Nicholas C Harvey, John A Kanis, Enwu Liu, Cyrus Cooper, Mattias Lorentzon, Jennifer W Bea, Laura Carbone, Elizabeth M Cespedes Feliciano, Deepika R Laddu, Peter F Schnatz, Aladdin H Shadyab, Marcia L Stefanick, Jean Wactawski-Wende, Carolyn J Crandall, Helena Johansson, Eugene McCloskey
In the Women's Health Initiative (WHI), we investigated associations between baseline DXA appendicular lean mass (ALM) and risk of incident fractures, falls and mortality (separately for each outcome) amongst older postmenopausal women, accounting for bone mineral density (BMD), prior falls and FRAX probability. The WHI is a prospective study of postmenopausal women undertaken at 40 US sites. We used an extension of Poisson regression to investigate the relationship between baseline ALM (corrected for height2 ) and incident fracture outcomes, presented for major osteoporotic fracture [MOF (hip, clinical vertebral, forearm or proximal humerus)], falls and death...
January 15, 2021: Journal of Bone and Mineral Research