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JOURNAL ARTICLE
Flavia Fusco, Giancarlo Scognamiglio, Davide Sorice, Massimiliana Abbate, Ippolita Altobelli, Berardo Sarubbi
To evaluate biventricular mechanics by means of echo-derived myocardial work (MW) analysis in patients with a systemic right ventricle (sRV). Comprehensive echo data were collected in all patients with a sRV who underwent transthoracic echocardiography at our tertiary centre between 2020 and 2021 including sRV function indices, global longitudinal strain (GLS) of right and left ventricle (RV/LV), biventricular MW, and atrial strain in those with congenitally corrected transposition of the great arteries (ccTGA)...
April 5, 2024: International Journal of Cardiovascular Imaging
#2
Sweta Sahu, Varnika Gupta, Mahendra Kumar, Bala Sai Teja Nuthalapati, Pulkit Johar, Veeresh Babu Halvi, Roopeessh Vempati
Acute stroke and the transposition of great arteries are two distinct medical entities that rarely intersect in clinical practice. Acute stroke, a devastating neurological event, occurs due to a sudden interruption of blood flow to the brain, leading to focal neurological deficits. On the other hand, the transposition of great arteries is a congenital heart defect characterized by a complete reversal of the aorta and pulmonary artery, resulting in abnormal blood circulation. Traditionally, transposition of great arteries is diagnosed in infancy and managed with surgical interventions...
February 2024: Curēus
#3
Nakeya Dewaswala, Michael David Bolanos, Huzefa Bhopalwala, Hassan Reda, Andrew Leventhal
• ccTGA accounts for 0.5%-1.4% of patients with congenital heart disease. • Patients with isolated ccTGA can remain undiagnosed for decades. • Very rarely, patients with ccTGA develop symptomatic AS. • Management of severe AS in patients with ccTGA presents unique challenges. • Transcatheter options are limited due to the unique anatomy.
March 2024: CASE: Cardiovascular Imaging Case Reports
#4
JOURNAL ARTICLE
Maria Kavga, Adeolu Banjoko, Esther Poole, John Stickley, Tarak Desai, Paul Miller, Michael Harris, Adrian Crucean, Natasha Khan, Anna N Seale
Congenitally corrected transposition of the great arteries (ccTGA) is a rare malformation with diverse morphology. We assessed features of fetuses with ccTGA and evaluated neonatal and pediatric outcomes. This was a retrospective review of fetuses with ccTGA at Birmingham Women's and Children's Hospital born from 2005 to 2019. Of thirty-six fetuses identified, six had unavailable prenatal data, one was postnatally diagnosed with isomerism and 29 fetuses were evaluated. ccTGA without associated cardiac lesions was found in 28% (8/29), ccTGA with significant VSD in 31% (9/29), ccTGA with pulmonary obstruction in 24% (7/29) and ccTGA with complex anomalies in 17% (5/29)...
March 21, 2024: Pediatric Cardiology
#5
REVIEW
Amalia Baroutidou, Despoina Ntiloudi, Nearchos Kasinos, Evangelia Nyktari, George Giannakoulas
A comprehensive and structured imaging approach in the evaluation of the systemic right ventricle (sRV) in patients with complete transposition of the great arteries (TGA) after atrial switch procedure and congenitally corrected transposition of the great arteries (ccTGA) is a key for their optimal lifelong surveillance. Despite the improvements in cardiovascular imaging of adults with congenital heart disease (ACHD), the imaging of sRV remains an ongoing challenge due to its complex morphology and the difficulty in applying the existing knowledge for the systemic left ventricle...
January 2024: Echocardiography
#6
JOURNAL ARTICLE
Anish Bhargav, Suresh Kumar Sukumaran, Sridhar Balaguru, Raja J Selvaraj
A 51-year-old female with congenitally corrected transposition of great arteries (CCTGA), situs solitus, dextrocardia, atrial septal defect and persistent left superior vena cava underwent electrophysiology study for recurrent palpitations with documented narrow complex, short RP tachycardia. With a catheter in the region of the anterior mitral annulus, a His signal was recorded and HV interval was 35 msec. Tachycardia was induced with a ventricular extrastimulus. During the tachycardia there was 1:1 ventriculo-atrial conduction and central atrial activation with a VA interval of 20 msec...
January 24, 2024: Pacing and Clinical Electrophysiology: PACE
#7
JOURNAL ARTICLE
William R Miranda, C Charles Jain, Alexander C Egbe, Yogesh N Reddy, Joseph A Dearani, Donald J Hagler, Heidi M Connolly
Despite their anatomical differences, congenitally corrected (ccTGA) and complete transposition of the great arteries (d-TGA) post-atrial switch are frequently studied together and managed similarly from a medical standpoint due to the shared systemic right ventricle (sRV). The aim was to assess differences in their underlying hemodynamics. The study is a retrospective review of 138 adults with ccTGA or d-TGA post-atrial switch undergoing cardiac catheterization at Mayo Clinic, MN between 2000 and 2021...
January 17, 2024: Pediatric Cardiology
#8
Diwakar Turaga, Xiao Li, Yi Zhao, Chang-Ru Tsai, Axel Moreira, Edward Hickey, Iki Adachi, James Martin
The right ventricle (RV) is one of the four pumping chambers of the heart, pumping blood to the lungs. In severe forms of congenital heart disease and pulmonary hypertension, the RV is made to pump into the systemic circulation. Such systemic RVs typically display early failure due to pressure overload. In rare cases a systemic RV persists into later decades of life - colloquially called a 'Super RV'. Here we present the single-nucleus transcriptome of a systemic RV from a 60-year-old with congenitally corrected transposition of great arteries (ccTGA)...
January 3, 2024: bioRxiv
#9
JOURNAL ARTICLE
Antonia Schulz, Edward Buratto, Shuta Ishigami, Igor E Konstantinov, Michael M H Cheung, Christian P Brizard
OBJECTIVES: The Bex-Nikaidoh operation can effectively relieve left ventricular outflow tract obstruction. However, if a conduit is used for right ventricular outflow tract reconstruction, late reoperation can be anticipated. We examined the impact of double root translocation on outcomes. METHODS: This is a retrospective single-center study of patients who underwent aortic root translocation between 2006 and 2019. RESULTS: Aortic root translocation was performed in 23 patients at a median age of 1...
December 11, 2023: European Journal of Cardio-thoracic Surgery
#10
JOURNAL ARTICLE
Ahmed A Abdelrehim, Elizabeth H Stephens, William R Miranda, Austin L Todd, Heidi M Connolly, Alexander C Egbe, Luke J Burchill, Elena A Ashikhmina, Joseph A Dearani
BACKGROUND: Limited data exist regarding the long-term outcomes of systemic atrioventricular valve (SAVV) intervention (morphologic tricuspid valve) in congenitally corrected transposition (ccTGA). OBJECTIVES: The goal of this study was to evaluate the mid- and long-term outcomes of SAVV surgery in ccTGA. METHODS: We performed a retrospective review of 108 ccTGA patients undergoing SAVV surgery from 1979 to 2022. The primary outcome was a composite endpoint of mortality, cardiac transplantation, or ventricular assist device implantation...
December 5, 2023: Journal of the American College of Cardiology
#11
JOURNAL ARTICLE
Dan M Dorobantu, Nurul H Amir, Curtis A Wadey, Chetanya Sharma, A Graham Stuart, Craig A Williams, Guido E Pieles
BACKGROUND: Speckle tracking echocardiography (STE) is now routinely included in cardiac evaluations, but its role in predicting mortality and morbidity in congenital heart disease (CHD) is not well described. We conducted a systematic review to evaluate the prognostic value of STE in patients with CHD. METHODS: EMBASE, Medline, Web of Science, Scopus and CENTRAL databases were searched from inception to January 2023, for terms related to all CHD, STE and prognosis...
November 14, 2023: Journal of the American Society of Echocardiography
#12
JOURNAL ARTICLE
Utkarsh Kohli, Melissa L Perrotta, Saif Aljemmali, Cyndi Sosnowski, Yvonne M Cardenas, Kavita Sharma
Complex congenital heart disease (CHD) in each of dichorionic diamniotic (DiDi) twin pairs is extremely rare and has not been well characterized. Four DiDi twin pairs were included in this multi-institutional case series. The congenital cardiac abnormalities noted included tetralogy of Fallot (ToF) with pulmonary atresia and collaterals (n = 1), ToF with absent pulmonary valve (n = 1), ToF (n = 2), discontinuous right pulmonary artery (RPA) (n = 1), tricuspid atresia (TA) with normally related great arteries and pulmonary valve stenosis or atresia (n = 2) and coarctation of aorta (CoA) with bicuspid aortic valve (BAV) and borderline left-sided structures (n = 1)...
November 15, 2023: Pediatric Cardiology
#13
JOURNAL ARTICLE
William H Marshall V, May Ling Mah, Jennifer DeSalvo, Saurabh Rajpal, Lauren T Lastinger, Arash Salavitabar, Aimee K Armstrong, Darren Berman, Brent Lampert, Lydia K Wright, Jenne Hickey, Rachel Metzger, Deipanjan Nandi, Robert Gajarski, Curt J Daniels
BACKGROUND: Pulmonary hypertension (PH) is a common complication in patients with complete dextro-transposition of the great arteries (TGA) after atrial switch (D-TGA/AS) and congenitally corrected TGA (ccTGA). In this population with subaortic right ventricles (sRVs), echocardiography is a poor screening tool for PH; implantable invasive haemodynamic monitoring (IHM) could be used for this purpose, but data are limited. The aim of this study is to report on novel uses of IHM in patients with sRV...
November 7, 2023: Heart
#14
Emily E Naoum, Jamel P Ortoleva, Ryan M Militana, Marti D Soffer, Doreen DeFaria Yeh
Congenitally corrected transposition of the great arteries (CCTGA) is a rare form of congenital heart disease often associated with other cardiac defects. The adaptations and physiologic changes in pregnancy can present maternal challenges and complications; multidisciplinary care allows for the safest management of pregnancy and delivery in these patients. We present a case of the anesthetic management of cesarean delivery in a woman with CCTGA with her pregnancy complicated by recurrent volume overload, pulmonary hypertension, and dysrhythmias...
2023: Annals of Cardiac Anaesthesia
#15
JOURNAL ARTICLE
Laura Seese, Carlos Diaz Castrillon, Luciana Da Fonseca Da Silva, Shwetabh Tarun, Mario Castro-Medina, Melita Viegas, Jose P Da Silva, Victor O Morell
BACKGROUND: Studies that have assessed the Rastelli and Nikaidoh operations for transposition of the great arteries (TGA) with obstructed left ventricular outflow tract obstruction (LVOTO) have not fully evaluated the anatomic drivers that may contribute to surgical selection. We present our procedural selection process for optimizing outcomes of complex TGA in the modern era. METHODS: This is a single-center, retrospective study that included pediatric patients who underwent either a Nikaidoh or Rastelli operation for the treatment of TGA-LVOTO, congenitally corrected TGA-LVOTO, or double-outlet right ventricle TGA type-LVOTO from June 2004 to June 2021...
September 28, 2023: Annals of Thoracic Surgery
#16
Jakub Šimka, Kamil Sedláček, Rudolf Praus, Petr Pařízek
BACKGROUND: Congenitally corrected transposition of the great arteries (CCTGA) is a rare congenital heart anomaly. Physiological correction may be associated with a long pre-symptomatic period in many patients and delayed accidental diagnosis. Additional related congenital malformations may increase the complexity of cardiac interventions. CASE SUMMARY: A 59-year-old man with known dextrocardia, situs viscerum inversus, and CCTGA was scheduled for upgrading of a dual-chamber pacemaker to cardiac resynchronization therapy to treat heart failure related to a progressive systolic dysfunction of the systemic right ventricle (RV)...
September 2023: European Heart Journal. Case Reports
#17
Murad Almasri, Hamza Salim, Jeffrey Orcutt
In this manuscript, we present an ECG that is diagnostic of congenitally corrected transposition of great arteries (ccTGA) and ask about the arrhythmias associated as well as the management options.
September 2023: European Heart Journal. Case Reports
#18
Benjamin De Becker, Louisa O'Neill, Sophie Pierard, Jean-Benoit Le Polain De Waroux
BACKGROUND: Patients with congenitally corrected transposition of the great arteries (ccTGA) are at risk of developing conduction disease and complete atrio-ventricular block and this risk increases after corrective cardiac surgery. However, the optimum pacing modality remains controversial. CASE SUMMARY: Twelve years after a double-switch surgery with ventricular septal defect correction, a 16-year-old ccTGA female was referred with an indication for cardiac resynchronization therapy...
August 2023: European Heart Journal. Case Reports
#19
JOURNAL ARTICLE
Alexandra C van Dissel, Alexander R Opotowsky, Luke J Burchill, Jamil Aboulhosn, Jasmine Grewal, Adam M Lubert, Petra Antonova, Sangeeta Shah, Timothy Cotts, Anitha S John, William Aaron Kay, Christopher DeZorzi, Anthony Magalski, Frank Han, David Baker, Joseph Kay, Elizabeth Yeung, Isabelle Vonder Muhll, Stephen Pylypchuk, Marissa C Kuo, Jeremy Nicolarsen, Berardo Sarubbi, Flavia Fusco, Susan M Jameson, Jonathan Cramer, Tripti Gupta, Pastora Gallego, Clare O'Donnell, Jane Hannah, Mikael Dellborg, Robert M Kauling, Salil Ginde, Eric V Krieger, Fred Rodriguez, Payam Dehghani, Shelby Kutty, Joshua Wong, William M Wilson, Carla P Rodriguez-Monserrate, Jolien Roos-Hesselink, David S Celermajer, Paul Khairy, Craig S Broberg
BACKGROUND AND AIMS: For patients with congenitally corrected transposition of the great arteries (ccTGA), factors associated with progression to end-stage congestive heart failure (CHF) remain largely unclear. METHODS: This multicentre, retrospective cohort study included adults with ccTGA seen at a congenital heart disease centre. Clinical data from initial and most recent visits were obtained. The composite primary outcome was mechanical circulatory support, heart transplantation, or death...
August 18, 2023: European Heart Journal
#20
JOURNAL ARTICLE
Kamel Shibbani, Awais Ashfaq, Tarek Alsaied, Karim A Diab
In this review, we provide a brief description of recently published articles addressing topics relevant to pediatric cardiologists. This review includes (1) Fetal diagnosis, associated anomalies, and factors affecting outcomes in fetal congenitally corrected transposition of the great arteries (ccTGA), (2) The impact of Fontan-associated liver disease on heart and heart/liver transplant, (3) 1-year outcomes of the Harmony transcatheter pulmonary valve, (4) Risk factors associated with major adverse cardiac events in patients with pulmonary atresia and intact ventricular septum undergoing intervention, and (5) Benefits of pulmonary valve replacement in tetralogy of Fallot patients...
August 8, 2023: Pediatric Cardiology
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