Salvatore Minisola, Andrew Arnold, Zhanna Belaya, Maria Luisa Brandi, Bart L Clarke, Fadil M Hannan, Lorenz C Hofbauer, Karl L Insogna, André Lacroix, Uri Liberman, Andrea Palermo, Jessica Pepe, René Rizzoli, Robert Wermers, Rajesh V Thakker
In this narrative review, we present data gathered over four decades (1980-2020) on the epidemiology, pathophysiology and genetics of primary hyperparathyroidism (PHPT). PHPT is typically a disease of postmenopausal women, but its prevalence and incidence vary globally and depend on a number of factors, the most important being the availability to measure serum calcium and parathyroid hormone levels for screening. In the Western world, the change in presentation to asymptomatic PHPT is likely to occur, over time also, in Eastern regions...
August 3, 2022: Journal of Bone and Mineral Research