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JOURNAL ARTICLE
Mohammad Sayed Abdel-Kader, Ahmed Mohammad Sayed, Sondos Mohammad Sayed, Mostafa AbdelRazek
OBJECTIVE: To evaluate efficacy and safety of either or both silodosin and mirabegron as MET for distal ureteric stones ≤ 10 mm. PATIENTS AND METHODS: This study enrolled a total of 105 patients, aged between 20 and 56 years, diagnosed by single radiopaque distal ureteral stone measuring ≤ 10 mm. The recruitment period spanned from May 2020 to December 2021. The patients were randomly divided into three groups, with each group consisting of 35 participants...
December 2, 2023: International Urology and Nephrology
#2
JOURNAL ARTICLE
Neslihan Günay, İsmail Dursun, İbrahim Gökçe, Mehtap Akbalık Kara, Demet Tekcan, Neslihan Çiçek, Meral Torun Bayram, Mustafa Koyun, Nida Dinçel, Hasan Dursun, Seha Saygılı, Zeynep Nagehan Yürük Yıldırım, Selçuk Yüksel, Osman Dönmez, Sibel Yel, Beltinge Demircioğlu Kılıç, Özlem Aydoğ, Bahriye Atmış, Aysun Çaltık Yılmaz, Sevcan A Bakkaloğlu, Mehmet Baha Aytaç, Mehmet Taşdemir, Belde Kasap Demir, Alper Soylu, Elif Çomak, Aslı Kantar Özşahin, Alper Kaçar, Nur Canpolat, Alev Yılmaz, İlknur Girişgen, Kadirye Betül Akkoyunlu, Harika Alpay, Hakan M Poyrazoğlu
BACKGROUND: C3 glomerulopathy (C3G) is a complement-mediated disease. Although genetic studies are not required for diagnosis, they are valuable for treatment planning and prognosis prediction. The aim of this study is to investigate the clinical phenotypes, kidney survival, and response to mycophenolate mofetil (MMF) treatment in pediatric C3G patients with and without mutations in complement-related genes. METHODS: Sixty pediatric C3G patients were included, divided into two groups based on complement-related gene mutations...
December 2, 2023: Pediatric Nephrology
#3
JOURNAL ARTICLE
Kangwen He, Dongyi Wan, Shichao Li, Guanjie Yuan, Mengmeng Gao, Yunfeng Han, Zhen Li, Daoyu Hu, Xiaoyan Meng, Yonghua Niu
BACKGROUND: Split kidney function (SKF) is critical for treatment decision in pediatric patients with hydronephrosis and is commonly measured using renal scintigraphy (RS). Non-contrast-enhanced magnetic resonance urography (NCE-MRU) is increasingly used in clinical practice. This study aimed to investigate the feasibility of using NCE-MRU as an alternative to estimate SKF in pediatric patients with hydronephrosis, compared to RS. METHODS: Seventy-five pediatric patients with hydronephrosis were included in this retrospective study...
December 2, 2023: Pediatric Nephrology
#4
EDITORIAL
Giorgina Barbara Piccoli, Hafedh Fessi, Alexandre Karsenti
No abstract text is available yet for this article.
December 2, 2023: Journal of Nephrology
#5
JOURNAL ARTICLE
Çağla Serpil Doğan, Sevgin Taner, Betül Durucu Tiryaki, Demet Alaygut, Neşe Özkayın, Aslıhan Kara, Aylin Gençler, Ayşe Seda Pınarbaşı, Hülya Nalçacıoğlu, Selçuk Yüksel, Okan Akacı, Esra Karabağ Yılmaz, Sevgi Yavuz, Kenan Doğan, Rumeysa Yasemin Çiçek Gülşan, Gülşah Kaya Aksoy, Neslihan Çiçek, Bağdagül Aksu, Nuran Küçük, Fatma Şemsa Altugan, Şenay Zırhlı Selçuk, Funda Baştuğ, Gökçen Erfidan, Bahriye Atmış, Arife Uslu Gökçeoğlu, Esra Nagehan Akyol Önder, Ahmet Mithat Elmacı, Nurcan Cengiz, Kaan Gülleroğlu, Ebru Bekiroğlu Yılmaz, Aslı Çelebi Tayfur, Gülsün Gülay Yılmaz, Sİbel Yel, Cemile Pehlivanoğlu, Cihangir Akgün, Mehtap Akbalık Kara, Beltinge Demircioğlu Kılıç, Özgür Özdemir Şimşek, Melike Yucal, Buket Esen Ağar, Metin Kaya Gürgöze, İsmail Yağmur, Ömer Madsar, Demet Tekcan Karalı, İlknur Girişgen, Ece Demirci Bodur, Elif Çomak, İbrahim Gökçe, Mehtap Kaya, Yılmaz Tabel, Neslihan Günay, Rüveyda Gülmez, Salim Çalışkan
BACKGROUND: Myelomeningocele (MMC) is highly prevalent in developing countries, and MMC-related neurogenic bladder is an important cause of childhood chronic kidney disease (CKD). This nationwide study aimed to evaluate demographic and clinical features of pediatric patients with MMC in Turkey and risk factors associated with CKD stage 5. METHODS: Data from children aged 0-19 years old, living with MMC in 2022, were retrospectively collected from 27 pediatric nephrology centers...
December 2, 2023: Pediatric Nephrology
#6
JOURNAL ARTICLE
Sarah J Glastras, Carol A Pollock
No abstract text is available yet for this article.
December 1, 2023: Nature Reviews. Nephrology
#7
JOURNAL ARTICLE
Meizhi He, Zhao Liu, Li Li, Youhua Liu
Kidney fibrosis is a common outcome of a wide variety of chronic kidney diseases, in which virtually all kinds of renal resident and infiltrating cells are involved. As such, well-orchestrated intercellular communication is of vital importance in coordinating complex actions during renal fibrogenesis. Cell-cell communication in multicellular organisms is traditionally assumed to be mediated by direct cell contact or soluble factors, including growth factors, cytokines and chemokines, through autocrine, paracrine, endocrine and juxtacrine signaling mechanisms...
December 1, 2023: Nephrology, Dialysis, Transplantation
#8
JOURNAL ARTICLE
Sarah Brand, Sunil Daga, Kirit Mistry, Mohamed Morsy, Atul Bagul, Rizwan Hamer, Shafi Malik
OBJECTIVES: Kidney transplantation offers patients better quality of life and survival compared with dialysis. The risk of end stage renal disease is higher among ethnic minorities and they experience longer wait times on transplant lists. This inequality stems from a high need for kidney transplantation combined with a low rate of deceased donation among ethnic minority groups. This study aimed to explore the perspectives around living donor kidney transplantation of members of the Sikh and Muslim communities with an aim to develop a digital intervention to overcome any barriers...
December 1, 2023: BMJ Open
#9
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
December 1, 2023: Journal of the American Society of Nephrology: JASN
#10
JOURNAL ARTICLE
Aleksandar Denic, Aperna Fnu, Kumar Mahesh, Andrew D Rule
No abstract text is available yet for this article.
December 1, 2023: Journal of the American Society of Nephrology: JASN
#11
JOURNAL ARTICLE
Takaya Sasaki, Nobuo Tsuboi
No abstract text is available yet for this article.
December 1, 2023: Journal of the American Society of Nephrology: JASN
#12
JOURNAL ARTICLE
Norberto Perico, Matthew D Griffin, Federica Casiraghi, Giuseppe Remuzzi
No abstract text is available yet for this article.
December 1, 2023: Journal of the American Society of Nephrology: JASN
#13
JOURNAL ARTICLE
Jun-Zhang Chen, Bo Liang
No abstract text is available yet for this article.
December 1, 2023: Journal of the American Society of Nephrology: JASN
#14
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
December 1, 2023: Journal of the American Society of Nephrology: JASN
#15
JOURNAL ARTICLE
Gemma Scholes, Bridget Strasser, Alan Pham, Gopal Basu, Peggy Teh
No abstract text is available yet for this article.
December 1, 2023: Journal of Nephrology
#16
JOURNAL ARTICLE
Emre Leventoğlu, Emine Dönmez, Bahriye Uzun Kenan, Burcu Yazıcıoğlu, Bahar Büyükkaragöz, Kibriya Fidan, Sevcan A Bakkaloğlu, Oğuz Söylemezoğlu
Pierson syndrome (PS) is a rare autosomal recessive disease, characterized by congenital nephrotic syndrome (CNS), and ocular and neurologic abnormalities. In affected cases, there is abnormal b-2 laminin which is compound of the several basement membranes caused by inherited mutations in the LAMB2 gene. Although patients have mutations in the same gene, the phenotype is highly variable. In this case series, the relationship between genotype and phenotype is emphasized, and information about the clinical follow-up of the patients is presented...
December 1, 2023: CEN Case Reports
#17
REVIEW
Xingmu Wang, Ge Shi, Gangfeng Li, Guiliang Tang
OBJECTIVE: Parathyroidectomy (PTX) is the conclusive therapy for primary hyperparathyroidism (PHPT), but its effect on the risk of urolithiasis is inconclusive. We comprehensively reviewed the currently available research to investigate the impact of PTX on the likelihood of urolithiasis among individuals suffering PHPT. METHODS: Internet-based articles in English language released on Cochrane, PubMed, Scopus, Web of knowledge, and Embase up to September, 2023 were comprehensively reviewed...
December 1, 2023: International Urology and Nephrology
#18
REVIEW
Srijan Chatterjee, Manojit Bhattacharya, Soumen Pal, Sang-Soo Lee, Chiranjib Chakraborty
ChatGPT has quickly popularized since its release in November 2022. Currently, large language models (LLMs) and ChatGPT have been applied in various domains of medical science, including in cardiology, nephrology, orthopedics, ophthalmology, gastroenterology, and radiology. Researchers are exploring the potential of LLMs and ChatGPT for clinicians and surgeons in every domain. This study discusses how ChatGPT can help orthopedic clinicians and surgeons perform various medical tasks. LLMs and ChatGPT can help the patient community by providing suggestions and diagnostic guidelines...
December 1, 2023: Journal of Experimental Orthopaedics
#19
JOURNAL ARTICLE
Amar D Bansal, Arpan A Patel
PURPOSE OF REVIEW: The purpose of this review is to describe an approach that emphasizes shared decision-making for patients with decompensated cirrhosis and acute kidney injury when liver transplantation is either not an option, or unlikely to be an option. RECENT FINDINGS: When acute kidney injury occurs on a background of decompensated cirrhosis, outcomes are generally poor. Providers can also be faced with prognostic uncertainty. A lack of guidance from nephrology and hepatology professional societies means that providers rely on expert opinion or institutional practice patterns...
December 4, 2023: Current Opinion in Nephrology and Hypertension
#20
JOURNAL ARTICLE
Eleni Stamellou, Shipra Agrawal, Florian Siegerist, Marc Buse, Christoph Kuppe, Tim Lange, Eva Miriam Buhl, Jessica Alam, Thiago Strieder, Peter Boor, Tammo Ostendorf, Hermann-Josef Gröne, Jürgen Floege, William E Smoyer, Nicole Endlich, Marcus J Moeller
BACKGROUND AND HYPOTHESIS: Glucocorticoids are the treatment of choice for proteinuric patients with minimal-change disease (MCD) and primary focal and segmental glomerulosclerosis (FSGS). Immunosuppressive as well as direct effects on podocytes are believed to mediate their actions. In this study, we analyzed the anti-proteinuric effects of inhibition of the glucocorticoid receptor (GR) in glomerular epithelial cells, including podocytes. METHODS: We employed genetic and pharmacological approaches to inhibit the GR...
November 30, 2023: Nephrology, Dialysis, Transplantation
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