Rocío Romero, Rocío Penas, Ana García-Conde, Pilar Llombart, Sandra Pérez, José H Marco
OBJECTIVES: The aim of this study is to analyse whether MBCT will reduce the general level of psychopathology, increase the quality of life, and increase meta-knowledge about their emotional state in Spanish participants with cancer. METHOD: The sample consisted of n = 88 Spanish oncology patients. This was a non-randomized, two-group (experimental vs waiting list) trial conducted in a naturalistic setting. We evaluated psychological distress (BSI-18), quality of life (FACT-G), and meta-knowledge of emotions (TMMS-24)...
November 2020: Psicothema
Sophie Scherer, Lina Jansen, Daniel Boakye, Michael Hoffmeister, Hermann Brenner
BACKGROUND: Colorectal cancer (CRC) and its treatment can lead to several physical and psychosocial impairments. Cancer rehabilitation aims to reduce morbidity and improve quality of life. The objective of this review was to summarize and evaluate evidence on changes in health-related outcomes among CRC patients undergoing inpatient rehabilitation therapy and on the effectiveness of such treatment. MATERIAL AND METHODS: We conducted a systematic literature search including the electronic databases Pubmed and Web of Science to find observational and interventional studies, which investigated changes in health-related outcomes among CRC patients undergoing multidisciplinary inpatient rehabilitation programs or treatment effects...
October 19, 2020: Acta Oncologica
Ali Alias, Maria Rideout, Raymond You, Raphael Lencucha
BACKGROUND: Rehabilitation practice is increasingly tied to global trends. First, healthcare services are increasingly tailored to be patient-centered, requiring knowledge of sociocultural contexts and experiences of a diverse patient population. Second, non-communicable diseases and morbidity stemming from infectious diseases are creating greater needs for rehabilitation services in countries facing this double burden of disease. Third, globalization continues to shape the risk factors for disease and disability and influences the type of services accessible and the financing and management of such services...
October 18, 2020: Disability and Rehabilitation
Joanna Wardlaw, Philip M W Bath, Fergus Doubal, Anna Heye, Nikola Sprigg, Lisa J Woodhouse, Gordon Blair, Jason Appleton, Vera Cvoro, Timothy England, Ahamad Hassan, David John Werring, Alan Montgomery
Background: Small vessel disease causes a quarter of ischaemic strokes (lacunar subtype), up to 45% of dementia either as vascular or mixed types, cognitive impairment and physical frailty. However, there is no specific treatment to prevent progression of small vessel disease. Aim: We designed the LACunar Intervention Trial-2 (LACI-2) to test feasibility of a large trial testing cilostazol and/or isosorbide mononitrate (ISMN) by demonstrating adequate participant recruitment and retention in follow-up, drug tolerability, safety and confirm outcome event rates required to power a phase 3 trial...
September 2020: European Stroke Journal
Karl Schranz, Daltrey Meitz, Bethany Powers, Adrienne Ables
Complex regional pain syndrome (CRPS) is a challenging disease to treat and requires a multidisciplinary and multimodal approach. We discuss the use of a novel approach to counterstrain using irritants - as identified by the patient - to induce symptoms of neuropathy and paresthesia and treat these symptoms as if they were counterstrain tender points. This treatment approach to CRPS has not previously been described in osteopathic manipulative treatment (OMT) literature, including Foundations of Osteopathic Medicine...
October 14, 2020: Curēus
Sajad Mansouri, Amir Jalali, Mahmoud Rahmati, Nader Salari
Background: In addition to physical, mental, and social condition, ESRD and hemodialysis affect the quality of life of patients as well. Psychotherapy and non-pharmaceutical interventions are effective measures to add meaning to life, create a goal and motivation in life, and improve the quality of life in chronic patients. The effect of educational and supportive group therapy on the quality of life (QOL) of hemodialysis patients was examined. Methods: The study was carried out as an interventional quasi-experimental study with the participation of 64 patients who were selected through convenience sampling and based on the patient's hemodialysis days (Saturday, Monday, and Wednesday patients as an experimental group and Sunday, Tuesday, and Thursday patients as a control group)...
2020: BioPsychoSocial Medicine
Christopher D Busack, Bernard E Eagleton
Background: New neurologic deficits after spine surgery occur in less than 1% of cases. A particularly rare complication is white cord syndrome, a neurologic deterioration in the absence of obvious perioperative injury with concurrent hyperintense signal change on T2-weighted magnetic resonance imaging. The pathophysiologic mechanism is hypothesized to be an ischemia-reperfusion injury after the decompression of a chronically ischemic cord. Case Report: A 63-year-old male underwent posterior cervical decompression and fusion for severe cervical stenosis and myelopathy...
2020: Ochsner Journal
Scott Mayer, Blake S Raggio, Adam Master, Nicholas Lygizos
Background: Langerhans cell histiocytosis (LCH) of the temporal bone is an uncommon disease that primarily affects the pediatric population; fewer than 40 adult cases have been reported in the literature. We present a rare case of LCH of the temporal bone in an adult patient and describe its clinical presentation, histopathologic findings, and management. Case Report : A 21-year-old male presented to the emergency department with progressively worsening right-sided ear pain refractory to outpatient oral antibiotics...
2020: Ochsner Journal
Yutaro Yamamoto, Yoshio Nagai, Shin Kawanabe, Yoshiaki Hishida, Koji Hiraki, Masakatsu Sone, Yasushi Tanaka
Type 2 diabetes is associated with sarcopenia. Resistance training and appropriate nutritional therapy are reported to be effective for muscle strength and mass. This study aimed to evaluate the effect of resistance training using elastic bands at home combined with a leucine-rich amino acid supplement on muscle strength, physical function, and muscle mass in elderly type 2 diabetes. We conducted a 48-week prospective single-center randomized controlled trial in 60 patients who were randomly allocated to one of three groups: control (C), resistance exercise (R), and resistance exercise plus supplement (RL)...
October 17, 2020: Endocrine Journal
Daan M van Velzen, Nienke M Nota, Suat Simsek, Elfi B Conemans, Guy T'Sjoen, Martin den Heijer
Objective: Transgender individuals sometimes report a lack of physical change during hormone treatment, such as alterations in muscle tone or fat distribution. Identifying characteristics of this subgroup could be a step toward individualizing hormone therapy in transgender individuals. Therefore, we study the variation of changes in body composition and characteristics associated with a lack of change. Design and methods: Body composition measures were recorded in 323 transmen and 288 transwomen at every visit from the start of hormone therapy to a maximum of 24 months follow-up...
November 2020: European Journal of Endocrinology
Evander Meneses, Kyle Kinslow, Mark McKenney, Adel Elkbuli
Each year, traumatic injuries affect 2.6 million adults in the United States leading to significant health problems. Although many sequelae stem directly from physical manifestations of one's sustained injuries, mental health may also be affected in the form of post-traumatic stress disorder (PTSD). PTSD can lead to decreased physical recovery, social functioning, and quality of life. Several screening tools such as the Injured Trauma Survivor Screen, PTSD CheckList, Primary Care PTSD, and Clinician-Administered PTSD Scale for DSM-5 have been used for initial PTSD screening of the trauma patient...
October 15, 2020: Journal of Surgical Research
C Antileo-Pinto, A Lara-Madrid, N Montecinos-Muñoz, P Castillo-Orellana, S Martínez-Huenchullán
OBJECTIVE: To evaluate the association between hospital stay, functional status and physical therapy delay (PT delay) in patients admitted to a surgery unit of a high complexity hospital. MATERIALS AND METHODS: Observational, analytic and cross-sectional study. We included 279 patients (124 women). Days of PT delay (calculated as the difference between hospital admission and start of PT), days of bed rest, prolonged hospital stay (75th percentile of bed rest days), and functional status were registered to investigate the influence of PT delay on these variables...
October 15, 2020: Rehabilitación
Glenn Choon Lim Wong, Ted Kheng Siang Ng, Jia Le Lee, Pei Yi Lim, Sean Kai Jie Chua, Crystal Tan, Michelle Chua, Janice Tan, Samantha Lee, Angelia Sia, Maxel K W Ng, Rathi Mahendran, Ee Heok Kua, Roger C M Ho, Anis Larbi
BACKGROUND: With the challenges that aging populations pose to healthcare, interventions that facilitate alleviation of age-related morbidities are imperative. A prominent risk factor for developing age-related morbidities is immunosenescence, characterized by increased chronic low-grade inflammation, resulting in T-cell exhaustion and senescence. Contact with nature and associated physical activities have been shown to boost immunity in older adults and may be promoted in the form of Horticultural Therapy (HT)...
October 18, 2020: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Christina Durrough, Juan M Colazo, Jill Simmons, Margaret Hudson, Jiun-Ruey Hu, Margo Black, Michael de Riesthal, Kathryn Dahir
OBJECTIVE: Given the small but growing body of literature related to physical functioning and the scarce data related to fine motor and cognitive functioning in adults with hypophosphatasia (HPP), our objective was to characterize physical, functional, and cognitive performance in adults with HPP. A future objective is to utilize this characterization to develop guidelines for evaluation by physical therapists (PT), occupational therapists (OT), and speech-language pathologists (SLP)...
October 15, 2020: Bone
Hamouda Abassi, Fanny Bajolle, Oscar Werner, Annie Auer, Amandine Marquina, Thibault Mura, Kathleen Lavastre, Sophie Guillaumont, Federico Manna, Pascal Auquier, Damien Bonnet, Pascal Amedro
BACKGROUND: Managing oral anticoagulant therapy with vitamin K antagonists remains challenging in paediatric medicine. AIMS: This study aimed to assess the correlation between time in therapeutic range and quality of life in children participating in a non-selective International Normalised Ratio self-monitoring and vitamin K antagonist education programme. METHODS: Children aged from 2 to 18 years and receiving vitamin K antagonist therapy were eligible for this prospective multicentre study...
October 14, 2020: Archives of Cardiovascular Diseases
Giorgia Meschini, Alessandro Vai, Chiara Paganelli, Silvia Molinelli, Davide Maestri, Giulia Fontana, Andrea Pella, Viviana Vitolo, Francesca Valvo, Mario Ciocca, Guido Baroni
PURPOSE: To generate virtual 4DCT from 4DMRI with field of view (FOV) extended to the entire involved patient anatomy, in order to evaluate its use in carbon ion radiation therapy (CIRT) of the abdominal site in a clinical scenario. MATERIALS AND METHODS: The virtual 4DCT was generated by deforming a reference CT in order to (1) match the anatomy depicted in the 4DMRI within its FOV, by calculating deformation fields with deformable image registration to describe inter-fractional and breathing motion, and (2) obtain physically plausible deformation outside of the 4DMRI FOV, by propagating and modulating the previously obtained deformation fields...
October 14, 2020: Zeitschrift Für Medizinische Physik
Muddasarul Hoda
Conventional cancer therapeutic approaches broadly include chemotherapy, radiation therapy and surgery. These established approaches have evolved over several decades of clinical experience. For a complex disease like cancer, satisfactory treatment remains an enigma for the simple fact that that the causal factors for cancer is extremely diverse. In order to overcome existing therapeutic limitations, consistent scientific endeavors have evolved several potential therapeutic approaches, majority of which focuses essentially on targeted drug delivery, minimal concomitant ramification, and selective high cytotoxicity...
October 16, 2020: Current Pharmaceutical Biotechnology
Filippo Familiari, Suresh K Nayar, Raffaella Russo, Marco De Gori, Francesco Ranuccio, Valerio Mastroianni, Ermes Giuzio, Olimpio Galasso, Giorgio Gasparini, Edward G McFarland, Uma Srikumaran
PURPOSE: To investigate associations between clinical/demographic parameters and Constant-Murley (CM) scores after subacromial balloon placement for massive, irreparable rotator cuff tears (MIRCTs) and to evaluate implant survival, shoulder function, and patient satisfaction. METHODS: We prospectively analyzed patients with rotator cuff tears deemed irreparable on preoperative MRI for whom nonoperative therapy was unsuccessful and who underwent balloon placement from 2014-2017 with minimum 1-year follow-up...
October 14, 2020: Arthroscopy
Xia Chen, Wei Huang, Bao-Yan Liu, Hua Wang, Li-Yun He, Hong Zhao, Wei-Juan Gang, Dan Wei, De-Guang Ding, Hong-Ling Pan, Jie-Yu Wang, Jin-Yan Teng, Hui-Fang Mao, San-Chun Tan, Xin-Yin Xu, Min Yao, Si-Min Liu, Yan Li, Qin Wang, Yi-Ran Liu, Le Yu, Chen Shen, Jia-Jie Wang, Yan Cheng, Ming-Ming Zhan, Yi-Wei Zheng, Ai-Qun Song, Zhong-Yu Zhou, Xiang-Hong Jing
OBJECTIVE: To establish and promote the non-contact doctor-patient interactive diagnosis and treatment mode based on mobile internet for the treatment of coronavirus disease 2019 (COVID-19) with moxibustion therapy, and to observe the feasibility and effectiveness of the model in the pandemic. METHODS: A total of 43 first-line medical staff and 149 suspected and confirmed cases with COVID-19 [18 cases in medical observation period, 17 cases of mild type (cold dampness and stagnation in the lung), 24 cases of ordinary type (cold-dampness accumulated in the lung) and 90 cases in recovery period ( qi deficiency of spleen and lung)] were included...
October 12, 2020: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Max O Krucoff, Robert Gramer, Dana Lott, Emily Kale, Amol P Yadav, Muhammad M Abd-El-Barr, Saurabh R Sinha, Shivanand P Lad
INTRODUCTION: Epidural electrical stimulation of the conus medullaris has helped facilitate native motor recovery in individuals with complete cervicothoracic spinal cord injuries (SCI). A theorized mechanism of clinical improvement includes supporting central pattern generators intrinsic to the conus medullaris. Because spinal cord stimulators (SCS) are approved for the treatment of neuropathic pain, we were able to test this experimental therapy in a subject with complete L1 paraplegia and neuropathic genital pain due to a traumatic conus injury...
October 16, 2020: Spinal Cord Series and Cases
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