine
https://read.qxmd.com/read/21241453/postorgasmic-illness-syndrome-pois-in-45-dutch-caucasian-males-clinical-characteristics-and-evidence-for-an-immunogenic-pathogenesis-part-1
#11
Marcel D Waldinger, Marcus M H M Meinardi, Aeilko H Zwinderman, Dave H Schweitzer
INTRODUCTION: Postorgasmic illness syndrome (POIS) is a combination of local allergic symptoms and transient flu-like illness. In this study, the investigators propose five preliminary criteria to establish the diagnosis. AIM: To describe the clinical details in 45 males being suspected of having POIS and to test an immunogenic hypothesis as the underlying mechanism of their presentations. METHODS: Forty-five males were studied according to standardized protocol, including neuropsychiatric and medical sexological evaluations; their complaints were categorized using their own words, and their self-perceived intravaginal ejaculation latency time (IELT)...
April 2011: Journal of Sexual Medicine
https://read.qxmd.com/read/20214722/postorgasm-illness-syndrome-a-spectrum-of-illnesses
#12
Jane Ashby, David Goldmeier
INTRODUCTION: We describe two men with marked symptoms following orgasm. In each case, the symptoms were consistent with those found in postorgasm illness syndrome (POIS). AIM: Further elucidation of the cause of the patients' symptoms. METHODS: Both cases were investigated for causes of POIS with biochemical, hormonal, neurological, autonomic, cardiological, and psychological workup. RESULTS: Extensive investigation did not reveal a major organic cause for these patients' symptoms...
May 2010: Journal of Sexual Medicine
https://read.qxmd.com/read/11995603/postorgasmic-illness-syndrome-two-cases
#13
Marcel D Waldinger, Dave H Schweitzer
We describe the symptoms of a postejaculatory syndrome in two men with spontaneous ejaculations. The syndrome consists of severe fatigue, intense warmth, and a flulike state, with generalized myalgia. These symptoms occur rapidly after ejaculation and only disappear after 4 to 7 days. The symptoms are so severe that sexual activity is avoided. The cluster of symptoms is named postorgasmic illness syndrome (POIS). To date, no explanation has been offered for the etiology and pathogenesis of the symptoms, and the prevalence is unknown...
May 2002: Journal of Sex & Marital Therapy
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