Hamsanandini Radhakrishnan, Chenying Zhao, Valerie J Sydnor, Erica B Baller, Philip A Cook, Damien A Fair, Barry Giesbrecht, Bart Larsen, Kristin Murtha, David R Roalf, Sage Rush-Goebel, Russell T Shinohara, Haochang Shou, M Dylan Tisdall, Jean M Vettel, Scott T Grafton, Matthew Cieslak, Theodore D Satterthwaite
Diffusion Spectrum Imaging (DSI) using dense Cartesian sampling of q-space has been shown to provide important advantages for modeling complex white matter architecture. However, its adoption has been limited by the lengthy acquisition time required. Sparser sampling of q-space combined with compressed sensing (CS) reconstruction techniques has been proposed as a way to reduce the scan time of DSI acquisitions. However prior studies have mainly evaluated CS-DSI in post-mortem or non-human data. At present, the capacity for CS-DSI to provide accurate and reliable measures of white matter anatomy and microstructure in the living human brain remains unclear...
April 2024: Human Brain Mapping