Wenwei Shao, Yixuan Wang, Li Liu, Yiran Ren, Jieru Wang, Yuqing Cui, Jia Liu, Xiaoyu Zhang, Sudong Zhang, Shuangjie Liu, Erlie Jiang, Sizhou Feng, Xiaolei Pei
Infection post-hematopoietic stem cell transplantation (HSCT) is one of the main causes of patient mortality. Fever is the most crucial clinical symptom indicating infection. However, current microbial detection methods are limited. Therefore, timely diagnosis of infectious fever and administration of antimicrobial drugs can effectively reduce patient mortality. In this study, serum samples were collected from 181 patients with HSCT with or without infection, as well as the clinical information. And more than 80 infectious-related microRNAs in the serum were selected according to the bulk RNA-seq result and detected in the 345 time-pointed serum samples by Q-PCR...
May 1, 2024: Annals of Hematology