Christopher P Bellaire, Alex Devarajan, James G Napoli, John W Rutland, Helen Liu, Laya Jacob, Max Mandelbaum, Farah Sayegh, Ilana G Margulies, Pedram Goel, Bradley N Delman, Mark M Urata, Peter J Taub
BACKGROUND: Unilateral coronal craniosynostosis (UCS) is a congenital disorder resulting from the premature suture fusion, leading to complex primary and compensatory morphologic changes in the shape of not only the calvarium and but also into the skull base. This deformity typically requires surgery to correct the shape of the skull and prevent neurologic sequelae, including increased intracranial pressure, sensory deficits, and cognitive impairment. METHODS: The present multicenter study sought to reverse-engineer the bone dysmorphogenesis seen in non-syndromic UCS using a geometric morphometric approach...
September 1, 2022: Journal of Craniofacial Surgery